Regonat Tablet

By Regonat

Rx

28 Tablet in a Bottle

Composition icon

Composition

Regorafenib(40mg)

Manufacturer - Natco Pharma Ltd icon

Manufacturer - Natco Pharma Ltd

Natco House, Road No.2, Banjara Hills, Hyderabad-500 034, India

Expires on or after icon

Expires on or after

January, 2026

About Regonat Tablet

Regonat Tablet is a type of medication known as a Tyrosine kinase inhibitor. It is commonly used in the treatment of colorectal cancer, which is a type of cancer that affects the colon and rectum. When taking Regonat Tablet, it is important to ensure that it is consumed with food, ideally at the same time each day to maximize its effectiveness. The dosage and frequency of taking the medication will be determined by your doctor based on your specific condition and may be subject to adjustments over time. It is crucial to strictly adhere to the doctor's instructions regarding the administration of the medication to avoid potential serious side effects.

Like any medication, Regonat Tablet may cause certain side effects, although not everyone may experience them. Common side effects of this medicine include infections, lowered blood platelet count, anemia, reduced appetite, bleeding tendencies, and elevated blood pressure. Other possible side effects may involve changes in voice, diarrhea, mouth sores, vomiting, nausea, presence of bilirubin in urine, elevated liver enzymes, skin rash, weakness, pain, fever, inflammation of mucous membranes, and weight loss. Should you experience any of these side effects, it is advisable to promptly inform your doctor. Regular blood tests are necessary to monitor your blood cell count and liver function while on this medication.

It is important to note that Regonat Tablet can interact with other medications, potentially affecting their efficacy or causing adverse reactions. Therefore, it is essential to inform your healthcare provider about all the drugs you are currently using before starting Regonat Tablet. This medicine is not recommended for use during pregnancy or breastfeeding due to potential risks to the developing fetus or infant. Both males and females undergoing treatment should use effective contraception to prevent pregnancy.

Regonat 40 mg Tablet 28's, which contains Regorafenib as its active ingredient, is a specific formulation used in the treatment of colorectal carcinoma. Colorectal cancer is characterized by the uncontrolled growth of cancerous or malignant cells in the colon or rectum. Regonat 40 mg Tablet 28's operates as a kinase inhibitor by targeting and inhibiting the activity of an enzyme known as tyrosine kinase, consequently arresting the abnormal growth of cancer cells.

Individuals who are allergic to Regonat 40 mg Tablet 28's or any of its components should refrain from its use. Prior to commencing treatment with this medication, it is important to disclose to your doctor any history of liver or kidney disease, gastrointestinal issues, hypertension, cardiac conditions, blood disorders, intentions of undergoing surgery, or any skin disorders. Pregnant women and breastfeeding mothers are advised against using this medication due to potential risks of harm to the unborn child or nursing infant.


Benefits

The Regonat Tablet, containing Regorafenib, offers several benefits in the treatment of colorectal cancer (CRC). This medication is specifically used for patients who have previously undergone fluoropyrimidine-, oxaliplatin- and irinotecan-based chemotherapy, antiVEGF therapy, and possibly anti-EGFR therapy if they have KRAS wild type. Regonat Tablet works by targeting and stopping the action of a tyrosine kinase enzyme responsible for the multiplication of cancer cells. By inhibiting this enzyme, it effectively halts the abnormal growth of cancer cells, reducing the risk of further spread to other parts of the body.

One of the key benefits of Regonat Tablet is its ability to treat existing cancerous growths and lower the risk of developing additional cancerous growths, such as polyps, in the colon and rectum. Moreover, this medication is known for its efficacy in killing or inhibiting the growth of cancer cells, thereby preventing their multiplication and spread. By effectively targeting these cancer cells, Regonat Tablet plays a crucial role in impeding the body's production, spread, and growth of cancer cells associated with colorectal cancer.

However, it is essential to note that Regonat Tablet is a potent and potentially toxic medicine. Therefore, it is imperative to consult with a healthcare professional to discuss the associated risks and benefits before initiating treatment. Additionally, individuals undergoing treatment with Regonat Tablet should avoid alcohol and smoking to optimize the medication's efficacy. Staying hydrated by consuming an adequate amount of water is also crucial during the treatment with this medication.

In conclusion, Regonat Tablet, with its active component Regorafenib, offers significant benefits in the management of colorectal cancer by targeting cancerous cells and hindering their growth and spread. By understanding its mechanism of action and consulting with healthcare providers, patients can maximize the therapeutic benefits of Regonat Tablet in their cancer treatment regimen.


How to use the Regonat Tablet

When using Regonat Tablet, it is essential to follow your doctor's instructions carefully. Take the prescribed dose of Regonat Tablet with food as advised by your doctor. It is important to swallow the tablet whole with a glass of water and not chew, crush, or break it. Typically, NUBLEXA 40MG TABLET 28'S should be taken once daily for 21 days, followed by a break of 7 days. This cycle constitutes one round of therapy. Repeat this cycle as recommended by your doctor. It is crucial not to exceed the prescribed dose of the medicine. Remember to take Regonat Tablet consistently and seek guidance from your healthcare provider if you have any concerns.


Uses of Regonat Tablet

Regonat Tablet is used in the treatment of colorectal cancer, which specifically involves cancer of the colon and rectum. This medication is prescribed to help patients battle this type of cancer.


What conditions Regonat Tablet treats?

Regonat Tablet is used to treat colorectal cancer, a condition where cancer cells grow uncontrollably in the colon or rectum. Symptoms include diarrhoea, constipation, bloody stools, changes in bowel habits, and abdominal discomfort.


Should you consult a doctor?

If you experience any side effects such as infection, low blood platelets, anemia, rash, weakness, vomiting, pain, nausea, fever, diarrhea, high blood pressure, decreased appetite, mucosal inflammation, stomatitis, increased liver enzymes, weight loss, voice change, or bilirubin in urine while taking Regonat Tablet, it is important to inform your doctor. Regular blood tests are necessary to monitor your blood cells and liver function. If you are concerned about persistent side effects, consult your healthcare provider. It is crucial to communicate all medications you are taking to your healthcare team as interactions can occur. Avoid using this medicine during pregnancy or while breastfeeding, and use effective contraception during treatment to prevent pregnancy. Stick to the prescribed dosage and timing advised by your doctor to maximize benefits and minimize the risk of serious side effects.


Side effects of Regonat Tablet

When taking Nublexa Tablets, some individuals may experience side effects, although most of these effects do not typically necessitate medical attention and tend to diminish as the body adapts to the medication. It is advisable to consult with your doctor if any of these side effects persist or if you have concerns about them. Potential side effects may include infections, low blood platelets, anemia (a low number of red blood cells), skin rash, weakness, vomiting, pain, nausea, fever, diarrhea, high blood pressure, decreased appetite, mucosal inflammation, stomatitis (inflammation of the mouth), tiredness, chest pain, dizziness, increased liver enzymes, weight loss, voice change, and the presence of bilirubin in urine. Specific symptoms such as nausea, diarrhea, loss of appetite, skin rash, hoarseness, tiredness, chest pain, dizziness, and weakness may also occur.


Safety advice

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liver

When using Regonat Tablet, it is important to be cautious if you have liver disease. Patients with liver issues may require a dose adjustment, so it's vital to consult your doctor before starting this medication. Regular monitoring of liver function tests is recommended while taking Regonat Tablet to ensure your liver health is maintained. Patients with severe liver disease are advised against using Regonat Tablet. If you have any concerns regarding your liver health, make sure to seek guidance from your healthcare provider.

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kidney

Regonat Tablet is considered safe for use in patients with kidney disease. No dose adjustment is necessary. However, there is limited information on its use in patients with severe kidney disease.

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alcohol

Consult your doctor when consuming alcohol with Regonat Tablet.

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driving

When taking Regonat Tablet, avoid driving if you notice any symptoms that may impact your focus and reaction time. It's uncertain if Regonat Tablet affects driving ability.

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pregnancy

Regonat Tablet should not be used during pregnancy due to the known risk to the developing baby. Only in life-threatening situations, a doctor may consider prescribing it if benefits outweigh risks. Always consult your doctor.

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breastfeeding

Caution is advised when using Regonat Tablet while breastfeeding as it may be unsafe. Limited data suggests the drug could pass into breastmilk, potentially harming the baby.


Consumption warning before consuming Regonat Tablet

Before consuming Nublexa 40mg Tablet 28's, please be aware of the following precautions. Do not take this medicine if you have allergies to it or any of its ingredients. Nursing mothers should stop breastfeeding while on this medication as it can pass into breast milk and pose risks to the infant. It is not suitable for children under 18 years old due to unknown safety and efficacy. Potential side effects may include hypertension, heart attack, skin reactions, gastrointestinal issues, bleeding, liver problems, and Reversible Posterior Leukoencephalopathy Syndrome (RPLS). It is crucial to disclose your full medical history and current medications to the doctor before starting this treatment. If you are pregnant or planning to become pregnant, consult your doctor as this medicine can harm the developing fetus. Additionally, be cautious while driving or operating machinery as Nublexa may cause dizziness.


Related lab tests

Related Lab Tests:
When taking Regonat Tablet, it is important to monitor certain lab tests to help manage your health. One of the key lab tests to consider is the Carcino Embryonic Antigen (CEA) test. This test measures the levels of CEA in the blood, which is a protein that may be elevated in certain types of cancer, such as colorectal cancer. Monitoring CEA levels can help track the progress of cancer treatment and detect any recurrence. Additionally, other relevant lab tests to consider while on Regonat Tablet may include liver function tests, complete blood count (CBC), and any other tests recommended by your healthcare provider. Regular monitoring of these lab tests can provide valuable information about your health status and help ensure the effectiveness and safety of Regonat Tablet treatment.


Additional Information

Habit FormingNo
Chemical ClassDiarylethers Derivative
Therapeutic Class-
Action ClassTyrosine kinase inhibitors

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Disclaimer

The information provided on this website is to the best of our abilities to ensure it is accurate, reliable, and reviewed by a team of professionals. It should not be used to diagnose, prevent, or cure any health problem. The information presented here is not intended to create a doctor-patient relationship or replace a registered medical practitioner's advice, diagnosis, or treatment. The absence or provision of any information or warning regarding any medicine should not be assumed as an implied or explicit assurance of safety or efficacy. We highly recommend consulting your registered medical practitioner for all queries or doubts related to your medical condition. Do not ignore professional medical advice or delay seeking it based on the content encountered on our website. We intend to support, not replace, the doctor-patient relationship.

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Dr. Gowri Kulkarni

MBBS - General Medicine, DNB - Psychiatry, MRCGP [INT] Family Medicine, BSIC (BACP)

Last update on 11-Feb-2025