Siropan 1mg Tablet
By Siropan
Rx
10 Tablet in a Strip

Composition
Sirolimus(1mg)

Manufacturer - Panacea Biotec Ltd
Ambala- Chandigarh Highway, Lalru – 140501, Punjab

Expires on or after
July, 2025
About Siropan 1mg Tablet
Siropan 1mg Tablet is a medication used to prevent organ rejection in transplant patients. It works by regulating the body's immune response, allowing it to accept the new organ. It is important to follow the prescribed dose and duration for optimal effectiveness. This tablet can be taken with or without food, but it is recommended to take it at the same time each day to maintain a consistent level in the body. Taking more than the prescribed dose can lead to serious side effects.
Common side effects of Siropan 1mg Tablet include edema, increased blood lipid levels, high blood pressure, elevated creatinine levels, abdominal pain, diarrhea, headache, fever, urinary tract infections, anemia, nausea, joint pain, and thrombocytopenia. If any of these side effects persist or trouble you, it is advised to consult your doctor promptly. Additionally, inform your doctor immediately if you experience any allergic reactions such as rash, shortness of breath, coughing, or swelling.
Before starting the treatment with Siropan 1mg Tablet, consult your doctor, especially if you are taking any other medications for underlying conditions. Pregnant and breastfeeding women should inform their doctor before beginning this treatment. Throughout the course of treatment, your doctor may recommend regular laboratory tests to monitor the effects of the medication on your body. If you notice any signs of infection, changes in moles, unusual growths or lumps, or unusual fatigue while taking Siropan 1mg Tablet, do not hesitate to contact your doctor.
Siropan 1mg Tablet contains Sirolimus, an immunosuppressant that helps prevent the rejection of transplanted organs, particularly kidneys. It is often used in combination with other immunosuppressants like corticosteroids and ciclosporin in the initial months post-transplant. This medication is also prescribed to treat sporadic lymphangioleiomyomatosis (S-LAM) with moderate lung disease, a condition that causes progressive lung issues in women, leading to symptoms like shortness of breath.
During the treatment with Siropan 1mg Tablet, your doctor will conduct tests to monitor drug levels in your blood, kidney function, blood fat levels, and liver function. It is advisable to limit exposure to sunlight and UV light by covering your skin with clothing and using high-protection sunscreen as this medication may increase the risk of skin cancer. Inform your doctor if you have a history of liver problems, elevated BMI, or a failed kidney transplant before starting this treatment. Avoid consuming grapefruit juice while taking Siropan 1mg Tablet. This medication is not recommended for use in pregnant and breastfeeding women, as well as in children and adolescents under 18 years of age. If you experience any worsening or persistent symptoms while on Siropan 1mg Tablet, contact your doctor promptly for further guidance.
Benefits
Siropan 1mg Tablet is a vital medication used in the prevention of kidney transplant rejection. When a person undergoes a kidney transplant, there is a risk of the body rejecting the new organ due to the immune system's attack. This rejection occurs as the immune system sees the transplanted kidney as a foreign object. Siropan 1mg Tablet works by decreasing the activity of the body's immune system, making it less likely to reject the transplanted kidney. By weakening the body's defence system, this medication helps the body accept the new organ as if it belongs there, reducing the chances of rejection and ensuring the success of the kidney transplant. Sirolimus, the key component in Rapasim Tablet 10's, is an immunosuppressant that plays a crucial role in preventing organ rejection in transplanted patients. Taking Siropan 1mg Tablet along with other prescribed medications can significantly improve the outcome of kidney transplant surgeries by assisting the body in accepting the new organ effectively.
How to use the Siropan 1mg Tablet
To use Siropan 1mg Tablet, follow your doctor's instructions on the dose and duration. Swallow the tablet whole with a glass of water. Avoid chewing, crushing, or breaking the tablet. You can take Siropan 1mg Tablet with or without food, but it's best to take it at the same time every day. Your doctor will determine the correct dose and duration based on factors such as your age, weight, and medical condition. It's important to take Siropan 1mg Tablet regularly as prescribed and not to stop unless advised by your doctor. If you have any questions or concerns about how to use Siropan 1mg Tablet, consult your physician for guidance.
Uses of Siropan 1mg Tablet
The Siropan 1mg Tablet is primarily used for the prevention of kidney transplant rejection. It is specifically intended for adults undergoing kidney transplants to help the body accept the new kidney without rejection. This tablet is typically prescribed in conjunction with corticosteroids and initially ciclosporin to effectively manage the transplantation process. Additionally, Siropan 1mg Tablet is also indicated for women diagnosed with sporadic lymphangioleiomyomatosis (S-LAM).
What conditions Siropan 1mg Tablet treats?
Siropan 1mg Tablet is used to prevent organ rejection in patients who have received a transplant. Organ rejection happens when the body's defense system sees the transplanted organ as an invader and attacks it. This medication helps in stopping this reaction, allowing the transplanted organ to function properly.
Should you consult a doctor?
Seek medical attention if you have a body mass index (BMI) greater than 30 kg/m², as this may increase the risk of abnormal wound healing while taking Siropan 1mg Tablet. Additionally, if you have a known intolerance to certain sugars, it is important to consult your doctor before starting this medication to ensure its safety and effectiveness for you. If you experience any unusual or severe symptoms while taking Siropan 1mg Tablet, seek immediate medical advice. Your doctor can provide guidance on the best course of action based on your individual health needs.
Side effects of Siropan 1mg Tablet
Side effects of Siropan 1mg Tablet may vary in severity, and most tend to subside as your body gets used to the medication. Some common side effects include nausea, increased blood lipid levels, low blood platelets, headaches, abdominal pain, fever, anemia, urinary tract infections, diarrhea, high blood pressure, increased creatinine levels in the blood, joint pain, and swelling (edema). More severe side effects may include peripheral edema, high triglyceride levels, hypertension, high cholesterol, increased creatinine, abdominal pain, diarrhea, headaches, fever, urinary tract infections, anemia, nausea, joint pain, and low blood platelets. In rare cases, serious side effects such as cancer of the lymph tissue, lung bleeding, kidney scarring, allergic reactions causing skin peeling, tuberculosis, liver damage, blood clots, skin cancer, pancreas inflammation, and weight loss may occur. It is essential to consult your doctor if any side effects persist or if you experience any severe reactions such as allergic responses or kidney damage while taking Siropan 1mg Tablet.
Safety advice

liver
For individuals with severe liver disease, it is important to use Siropan 1mg Tablet with caution. It may be necessary to adjust the dose of the medication, and consulting your doctor is advised in such cases. However, for those with mild to moderate liver disease, dose adjustment is generally not recommended. If you have concerns or are unsure about using Siropan 1mg Tablet with liver issues, it is best to seek guidance from your healthcare provider.

kidney
Siropan 1mg Tablet is safe for use in patients with kidney disease. No dose adjustment is necessary.

alcohol
It's unclear if it's safe to drink alcohol while taking Siropan 1mg Tablet. Consult your doctor for guidance.

driving
When taking Siropan 1mg Tablet, it is unlikely to impact your driving ability.

pregnancy
Siropan 1mg Tablet may not be safe to use during pregnancy. Animal studies indicate potential harm to the developing baby. Your doctor will assess risks vs. benefits before prescribing. Consult your doctor.

breastfeeding
During breastfeeding, it is not recommended to use Siropan 1mg Tablet as it may pass into the breastmilk and potentially harm the baby. It is advisable to consult a healthcare provider before using this medication while breastfeeding.
Age above 75(Geriatrics)
Age below 6 months(Pediatrics)
Consumption warning before consuming Siropan 1mg Tablet
Before consuming Rapasim Tablet 10's, it is essential to undergo therapeutic drug monitoring. Only use this medication as directed by your doctor to effectively manage your condition. It is crucial not to take Rapasim Tablet 10's without consulting a doctor, especially if you have allergies to it or other medications. If you are pregnant or breastfeeding, make sure to seek advice from your healthcare provider before using Rapasim Tablet 10's. Combining alcohol with this medication can lead to serious adverse reactions, so it is advisable to avoid alcohol consumption while taking Rapasim Tablet 10's. To prevent harmful effects, do not exceed the prescribed dosage or duration of treatment. Prior to starting Rapasim Tablet 10's, inform your doctor about your health status and all medications you are currently taking to prevent any potential side effects.
Disease interactions
Before taking Siropan 1mg Tablet, it is important to inform your doctor about any medical history you may have. This includes allergic reactions to medications, infections, PML (progressive multifocal leukoencephalopathy), angioedema, hyperlipidemia, liver disease, liver transplantation, lung dysfunction, lung transplant, and renal dysfunction. Providing this information is crucial for your doctor to assess the potential interactions between your medical conditions and the medication.
What happens if you take overdose of Siropan 1mg Tablet?
If a person accidentally takes an excessive amount of Siropan 1mg Tablet, it is important to seek immediate medical attention. Consulting a doctor or visiting the nearest hospital is crucial in cases of overdose. It is essential to address the situation promptly to ensure the well-being and safety of the individual who has taken too much of the medication.
Related lab tests
For individuals taking Siropan 1mg Tablet, certain related lab tests are recommended to monitor their health and ensure the medication is safe for them. These tests include blood tests, kidney function tests, and liver function tests. Blood tests help in assessing various components in the blood, such as red blood cells, white blood cells, and platelets, which can provide important information about overall health. Kidney function tests help to evaluate how well the kidneys are working by measuring factors like creatinine and blood urea nitrogen. Liver function tests assess the liver's ability to function properly by checking levels of liver enzymes and other substances in the blood. Regular monitoring of these lab tests can assist healthcare providers in identifying any potential issues early on and adjusting treatment plans accordingly.
Additional Information
Habit Forming | No |
Chemical Class | Macrolide Lactams |
Therapeutic Class | - |
Action Class | Immunosuppressant- mTOR inhibitors |
FAQs
Disclaimer
The information provided on this website is to the best of our abilities to ensure it is accurate, reliable, and reviewed by a team of professionals. It should not be used to diagnose, prevent, or cure any health problem. The information presented here is not intended to create a doctor-patient relationship or replace a registered medical practitioner's advice, diagnosis, or treatment. The absence or provision of any information or warning regarding any medicine should not be assumed as an implied or explicit assurance of safety or efficacy. We highly recommend consulting your registered medical practitioner for all queries or doubts related to your medical condition. Do not ignore professional medical advice or delay seeking it based on the content encountered on our website. We intend to support, not replace, the doctor-patient relationship.
₹2303.95
Inclusive of all taxes
Content verified by

Dr. Upasana Bhatia
MBBS - General Medicine
Last update on 11-Feb-2025