Themiset 75mg Injection
By Themiset
Rx
1ml Injection in a Vial

Composition
Palonosetron(75mg)

Manufacturer - Themis Medicare Ltd
11/12, Udyog Nagar, S. V. Road, Goregaon (W), Mumbai- 400104.

Expires on or after
April, 2026
About Themiset 75mg Injection
Themiset 75mg Injection is a medication commonly used as an antiemetic to help control nausea and vomiting caused by various medical conditions such as stomach upset. It is also effective in preventing nausea and vomiting resulting from surgeries, cancer treatment, or radiotherapy. This injection is typically administered under the supervision of a healthcare professional and can be used alone or in combination with other medications as deemed appropriate by your doctor. The dosage will be determined by your healthcare provider based on your specific needs, and it is crucial to continue the injections until your doctor advises otherwise, after which tablets may be prescribed as a substitute.
Common side effects of Themiset 75mg Injection include pain at the injection site, headaches, and constipation. Some individuals may also experience dizziness and drowsiness, so it is advisable to avoid activities that require mental alertness until you understand how the medicine affects you. These side effects usually fade away once the medication is discontinued, but if they persist or become bothersome, it is advisable to consult your doctor for possible solutions or adjustments. Prior to taking Themiset 75mg Injection, inform your doctor about any heart or liver issues, stomach or intestinal blockages, or any other medications you are currently using, especially those for epilepsy, heart conditions, cancer, or depression. If you are pregnant or nursing, seek guidance from your healthcare provider.
Themiset 75/1.5mg Injection is classified as an antiemetic for chemotherapy-induced nausea and vomiting. Nausea refers to stomach discomfort often preceding vomiting, which is the expulsion of stomach contents through the mouth. This injection contains Palonosetron, which functions by blocking serotonin, a brain chemical that triggers the vomiting center. Administered by a healthcare professional, this medication may be accompanied by side effects like diarrhea, constipation, dizziness, and headaches, which usually subside over time and do not necessitate medical intervention unless they persist or worsen. Notify your doctor if you are allergic to Themiset 75/1.5mg Injection or any other medicines, and disclose any pregnancy or breastfeeding status. Drive cautiously due to potential drowsiness or dizziness, and consider consuming light, frequent meals and staying well-hydrated while on this medication.
Themiset Injection containing Palonosetron falls under the category of Serotonin antagonists, indicated for managing chemotherapy-induced nausea and vomiting as well as postoperative nausea and vomiting. Prior to receiving Themiset Injection, inform your doctor about your medical history, particularly if you have heart conditions, bowel issues, or family history of heart diseases. Avoid using this medication during pregnancy unless essential, as its effects on the unborn child are not fully understood. Likewise, exercise caution regarding breastfeeding while on Themiset Injection. The use of this medication in children and elderly individuals requires careful consideration and consultation with a healthcare provider, with the most common side effect reported being headaches. If adverse symptoms worsen, contact your physician promptly.
Benefits
Themiset 75mg Injection offers valuable benefits in managing nausea and vomiting, particularly in individuals undergoing cancer treatment like chemotherapy or radiation therapy. By blocking the action of certain chemicals in the body responsible for inducing these discomforting symptoms, this medication helps patients cope better with the side effects of their treatments. Notably, Themiset 75mg Injection is known to be effective in both adults and children, making it a versatile solution for various age groups. Additionally, it also aids in reducing nausea and vomiting post-surgery in adults. Administered as an injection by healthcare professionals, the dosage of Themiset 75mg Injection is tailored to suit the specific needs of each patient, ensuring optimal results. It is crucial to emphasize the importance of not self-administering this medication to prevent any adverse effects. Overall, the use of Themiset 75mg Injection provides patients with a chance to recover more comfortably from their medical procedures while minimizing the impact of nausea and vomiting on their quality of life.
How to use the Themiset 75mg Injection
When it comes to using Themiset 75mg Injection, it is important to note that only a healthcare professional should administer this medication. It should not be self-administered under any circumstances. Your doctor or nurse will be the ones to inject the Themiset 75mg Injection into your body, typically intravenously. The dosage and duration of the injection will be determined by your doctor based on factors such as your age, body weight, and the specific disease condition being treated. It is crucial to follow your healthcare provider's instructions carefully and not attempt to administer this injection on your own. Your safety and well-being are of utmost importance, so always rely on the expertise of medical professionals when using Themiset 75mg Injection.
Uses of Themiset 75mg Injection
Themiset 75mg Injection is commonly used to manage nausea and vomiting caused by chemotherapy in cancer patients. It can also be prescribed for postoperative nausea and vomiting after surgery. This injection helps control the feelings of nausea and prevents vomiting in these specific situations.
What conditions Themiset 75mg Injection treats?
Nausea and vomiting are not diseases but symptoms of various conditions such as infections, motion sickness, early pregnancy, and gastroparesis. These symptoms are controlled by a brain receptor called the chemoreceptor zone (CTZ). Nausea refers to stomach discomfort, often preceding vomiting, which is the forceful emptying of stomach contents through the mouth.
Should you consult a doctor?
If you are considering receiving Themiset 75mg Injection, it is important to consult your doctor if you have a history of acute bowel obstruction or chronic constipation. Additionally, before taking this injection, inform your doctor if there are any imbalances in minerals like potassium and magnesium in your blood that are not being treated. Seeking medical attention is crucial if you experience any worsening of these conditions or any new symptoms after receiving the injection. Your doctor will be able to provide guidance and necessary treatment adjustments to ensure your safety and well-being.
Side effects of Themiset 75mg Injection
When using Themiset 75mg Injection, some common side effects may occur as your body gets used to the medication. These can include injection site pain, constipation, headache, diarrhea, and dizziness. While most of these side effects are not severe and may go away on their own, it is important to consult your doctor if they persist or if you are concerned about them.
In some cases, more serious side effects might occur, requiring prompt medical attention. These can include changes in blood pressure, irregular heart rate, widening or discoloration of veins, alterations in potassium levels in the blood, increased blood or urine sugar levels, low calcium levels in the blood, increased bilirubin, elevated liver enzymes, anxiety, difficulty sleeping, loss of appetite, weakness, tiredness, fever, or flu-like symptoms. Additionally, skin reactions such as numbness, burning, prickling, tingling, itching, or rashes, eye irritation or impaired vision, motion sickness, tinnitus (ringing in the ear), hiccups, flatulence, dry mouth, indigestion, stomach ache, difficulty urinating, joint pain, jerky body movements, abnormal heart rate, cough, shortness of breath, nosebleeds, hives, fever, or pain at the injection site, especially in children, may occur.
It is also important to be aware of potential side effects such as headache, dizziness, constipation, diarrhea, and heart rhythm changes (QT prolongation) or slow heartbeat, which should be monitored closely. Should you experience severe allergic reactions such as hives, swollen face, difficulty breathing, or chest pain, it is crucial to discontinue the Themiset Injection immediately and seek medical attention.
Safety advice

liver
When using Themiset 75mg Injection, patients with liver disease can take it safely, and there is no need to adjust the dosage. This medication does not require any specific dose changes for individuals with liver issues.

kidney
Themiset 75mg Injection is safe for patients with kidney disease and does not require dose adjustment.

alcohol
It is unclear whether consuming alcohol with Themiset 75mg Injection is safe. Please consult your doctor.

driving
Themiset 75mg Injection can reduce alertness, affect vision, cause sleepiness, and dizziness. Avoid driving if experiencing these effects.

pregnancy
Themiset 75mg Injection is generally safe for use in pregnancy. Animal studies indicate minimal risks to the baby, but human studies are limited.

breastfeeding
Themiset 75mg Injection is likely safe during breastfeeding, as limited data shows no significant risk to the baby.
Age above 75(Geriatrics)
Age below 6 months(Pediatrics)
Consumption warning before consuming Themiset 75mg Injection
Before taking Themiset 75mg Injection, make sure to inform your doctor if you are allergic to this medication or any other medicines. This injection can be administered to children above 1 month old based on their body weight, following the doctor's instructions. If you are pregnant or breastfeeding, it is important to consult your doctor before using Themiset 75mg Injection. Be cautious while driving, as this medication may cause tiredness or dizziness. It is advisable to avoid heavy meals and instead opt for small, nourishing snacks throughout the day. Stay hydrated by drinking plenty of water to prevent dehydration.
What if you forgot to take Themiset 75mg Injection?
If you forget to take your scheduled dose of Themiset 75mg Injection, try to take it as soon as you realize it. But, if it's already close to the time for your next dose, it's better to skip the missed one and continue with your regular dosing schedule. It's important not to take a double dose to make up for the missed one. Remember that consistency in taking your medication is crucial for its effectiveness.
What happens if you take overdose of Themiset 75mg Injection?
The Themiset 75mg Injection is given directly into the body through a vein by a doctor, reducing the risk of an overdose. However, in rare cases where an overdose does occur, it can result in symptoms such as seizures, difficulty breathing, paleness, bluish skin discoloration, and sudden collapse. These signs indicate that too much of the medication has been administered at once. It is crucial to seek immediate medical attention if these symptoms are observed to prevent any serious complications.
Related lab tests
The lab tests related to Themiset 75mg Injection include a complete blood count and an ECG. A complete blood count, also known as CBC, measures various components of blood, such as red blood cells, white blood cells, and platelets. This test helps in assessing overall health and detecting possible medical conditions. An ECG, which stands for electrocardiogram, is a test that records the electrical activity of the heart. It is used to evaluate heart rhythm and detect any abnormalities in the heart's functioning. These lab tests are important in monitoring the effects of Themiset 75mg Injection and ensuring the patient's safety and well-being.
Additional Information
Habit Forming | No |
Chemical Class | Isoquinoline and Quinuclidine Derivative |
Therapeutic Class | GASTRO INTESTINAL |
Action Class | Serotonin antagonists (5-HT3 antagonists) |
FAQs
Disclaimer
The information provided on this website is to the best of our abilities to ensure it is accurate, reliable, and reviewed by a team of professionals. It should not be used to diagnose, prevent, or cure any health problem. The information presented here is not intended to create a doctor-patient relationship or replace a registered medical practitioner's advice, diagnosis, or treatment. The absence or provision of any information or warning regarding any medicine should not be assumed as an implied or explicit assurance of safety or efficacy. We highly recommend consulting your registered medical practitioner for all queries or doubts related to your medical condition. Do not ignore professional medical advice or delay seeking it based on the content encountered on our website. We intend to support, not replace, the doctor-patient relationship.
₹163
Inclusive of all taxes
Content verified by

Dr. Archana Prabhakar
MBBS, M.Med (Family Medicine)
Last update on 01-Oct-2024