Pemgem 100mg Injection
By Pemgem
Rx
1 Injection in a Vial

Composition
Pemetrexed(100mg)

Manufacturer - Dr Reddy's Laboratories Ltd
Dr. Reddy's Laboratories Ltd., 8-2-337, Road No. 3, Banjara Hills, Hyderabad, Telangana 500034, INDIA

Expires on or after
April, 2026
About Pemgem 100mg Injection
Pemgem 100mg Injection is a medication used to treat non-small cell lung cancer and malignant pleural mesothelioma. Administered through injection by a qualified medical professional, the dosage and frequency will be determined by your doctor based on your specific condition. It is crucial to follow your doctor's instructions precisely to avoid any serious side effects. The effects of the medication may take some time to manifest, so it is important not to discontinue its use without consulting your doctor.
Common side effects of Pemgem 100mg Injection include nausea, vomiting, loss of appetite, and hair loss. It may also reduce certain blood cell counts, making you more susceptible to infections. Regular blood tests will be necessary to monitor your blood cells, as well as heart, liver, and blood uric acid levels during treatment.
Before starting Pemgem 100mg Injection, inform your doctor about any existing heart, liver, or kidney issues, as well as any medications you are currently taking for infections. Due to potential interactions, it is crucial to disclose all medications in use. This medication is not recommended during pregnancy or breastfeeding. Effective contraception is required for both men and women during treatment to prevent pregnancy.
Pemgem 100mg Injection contains Pemetrexed, classified as an Anticancer agent, specifically used for advanced non-small cell lung cancer and malignant pleural mesothelioma. It is often used in conjunction with other anti-cancer drugs for more effective results. Prior to treatment, inform your doctor of any lung, liver, kidney, or heart problems, as well as any recent radiation therapy or upcoming vaccinations.
The most commonly reported side effects of Pemgem 100mg Injection include increased susceptibility to infections, sore throat, nausea, vomiting, stomach pain, dizziness, tiredness, weight loss, taste changes, skin rash, hair loss, and mouth ulcers. It is advised to promptly contact your doctor if any of these side effects worsen during treatment.
Benefits
Pemgem 100mg Injection offers significant benefits in the treatment of two types of cancer: non-small cell lung cancer and malignant pleural mesothelioma. For non-small cell lung cancer, which is a major type of lung cancer that affects both smokers and non-smokers, this medication can be used either on its own or in combination with other treatments. It is a strong and potentially harmful medicine, so it is crucial to have a detailed discussion with your doctor about the risks and advantages of the treatment. While undergoing this treatment, it is advised to avoid alcohol consumption and ensure proper hydration by drinking sufficient water.
In the case of malignant pleural mesothelioma, a highly aggressive form of lung cancer that develops in the lungs and the inner side of the ribs, Pemgem 100mg Injection is employed in combination with other medications to combat the disease. The injection works by targeting and destroying cancer cells, preventing their further growth and spread to other parts of the body. To maximize the benefits of this treatment, it is essential to strictly adhere to your doctor's guidance and promptly address any concerns or queries you may have.
Overall, Pemgem 100mg Injection demonstrates promising outcomes in the management of non-small cell lung cancer and malignant pleural mesothelioma by effectively combating cancer cells and impeding their progression. Consulting with your doctor and following their recommendations diligently can help optimize the therapeutic benefits of this medication in your cancer treatment regimen.
How to use the Pemgem 100mg Injection
To use Pemgem 100mg Injection, you should always remember that it must be administered by a doctor or a nurse. This particular medication is given directly into a vein as an intravenous infusion. It's crucial not to attempt to administer it to yourself. Your doctor will carefully determine the right dosage and duration of treatment tailored specifically for you. This assessment will take into account factors such as your age, body weight, and the specific disease or condition being treated. By following these instructions and allowing a healthcare professional to administer Pemgem 100mg Injection, you are ensuring the safest and most effective use of this medication for your health needs.
Uses of Pemgem 100mg Injection
Pemgem 100mg Injection is used to treat advanced non-small cell lung cancer (NSCLC) and malignant pleural mesothelioma, which is a type of cancer affecting the protective layer of the lungs. It is specifically designed to help patients suffering from these conditions by targeting the cancer cells and helping to slow down the progression of the diseases. By administering Pemgem 100mg Injection as prescribed by a healthcare professional, patients can benefit from its therapeutic effects in managing the symptoms and improving their overall quality of life.
What conditions Pemgem 100mg Injection treats?
Pemgem 100mg Injection is prescribed for treating non-small cell lung cancer and malignant pleural mesothelioma. Non-small cell lung cancer affects smokers and non-smokers and requires discussion of risks and benefits with your doctor. Avoid alcohol and stay hydrated during treatment. Malignant pleural mesothelioma, a aggressive lung cancer, is treated with Pemgem 100mg Injection to kill cancer cells and prevent further spread. Follow doctor's instructions closely and seek clarifications when needed. Regular blood tests are necessary due to potential side effects like decreased blood cells. Effective contraception must be used to prevent pregnancy during treatment.
Should you consult a doctor?
If you experience any unexpected or severe side effects after receiving Pemgem 100mg Injection, it is essential to seek medical attention promptly. Additionally, if you have a history of undergoing radiation therapy or have plans for it in the future, or if you have recently been vaccinated, it is crucial to inform your doctor before receiving this injection. These situations may require special considerations or adjustments to ensure the safe use of Pemgem 100mg Injection. Monitoring and guidance from a healthcare professional in these cases can help manage any potential risks and optimize the benefits of the treatment.
Side effects of Pemgem 100mg Injection
When taking Pemgem 100mg Injection, you may experience some side effects as your body adjusts to the medicine. These side effects usually do not require medical attention and may go away on their own. However, if these side effects persist or if you are concerned about them, it is important to consult your doctor. Common side effects of Pemgem 100mg Injection include nausea, vomiting, sore throat, loss of appetite, stomatitis (inflammation of the mouth), hair loss, low blood platelets, rash, fatigue, anemia, diarrhea, decreased white blood cell count, and neuropathy.
In addition to these common side effects, some individuals may also experience rectal inflammation or bleeding, inflammation and redness of the esophagus, infections, fever, sore throat, stomach pain, indigestion, constipation, mouth ulcers, tiredness, dehydration, dizziness, skin rash, flaky skin, changes in taste, muscle weakness, eye inflammation, irregular heartbeat, increase in liver and kidney enzymes, swelling of body parts, and inflammation of the gut. It is crucial to keep an eye out for these symptoms and consult your doctor if any of them occur.
While rare, there are more serious side effects that require immediate medical attention. If you experience fever, increased infections, chest pain, fast heart rate, signs of allergic reactions (such as skin rash, swelling of the face, lips, mouth, or throat), severe skin reactions with blistering and peeling of the skin, signs of low red blood cell count, increased tendency to bleed, unexpected bruising, or signs of a blood clot in the lungs, contact your doctor immediately. These severe side effects should not be ignored and necessitate prompt medical intervention to ensure your safety and well-being.
Safety advice

liver
Pemgem 100mg Injection appears to be generally safe for individuals with liver disease. The available information indicates that adjusting the dosage of Pemgem 100mg Injection may not be necessary for such patients. It is recommended to consult with your healthcare provider before using this injection to ensure it is suitable for your specific condition.

kidney
Pemgem 100mg Injection requires caution in patients with kidney disease. Dose adjustment may be necessary. Avoid in those with moderate to severe kidney disease. Consult your doctor before use.

alcohol
When taking Pemgem 100mg Injection, it is safe to consume alcohol as no harmful side effects are known.

driving
Pemgem 100mg Injection may make you feel tired, affecting your ability to drive.

pregnancy
Pemgem 100mg Injection is not safe during pregnancy. Research shows it can harm the baby. Only use it if the doctor says it's necessary for a serious reason. Always talk to your doctor first.

breastfeeding
During breastfeeding, caution is advised when using Pemgem 100mg Injection. It is recommended to postpone breastfeeding until the mother's treatment is finished and the drug has cleared from her system.
Age above 75(Geriatrics)
Age below 6 months(Pediatrics)
Consumption warning before consuming Pemgem 100mg Injection
Before consuming Pemgem 100mg Injection, it is crucial to be aware of certain warnings for your safety. This medication is specifically prescribed for the treatment of non-small cell lung cancer and malignant pleural mesothelioma. It is administered as an injection by a qualified medical professional, and the dosage and frequency will be determined by your doctor based on your condition, which may change over time. It is essential to strictly adhere to the prescribed dosage as incorrect use can lead to severe side effects.
Common side effects of Pemgem 100mg Injection include nausea, vomiting, loss of appetite, and hair loss. This medication may also lower the number of blood cells, increasing the risk of infections. Regular blood tests are necessary to monitor blood cell counts and assess heart, liver, and blood uric acid levels. Prior to starting this treatment, inform your doctor about any pre-existing heart, liver, or kidney conditions, as well as any other medications you may be taking to avoid potential interactions.
It is crucial to note that Pemgem 100mg Injection is not recommended during pregnancy or breastfeeding, and effective contraception for both males and females is vital during treatment to prevent pregnancy. Taking these precautions can ensure the safe and effective use of this medication.
What happens if you take overdose of Pemgem 100mg Injection?
"Pemgem 100mg Injection is strictly administered by healthcare professionals in a hospital setting, reducing the risk of an overdose. It is important to seek medical advice from your doctor or nurse if you notice any unusual symptoms while receiving this medication."
Additional Information
Habit Forming | No |
Chemical Class | Glutamic Acid Derivatives |
Therapeutic Class | ANTI NEOPLASTICS |
Action Class | Antimetabolites |
FAQs
Disclaimer
The information provided on this website is to the best of our abilities to ensure it is accurate, reliable, and reviewed by a team of professionals. It should not be used to diagnose, prevent, or cure any health problem. The information presented here is not intended to create a doctor-patient relationship or replace a registered medical practitioner's advice, diagnosis, or treatment. The absence or provision of any information or warning regarding any medicine should not be assumed as an implied or explicit assurance of safety or efficacy. We highly recommend consulting your registered medical practitioner for all queries or doubts related to your medical condition. Do not ignore professional medical advice or delay seeking it based on the content encountered on our website. We intend to support, not replace, the doctor-patient relationship.
₹1378.5
Inclusive of all taxes
Content verified by

Dr. Archana Prabhakar
MBBS, M.Med (Family Medicine)
Last update on 11-Feb-2025