Trombopag 25 Tablet

By Trombopag

Rx

7 Tablet in a Strip

Composition icon

Composition

Eltrombopag(25mg)

Manufacturer - Natco Pharma Ltd icon

Manufacturer - Natco Pharma Ltd

Natco House, Road No.2, Banjara Hills, Hyderabad-500 034, India

Expires on or after icon

Expires on or after

April, 2026

About Trombopag 25 Tablet

Trombopag 25 Tablet, also known as Eltrombopag, is classified as a platelet-stimulating agent used to address low platelet counts in individuals with immune thrombocytopenic purpura (ITP) and hepatitis C virus (HCV) infections. It is also employed in the treatment of severe aplastic anemia. ITP is a condition related to reduced platelet levels, whereas HCV is a liver infection caused by the hepatitis C virus. Severe aplastic anemia is characterized by insufficient blood cell production in the bone marrow.

Eltrombopag, the active ingredient in Trombopag 25 Tablet, falls under the category of thrombopoietin receptor agonists. Thrombopoietin is a hormone that stimulates the creation of megakaryocytes, which in turn aid in regulating platelet production. By enhancing the production of these large bone marrow cells responsible for generating platelets, Trombopag 25 Tablet assists in boosting platelet levels and reducing the risk of bleeding.

It is essential to strictly adhere to the prescribed dosage and duration as directed by your healthcare provider. The tablet is designed to be swallowed whole and preferably taken on an empty stomach. In case of any known allergies to the medication, it is crucial to inform your doctor. Common side effects that may arise include nausea, vomiting, diarrhea, upper respiratory tract infections, and urinary tract infections. It is advisable to notify your doctor if these side effects become problematic, as they might provide suggestions to alleviate or manage them effectively.

Before commencing the use of Trombopag 25 Tablet, it is imperative to inform your doctor about any existing medical conditions and disclose all medications being taken. Patients with liver diseases may require dosage adjustments, hence the importance of consultation with a medical professional in such cases. Additionally, caution should be exercised in elderly patients, and it is advisable to discuss any pregnancy or breastfeeding considerations with your healthcare provider, as Trombopag 25 Tablet may have implications on these situations.


Benefits

Trombopag 25 Tablet offers several benefits in treating specific medical conditions. Firstly, in cases of chronic idiopathic thrombocytopenic purpura (ITP) or Hepatitis C virus (HCV) infection, this medication helps increase the number of platelets in the blood. Low platelet count can lead to a higher risk of bleeding, and Trombopag 25 Tablet works by stimulating the production of platelets to prevent such episodes. This benefit is significant for both adults and children aged 1 year and older suffering from ITP or HCV infection, who have not responded to other treatments.

Moreover, Trombopag 25 Tablet is also effective in managing severe aplastic anemia, a condition where the body fails to generate an adequate amount of new blood cells. When used in combination with other medications, this tablet aids in boosting the production of platelets by increasing megakaryocytes, the bone marrow cells responsible for platelet production. By enhancing the number of platelets in the blood, Trombopag 25 Tablet helps in reducing the risk of bleeding and supports overall health in adults and children aged 2 years and above with severe aplastic anemia.

Overall, the key benefit of Trombopag 25 Tablet lies in its ability to address low platelet count in patients with immune thrombocytopenic purpura, HCV infections, and severe aplastic anemia by stimulating platelet production, thereby reducing the incidence of bleeding episodes and improving the quality of life for individuals affected by these conditions. It is important to follow the doctor's guidance on the dosage and usage of this medication to experience the maximum benefits it offers.


How to use the Trombopag 25 Tablet

To properly use Trombopag 25 Tablet, follow the instructions given to you by your doctor. Swallow the tablet whole with a glass of water on an empty stomach, as directed. Avoid crushing, chewing, or breaking the tablet. If you are prescribed the oral suspension, make sure to shake the bottle well before use. Measure the prescribed dose using the measuring cup, dosing syringe, or dropper provided in the packaging. For the powder form, mix the powder with the recommended amount of water and take it with or without food as per your doctor's instructions. Your physician will determine the appropriate dosage and duration based on factors such as your age, body weight, and medical condition. Always adhere to your doctor's guidance to ensure the safe and effective use of Trombopag 25 Tablet.


Uses of Trombopag 25 Tablet

Trombopag 25 Tablet is primarily used to treat conditions caused by low platelet count, such as immune thrombocytopenia (ITP) and thrombocytopenia in adults with hepatitis C infection. It is also effective in managing low blood count in adults with severe aplastic anemia, a rare blood disorder stemming from bone marrow dysfunction hindering new blood cell production. This medication plays a pivotal role in overcoming these conditions by boosting platelet levels, thereby aiding in blood clotting and overall blood count management.


What conditions Trombopag 25 Tablet treats?

Trombopag 25 Tablet is used to treat immune (idiopathic) thrombocytopenic purpura (ITP), a condition where there are low platelet levels in the blood, leading to abnormal clotting. It is caused by the immune system attacking its own platelets. ITP can also occur in children after a viral infection and symptoms may include easy bruising, bleeding from gums and nose, blood in urine and stools, heavy menstrual flow, and reddish-purple spots on the lower legs. Hepatitis C, an infection and liver inflammation, and severe aplastic anaemia (SAA), where the bone marrow doesn't produce enough blood cells, are other conditions that Revolade can help manage.


Should you consult a doctor?

It is essential to consult your doctor before taking Trombopag 25 Tablet if you have any of the following conditions:

1. At risk of developing blood clots in veins or arteries.
2. Suffering from cancer.
3. Recently undergone surgery or had a physical injury.
4. Obesity.
5. Smoking habits.
6. Cataracts (clouding of the eye lens).
7. Another blood condition like myelodysplastic syndrome.

If you experience any concerning symptoms or side effects while taking Trombopag 25 Tablet, such as unexplained bruising, bleeding, or vision changes, it is important to seek medical attention promptly. Your doctor can provide guidance on the best course of action based on your individual health needs and ensure your safety and well-being.


Side effects of Trombopag 25 Tablet

Common side effects of Trombopag 25 Tablet include nausea, diarrhea, upper respiratory tract infection, vomiting, increased liver enzymes, muscle pain, and urinary tract infection. Other possible side effects may involve headache, tiredness, loss of appetite, fever, anaemia, cough, and tingling or numbness sensations. In rare cases, severe side effects may occur, such as allergic reactions, interruption of blood supply to parts of the heart, blood clots in the lungs or veins, blockade in lung arteries, and liver damage or injury. Additional serious side effects may manifest as heart and blood vessel disorders, nerve damage, gastrointestinal issues like rectal bleeding, skin problems, eye complications, kidney problems, and changes in red blood cell shape. Stop taking Trombopag 25 Tablet and seek immediate medical attention if you experience signs of blood clots, liver problems, or bleeding in the digestive system. It is essential to consult your healthcare provider if you have concerns about the side effects or their persistence.


Safety advice

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liver

When using Trombopag 25 Tablet, it is important to exercise caution if you have a liver disease. Patients with liver conditions may require dose adjustments for this medication. Consulting your doctor before starting Trombopag 25 Tablet is crucial to ensure its safe use.

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kidney

Trombopag 25 Tablet is safe for use in patients with kidney disease. No dose adjustment is needed, but inform your doctor if you have kidney issues. Regular monitoring of kidney function tests is recommended during treatment.

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alcohol

Consult your doctor when consuming alcohol with Trombopag 25 Tablet.

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driving

When taking Trombopag 25 Tablet, be cautious when driving as it may cause dizziness and reduce alertness, impacting your ability to drive safely.

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pregnancy

Trombopag 25 Tablet may not be safe during pregnancy. Animal studies indicate potential harm to the developing baby. Your doctor will assess the risks versus benefits before prescribing. Please consult your doctor before using Trombopag 25 Tablet during pregnancy.

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breastfeeding

Trombopag 25 Tablet is likely unsafe during breastfeeding. Limited data suggests it may pass into breastmilk and harm the baby.


Age above 75(Geriatrics)

Trombopag 25 Tablet should be used with caution in elderly patients (aged 65-years/above). Consult your doctor before taking Trombopag 25 Tablet.

Age below 6 months(Pediatrics)

Trombopag 25 Tablet is not recommended for use in children (aged below 1-year) suffering from immune thrombocytopenia (platelet disorder). It is also not recommended for use in children (aged below 18 years) suffering from low platelet counts due to hepatitis C/severe aplastic anemia. Consult your doctor before taking Trombopag 25 Tablet.

Consumption warning before consuming Trombopag 25 Tablet

Before taking Trombopag 25 Tablet 7's, make sure to tell your doctor if you have any allergies to this medication or other drugs. Inform your healthcare provider about your medical history, especially if you have a history of blood clots, clotting disorders, blood disorders like blood cancer, myelodysplastic syndrome, cataracts, or liver and kidney diseases. It's important to take Trombopag 25 Tablet 7's at least two hours before or four hours after consuming antacids, mineral and vitamin supplements, dairy products, and calcium-enriched foods as they can interfere with its absorption.

Avoid using Trombopag 25 Tablet 7's during pregnancy as it may harm the unborn baby. Consult your doctor before using this medication if you are breastfeeding. Refrain from driving or operating machinery while taking Trombopag 25 Tablet 7's, as it may cause dizziness and tiredness, affecting your ability to concentrate. Limit alcohol intake while on Trombopag 25 Tablet 7's, as it may impact the effectiveness of the medication. This medication is not recommended for children under one year old for ITP and under two years old for SAA.


What if you forgot to take Trombopag 25 Tablet?

If you forget to take a dose of Trombopag 25 Tablet, just skip that missed dose and resume your regular dosing schedule. It is important not to take extra doses to make up for the missed one. If you have any concerns or questions about missed doses, feel free to consult your healthcare provider for further guidance.


What happens if you take overdose of Trombopag 25 Tablet?

In case of taking too much of Trombopag 25 Tablet by accident, it's important to seek immediate medical help. Contact your doctor right away or go to the nearest hospital if you suspect an overdose. Overdose symptoms may occur if the medication is consumed in excessive amounts. It is crucial to get timely medical assistance in such situations to manage and address any potential overdose effects.


Related lab tests

In order to monitor the effects of Trombopag 25 Tablet on your body, the following related lab tests may be done:

1. Complete Blood Count (CBC): This test helps to determine the levels of various blood components such as red blood cells, white blood cells, and platelets. It can provide information on how Revolade is affecting your blood cells.

2. Iron Studies: This test measures the levels of iron in your blood and helps in diagnosing conditions related to iron deficiency or iron overload. It is important to monitor iron levels while taking Revolade.

3. Peripheral Smear Examination: This test involves looking at a sample of your blood under a microscope to examine the size, shape, and number of your blood cells. It can provide additional information on the effects of Revolade on your blood cells.

4. Vitamin B12: Testing your Vitamin B12 levels is important while taking Revolade, as this medication can affect the absorption of B12 in your body. Monitoring B12 levels can help prevent deficiencies that may arise due to the medication.

These lab tests will help your healthcare provider assess the effects of Trombopag 25 Tablet on your body and ensure that you are receiving the best possible care during your treatment.


Additional Information

Habit FormingNo
Chemical ClassBiphenyls Derivatives
Therapeutic Class-
Action ClassThrombopoietin agonist

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Disclaimer

The information provided on this website is to the best of our abilities to ensure it is accurate, reliable, and reviewed by a team of professionals. It should not be used to diagnose, prevent, or cure any health problem. The information presented here is not intended to create a doctor-patient relationship or replace a registered medical practitioner's advice, diagnosis, or treatment. The absence or provision of any information or warning regarding any medicine should not be assumed as an implied or explicit assurance of safety or efficacy. We highly recommend consulting your registered medical practitioner for all queries or doubts related to your medical condition. Do not ignore professional medical advice or delay seeking it based on the content encountered on our website. We intend to support, not replace, the doctor-patient relationship.

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Dr. Abdullah Khan

MBBS - General Medicine

Last update on 01-Oct-2024