Pemeplast 500 Injection
By Pemeplast
Rx
1 Powder for Injection in a Vial

Composition
Pemetrexed(500mg)

Manufacturer - Neon Laboratories Ltd
140, Damji Samji Industrial Complex, Mahakali Caves Rd., Andheri(East), Mumbai-93.

Expires on or after
July, 2025
About Pemeplast 500 Injection
Pemeplast 500 Injection is a medication used in the treatment of non-small cell lung cancer and malignant pleural mesothelioma. It is administered as an injection by a qualified medical professional. Your doctor will determine the appropriate dosage and frequency of administration based on your specific condition, which may be subject to change over time. It is crucial to follow your doctor's instructions precisely to avoid serious side effects that may occur if taken incorrectly or in excessive amounts.
It is important to note that the benefits of Pemeplast 500 Injection may not be immediately noticeable, and it could take several weeks or even months before you begin to feel its effects. Therefore, it is essential to continue taking the medication as prescribed by your doctor unless instructed otherwise.
Common side effects associated with Pemeplast 500 Injection include nausea, vomiting, loss of appetite, and hair loss. Additionally, this medication may lead to a decrease in the number of blood cells, making you more susceptible to infections. Regular blood tests are necessary to monitor your blood cell count, as well as your heart, liver, and blood uric acid levels.
Before starting treatment with Pemeplast 500 Injection, inform your doctor if you have heart disease, liver or kidney issues, or if you are taking any medications for infections. It is crucial to disclose all medications you are currently using, as interactions with other drugs can occur. This medication is not recommended during pregnancy or breastfeeding, and both males and females should use effective contraception to prevent pregnancy while undergoing treatment.
In conclusion, the detailed information provided above highlights the essential aspects of Pemeplast 500 Injection, its usage, potential side effects, and precautions to be taken before and during treatment.
Benefits
Pemeplast 500 Injection offers multiple benefits for patients dealing with two types of cancer - non-small cell lung cancer and malignant pleural mesothelioma. In cases of non-small cell lung cancer, which is prevalent among both smokers and non-smokers, this medication serves as a powerful tool in combating the disease. It can be administered alone or in conjunction with other medications to enhance its effectiveness. It is important to note that Pemeplast 500 Injection is a potent and highly toxic drug, underscoring the necessity of discussing potential risks and advantages with one's healthcare provider before starting treatment. Patients are advised to abstain from alcohol consumption during the course of this treatment and are encouraged to stay well-hydrated by consuming plenty of water.
In the context of malignant pleural mesothelioma, a particularly aggressive form of lung cancer, Pemeplast 500 Injection plays a crucial role in the therapeutic regimen. When used in combination with other medications, this injection works by eradicating cancer cells and halting their proliferation. By impeding the spread of cancer cells to other parts of the body, this drug helps contain the disease and improve the patient's prognosis. To derive maximum benefit from this treatment, it is imperative for individuals to adhere closely to their doctor's guidance and promptly seek clarification on any uncertainties that may arise. With its ability to target and combat these challenging forms of cancer, Pemeplast 500 Injection stands as a valuable option in the medical arsenal against non-small cell lung cancer and malignant pleural mesothelioma.
How to use the Pemeplast 500 Injection
When it comes to using Pemeplast 500 Injection, it is important to let your doctor or nurse administer it to you. This medicine should not be self-administered. It will be given to you by a medical professional directly into a vein through an intravenous infusion. Your doctor will determine the right dosage and how long you should receive this treatment based on factors like your age, weight, and the specific condition being treated. Trust your healthcare provider to handle the administration of Pemeplast 500 Injection safely and effectively for your well-being.
Uses of Pemeplast 500 Injection
Pemeplast 500 Injection is used to treat advanced non-small cell lung cancer (NSCLC) and malignant pleural mesothelioma, which is a type of cancer affecting the protective layer of the lungs. This medication is beneficial for patients diagnosed with these specific types of cancer to help alleviate symptoms and potentially slow down the progression of the disease. By targeting the tumor cells in non-small cell lung cancer and malignant pleural mesothelioma, Pemeplast 500 Injection plays a crucial role in the treatment process for those affected by these conditions.
What conditions Pemeplast 500 Injection treats?
Pemeplast 500 Injection is utilized in treating non-small cell lung cancer and malignant pleural mesothelioma. Non-small cell lung cancer affects both smokers and non-smokers, and this injection can be given alone or with other medications. It is crucial to weigh the risks and benefits with your doctor before starting treatment. Malignant pleural mesothelioma, a very aggressive type of lung cancer, is treated with Pemeplast 500 Injection along with other medicines. This injection works by killing cancer cells and preventing their further growth, reducing the chances of cancer spreading. Following your doctor's guidance is essential for effective treatment.
Should you consult a doctor?
Before receiving Pemeplast 500 Injection, it is important to consult your doctor if you have a history of undergoing or are planning to have radiation therapy. Additionally, if you have recently received any vaccinations, it is essential to inform your doctor. These factors can impact the effectiveness and safety of the medication, and your doctor needs to be aware of your medical history to determine the best course of treatment. If you experience any unusual symptoms or side effects after receiving the injection, such as severe nausea, vomiting, or difficulty breathing, seek medical attention immediately. Your doctor will be able to provide the necessary guidance and support to ensure your well-being.
Side effects of Pemeplast 500 Injection
Common side effects of Pemeplast 500 Injection include nausea, vomiting, sore throat, loss of appetite, stomatitis (mouth inflammation), hair loss, low blood platelets, rash, fatigue, anemia, diarrhea, decreased white blood cell count, and neuropathy. Additionally, patients may experience rectal inflammation or bleeding, esophagus inflammation and redness, infections, fever, sore throat, stomach pain, indigestion, constipation, mouth ulcers, tiredness, dehydration, dizziness, skin rash, flaky skin, changes in sensation, eye inflammation, irregular heartbeat, liver and kidney enzyme increases, body parts swelling, and gut inflammation.
It is important to note that most side effects are temporary and may resolve as the body adjusts to the medication. However, if these side effects persist or cause concern, it is advisable to consult with a healthcare provider. In some cases, immediate medical attention is necessary if severe side effects occur after receiving Pemeplast 500 Injection. These serious side effects may include fever, increased infections, chest pain, fast heart rate, mouth inflammation with pain and swelling, allergic reactions with skin rash and swelling of the face or throat, severe skin reactions with blistering and peeling, signs of low red blood cells, increased bleeding tendency, unexpected bruising, and signs of blood clot in the lungs.
If any of these serious side effects are experienced, it is crucial to contact a doctor promptly for appropriate evaluation and management.
Safety advice

liver
When considering the use of Pemeplast 500 Injection in patients with liver disease, it is likely safe based on available information. The data indicates that adjusting the dose of Pemeplast 500 Injection may not be necessary for patients dealing with liver issues. However, it is essential to consult with your doctor before proceeding with this medication to ensure safety and efficacy.

kidney
Pemeplast 500 Injection requires caution in patients with kidney disease. Dose adjustment might be necessary. Avoid in cases of moderate to severe kidney issues. Consult your doctor for guidance.

alcohol
When taking Pemeplast 500 Injection, it is safe to consume alcohol as it does not lead to any negative side effects.

driving
When using Pemeplast 500 Injection, be cautious when driving as it may cause tiredness which can impact your ability to drive safely.

pregnancy
Pemeplast 500 Injection is considered unsafe during pregnancy, with a confirmed risk to the developing baby. In rare life-threatening cases, a doctor may choose to prescribe it if benefits outweigh risks. Always consult your doctor regarding its use.

breastfeeding
During breastfeeding, Pemeplast 500 Injection should be used with caution. It's recommended to pause breastfeeding until the mother's treatment is finished and the drug is fully eliminated from her body.
Age above 75(Geriatrics)
Age below 6 months(Pediatrics)
Consumption warning before consuming Pemeplast 500 Injection
Before consuming Pemeplast 500 Injection, it is important to note that this medication is primarily used in the treatment of non-small cell lung cancer and malignant pleural mesothelioma. It is administered via injection by a qualified medical professional. Your doctor will determine the appropriate dosage and frequency based on your specific condition, and it is crucial to follow their instructions precisely to avoid serious side effects.
Common side effects may include nausea, vomiting, loss of appetite, and hair loss. Additionally, this medication can lower your blood cell count, making you more vulnerable to infections. Regular blood tests are necessary to monitor your blood cells, heart, liver, and blood uric acid levels.
Prior to starting treatment, inform your doctor of any existing heart, liver, or kidney ailments, as well as any other medications you are taking. It is important to avoid pregnancy while using this medication, and both males and females should use effective contraception throughout the treatment period. Be aware that certain medications may interact with or be affected by Pemeplast 500 Injection, so full disclosure to your doctor about your medication regimen is crucial.
What happens if you take overdose of Pemeplast 500 Injection?
Pemeplast 500 Injection is typically given by a doctor or nurse in a hospital setting, reducing the risk of an overdose. It is crucial to follow medical guidance and not self-administer this medication. In the rare event of a potential overdose, symptoms may include severe nausea, vomiting, or dizziness. If you notice any unusual symptoms after receiving the injection, promptly seek advice from your healthcare provider. Your doctor or nurse can assess your condition and recommend appropriate steps to ensure your well-being. Your safety and health are of utmost importance when receiving treatment with Pemeplast 500 Injection.
Additional Information
Habit Forming | No |
Chemical Class | Glutamic Acid Derivatives |
Therapeutic Class | ANTI NEOPLASTICS |
Action Class | Antimetabolites |
FAQs
Disclaimer
The information provided on this website is to the best of our abilities to ensure it is accurate, reliable, and reviewed by a team of professionals. It should not be used to diagnose, prevent, or cure any health problem. The information presented here is not intended to create a doctor-patient relationship or replace a registered medical practitioner's advice, diagnosis, or treatment. The absence or provision of any information or warning regarding any medicine should not be assumed as an implied or explicit assurance of safety or efficacy. We highly recommend consulting your registered medical practitioner for all queries or doubts related to your medical condition. Do not ignore professional medical advice or delay seeking it based on the content encountered on our website. We intend to support, not replace, the doctor-patient relationship.
₹2506
Inclusive of all taxes
Content verified by

Dr. Abdullah Khan
MBBS - General Medicine
Last update on 01-Oct-2024