Pentanerv-NT 100mg/10mg Tablet

By Pentanerv-NT

Rx

10 Tablet in a Strip

Composition icon

Composition

Gabapentin(100mg) + Nortriptyline(10mg)

Manufacturer - Alkem Laboratories Ltd icon

Manufacturer - Alkem Laboratories Ltd

Alkem Laboratories Limited, Devashish Building, Alkem House, Senapati Bapat Road, Lower Parel, Mumbai - 400 013.

Expires on or after icon

Expires on or after

October, 2025

About Pentanerv-NT 100mg/10mg Tablet

Pentanerv-NT 100mg/10mg Tablet is a medication specifically designed to manage neuropathic pain, which is characterized by pain originating from nerve damage. By acting on the pain signals that travel to the brain, this medicine effectively reduces the sensation of pain, providing relief to individuals experiencing neuropathic pain.

This tablet is intended to be taken orally, either with or without food, and ideally in the evening or at night. It is recommended to adhere to a consistent daily schedule for taking Pentanerv-NT 100mg/10mg Tablet in order to ensure a steady level of the medication in the bloodstream. In the event of a missed dose, it is advisable to take it as soon as possible. Completing the full course of treatment is crucial even if symptoms improve, as discontinuing the medication abruptly without consulting a healthcare provider can potentially exacerbate symptoms.

While using Pentanerv-NT 100mg/10mg Tablet, some common side effects may occur, such as constipation, difficulty in urination, weight gain, fatigue, and dry mouth. Additionally, dizziness and drowsiness can manifest, warranting precaution in activities like driving or tasks that demand mental acuity until the individual understands the effects of the medicine. To address the potential weight gain associated with this medication, engaging in regular physical activity and maintaining a balanced diet is recommended. It is imperative to promptly report any unusual changes in mood to a doctor, as Pentanerv-NT 100mg/10mg Tablet has the potential to cause alterations in mood that may lead to suicidal thoughts.

Prior to initiating treatment with Pentanerv-NT 100mg/10mg Tablet, it is essential to inform your healthcare provider if you have a history of kidney or liver disease. Disclose all other medications you are currently taking, as they may interact with Pentanerv-NT and affect its efficacy or mechanism of action. For individuals who are pregnant, planning pregnancy, or breastfeeding, consulting a doctor before commencing this medication is strongly advised to ensure the safety of both the individual and the unborn child.


Benefits

Pentanerv-NT 100mg/10mg Tablet offers several benefits in the treatment of neuropathic pain. This medication is specifically designed to alleviate long-lasting pain that originates from nerve damage caused by conditions such as diabetes, shingles, or spinal cord injury. By combining Gabapentin and Nortriptyline, Pentanerv-NT 100mg/10mg Tablet effectively reduces pain and its associated symptoms like mood changes, sleep disturbances, and fatigue. Gabapentin, an anti-convulsant, acts by binding to specific sites on voltage-gated calcium channels, which not only helps in relieving nerve pain but also reduces the risk of seizures. On the other hand, Nortriptyline, a tricyclic antidepressant, works by prolonging the effects of serotonin and noradrenaline in the brain. By preventing the reabsorption of these chemical messengers back into the nerve cells, Nortriptyline disrupts the movement of pain signals in the brain, providing further relief from neuropathic pain. Overall, Pentanerv-NT 100mg/10mg Tablet's mechanism of action interferes with pain signals traveling through damaged nerves and the brain, offering significant relief and improving the quality of life for individuals suffering from neuropathic pain.


How to use the Pentanerv-NT 100mg/10mg Tablet

To use Pentanerv-NT 100mg/10mg Tablet, follow your doctor's guidance on the dose and duration. It is essential to swallow the tablet whole without chewing, crushing, or breaking it. You can take Pentanerv-NT 100mg/10mg Tablet with or without food, but it is recommended to take it at the same time each day. When taking the tablet, make sure to have a glass of water to help with swallowing. Your doctor will determine the right dosage and duration based on factors such as your age, weight, and medical condition. It is important to strictly adhere to your doctor's instructions to ensure the effectiveness of the medication.


Uses of Pentanerv-NT 100mg/10mg Tablet

Pentanerv-NT 100mg/10mg Tablet is commonly used to treat neuropathic pain in adults. Neuropathic pain refers to a type of pain that occurs due to nerve damage or dysfunction. This medication is specifically designed to help manage the symptoms of neuropathic pain and improve the overall quality of life for individuals experiencing this type of discomfort. By targeting the underlying causes of neuropathic pain, Pentanerv-NT 100mg/10mg Tablet aims to provide relief and alleviate the associated symptoms. It is a trusted option for those seeking effective treatment for neuropathic pain.


What conditions Pentanerv-NT 100mg/10mg Tablet treats?

Neuropathic pain is a chronic nerve disease resulting from sensory nerve damage. It may present as prickling, stabbing, tingling, or burning sensations. Symptoms include spontaneous pain, unpleasant sensations, difficulty sleeping, and evoked pain. Unlike typical pain signaling from injuries, neuropathic pain occurs without specific triggers. Numbness and loss of sensation are also common in this condition.


Should you consult a doctor?

Seek immediate medical advice if you experience symptoms of mania while taking Pentanerv-NT 100mg/10mg Tablet. It is crucial to inform your healthcare provider before starting this medication if you have nervous system or respiratory disorders, suicidal thoughts, schizophrenia, bipolar disorder, thyroid conditions, epilepsy history, glaucoma, enlarged prostate, diabetes, urination difficulties, blocked intestine or gastric outlet narrowing, hyperpyrexia, or are undergoing electroconvulsive therapy. If you encounter any concerning side effects or worsening of your condition while on Pentanerv-NT 100mg/10mg Tablet, do not hesitate to seek medical attention promptly. Your doctor will be able to provide guidance and determine the best course of action based on your individual health needs.


Side effects of Pentanerv-NT 100mg/10mg Tablet

When taking Pentanerv-NT 100mg/10mg Tablet, some side effects may occur as your body gets used to the medication. These side effects are usually mild and may go away on their own. However, if any of the following side effects persist or concern you, it is important to consult with your doctor. Side effects may include tiredness, orthostatic hypotension (sudden drop in blood pressure when standing up), increased heart rate, uncoordinated body movements, constipation, difficulty in urination, weight gain, sleepiness, dizziness, blurred vision, dry mouth, decreased white blood cell count, peripheral edema, weakness, impotence, indigestion, and insomnia. Other potential side effects include swelling in limbs, face, and trunk, abnormal liver function test results, mental impairment, increased blood glucose levels, changes in sleep patterns, increased breast milk production, excessive sweating, tremors, irregular heartbeat, weight gain, aggression, flushing, fatigue, confusion, prolonged QT interval in the heart, changes in taste, decreased libido, tingling in arms and legs, urinary problems, thirst, low sodium levels, viral infections, and high blood pressure. Severe side effects that require immediate medical attention include muscle pain or weakness, acute pancreatitis, allergic reactions such as swelling of lips, tongue, and face, skin rash, hair loss, hives, fever, swollen glands, yellowing of skin or eyes, unusual bleeding, severe fatigue, and breathing difficulties. If any of these serious side effects occur, stop taking the medication and contact your physician immediately.


Safety advice

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liver

When using Pentanerv-NT 100mg/10mg Tablet, it is important to be cautious if you have liver disease. Your doctor may need to adjust the dose accordingly, so it is essential to consult them before taking this medication. If you experience any signs or symptoms of jaundice while on Pentanerv-NT 100mg/10mg Tablet, inform your doctor immediately. It is advised not to use this medicine in patients with severe liver disease.

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kidney

Pentanerv-NT 100mg/10mg Tablet needs caution in kidney disease patients. Dosage adjustment may be required, so consult your doctor.

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alcohol

Pentanerv-NT 100mg/10mg Tablet can increase drowsiness when taken with alcohol.

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driving

Caution Pentanerv-NT 100mg/10mg Tablet may impact alertness and driving ability due to potential side effects.

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pregnancy

Pentanerv-NT 100mg/10mg Tablet may not be safe to use during pregnancy. Animal studies have shown potential harm to the developing baby. Your doctor will assess the benefits and risks before prescribing this medication. It is important to consult your doctor regarding its use during pregnancy.

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breastfeeding

Pentanerv-NT 100mg/10mg Tablet may not be safe to use while breastfeeding. Limited evidence indicates the drug can enter breastmilk and potentially harm the baby.


Age above 75(Geriatrics)

Pentanerv-NT 100mg/10mg Tablet should be used with caution in elderly patients (above 65 years of age). Consult your doctor before taking Pentanerv-NT 100mg/10mg Tablet.


Age below 6 months(Pediatrics)

Pentanerv-NT 100mg/10mg Tablet is generally not recommended for use in children and adolescents (under 18 years of age). Consult your doctor before taking.


Consumption warning before consuming Pentanerv-NT 100mg/10mg Tablet

Before consuming Pentanerv-NT 100mg/10mg Tablet, make sure you are not allergic to any of its components. Inform your doctor if you have a history of heart problems or bipolar syndrome. If you are pregnant or breastfeeding, consult your doctor before taking this medication. Be cautious as Pentanerv-NT 100mg/10mg Tablet may cause drowsiness and dizziness, so avoid driving or operating machinery if you feel sleepy. It is advisable to refrain from alcohol consumption while on this medication to prevent amplified dizziness and drowsiness. Keep your doctor updated on your health condition and other medications to avoid potential side effects.


Disease interactions

When taking Pentanerv-NT 100mg/10mg Tablet, it is important to inform your doctor about any pre-existing medical conditions you may have. This includes heart problems, pheochromocytoma, depression, seizures, bone marrow suppression, diabetes, schizophrenia, bipolar disorder, glaucoma, thyroid problems, suicidal tendency, haemodialysis, as well as kidney and liver problems. By disclosing this information to your healthcare provider, they can determine if Pentanerv-NT 100mg/10mg Tablet is suitable for you based on your individual health circumstances. This ensures the medication's effectiveness and helps prevent any potential drug interactions that could arise from your specific medical history.


What if you forgot to take Pentanerv-NT 100mg/10mg Tablet?

If you forget to take a dose of Pentanerv-NT 100mg/10mg Tablet, take it as soon as you remember. But if it is close to the time for your next dose, just skip the missed one and continue with your usual dosing schedule. Avoid taking a double dose to make up for the missed one. It's important to be consistent with your medication schedule to ensure the effectiveness of the treatment.


What happens if you take overdose of Pentanerv-NT 100mg/10mg Tablet?

In case of accidentally taking too much Pentanerv-NT 100mg/10mg Tablet, it is important to seek help promptly. Symptoms of an overdose can vary and may include blurred vision, fast or irregular heartbeats, difficulty passing urine, dry mouth, intestinal blockage, seizures, fever, agitation, confusion, hallucinations, uncontrolled movements, low blood pressure, weak pulse, pallor, breathing difficulties, blue skin discoloration, and decreased heart rate. Seek immediate medical assistance by contacting your doctor or visiting the nearest hospital if you suspect an overdose.


Additional Information

Habit FormingNo
Chemical Class-
Therapeutic ClassNEURO CNS
Action Class-

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Disclaimer

The information provided on this website is to the best of our abilities to ensure it is accurate, reliable, and reviewed by a team of professionals. It should not be used to diagnose, prevent, or cure any health problem. The information presented here is not intended to create a doctor-patient relationship or replace a registered medical practitioner's advice, diagnosis, or treatment. The absence or provision of any information or warning regarding any medicine should not be assumed as an implied or explicit assurance of safety or efficacy. We highly recommend consulting your registered medical practitioner for all queries or doubts related to your medical condition. Do not ignore professional medical advice or delay seeking it based on the content encountered on our website. We intend to support, not replace, the doctor-patient relationship.

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Dr. Abdullah Khan

MBBS - General Medicine

Last update on 18-Nov-2024