Terlistat Injection
By Terlistat
Rx
10ml Injection in a Vial

Composition
Terlipressin(1mg)

Manufacturer - Samarth Life Sciences Pvt Ltd
Samarth House, 168, Bangur Nagar, Off Link Road, Near Ayappa Temple & Kallol Kali Temple, Goregaon (W), Mumbai - 400 090.

Expires on or after
April, 2026
About Terlistat Injection
Terlistat Injection, also known as Terlistat Injection 10ML, falls under the category of vasopressin receptor agonists. It is mainly used to treat bleeding esophageal varices, which are dilated veins in the food pipe leading to the stomach. The medication can also be used in emergency situations for treating type 1 hepatorenal syndrome in patients with liver cirrhosis and ascites.
The active ingredient in Terlistat Injection is Terlipressin, a synthetic hormone that breaks down in the body to release lysine vasopressin. This substance is effective in stopping bleeding from varicose veins in the food pipe by narrowing the affected blood vessels and controlling the blood flow through them. This mechanism helps in managing and controlling the bleeding effectively.
For the administration of Terlistat Injection, it is crucial to note that it should only be given by a healthcare professional. Self-administration of this medication at home is strictly advised against. The dosage and frequency of the injection will be determined by your doctor based on the severity of the condition and the individual's specific needs.
While Terlistat Injection is a beneficial treatment option, it may come with some common side effects. These can include headaches, diarrhoea, abdominal cramps, fluctuations in blood pressure, slow heart rate, pale skin, and decreased blood circulation in the arms, legs, and skin. Most of these side effects are mild and tend to resolve on their own over time. However, if any side effects persist or worsen, it is essential to consult your doctor promptly.
Before starting treatment with Terlistat Injection, it is important to inform your healthcare provider about any underlying heart, liver, or kidney issues you may have. Additionally, disclose all other medications you are currently taking to ensure there are no potential interactions that could affect your treatment. This medication is not recommended for children and adolescents, and special consideration should be given to pregnant or breastfeeding women and elderly individuals above the age of 70.
Terlistat Injection proves to be a valuable and effective option for managing bleeding esophageal varices and hepatorenal syndrome when used under the supervision of a healthcare professional and with proper consideration of individual health conditions and potential side effects.
Benefits
Terlistat Injection can be highly beneficial in treating bleeding esophageal varices. These varices occur when normal blood flow to the liver is obstructed by a clot or scar tissue. The injection works by narrowing the blood vessels, which in turn reduces blood flow and helps to diminish and eventually stop the bleeding. It is essential to note that this injection should only be administered by a qualified medical professional and should not be selfadministered. Following the doctor's precise instructions is crucial to ensure you receive the maximum benefit from this medication.
How to use the Terlistat Injection
When using Megtril 1mg Injection, it is important to remember that only a doctor or nurse should administer this medication. It is not safe to self-administer this injection. Your healthcare provider will determine the appropriate dose and administer the injection for you. It is important to follow their instructions carefully and not attempt to give yourself the injection. Always consult your doctor or nurse if you have any questions or concerns about how to use Megtril 1mg Injection. By allowing a healthcare professional to handle the administration of this medication, you can ensure your safety and well-being.
Uses of Terlistat Injection
Megtril 1mg Injection is mainly used to treat bleeding esophageal varices. Esophageal varices are enlarged blood vessels in the esophagus that can rupture and bleed, posing a serious health risk. This medication helps to control and stop the bleeding from these varices, preventing further complications. It is an important treatment option for managing this condition and ensuring the patient's wellbeing.
What conditions Terlistat Injection treats?
Terlistat Injection is used to treat bleeding esophageal varices, which are caused by dilated veins in the food pipe leading to the stomach. This medication works by narrowing the walls of blood vessels and reducing blood flow into the affected veins. It is administered by a healthcare professional to patients experiencing severe or lifethreatening bleeding in the esophagus. Common side effects may include headaches, slow heart rate, high blood pressure, peripheral vasoconstriction, and peripheral ischemia. Inform your doctor about any persistent or worsening side effects. Prior to use, disclose any heart, liver, or kidney issues, and all other medications you are taking. This medicine is not recommended for children and adolescents.
Should you consult a doctor?
If you experience severe bleeding in the food pipe, known as bleeding esophageal varices, it is important to seek medical help immediately. Terlistat Injection is specifically given by healthcare professionals to treat severe or lifethreatening bleeding in the esophagus. It is crucial not to selfadminister this medicine at home, as your doctor will determine the correct dosage and frequency of administration.
While using Terlistat Injection, be aware of common side effects like headaches, slow heart rate, high blood pressure, peripheral vasoconstriction, and peripheral ischemia. If these side effects persist or worsen, inform your doctor promptly. Before using this medicine, discuss any existing heart, liver, or kidney issues with your doctor and disclose all other medications you are currently taking. Note that Terlistat Injection is not suitable for children or adolescents.
Remember, most side effects typically diminish as your body adjusts to the medicine. However, if you have concerns about any side effects or if they persist, do not hesitate to consult your doctor for further guidance.
Side effects of Terlistat Injection
When taking Megtril 1mg Injection, you may experience some side effects. These side effects are usually mild and may go away as your body gets used to the medication. If you are concerned or if the side effects persist, it is important to speak with your doctor.
Some of the potential side effects of Megtril 1mg Injection include:
Headache: You may experience a headache while using this medication. It is advisable to inform your doctor if this side effect becomes bothersome.
Slow heart rate: Some individuals may notice a decrease in heart rate while on Megtril 1mg Injection. If you experience this symptom, consult your doctor.
Abdominal cramp: Abdominal cramps may occur as a side effect of this medication. If you find this side effect uncomfortable, seek medical advice.
Diarrhea: Diarrhea is another potential side effect of Megtril 1mg Injection. It is important to stay hydrated and notify your doctor if this persists.
High blood pressure: In some cases, Megtril 1mg Injection may lead to high blood pressure. Regular monitoring and consultation with your healthcare provider are recommended.
Peripheral ischemia: This medication may cause peripheral ischemia in some individuals. If you notice symptoms such as cold hands or feet, inform your doctor promptly.
Vasoconstriction of the extremities: Vasoconstriction of the extremities is a possible side effect of Megtril 1mg Injection. Discuss any concerns about this side effect with your healthcare professional.
Remember, it is essential to keep your healthcare provider informed about any side effects you experience while using Megtril 1mg Injection.
Safety advice

liver
Limited information is provided regarding the use of Terlistat Injection in individuals with liver disease. It is crucial to consult your doctor for guidance on the appropriate usage of this medication in such cases.

kidney
There is limited information available on the use of Terlistat Injection in patients with kidney disease. Please consult your doctor.

alcohol
Consult your doctor when consuming alcohol with Terlistat Injection.

driving
When using Terlistat Injection, refrain from driving if you have impairing symptoms affecting focus and reaction time. It is unclear if Terlistat Injection affects driving ability.

pregnancy
Terlistat Injection is not safe to use during pregnancy. It is advised to consult with your doctor as research on both pregnant women and animals has indicated potential harm to the developing baby.

breastfeeding
It is better to consult your doctor before using Terlistat Injection.
Consumption warning before consuming Terlistat Injection
Before taking Terlistat Injection, it's crucial to be aware of some important points. This injection is specifically used to treat bleeding esophageal varices, which are dilated veins in the food pipe leading to the stomach. It works by narrowing blood vessels and reducing blood flow to the affected veins.
Terlistat Injection should only be administered by a healthcare professional and never selfadministered at home. Your doctor will determine the appropriate dosage and frequency based on your condition. This medicine is reserved for patients experiencing severe or lifethreatening bleeding in the esophagus.
Common side effects of Terlistat Injection may include headaches, slow heart rate, high blood pressure, peripheral vasoconstriction, and low blood pressure due to peripheral ischemia. If any of these side effects persist or worsen, inform your doctor promptly.
Prior to using this medication, it's important to disclose any existing heart, liver, or kidney issues to your doctor. Additionally, make sure to inform your doctor about all other medications you are currently taking. Terlistat Injection is not suitable for children or adolescents.
What if you forgot to take Terlistat Injection?
If a dose of Terlistat Injection is missed, it is advisable to skip it and resume with the regular dosing schedule. It is important not to take a double dose to make up for the missed one. Following a missed dose, continue with the next scheduled dose at the usual time to maintain the treatment regimen. If you have concerns or questions about missed doses, consult your healthcare provider for guidance.
Additional Information
Habit Forming | No |
Chemical Class | Vasopressin analogues |
Therapeutic Class | HORMONES |
Action Class | Vasopressin analogues |
FAQs
Disclaimer
The information provided on this website is to the best of our abilities to ensure it is accurate, reliable, and reviewed by a team of professionals. It should not be used to diagnose, prevent, or cure any health problem. The information presented here is not intended to create a doctor-patient relationship or replace a registered medical practitioner's advice, diagnosis, or treatment. The absence or provision of any information or warning regarding any medicine should not be assumed as an implied or explicit assurance of safety or efficacy. We highly recommend consulting your registered medical practitioner for all queries or doubts related to your medical condition. Do not ignore professional medical advice or delay seeking it based on the content encountered on our website. We intend to support, not replace, the doctor-patient relationship.
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Content verified by

Dr. Archana Prabhakar
MBBS, M.Med (Family Medicine)
Last update on 11-Feb-2025