Simulect Injection
By Simulect
Rx
1 Injection in a Vial

Composition
Basiliximab(20mg)

Manufacturer - Novartis India Ltd
Sandoz House, Shiv Sagar Estate, Worli Mumbai -400 018, India

Expires on or after
April, 2026
About Simulect Injection
Simulect Injection is a medication categorized under immunosuppressants, a group of drugs that helps manage the immune system's response to lower the risk of rejection following kidney transplantation. It is typically prescribed alongside other medications for enhanced effectiveness.
It is crucial to note that Simulect Injection is a prescription-only medicine that should be administered exclusively by a healthcare professional. It is imperative to adhere strictly to the prescribed dosage to avoid potential serious side effects associated with overdosing.
Like most medications, Simulect Injection may have common side effects such as nausea, vomiting, and constipation. Additionally, some individuals may experience injection site reactions characterized by redness, pain, or swelling. Notably, this medicine is considered safe for use in pediatric patients.
Before initiating treatment with Simulect Injection, it is essential to inform your healthcare provider about any ongoing medications for underlying conditions. Pregnant or breastfeeding individuals must also notify their doctor before starting this treatment. Throughout the course of treatment, your doctor may recommend periodic laboratory tests to monitor the medication's impact on your body.
By consulting your healthcare provider and adhering to the prescribed guidelines, you can effectively manage the risks and benefits associated with Simulect Injection to support a successful kidney transplantation outcome.
Benefits
Simulect Injection is a medication that is incredibly beneficial in the prevention of kidney transplant rejection. When someone undergoes a kidney transplant, there is a risk of rejection because the recipient's immune system may attack the newly transplanted kidney. By using Simulect Injection along with other medications, doctors can effectively reduce the activity of the patient's immune system, thereby minimizing the chances of rejection. This treatment plays a crucial role in ensuring the success and longevity of kidney transplants by helping the body accept and integrate the new organ without any complications. By preventing rejection, Simulect Injection provides a lifeline for individuals receiving kidney transplants, offering them hope for a healthier future with a fully functioning kidney.
How to use the Simulect Injection
When it comes to using Simulect Injection, it's important to remember that only your doctor or nurse should administer this medicine. It is not safe to try to give yourself this injection. Your healthcare provider will know the correct dosage and the best way to administer the injection. Trust them to take care of this task for you. They have the expertise to ensure that the medicine is delivered safely and effectively into your body. By following this guidance, you can have peace of mind knowing that you are receiving the treatment in the proper way, as intended by your healthcare team.
Uses of Simulect Injection
Simulect Injection is commonly used for preventing kidney transplant rejection. This medication helps in reducing the chances of the body rejecting a newly transplanted kidney, which is crucial for the success of the transplant procedure. By targeting specific immune cells in the body, Simulect Injection works to suppress the immune response that can lead to rejection, allowing the transplanted kidney to function effectively. It is important to follow the prescribed dosage and administration instructions provided by healthcare professionals to achieve the best outcomes in kidney transplant patients.
What conditions Simulect Injection treats?
Simulect Injection is used to help prevent the rejection of kidney transplants. It is classified as an immunosuppressant medicine that works by regulating the immune system. Typically, it is prescribed alongside other medications to reduce the risk of rejection. This prescription medicine should be administered by a healthcare professional following the exact dosage instructions to avoid potential serious side effects. Some common side effects include nausea, vomiting, constipation, and injection site reactions. It can be safely used in children but consultation with a doctor is crucial, especially if there are ongoing medications for other underlying conditions or if one is pregnant or breastfeeding. Monitoring through laboratory tests may be recommended during treatment to assess its effects on the body.
Should you consult a doctor?
If you experience any persistent or concerning side effects while taking Simulect Injection, it is important to seek medical attention. Common side effects like nausea, vomiting, constipation, and injection site reactions may occur. Additionally, if you notice symptoms such as abdominal pain, diarrhea, indigestion, weight gain, headache, pain, swelling of hands, high blood pressure, anemia, or any other unusual reactions, it is recommended to consult your doctor promptly. Inform your healthcare provider if you are pregnant, breastfeeding, or undergoing any other medical treatments. Regular consultation with your doctor during Simulect treatment is crucial to monitor its effects through laboratory tests and ensure the medication is safe and effective for you.
Side effects of Simulect Injection
When using Simulect Injection, some side effects may occur, but most do not need medical attention and usually go away as your body gets used to the medicine. However, if these side effects persist or cause concern, it's important to consult with your doctor. The potential side effects of Simulect Injection include nausea, constipation, abdominal pain, diarrhea, indigestion, vomiting, weight gain, headache, general pain, swelling of the hands, high blood pressure, anemia (low red blood cell count), and injection site reactions such as pain, swelling, and redness. If any of these side effects become bothersome or severe, it is advisable to seek medical advice.
Safety advice

liver
The use of Simulect Injection in patients with liver disease has limited information available. It is important to consult your doctor for proper guidance.

kidney
Limited data suggests no dose adjustment needed for kidney disease patients with Simulect Injection. Consult your doctor for guidance.

alcohol
Consult your doctor when consuming alcohol with Simulect Injection.

driving
When using Simulect Injection, you can normally drive without any problem.

pregnancy
Simulect Injection is believed to be safe for use during pregnancy based on animal studies with minimal adverse effects to the baby. Limited human studies are available.

breastfeeding
It is believed to be safe to use Simulect Injection while breastfeeding. Limited data indicates no significant risk to the baby.
Consumption warning before consuming Simulect Injection
Before consuming Simulect Injection, it is crucial to understand some important points. This medication is classified under immunosuppressants and is primarily used to regulate the immune system for preventing kidney transplant rejection. It is typically prescribed alongside other medications. Since Simulect Injection is a prescription drug, it should only be administered by a healthcare professional following the prescribed dosage. Consuming more than the recommended dose can lead to severe adverse effects on your body.
Some common side effects of this medicine include nausea, vomiting, constipation, and possible injection site reactions like redness, pain, and swelling. It is safe for use in children, but if you are currently on any other medications for underlying conditions, it is crucial to consult your doctor before starting this treatment. Additionally, pregnant or breastfeeding women should inform their healthcare provider before commencing the medication. Throughout the course of treatment, your doctor might recommend regular laboratory tests to monitor the impact of the medication on your body.
Additional Information
Habit Forming | No |
Chemical Class | Monoclonal Antibody |
Therapeutic Class | - |
Action Class | IL-2 Receptor anatgonist |
FAQs
Disclaimer
The information provided on this website is to the best of our abilities to ensure it is accurate, reliable, and reviewed by a team of professionals. It should not be used to diagnose, prevent, or cure any health problem. The information presented here is not intended to create a doctor-patient relationship or replace a registered medical practitioner's advice, diagnosis, or treatment. The absence or provision of any information or warning regarding any medicine should not be assumed as an implied or explicit assurance of safety or efficacy. We highly recommend consulting your registered medical practitioner for all queries or doubts related to your medical condition. Do not ignore professional medical advice or delay seeking it based on the content encountered on our website. We intend to support, not replace, the doctor-patient relationship.
₹76300
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Content verified by

Dr. Gowri Kulkarni
MBBS - General Medicine, DNB - Psychiatry, MRCGP [INT] Family Medicine, BSIC (BACP)
Last update on 11-Feb-2025