Zotide Injection

By Zotide

Rx

3ml Injection in a Cartridge

Composition icon

Composition

Teriparatide(750mcg)

Manufacturer - Cipla Ltd icon

Manufacturer - Cipla Ltd

Cipla House, Peninsula Business Park, Ganpatrao Kadam Marg, Lower Parel, Mumbai-400013

Expires on or after icon

Expires on or after

January, 2027

About Zotide Injection

Zotide Injection is a synthetic version of parathyroid hormone primarily used in the treatment of severe osteoporosis in men and postmenopausal women who are at high risk for fractures. This medication functions by stimulating the creation of new bone tissue, which serves to enhance bone density and reduce the likelihood of spinal fractures. It is typically administered under the skin or by a healthcare professional. To ensure optimal results, it is important to use it consistently at the same time each day for a recommended period of up to 2 years.

People using Zotide Injection may experience some common side effects like joint pain, injection site reactions, and leg cramps. If any of these side effects persist or cause concern, consulting with a healthcare provider is advised. Prior to starting treatment with Zotide Injection, it is crucial to inform your doctor of any kidney issues or history of kidney stones, as this medication can affect calcium levels in the body. Pregnant and breastfeeding individuals should also seek advice from their healthcare provider before using this medication.

Zotide Injection 3 ml falls under the category of medication known as an anabolic agent, aimed at preventing and managing osteoporosis in adults. This drug assists in strengthening bones and reducing the risk of fractures in the spine and hip. Osteoporosis, a condition characterized by weak and fragile bones, is more commonly seen in older individuals, postmenopausal women, and those who have been on corticosteroid medications for an extended period. Without proper treatment, osteoporosis can lead to bone fractures.

The active ingredient in Zotide Injection 3 ml is Teriparatide, a synthetic form of the human parathyroid hormone that helps regulate calcium metabolism. By promoting new bone formation, increasing bone strength, and bone mass density, Zotide Injection reduces the risk of fractures and enhances bone thickness. This medication is administered by a healthcare professional and should not be self-administered.

While using Zotide Injection 3 ml, some individuals may experience mild side effects like nausea, joint pain, or stomach upset. It is recommended to continue the prescribed course of treatment for optimal results. Patients should seek advice from their doctor if they are pregnant, breastfeeding, or under the age of 18 before taking this medication. Proper storage of Zotide Injection 3 ml in the refrigerator is essential to maintain its efficacy, and it should not be frozen. It is important to inform your healthcare provider before any laboratory testing to avoid any interference with the results.


Benefits

Zotide Injection, a synthetic form of a natural human hormone called parathyroid hormone (PTH), offers numerous benefits in treating osteoporosis. Osteoporosis is a condition that weakens bones, making them fragile and more prone to breaking. This injection is especially helpful for both men and women post-menopause in slowing down the breakdown of bones in the body. By maintaining bone density, Terifrac reduces the risk of bone fractures significantly.

When administered as prescribed by a healthcare professional, Terifrac works by stimulating the body to build new bone, increasing bone strength, and enhancing bone mass density. This not only helps in preventing bone loss after menopause but also aids in the rebuilding of bones. Individuals with weak bones can benefit greatly from this injection, as it reduces the risk of spine and hip fractures, ultimately improving bone health overall.

Moreover, Terifrac can effectively increase bone mass in individuals with osteoporosis and those suffering from glucocorticoid-induced osteoporosis. By encouraging bone formation and enhancing bone thickness, this injection plays a vital role in increasing bone strength and reducing the likelihood of fractures. Supplementing the treatment with regular exercise, a balanced diet rich in calcium and Vitamin D, and minimizing alcohol and tobacco consumption can further enhance the benefits of Zotide Injection in improving bone health.


How to use the Zotide Injection

When you receive Zotide Injection, a healthcare professional will give it to you. It is important not to try to give yourself this medicine. It comes in a 3 ml vial with 750 mcg dose. Your doctor or nurse is trained to properly administer Zotide Injection to ensure it is effective and safe for you. By following their instructions and not attempting to self-administer, you can get the full benefit of the treatment without any risks. It is crucial to trust the healthcare professional handling your Zotide Injection to make sure it is done correctly for your health and well-being.


Uses of Zotide Injection

Zotide Injection is commonly used for the treatment of osteoporosis, particularly in postmenopausal women. It is a medication that can help improve bone density and reduce the risk of fractures caused by osteoporosis. By injecting Terifrac, patients can strengthen their bones and prevent further bone loss. This treatment is especially beneficial for those at a higher risk of developing osteoporosis, such as postmenopausal women. Zotide Injection is a valuable option for individuals looking to manage and improve their bone health.


What conditions Zotide Injection treats?

'Zotide Injection' is used to treat osteoporosis, a condition characterized by weakened and thinning bones. Osteoporosis is more common in older individuals, especially post-menopausal women, and those who have been on long-term corticosteroid medications. Without proper treatment, osteoporosis can lead to bone fractures, often occurring during everyday activities. The most common fractures are at the hip, spine, and wrist, which can result in a stooped posture and restricted movement. Early stages of osteoporosis may not present any symptoms, highlighting the importance of timely intervention to prevent serious complications.


Should you consult a doctor?

For Zotide Injection, seek medical attention if you experience persistent side effects such as joint pain, injection site reactions, nausea, or leg cramps. Contact your doctor if these symptoms do not go away or if you are concerned about them. Additionally, inform your doctor before starting treatment if you have kidney stones, kidney issues, are pregnant, or breastfeeding. It is crucial to follow your doctor's guidance regarding the duration of treatment, typically not exceeding 2 years, even if you start feeling better. Store the injection in the refrigerator between 2°C to 8°C. Regular and timely administration is essential for optimal results, with new bone formation improving bone density and reducing the risk of spinal fractures. Consulting your healthcare professional for any concerns or persistent side effects ensures safe and effective use of Zotide Injection.


Side effects of Zotide Injection

Zotide Injection may cause a variety of side effects, although most of them are not serious and typically resolve as your body gets used to the medication. If any of these side effects persist or cause concern, it's advisable to consult with your healthcare provider. Possible side effects include joint pain, injection site reactions (pain, swelling, redness), nausea, and leg cramps. Some individuals may also experience vomiting, feeling dizzy, tired, or weak, upset stomach, diarrhea, constipation, runny nose, cough, and throat irritation. It is important to be aware of these potential side effects and seek guidance from your doctor if needed.


Safety advice

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liver

Limited information is available about the use of Zotide Injection in patients with liver disease. It is important to consult your doctor for guidance before using this injection to ensure safety and effectiveness. Take necessary precautions and follow your healthcare provider's recommendations closely when considering the use of Zotide Injection if you have liver issues. The impact of Zotide Injection on the liver may vary from person to person, so expert medical advice is crucial in such cases.

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kidney

Zotide Injection should be used cautiously in patients with kidney disease. Dose adjustment may be necessary, so consult your doctor. Avoid using Zotide Injection in individuals with severe kidney disease.

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alcohol

Caution is advised when using Zotide Injection and consuming alcohol. It is important to consult your doctor for guidance.

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driving

When using Zotide Injection, be cautious while driving as it may reduce alertness, cause drowsiness, affect vision, and make you feel dizzy. Avoid driving if these symptoms occur.

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pregnancy

Zotide Injection may not be safe during pregnancy. Animal studies suggest harmful effects on the developing baby. Consult your doctor as there are limited human studies, and risks should be considered before use.

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breastfeeding

It is better to consult your doctor before using Zotide Injection during breastfeeding.


Consumption warning before consuming Zotide Injection

Before consuming Terifrac 750 mcg Injection 3 ml, it is crucial to consider certain factors for your safety. This injection is not suitable for individuals with hypercalcemia, overactive parathyroid gland, metastatic calcification, malabsorption syndrome, kidney stones, moderate renal impairment, Paget’s disease of bone, or a history of skeletal malignancies. Regular monitoring by your doctor is necessary to ensure the proper function of the medication, which may involve blood and urine tests to check for any adverse effects. Terifrac can elevate calcium levels in the blood or urine, so watch for symptoms like nausea, vomiting, constipation, fatigue, or muscle weakness. Pregnant or breastfeeding individuals should consult their doctor before using this injection.

It is not recommended for children, and prolonged use without doctor’s advice should be avoided. If the condition does not improve after completing the course, a doctor should be consulted. Be aware that extended use may increase the risk of cancer. Alcohol consumption with Terifrac should be avoided as it may cause increased drowsiness. Inform your doctor about your health status and medications prior to starting Terifrac to prevent any potential side effects.


What if you forgot to take Zotide Injection?

If you forget to take your Zotide Injection at the scheduled time, try to take it as soon as you remember. But if it's close to the time for your next dose, just skip the missed one and continue with your usual dosing schedule. It's important not to take a double dose to make up for the missed one.


Related lab tests

For patients receiving Zotide Injection, certain lab tests may be necessary to monitor their calcium levels and overall bone health. One important lab test is the serum calcium test, which measures the amount of calcium in the blood. This test helps to assess if the Zotide Injection is affecting calcium levels in the body. Another important lab test is the bone density test, also known as a DEXA scan, which measures the strength and density of bones. This test helps to monitor the effectiveness of Zotide Injection in improving bone density and reducing the risk of fractures. Additionally, tests such as alkaline phosphatase and parathyroid hormone levels can provide valuable information about bone metabolism and calcium regulation in the body. Regular monitoring of these lab tests can help healthcare providers ensure the safety and efficacy of Zotide Injection treatment for patients with osteoporosis.


Additional Information

Habit FormingNo
Chemical ClassParathyroid Hormone Analogs
Therapeutic Class-
Action ClassBone formation stimulator -PTH analogue

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Disclaimer

The information provided on this website is to the best of our abilities to ensure it is accurate, reliable, and reviewed by a team of professionals. It should not be used to diagnose, prevent, or cure any health problem. The information presented here is not intended to create a doctor-patient relationship or replace a registered medical practitioner's advice, diagnosis, or treatment. The absence or provision of any information or warning regarding any medicine should not be assumed as an implied or explicit assurance of safety or efficacy. We highly recommend consulting your registered medical practitioner for all queries or doubts related to your medical condition. Do not ignore professional medical advice or delay seeking it based on the content encountered on our website. We intend to support, not replace, the doctor-patient relationship.

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Dr. Gowri Kulkarni

MBBS - General Medicine, DNB - Psychiatry, MRCGP [INT] Family Medicine, BSIC (BACP)

Last update on 11-Feb-2025