Pemnat 100mg Injection

By Pemnat

Rx

1 Injection in a Vial

Composition icon

Composition

Pemetrexed(100mg)

Manufacturer - Natco Pharma Ltd icon

Manufacturer - Natco Pharma Ltd

Natco House, Road No.2, Banjara Hills, Hyderabad-500 034, India

Expires on or after icon

Expires on or after

April, 2026

About Pemnat 100mg Injection

Pemnat 100mg Injection is a medication used in the treatment of non-small cell lung cancer and malignant pleural mesothelioma. It contains Pemetrexed, which is categorized as an Anticancer agent. This injection is administered by a qualified medical professional, and your doctor will determine the appropriate dosage and frequency based on your condition. It is crucial to follow your doctor's instructions carefully to avoid serious side effects.

Patients may not experience immediate benefits from Pemnat 100mg Injection, as it might take several weeks or months for the effects to become noticeable. It is essential to continue taking the medication as prescribed unless otherwise instructed by your doctor. Common side effects of this medicine include nausea, vomiting, loss of appetite, and hair loss. Additionally, it may lower the number of blood cells, making you more prone to infections. Regular blood tests are necessary to monitor your blood cell count, as well as heart, liver, and blood uric acid levels.

Before starting treatment with Pemnat 100mg Injection, inform your doctor if you have any underlying heart disease, liver or kidney issues, or if you are taking medications for infections. It is important to disclose all medicines you are currently using, as there may be interactions with Pemnat 100mg Injection. This medicine is not recommended for use during pregnancy or while breastfeeding. Both men and women undergoing therapy with Pemnat 100mg Injection must use effective contraception to prevent pregnancy.

Pemnat 100mg Injection is specifically designed to treat advanced stages of non-small cell lung cancer and malignant pleural mesothelioma. In cases where patients have not responded well to conventional treatments, this medication can be an effective alternative. It is often used in combination with other anti-cancer medicines, such as cisplatin or carboplatin, to enhance its efficacy.

Prior to receiving Pemnat 100mg Injection, ensure your doctor is aware of any lung, liver, kidney, or heart conditions you may have, as well as any history of fluid accumulation in the lungs or recent radiation therapy. It is crucial to report any upcoming radiation therapy or vaccinations to your healthcare provider as a precautionary measure.

If you experience any side effects such as increased infections, sore throat, nausea, vomiting, stomach pain, dizziness, tiredness, weight loss, changes in taste, skin rash, hair loss, or mouth ulcers, contact your doctor promptly. Monitoring and addressing these side effects can help ensure the effectiveness of the treatment with Pemnat 100mg Injection.


Benefits

Pemnat 100mg Injection offers significant benefits in the treatment of two types of cancer: non-small cell lung cancer and malignant pleural mesothelioma. For non-small cell lung cancer, which is a major type of lung cancer that affects both smokers and non-smokers, this medication can be used either on its own or in combination with other treatments. It is a strong and potentially harmful medicine, so it is crucial to have a detailed discussion with your doctor about the risks and advantages of the treatment. While undergoing this treatment, it is advised to avoid alcohol consumption and ensure proper hydration by drinking sufficient water.

In the case of malignant pleural mesothelioma, a highly aggressive form of lung cancer that develops in the lungs and the inner side of the ribs, Pemnat 100mg Injection is employed in combination with other medications to combat the disease. The injection works by targeting and destroying cancer cells, preventing their further growth and spread to other parts of the body. To maximize the benefits of this treatment, it is essential to strictly adhere to your doctor's guidance and promptly address any concerns or queries you may have.

Overall, Pemnat 100mg Injection demonstrates promising outcomes in the management of non-small cell lung cancer and malignant pleural mesothelioma by effectively combating cancer cells and impeding their progression. Consulting with your doctor and following their recommendations diligently can help optimize the therapeutic benefits of this medication in your cancer treatment regimen.


How to use the Pemnat 100mg Injection

To use Pemnat 100mg Injection, you should always remember that it must be administered by a doctor or a nurse. This particular medication is given directly into a vein as an intravenous infusion. It's crucial not to attempt to administer it to yourself. Your doctor will carefully determine the right dosage and duration of treatment tailored specifically for you. This assessment will take into account factors such as your age, body weight, and the specific disease or condition being treated. By following these instructions and allowing a healthcare professional to administer Pemnat 100mg Injection, you are ensuring the safest and most effective use of this medication for your health needs.


Uses of Pemnat 100mg Injection

Pemnat 100mg Injection is used to treat advanced non-small cell lung cancer (NSCLC) and malignant pleural mesothelioma, which is a type of cancer affecting the protective layer of the lungs. It is specifically designed to help patients suffering from these conditions by targeting the cancer cells and helping to slow down the progression of the diseases. By administering Pemnat 100mg Injection as prescribed by a healthcare professional, patients can benefit from its therapeutic effects in managing the symptoms and improving their overall quality of life.


What conditions Pemnat 100mg Injection treats?

Pemnat 100mg Injection is prescribed for treating non-small cell lung cancer and malignant pleural mesothelioma. Non-small cell lung cancer affects smokers and non-smokers and requires discussion of risks and benefits with your doctor. Avoid alcohol and stay hydrated during treatment. Malignant pleural mesothelioma, a aggressive lung cancer, is treated with Pemnat 100mg Injection to kill cancer cells and prevent further spread. Follow doctor's instructions closely and seek clarifications when needed. Regular blood tests are necessary due to potential side effects like decreased blood cells. Effective contraception must be used to prevent pregnancy during treatment.


Should you consult a doctor?

If you experience any unexpected or severe side effects after receiving Pemnat 100mg Injection, it is essential to seek medical attention promptly. Additionally, if you have a history of undergoing radiation therapy or have plans for it in the future, or if you have recently been vaccinated, it is crucial to inform your doctor before receiving this injection. These situations may require special considerations or adjustments to ensure the safe use of Pemnat 100mg Injection. Monitoring and guidance from a healthcare professional in these cases can help manage any potential risks and optimize the benefits of the treatment.


Side effects of Pemnat 100mg Injection

When taking Pemnat 100mg Injection, you may experience some side effects as your body adjusts to the medicine. These side effects usually do not require medical attention and may go away on their own. However, if these side effects persist or if you are concerned about them, it is important to consult your doctor. Common side effects of Pemnat 100mg Injection include nausea, vomiting, sore throat, loss of appetite, stomatitis (inflammation of the mouth), hair loss, low blood platelets, rash, fatigue, anemia, diarrhea, decreased white blood cell count, and neuropathy.

In addition to these common side effects, some individuals may also experience rectal inflammation or bleeding, inflammation and redness of the esophagus, infections, fever, sore throat, stomach pain, indigestion, constipation, mouth ulcers, tiredness, dehydration, dizziness, skin rash, flaky skin, changes in taste, muscle weakness, eye inflammation, irregular heartbeat, increase in liver and kidney enzymes, swelling of body parts, and inflammation of the gut. It is crucial to keep an eye out for these symptoms and consult your doctor if any of them occur.

While rare, there are more serious side effects that require immediate medical attention. If you experience fever, increased infections, chest pain, fast heart rate, signs of allergic reactions (such as skin rash, swelling of the face, lips, mouth, or throat), severe skin reactions with blistering and peeling of the skin, signs of low red blood cell count, increased tendency to bleed, unexpected bruising, or signs of a blood clot in the lungs, contact your doctor immediately. These severe side effects should not be ignored and necessitate prompt medical intervention to ensure your safety and well-being.


Safety advice

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liver

Pemnat 100mg Injection appears to be generally safe for individuals with liver disease. The available information indicates that adjusting the dosage of Pemnat 100mg Injection may not be necessary for such patients. It is recommended to consult with your healthcare provider before using this injection to ensure it is suitable for your specific condition.

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kidney

Pemnat 100mg Injection requires caution in patients with kidney disease. Dose adjustment may be necessary. Avoid in those with moderate to severe kidney disease. Consult your doctor before use.

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alcohol

When taking Pemnat 100mg Injection, it is safe to consume alcohol as no harmful side effects are known.

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driving

Pemnat 100mg Injection may make you feel tired, affecting your ability to drive.

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pregnancy

Pemnat 100mg Injection is not safe during pregnancy. Research shows it can harm the baby. Only use it if the doctor says it's necessary for a serious reason. Always talk to your doctor first.

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breastfeeding

During breastfeeding, caution is advised when using Pemnat 100mg Injection. It is recommended to postpone breastfeeding until the mother's treatment is finished and the drug has cleared from her system.


Age above 75(Geriatrics)

Pemnat 100mg Injection should be used with caution in elderly patients (aged 65 years and above). Consult your doctor before receiving it.

Age below 6 months(Pediatrics)

Pemnat 100mg Injection is generally not recommended for use in children and adolescents (under 18 years of age) due to lack of safety data. Therefore, consult your doctor before receiving it. 

Consumption warning before consuming Pemnat 100mg Injection

Before consuming Pemnat 100mg Injection, it is crucial to be aware of certain warnings for your safety. This medication is specifically prescribed for the treatment of non-small cell lung cancer and malignant pleural mesothelioma. It is administered as an injection by a qualified medical professional, and the dosage and frequency will be determined by your doctor based on your condition, which may change over time. It is essential to strictly adhere to the prescribed dosage as incorrect use can lead to severe side effects.

Common side effects of Pemnat 100mg Injection include nausea, vomiting, loss of appetite, and hair loss. This medication may also lower the number of blood cells, increasing the risk of infections. Regular blood tests are necessary to monitor blood cell counts and assess heart, liver, and blood uric acid levels. Prior to starting this treatment, inform your doctor about any pre-existing heart, liver, or kidney conditions, as well as any other medications you may be taking to avoid potential interactions.

It is crucial to note that Pemnat 100mg Injection is not recommended during pregnancy or breastfeeding, and effective contraception for both males and females is vital during treatment to prevent pregnancy. Taking these precautions can ensure the safe and effective use of this medication.


What happens if you take overdose of Pemnat 100mg Injection?

"Pemnat 100mg Injection is strictly administered by healthcare professionals in a hospital setting, reducing the risk of an overdose. It is important to seek medical advice from your doctor or nurse if you notice any unusual symptoms while receiving this medication."


Additional Information

Habit FormingNo
Chemical ClassGlutamic Acid Derivatives
Therapeutic ClassANTI NEOPLASTICS
Action ClassAntimetabolites

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Disclaimer

The information provided on this website is to the best of our abilities to ensure it is accurate, reliable, and reviewed by a team of professionals. It should not be used to diagnose, prevent, or cure any health problem. The information presented here is not intended to create a doctor-patient relationship or replace a registered medical practitioner's advice, diagnosis, or treatment. The absence or provision of any information or warning regarding any medicine should not be assumed as an implied or explicit assurance of safety or efficacy. We highly recommend consulting your registered medical practitioner for all queries or doubts related to your medical condition. Do not ignore professional medical advice or delay seeking it based on the content encountered on our website. We intend to support, not replace, the doctor-patient relationship.

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Dr. Archana Prabhakar

MBBS, M.Med (Family Medicine)

Last update on 11-Feb-2025