Trental 400 Tablet PR, also known as Trental 400 Tablet 15's or TRENTAL, is a medication used to treat conditions related to poor circulation in the arms and legs, such as peripheral vascular disease and intermittent claudication. These conditions cause symptoms like pain, cramping, numbness, and weakness in the legs, especially during physical activities like walking. This medicine belongs to the class of Hemorrheologic agents and Peripheral vasodilators, which work by decreasing the viscosity of blood and improving blood flow through the blood vessels.

The primary action of Trental 400 Tablet PR is to increase blood flow to the arms and legs, thereby reducing cramping and pain experienced by individuals with peripheral vascular disease. It can also alleviate symptoms like numbness or weakness in the legs while walking. The medication helps in improving circulation in the small blood vessels of the hands and feet, allowing for better mobility and reduced discomfort during physical activities. Trental 400 Tablet PR is particularly recommended for patients whose symptoms have not improved with lifestyle changes like quitting smoking and regular exercise.

Patients are advised to take Trental 400 Tablet PR regularly as prescribed by their doctor. It should be taken with food at a fixed time to ensure optimal effectiveness. Abruptly stopping the medication without consulting the doctor is not recommended, as it may lead to unpleasant side effects. Common side effects of Trental 400 Tablet PR include nausea, vomiting, diarrhea, headache, flushing, weakness, and other gastrointestinal symptoms. It is important to inform the doctor about any existing liver or kidney disease and other medications being taken regularly.

TRENTAL, which contains the active ingredient Pentoxifylline, is another formulation used in the treatment of peripheral vascular disease and intermittent claudication. Pentoxifylline works in a similar way by reducing blood viscosity and improving blood flow in narrowed blood vessels. Individuals with conditions like heart problems, recent heart attack, stroke with bleeding in the brain, or bleeding in the eye should not use TRENTAL. Pregnant or breastfeeding women should consult their doctor before taking the medication. Common side effects of TRENTAL include bloating, diarrhea, flushing, nausea, stomach discomfort, and vomiting.

In summary, Trental 400 Tablet PR and TRENTAL are medications designed to improve blood circulation in individuals with peripheral vascular disease and intermittent claudication. They are intended to alleviate symptoms like leg pain, cramping, and weakness, allowing for better mobility and quality of life. Proper dosing, regular intake as advised, and lifestyle modifications are essential for optimal treatment outcomes.

Trental 400 Tablet PR offers several benefits in treating conditions such as peripheral vascular disease and intermittent claudication. In cases of peripheral vascular disease, where there is disrupted blood circulation in blood vessels, this medication plays a crucial role in preventing blood clot formation in veins and arteries. By ensuring smooth blood flow throughout the body, it helps reduce the risk of heart attacks, strokes, deep vein thrombosis, and pulmonary embolism. Additionally, Trental 400 Tablet PR not only stops the enlargement of existing blood clots but also inhibits their formation. To enhance the effectiveness of this medication, it is advisable to make positive lifestyle changes like maintaining a healthy diet and staying physically active.

For individuals experiencing intermittent claudication, which manifests as muscle pain in the legs during exercise or walking, Trental 400 Tablet PR can provide relief. This pain is typically caused by insufficient blood supply to the legs, and the medication works to improve blood flow, prevent blood clotting, and promote unrestricted blood circulation in the body. By containing Pentoxyfilline—an active ingredient known as a peripheral vasodilator—this tablet effectively reduces the viscosity of blood, allowing it to flow more easily through blood vessels, especially in the extremities. Moreover, Trental 400 Tablet PR can increase the distance one can walk without experiencing pain, owing to its ability to enhance blood circulation in the legs.

Patients who have not seen an improvement in their pain levels despite making lifestyle changes like ceasing smoking and engaging in regular exercise may benefit from Trental 400 Tablet PR. By addressing the root causes of peripheral vascular disease and intermittent claudication, this medication serves as a valuable treatment option for those seeking relief from associated symptoms and complications.

To use Trental 400 Tablet PR, follow the instructions given by your doctor or check the label for guidance. It is important to take this medication with food. When taking Trental 400 Tablet PR, swallow the whole tablet with water; do not chew or crush it. Your physician will determine the appropriate dosage and duration of treatment based on factors such as your age, body weight, and medical condition. Remember to always swallow the tablet with a glass of water and do not crush or chew it. Follow your doctor's advice carefully for the best results.

Trental 400 Tablet PR is commonly used for the management of peripheral vascular disease and intermittent claudication. Peripheral vascular disease causes poor circulation to the arms and legs, leading to symptoms such as intermittent claudication - pain while walking or at rest due to inadequate blood flow to the legs. By improving blood flow, Trental 400 Tablet PR can help alleviate these symptoms and improve the overall condition of individuals with these conditions.

Trental 400 Tablet PR is used to treat intermittent claudication, a condition that causes cramp-like leg pain during walking due to poor blood flow in the legs.

Seek medical advice promptly if you experience symptoms such as dizziness, light-headedness, or fainting when changing positions quickly, as this may indicate low blood pressure. It is important to consult a healthcare professional if you have recently undergone surgery or have a history of peptic ulcers. Additionally, if you had a stroke involving bleeding in the brain or if you have had eye bleeding in the past, it is crucial to seek medical attention before starting Trental 400 Tablet PR. These conditions may require special monitoring or alternative treatment options to ensure your safety and well-being.

When taking Trental 400 Tablet PR, some common side effects may occur as your body gets used to the medication. These include bloating, diarrhea, flushing (a warm sensation in the face, ears, neck, and trunk), headache, heartburn, lightheadedness, nausea, stomach discomfort, vomiting, and weakness. You may also experience additional side effects such as abdominal pain, constipation, urine discoloration, and sleep problems. Some more serious side effects that require immediate medical attention include allergic reactions, bleeding under the skin, blood in vomit or stools, aseptic meningitis, easier bruising, increased heart rate, chest pain, irregular heartbeat, and frequent infections like chills, fever, sore throat, or mouth ulcers. If you notice any of these severe side effects, stop taking Trental and contact your doctor right away. It's essential to consult your healthcare provider if you experience persistent side effects or have any concerns.

Trental 400 Tablet PR should be used with caution in elderly patients (aged 65 years and above). Usually, the treatment will be initiated with the lowest effective dose depending upon kidney function and your doctor may monitor your kidney function throughout treatment with Trental 400 Tablet PR. Consult your doctor before taking it.

Trental 400 Tablet PR is generally not suitable for use in children and adolescents under 18 years of age. Contact child’s doctor for advice. 

Before consuming Trental 400 Tablet PR , ensure that you are not allergic to any of its components. Notify your doctor if you are pregnant, breastfeeding, or if you are using blood thinners, as this may increase the risk of severe bleeding. Remember that Trental 400 Tablet PR is not meant for long-term use unless prescribed by a physician. Inform your doctor if you have a history of brain or retinal bleeding, low blood pressure, heart attack, kidney disease, or liver disease. Always disclose your use of Trental 400 Tablet PR before any dental or surgical procedures. Do not abruptly stop taking this medication without consulting your doctor, as it may cause unpleasant side effects. Additionally, continue necessary lifestyle changes alongside Trental 400 Tablet PR for optimal results and a swift recovery.

If a dose of Trental 400 Tablet PR is missed, it is advised to skip the missed dose and resume with the regular dosing schedule. Avoid doubling up on the dose to make up for the missed one. It's important to maintain consistent usage of Trental 400 Tablet PR as directed by your healthcare provider for the best results.

If you or someone takes too much Trental 400 Tablet PR, it's crucial to seek medical help promptly by contacting your doctor or going to the nearest hospital. Overdosing on Trental 400 Tablet PR can lead to symptoms such as low blood pressure, drowsiness, seizures, or irregular heartbeat. If an overdose is suspected, it is important to act quickly to receive the necessary medical attention and care.

When taking Trental 400 Tablet PR, it is important to monitor your liver function to ensure that the medication is not causing any harm to your liver. Your healthcare provider may recommend liver function tests to check the health of your liver while on Trental 400. These tests can help in monitoring liver enzymes such as alanine aminotransferase (ALT), aspartate aminotransferase (AST), alkaline phosphatase, and bilirubin levels. Monitoring liver function through these tests can help detect any potential liver damage early on and allow for prompt intervention if needed. Regular liver function tests are important for ensuring your overall health and safety while taking Trental 400 Tablet PR.