Pegfeel Injection

By Pegfeel

Rx

0ml Injection in a Prefilled syringe

Composition icon

Composition

Granulocyte Colony Stimulating Factor(6mg)

Manufacturer - Dr Reddy's Laboratories Ltd icon

Manufacturer - Dr Reddy's Laboratories Ltd

Dr. Reddy's Laboratories Ltd., 8-2-337, Road No. 3, Banjara Hills, Hyderabad, Telangana 500034, INDIA

Expires on or after icon

Expires on or after

July, 2025

About Pegfeel Injection

Pegfeel Injection is a medication used to prevent infections that may occur after undergoing chemotherapy treatment. It is classified as a growth factor that stimulates the bone marrow to produce white blood cells, which play a crucial role in protecting the body against infections. The injection is administered by a qualified medical professional, and it is important to follow your doctor's advice regarding the duration of treatment. Regular monitoring through blood tests is recommended to assess the levels of blood cells and bone density while using this medication.

Common side effects of Pegfeel Injection include bone pain, weakness, joint pain, headache, and rash. It is normal to experience pain or redness at the injection site, but it is essential to inform your doctor if you notice any persistent lump, swelling, or bruising. While Pegfeel Injection helps reduce the risk of infections, it may not provide complete protection. If you experience symptoms like fever, chills, rash, sore throat, or swelling around the face or neck, it is important to consult your healthcare provider promptly.

It is crucial to disclose all medications you are taking to your healthcare team, as interactions with other drugs may occur. Pregnant women and those who are breastfeeding are advised not to use Pegfeel Injection. Effective contraception is necessary for both males and females during the treatment period to avoid the risk of pregnancy.

PEGFEEL PREFILLED SYRINGE(PFS) specifically contains Pegfilgrastim, which falls under the group of Colony Stimulating Factors. This medication helps prevent the depletion of white blood cells in the blood resulting from chemotherapy, reducing the risk of neutropenia and febrile neutropenia among patients undergoing chemotherapy. Before receiving PEGFEEL PREFILLED SYRINGE(PFS), it is important to discuss any lung or blood circulation issues with your doctor. Moreover, inform your doctor if you have allergies to Pegfilgrastim or filgrastim, or have conditions such as breast cancer, lung cancer, or anemia.

Some of the common side effects associated with PEGFEEL PREFILLED SYRINGE(PFS) include bone pain, nausea, headache, skin rashes, injection site discomfort, and muscle pain. If you experience any of these side effects significantly, it is advised to inform your doctor promptly.


Benefits

Pegfeel Injection, containing Pegfilgrastim as the active ingredient, offers several benefits in the prevention of infections after chemotherapy. This medication functions by increasing the production of white blood cells, which are crucial for our immune system to fight off infections. By stimulating the immune system, Peg Frastim helps the body generate more white blood cells, enhancing its ability to combat infections effectively.

One of the primary advantages of Pegfeel Injection is its effectiveness in boosting the white blood cell count following cancer treatment, chemotherapy, bone marrow transplantation, severe persistent neutropenia, neutropenia in HIV patients, and before stem cell donation. This medication acts as a growth factor that closely resembles a natural protein produced by the body, known as granulocyte-colony stimulating factor. By encouraging the bone marrow to produce more white blood cells, Peg Frastim plays a vital role in enhancing the body's defense mechanisms against various infections.

It is essential to use Pegfeel Injection under medical supervision to ensure safe and effective treatment. Patients should avoid crowded places and maintain good hygiene practices, such as washing hands frequently, to reduce the risk of infections. Additionally, staying well-hydrated with plenty of fluids, unless advised otherwise by a healthcare professional, can further support the body during the treatment process.

Overall, Pegfeel Injection is a valuable medication that helps in preventing infections after chemotherapy by stimulating the immune system and boosting white blood cell production. It is important for individuals undergoing cancer treatment or other relevant medical conditions to consider the benefits of this medication in improving their immune responses and overall well-being.


How to use the Pegfeel Injection

To use Pegfeel Injection properly, it is important to follow the instructions provided by your doctor or nurse, who will be responsible for administering the medicine. It is crucial not to attempt self-administration of the injection. The Pegfeel Injection comes in a 0.6 ml dosage, and a trained healthcare professional will carry out the administration. By ensuring that only a healthcare professional gives you the injection, you promote safe usage and reduce the risk of complications. Remember, always rely on trained medical personnel for the administration of Pegfeel Injection to ensure the best possible outcome for your treatment.


Uses of Pegfeel Injection

Pegfeel Injection is primarily used for the prevention of infections following chemotherapy treatment. It is specifically effective in managing neutropenia, a condition characterized by abnormally low levels of neutrophils, a type of white blood cell that plays a crucial role in fighting infections. By boosting the production of neutrophils, Peg Frastim helps the body strengthen its immune defense system, thus reducing the risk of infections in individuals undergoing chemotherapy. This medication acts as a valuable tool in protecting patients with compromised immune systems who are susceptible to infections during cancer treatment.


What conditions Pegfeel Injection treats?

Neutropenia is a condition where the body has lower than normal levels of neutrophils, which are a type of white blood cells that help fight infections. This can make it harder for the body to defend against bacteria, putting individuals at a higher risk for various illnesses. Causes of neutropenia include cancers such as leukemia, cancer treatments like radiotherapy, and infections like HIV or hepatitis.


Should you consult a doctor?

Seek medical attention if you experience persistent bone pain, weakness, joint pain, rash, headache, or injection site issues while using Pegfeel Injection. Inform your doctor immediately if you notice unusual symptoms like a lump, swelling, or persistent bruising at the injection site. Additionally, contact your healthcare provider if you develop symptoms of infection such as fever, chills, sore throat, rash, or facial or neck swelling. It is crucial to consult a doctor if you have concerns about side effects or if they persist. Remember to inform your healthcare team about all the medications you are taking as some may interact with Peg Frastim. If you are pregnant, breastfeeding, or planning to conceive, discuss the use of effective contraception during treatment with your doctor.


Side effects of Pegfeel Injection

When using Pegfeel Injection, you may experience various side effects. These side effects are usually mild and go away as your body gets used to the medicine. Some common side effects include bone pain, weakness, joint pain, rash, headache, nausea, back pain, pain in extremities, and increased white blood cell count. You might also notice muscle pain, elevated lactate dehydrogenase levels in the blood, low blood platelets, and pain at the injection site. Other potential side effects include increased uric acid levels in the blood, oropharyngeal pain, hair loss, fatigue, increased liver enzymes, diarrhea, decreased appetite, constipation, and injection site reactions like pain, swelling, and redness. If any of these side effects persist or concern you, it's essential to consult your healthcare provider for guidance and support.


Safety advice

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liver

Limited information is currently available regarding the safe use of Pegfeel Injection in individuals with liver disease. It is strongly advised to seek guidance from your healthcare provider before starting this medication to ensure its appropriateness given your liver health.

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kidney

Limited information is available on using Pegfeel Injection in patients with kidney disease. Please consult your doctor.

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alcohol

It is uncertain if alcohol is safe with Pegfeel Injection, so consult your doctor.

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driving

It is not clear if Pegfeel Injection affects driving ability. Avoid driving if you have symptoms like reduced focus or slower reactions.

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pregnancy

Pegfeel Injection may be unsafe during pregnancy, with animal studies showing potential harm to the baby. Your doctor will assess risks versus benefits before prescribing. Seek advice from your doctor.

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breastfeeding

Pegfeel Injection is considered safe while breastfeeding based on limited human data. The drug is unlikely to pose a significant risk to the baby.


Consumption warning before consuming Pegfeel Injection

Before using Pegfeel Injection, consult your doctor if you have experienced a skin reaction to any medication. It is essential to inform your healthcare provider if you are pregnant, breastfeeding, or have conditions such as renal dysfunction, blood cancer, or leucocytosis. Regular monitoring of white blood cell counts through blood tests is necessary while using this injection. Store Pegfeel Injection in a refrigerator between 2-8 degrees Celsius, as it is a cold chain medicine. Failure to store it properly may result in a loss of effectiveness. Keep your doctor updated about your medical condition and all medications to prevent any adverse reactions.


Disease interactions

When using Peg-Religrast 6 mg Injection 0.6 ml, it's important to be aware of potential interactions with certain disease conditions. Specifically, this medication may have implications for individuals with glomerulonephritis, which is the acute inflammation of the kidneys. Patients with leucocytosis, characterized by a high white blood cell count, should also exercise caution when using this injection. Furthermore, individuals with myeloid tumors, a type of cancer affecting bone marrow cells, should consult their healthcare provider before starting treatment with Peg-Religrast. Understanding these disease drug interactions is crucial for managing health effectively.


What if you forgot to take Pegfeel Injection?

If you forget to take your scheduled dose of Pegfeel Injection, it's important to seek advice from your doctor. It is recommended to consult with your healthcare provider to determine the best course of action when a dose is missed. Following your doctor's guidance is crucial to effectively manage your treatment plan with Pegfeel Injection.


Related lab tests

In order to monitor the effects of Pegfeel Injection on the body, several related lab tests can be conducted. One important lab test is the Complete Blood Count (CBC). This test provides valuable information about the different types of blood cells in the body, such as red blood cells, white blood cells, and platelets. By analyzing the CBC, healthcare providers can assess the impact of the medication on the production and function of these blood cells.

Another relevant lab test is the Peripheral Smear Examination. This test involves examining a sample of blood under a microscope to evaluate the size, shape, and structure of the blood cells. It helps in detecting any abnormalities in the blood cells, such as immature or abnormal cells. By conducting a peripheral smear examination, healthcare providers can further assess the impact of Pegfeel Injection on the blood cells and identify any potential side effects.

List of Related Lab Tests:
1. Complete Blood Count (CBC)
2. Peripheral Smear Examination


Additional Information

Habit FormingNo
Chemical ClassCytokine Glycoprotein
Therapeutic Class-
Action ClassGranulocyte-colony stimulating factor (G-CSF)

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Disclaimer

The information provided on this website is to the best of our abilities to ensure it is accurate, reliable, and reviewed by a team of professionals. It should not be used to diagnose, prevent, or cure any health problem. The information presented here is not intended to create a doctor-patient relationship or replace a registered medical practitioner's advice, diagnosis, or treatment. The absence or provision of any information or warning regarding any medicine should not be assumed as an implied or explicit assurance of safety or efficacy. We highly recommend consulting your registered medical practitioner for all queries or doubts related to your medical condition. Do not ignore professional medical advice or delay seeking it based on the content encountered on our website. We intend to support, not replace, the doctor-patient relationship.

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Dr. Abdullah Khan

MBBS - General Medicine

Last update on 11-Feb-2025