Tofe-ER Tablet

By Tofe

Rx

10 Tablet ER in a Strip

Composition icon

Composition

Tofacitinib(11mg)

Manufacturer - Alkem Laboratories Ltd icon

Manufacturer - Alkem Laboratories Ltd

Alkem Laboratories Limited, Devashish Building, Alkem House, Senapati Bapat Road, Lower Parel, Mumbai - 400 013.

Expires on or after icon

Expires on or after

April, 2026

About Tofe-ER Tablet

Tofe-ER Tablet, also known as Tofacitinib, is a medication used to manage moderate to severe conditions such as rheumatoid arthritis, psoriatic arthritis, ankylosing spondylitis, and ulcerative colitis. These are inflammatory diseases that affect the joints and tissues in the body, causing pain, swelling, and discomfort. Tofe-ER Tablet works by targeting inflammation and reducing pain, tenderness, and swelling in the affected joints. It also plays a role in slowing down the progression of bone and joint damage.

It is important to follow your doctor's instructions when taking Tofe-ER Tablet. The dosage of the medication will depend on your specific condition and any other medications you may be using. It is recommended to take the tablets at the same time each day, with or without food. It is crucial not to stop taking the medicine without consulting your doctor, as discontinuing the treatment abruptly could exacerbate your condition.

Like any medication, Tofe-ER Tablet may have side effects. The most common ones include upper respiratory tract infections, headaches, diarrhea, and nasopharyngitis. While these side effects are typically manageable and tend to resolve over time, there are other, less common but serious side effects such as blood clots and tears in the stomach or intestine wall that require immediate medical attention. If you have concerns about the side effects, it is advisable to speak with your doctor.

Prior to starting Tofe-ER Tablet, you may need to undergo blood tests, and it is essential not to commence the treatment if you have an active infection. Inform your doctor if you have a history of certain conditions such as tuberculosis, shingles, kidney or liver disease, hepatitis B or C, or blood clots in your legs or lungs. Due to the potential for increased susceptibility to infections, it is recommended to avoid contact with individuals who have contagious illnesses like chickenpox or the flu. Tofe-ER Tablet is not suitable for individuals under 18 years old, pregnant women, or breastfeeding mothers, unless specifically advised by a doctor.

In summary, Tofe-ER Tablet is a medication that can help alleviate symptoms associated with various inflammatory conditions, but it is essential to use it as directed by your healthcare provider and remain vigilant about any potential side effects or complications.


Benefits

Tofe-ER Tablet offers a range of benefits for individuals dealing with different conditions. For those suffering from Rheumatoid arthritis, this medication works by inhibiting the action of certain chemicals that trigger inflammation in the body. By doing so, Tofe-ER Tablet helps alleviate pain, stiffness, and swelling in the joints. Additionally, it plays a crucial role in slowing down the progression of bone and joint damage, enabling individuals to carry out daily activities more comfortably. By maintaining a consistent daily dosage, patients can experience the maximum benefits of this medication, even if they start feeling better, as it works not only to address current symptoms but also as a preventive measure for future harm.


Similarly, for individuals with Psoriatic arthritis, which is linked to the skin condition psoriasis, Tofe-ER Tablet proves beneficial in reducing joint pain, stiffness, and swelling associated with the disease. Moreover, it helps enhance flexibility and hinders disease progression, ultimately contributing to an improved quality of life for those affected.


In the case of Ankylosing spondylitis, a specific form of arthritis affecting the spine and large joints, Tofe-ER Tablet plays a pivotal role in alleviating pain, stiffness, and swelling in the spinal and joint areas. By enhancing flexibility and impeding disease advancement, this medication empowers individuals to lead more active and fulfilling lives.


Furthermore, for individuals grappling with Ulcerative colitis, a condition affecting the large intestine and rectum, Tofe-ER Tablet aids in relieving symptoms such as intestinal inflammation, bleeding, diarrhea, and abdominal pain. By managing these distressing symptoms effectively, this medication contributes to the overall well-being of patients and helps prevent the recurrence of these issues. Adequate fluid intake alongside treatment with Tofe-ER Tablet is advised to support hydration and optimize the therapeutic benefits of the medication.


Overall, Tofe-ER Tablet emerges as a valuable treatment option for various inflammatory conditions, offering symptom relief, disease progression prevention, enhanced flexibility, and an improved quality of life for individuals facing challenges associated with Rheumatoid arthritis, Psoriatic arthritis, Ankylosing spondylitis, and Ulcerative colitis.


How to use the Tofe-ER Tablet

To use Tofe-ER Tablet, follow the instructions provided by your doctor carefully. Swallow the tablet whole with a glass of water. Do not chew, crush, or break the tablet. It is recommended to take Tofe-ER Tablet at a fixed time each day. You may take it with or without food, as advised by your physician. Your doctor will determine the appropriate dose and duration of treatment based on factors such as your age, medical condition, and body weight. If needed, the tablet can be crushed and taken with water, but make sure to seek guidance from your healthcare provider before doing so. Remember to take Tofe-ER Tablet exactly as prescribed for the best results.


Uses of Tofe-ER Tablet

Tofe-ER Tablet is primarily used in the treatment of Rheumatoid arthritis, Psoriatic arthritis, Ankylosing spondylitis, and Ulcerative colitis. These conditions are characterized by inflammation and pain in the joints and gastrointestinal tract. Tofe-ER Tablet helps to reduce these symptoms and improve the overall quality of life for individuals suffering from these conditions. Additionally, it may also be prescribed for other similar conditions like polyarticular juvenile idiopathic arthritis and juvenile psoriatic arthritis. By targeting the underlying inflammatory processes, Tofe-ER Tablet provides relief and helps patients manage their symptoms effectively.


What conditions Tofe-ER Tablet treats?

Tofe-ER Tablet is used for treating conditions like rheumatoid arthritis, psoriatic arthritis, and ulcerative colitis. Rheumatoid arthritis is an auto-immune disease that causes joint pain, swelling, and stiffness. Psoriatic arthritis is an inflammatory arthritis that affects large joints and can be linked to psoriasis. Ulcerative colitis is a chronic inflammatory bowel disease that leads to inflammation and ulcers in the colon, with symptoms like bloody stools and stomach pain. These conditions can also result in other symptoms such as joint pain, mouth sores, and skin problems.


Should you consult a doctor?

Seek medical advice or consult a doctor before using Tofe-ER Tablet if you have a severe bloodstream infection. Before taking this medication, inform your doctor if you have or are being treated for any infections, or experiencing symptoms such as fever, muscle aches, cough, weight loss, or difficulty swallowing. Let your doctor know if you have conditions that weaken the immune system, a history of recurrent infections, cancer, or smoke regularly. Additionally, inform your healthcare provider if you have inflammation of the large intestine, ulcers in the stomach or intestines, high cholesterol, or are at risk of developing blood clots. It is important to mention if you have lactose intolerance or are planning to undergo vaccination or have recently had major surgery. Tofe-ER Tablet is not recommended for children under 2 years of age.


Side effects of Tofe-ER Tablet

When taking Tofe-ER Tablet, some common side effects may occur as your body gets used to the medicine. These include upper respiratory tract infections, headaches, diarrhea, and nasopharyngitis, which is an inflammation of the throat and nasal passages. Other reported side effects can range from mild to severe and include symptoms like vomiting, nausea, high blood pressure, cold sores, joint swelling, abnormal sensations, muscle pain, and weight gain. More serious side effects that require immediate medical attention include signs of serious infections, ulcers or perforations in the stomach, allergic reactions, blood clots in lungs or veins, and heart attack symptoms such as chest pain, shortness of breath, and dizziness. If any of these severe side effects occur, it is crucial to stop taking the medication and contact your doctor right away for further guidance and evaluation.


Safety advice

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liver

Tofe-ER Tablet requires caution when used by individuals with severe liver disease. It may be necessary to adjust the dosage of Tofe-ER Tablet in such cases. It is important to consult your doctor regarding the appropriate use of this medication.

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kidney

Tofe-ER Tablet needs caution in severe kidney disease. Dosage adjustment may be necessary. Always consult your doctor for guidance.

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alcohol

When consuming alcohol with Tofe-ER Tablet, it does not result in any harmful side effects.

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driving

When taking Tofe-ER Tablet, it is generally safe to drive as it does not typically impact your driving abilities.

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pregnancy

Tofe-ER Tablet may not be safe during pregnancy. Animal studies suggest potential harm to the developing baby. Your doctor will evaluate the benefits and risks before prescribing. Consult your doctor for guidance.

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breastfeeding

Tofe-ER Tablet is likely not safe during breastfeeding, as it may pass into breastmilk and potentially harm the baby.


Age above 75(Geriatrics)

Tofe-ER Tablet should be used with caution in patients above the age of 65 years of age as they may be at increased risk of infections, heart attack and some types of cancer. Consult with your doctor before taking it.


Consumption warning before consuming Tofe-ER Tablet

Before consuming Tofe-ER Tablet, it is crucial to be aware of certain warnings. Do not take this medication if you have allergies to its components or if you are dealing with severe infections like bloodstream infection, active tuberculosis, or severe liver issues such as cirrhosis. Avoid Tofe-ER Tablet if you are pregnant, breastfeeding, or if you have certain health conditions like chronic lung disease, hepatitis B/C, cancer, or kidney problems. Inform your healthcare provider about any infections, immune-affecting medications, tuberculosis history, or close contact with tuberculosis patients. Additionally, if you have heart problems, diabetes, high blood pressure, or blood clotting issues, consult your doctor before using this medication. It is not advised for children under 18 years due to lack of established safety and effectiveness. Regularly update your doctor on your health status and medications to prevent any potential side effects.


Disease interactions

In some cases, Tofe-ER Tablet may not be suitable for individuals with certain health conditions. It is important to inform your healthcare provider if you have infections, bloodstream infection, severe liver problems, tuberculosis, blood clot issues, diabetes, high cholesterol, intestinal perforation, or gastrointestinal obstruction. These conditions may interact with the medication and require close monitoring or adjustments to your treatment plan to ensure your safety and efficacy of the drug. Always disclose your full medical history to your doctor to avoid any potential complications or negative interactions with Tofe-ER Tablet.


What if you forgot to take Tofe-ER Tablet?

If you forget to take your Tofe-ER Tablet, take it as soon as you remember. If it's close to the time for your next dose, simply skip the missed one and continue with your usual dosing schedule. It's important not to take a double dose to make up for the missed one. Just take the next scheduled dose as prescribed.


What happens if you take overdose of Tofe-ER Tablet?

In the event that you or someone else unintentionally consumes an excessive amount of Tofe-ER Tablet, it is crucial to seek assistance promptly. You should contact your doctor without delay or head to the nearest hospital. It is important to address any potential concerns regarding overdose and take appropriate action to ensure your well-being.


Related lab tests

Related Lab Tests to consider when taking Tofe-ER Tablet include Anti Neutrophilic Cytoplasmic Antibody (ANCA) test, C-reactive Protein (CRP) Quantitative test, Erythrocyte Sedimentation Rate (ESR) test, HLA-B27 PCR test, Rheumatoid Factor Agglutination test, Rheumatoid Factor Turbidometry test, and Rheumatoid Factor IgG Antibody test. These tests help monitor inflammation levels, autoantibodies, and specific markers related to rheumatic conditions, which can be important factors to consider when using Tofe-ER Tablet. Additionally, X-ray and MRI scans may be recommended to assess joint damage and disease progression. Regular monitoring of Complete Blood Count (CBC) can help track any potential side effects on blood cells. Skin tests may be performed to check for allergic reactions. Lastly, liver and kidney function tests are advisable to monitor the impact of the medication on these organs.


Additional Information

Habit FormingNo
Chemical ClassPyrrolo Pyrimidine Derivative
Therapeutic ClassPAIN ANALGESICS
Action ClassJanus kinase inhibitors

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Disclaimer

The information provided on this website is to the best of our abilities to ensure it is accurate, reliable, and reviewed by a team of professionals. It should not be used to diagnose, prevent, or cure any health problem. The information presented here is not intended to create a doctor-patient relationship or replace a registered medical practitioner's advice, diagnosis, or treatment. The absence or provision of any information or warning regarding any medicine should not be assumed as an implied or explicit assurance of safety or efficacy. We highly recommend consulting your registered medical practitioner for all queries or doubts related to your medical condition. Do not ignore professional medical advice or delay seeking it based on the content encountered on our website. We intend to support, not replace, the doctor-patient relationship.

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Dr. Preeti Kumar

MBBS, DGO - Obstetrics and Gynaecology, DNB - Obstetrics and Gynaecology

Last update on 01-Oct-2024