Sibofix 400 Tablet

By Sibofix

Rx

10 Tablet in a Strip

Composition icon

Composition

Rifaximin(400mg)

Manufacturer - Dr Reddy's Laboratories Ltd icon

Manufacturer - Dr Reddy's Laboratories Ltd

Dr. Reddy's Laboratories Ltd., 8-2-337, Road No. 3, Banjara Hills, Hyderabad, Telangana 500034, INDIA

Expires on or after icon

Expires on or after

November, 2026

About Sibofix 400 Tablet

Sibofix 400 Tablet is an antibiotic medication primarily used to treat two main conditions: hepatic encephalopathy and infectious diarrhea. Hepatic encephalopathy is a serious condition where the liver fails to remove harmful toxins from the blood, leading to brain damage. This medication also helps in treating infectious traveler's diarrhea caused by E.coli bacteria, and irritable bowel syndrome with diarrhea (IBS-D).

The active ingredient in Sibofix 400 Tablet is 'Rifaximin', which belongs to a group of medicines called 'antibiotics' or 'antibacterials'. Rifaximin works by targeting harmful bacteria in the intestines and preventing the spread of infections caused by the loss of beneficial gut bacteria. By doing this, Sibofix 400 Tablet helps in relieving abdominal pain and diarrhea associated with these conditions.

It is important to take Sibofix 400 Tablet as prescribed by your doctor. The dosage and duration of treatment should be followed strictly to ensure its effectiveness. This medication can be taken with or without food, preferably at the same time each day. It is advised to continue taking Sibofix 400 Tablet for the entire duration prescribed, even if you start feeling better. Stopping the medication early may result in the infection returning and becoming harder to treat.

Like any medication, Sibofix 400 Tablet may cause side effects in some individuals. These side effects can include vomiting, headache, dizziness, nausea, rashes, joint pain, and depression. Most of these side effects are temporary and tend to resolve as the body adjusts to the medication. If you experience persistent or bothersome side effects, it is important to consult your doctor. It is also normal for the color of your urine to change to reddish due to this medicine, which is harmless.

Before starting treatment with Sibofix 400 Tablet, inform your doctor if you are pregnant, breastfeeding, or have any liver, kidney, or heart problems. Additionally, disclose if you have any allergies to antibiotics or any other medications. It is crucial to follow your doctor's advice and inform them about your health condition to minimize the risk of any adverse reactions.


Benefits

Sibofix 400 Tablet offers several benefits in the treatment of specific conditions. Firstly, in cases of hepatic encephalopathy, a serious liver disease affecting brain function, this medication works by reducing the levels of ammonia-producing bacteria in the blood. By targeting these harmful bacteria that affect the brain, Sibofix 400 Tablet can help to improve brain function and alleviate symptoms such as confusion, tremors, sleep disturbances, and even loss of consciousness associated with hepatic encephalopathy. By taking this medication as directed, patients may experience a significant improvement in their condition.


Furthermore, Sibofix 400 Tablet is also effective in the treatment of infectious diarrhea, a condition characterized by the sudden onset of loose or watery stools due to harmful microorganisms in the digestive system. This medication targets and inhibits the growth of these harmful bacteria in the intestines, disrupting their ability to produce essential proteins necessary for survival and multiplication. By effectively eliminating the bad bacteria causing the infection, Sibofix 400 Tablet helps to reduce the severity and duration of infectious diarrhea, ultimately leading to symptom relief and promoting a faster recovery process for individuals suffering from this condition.


In summary, Sibofix 400 Tablet provides significant benefits in the management of hepatic encephalopathy and infectious diarrhea by addressing the underlying causes of these conditions and helping to improve patient outcomes through its targeted action on harmful bacteria in the body.


How to use the Sibofix 400 Tablet

To properly use Sibofix 400 Tablet, follow your doctor's instructions on dosage and duration of treatment. Swallow the tablet whole, without chewing, crushing, or breaking it. You can take Sibofix 400 Tablet with or without food, but try to take it at the same time every day for better results. Following these guidelines will ensure you get the most out of your medication and help you manage your condition effectively. Always consult your doctor if you have any questions or concerns about how to use Sibofix 400 Tablet.


Uses of Sibofix 400 Tablet

Sibofix 400 Tablet is commonly used for treating Hepatic encephalopathy, a condition where the liver is unable to properly remove toxins, leading to brain function impairment. This medication is also effective in treating Infectious diarrhea, a gastrointestinal condition caused by various pathogens such as bacteria, viruses, or parasites. By targeting the underlying causes of these conditions, Sibofix 400 Tablet helps to alleviate symptoms and improve overall health.


What conditions Sibofix 400 Tablet treats?

Sibofix 400 Tablet is used to treat hepatic encephalopathy, a liver condition that can lead to brain damage due to an inability to remove harmful toxins from the blood. It also helps with infectious diarrhea by killing and inhibiting the growth of harmful bacteria in the intestines. This medication can improve brain function and reduce symptoms of hepatic encephalopathy. For infectious diarrhea, Sibofix 400 Tablet targets the harmful bacteria, helping to alleviate symptoms by stopping their growth in the intestines.


Should you consult a doctor?

If you experience persistent side effects such as vomiting, headache, dizziness, nausea, rashes, joint pain, or depression while taking Sibofix 400 Tablet, it is advisable to consult your doctor. Additionally, if you notice reddish-colored urine, there is no need to worry as this is a harmless side effect of the medication. However, if any of these side effects become bothersome or do not go away as your treatment progresses, seeking medical advice is recommended. Furthermore, before starting treatment with this antibiotic, inform your doctor if you are pregnant, breastfeeding, or have any existing liver, kidney, or heart issues, or if you have any allergies to medications. Adhering to the prescribed dose and duration of treatment is essential to prevent the recurrence of infections that could be harder to manage. Remember, your doctor is there to help address any concerns you may have during your course of treatment.


Side effects of Sibofix 400 Tablet

When taking Sibofix 400 Tablet, some individuals may experience side effects. These side effects are usually mild and temporary as your body gets used to the medication. Common side effects include dizziness, nausea, peripheral edema (swelling in lower limbs), ascites (fluid buildup in the abdominal cavity), fatigue, depression, nasopharyngitis (inflammation of throat and nasal passages), joint pain, rash, and muscle pain. It is important to note that these side effects typically do not require medical intervention and may resolve on their own. However, if any of these side effects persist or cause concern, it is advisable to consult with your doctor for further guidance.


Safety advice

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liver

It is important to be cautious when using Sibofix 400 Tablet in patients with severe liver disease. Adjusting the dose of Sibofix 400 Tablet may be necessary in such cases. It is recommended to consult your doctor before using this medication if you have liver issues.

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kidney

Sibofix 400 Tablet is considered safe for use in patients with kidney disease. Available data suggests no dose adjustment may be necessary. Please consult your doctor.

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alcohol

Consult your doctor when consuming alcohol with Sibofix 400 Tablet.

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driving

Sibofix 400 Tablet does not typically impact your driving ability. Drive safely.

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pregnancy

Sibofix 400 Tablet may not be safe during pregnancy as animal studies have shown harmful effects on the developing baby. Your doctor will assess the benefits and risks before prescribing it to you. Please consult your doctor before using.

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breastfeeding

Sibofix 400 Tablet is likely safe to use during breastfeeding. Limited human data indicates no notable risk to the baby.


Consumption warning before consuming Sibofix 400 Tablet

Before consuming Sibofix 400 Tablet, it is important to take note of a few key warnings. This antibiotic is primarily used to combat hepatic encephalopathy, a serious liver-related condition that affects toxin removal and can cause brain damage, as well as to treat infectious diarrhea. It functions by eradicating harmful bacteria in the intestines. This medication can be taken alone or in conjunction with other medications, with or without food, ideally at the same time daily, as prescribed by your healthcare provider.

To derive the most benefit, take the tablet consistently at the prescribed time each day for the recommended duration. Abruptly discontinuing the medication may result in the infection resurfacing and becoming more challenging to treat. Some commonly reported side effects include vomiting, headache, dizziness, nausea, rashes, joint pain, and transient depression, which typically improve over the course of treatment as your body adapts. In the event that these side effects persist or are bothersome, it is advisable to consult your doctor promptly. A harmless side effect to note is that the medication may cause your urine to appear reddish in color.

Before commencing treatment with Sibofix 400 Tablet, inform your doctor if you are pregnant, breastfeeding, have liver, kidney, or heart issues, or are allergic to any medications.


What if you forgot to take Sibofix 400 Tablet?

If you forget to take a dose of Sibofix 400 Tablet, try to take it as soon as you remember. But if it's almost time for your next scheduled dose, then it's best to skip the missed one and continue with your regular dosing schedule. Avoid doubling up on doses to make up for the missed one.


Related lab tests

Related Lab Tests:


When taking Sibofix 400 Tablet, it is important to monitor certain lab tests to ensure the medication is working effectively and that your body is responding well. The following are the related lab tests that may be recommended by your healthcare provider:


1. Liver Function Test: This test is done to assess how well your liver is functioning, as Sibofix 400 Tablet may have an impact on liver enzymes.


2. Potassium and Sodium Levels: These tests are important to check the balance of electrolytes in your body, as changes in these levels can affect various bodily functions.


3. Ammonia Levels: Monitoring ammonia levels is crucial as high levels can indicate liver or kidney problems, which may be influenced by taking Sibofix 400 Tablet.


4. Stool Examination (R/M) and Culture Stool: These tests are done to check for any presence of infection or abnormalities in the digestive system, which can be important while on this medication.


It is advisable to consult with your healthcare provider to determine the specific lab tests that are appropriate for you based on your individual health condition and medical history. Regular monitoring of these lab tests can help in ensuring your safety and well-being while taking Sibofix 400 Tablet.


Additional Information

Habit FormingNo
Chemical ClassRifamycin derivatives
Therapeutic ClassGASTRO INTESTINAL
Action ClassRNA polymerase inhibitors- Rifamycins

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Disclaimer

The information provided on this website is to the best of our abilities to ensure it is accurate, reliable, and reviewed by a team of professionals. It should not be used to diagnose, prevent, or cure any health problem. The information presented here is not intended to create a doctor-patient relationship or replace a registered medical practitioner's advice, diagnosis, or treatment. The absence or provision of any information or warning regarding any medicine should not be assumed as an implied or explicit assurance of safety or efficacy. We highly recommend consulting your registered medical practitioner for all queries or doubts related to your medical condition. Do not ignore professional medical advice or delay seeking it based on the content encountered on our website. We intend to support, not replace, the doctor-patient relationship.

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Dr. Upasana Bhatia

MBBS - General Medicine

Last update on 01-Oct-2024