Pangraf 0.25 Capsule
By Pangraf
Rx
10 Capsule in a Strip

Composition
Tacrolimus(0.25mg)

Manufacturer - Panacea Biotec Ltd
Ambala- Chandigarh Highway, Lalru – 140501, Punjab

Expires on or after
February, 2026
About Pangraf 0.25 Capsule
Pangraf 0.25 Capsule, containing Tacrolimus, is classified as an immunosuppressant medication used to safeguard against organ rejection in patients who have undergone organ transplants, such as liver, kidney, or heart transplants. When a person receives a new organ, their immune system might view it as a threat and attempt to reject it. Pangraf 0.25 Capsule works by reducing the activity of T and B lymphocytes, which are immune system cells responsible for attacking foreign substances. By doing so, Pangraf 0.25 Capsule prevents organ rejection and assists the body in accepting the transplanted organ.
It is crucial to take Pangraf 0.25 Capsule precisely as prescribed by your physician. The dosage and frequency will vary based on the type of transplant, individual body weight, and other medications being taken concurrently. It is recommended to consume Pangraf 0.25 Capsule on an empty stomach, at least one hour before or two hours after eating. Consistency in taking this medication is essential to achieve maximum benefits. Even if you feel well, it is important to continue taking Pangraf 0.25 Capsule to decrease the risk of organ rejection.
While Pangraf 0.25 Capsule is effective in preventing rejection, it may cause side effects that require attention, such as diabetes, kidney issues, tremors, infections, high blood pressure, and insomnia. If you experience persistent or worsening side effects, it is advisable to notify your doctor promptly. Additionally, Pangraf 0.25 Capsule weakens the immune system, increasing susceptibility to infections. Thus, it is crucial to practice caution and limit sun exposure to reduce the risk of skin cancer.
Prior to starting Pangraf 0.25 Capsule, inform your doctor about any existing health conditions, such as kidney, liver, or heart problems, diabetes, or high blood pressure. Disclose all other medications being taken, particularly those for infections, pain relief, or arthritis, as they may interact with Pangraf 0.25 Capsule. Both men and women using Pangraf 0.25 Capsule are advised to utilize effective birth control methods to prevent pregnancy. If pregnancy is a possibility or if you are breastfeeding, consult your doctor for guidance before using Pangraf 0.25 Capsule. Regular medical tests and blood pressure monitoring will be necessary during treatment to evaluate progress and ensure your well-being.
Benefits
Pangraf 0.25 Capsule, a medication that falls under the category of immunosuppressants, plays a crucial role in preventing organ rejection in transplant patients. Organ rejection occurs when the immune system identifies the new organ as a threat and launches an attack against it. By weakening the immune response, which typically fights infections, this medication significantly reduces the risk of the body rejecting the transplanted organ. Working in conjunction with other medicines, Pangraf 0.25 Capsule enhances the success rate of transplant operations. It contains Tacrolimus, an immunosuppressant that targets the T and B lymphocytes - key players in the immune system's defense mechanism against foreign substances. By suppressing the activity of these cells, which would normally target foreign invaders, Pangraf 0.25 Capsule facilitates the body's acceptance of the new organ and effectively prevents organ rejection in patients who have undergone organ transplants. It is important to adhere to the prescribed dosage and continue taking the medication until advised otherwise by a healthcare professional.
How to use the Pangraf 0.25 Capsule
To use Pangraf 0.25 Capsule, follow your doctor's instructions on the dose and duration. It's important to take this medicine on an empty stomach. If you are taking the capsule form, swallow it whole with water. Do not crush, break, or chew the capsule. If you are taking the granules, mix them with water to create an oral suspension. Drink the suspension immediately and do not store it for later use.
Take Pangraf 0.25 Capsule 1 hour before meals or 2-3 hours after meals, or as directed by your physician. Swallow the capsule with a glass of water and do not crush or chew it. Your doctor will determine the right dose and duration of therapy based on factors like your age, body weight, and medical condition. It's important not to stop taking Pangraf 0.25 Capsule without consulting your doctor first.
Uses of Pangraf 0.25 Capsule
The primary use of Pangraf 0.25 Capsule is for preventing organ rejection in transplant patients. It helps in preventing the rejection of transplanted organs, ensuring the body does not attack the newly transplanted organ. Pangraf 0.25 Capsule is also effective in preventing graft rejection that may occur after an organ transplantation procedure. By taking this medication as prescribed, transplant patients can help maintain the functionality and health of their transplanted organ.
What conditions Pangraf 0.25 Capsule treats?
Organ rejection is a condition where the body's immune system sees a transplanted organ as foreign and reacts to get rid of it. It can happen quickly (hyperacute), within a few months (acute), or after a year or more (chronic). Symptoms differ based on the organ transplanted but include pain, fever, and feeling unwell. If you notice these signs, seek medical help right away.
Should you consult a doctor?
It is important to seek advice from your doctor before taking Pangraf 0.25 Capsule if you have upcoming vaccination schedules. Notify your doctor if you have high blood cholesterol or potassium levels. If you experience any unexpected or severe side effects while taking this medication, consult your doctor immediately for guidance and proper evaluation. Your doctor will be able to provide you with the necessary support and advice to ensure your well-being while taking Pangraf 0.25 Capsule.
Side effects of Pangraf 0.25 Capsule
When taking Tacrograf 0.25 Capsules, some common side effects may occur as your body gets used to the medication. These include increased blood sugar levels, kidney damage, difficulty sleeping, tremors, high blood pressure, and the risk of infections. Other potential side effects to be aware of are nausea, diarrhea, headache, constipation, fever, and further kidney problems. Additionally, some individuals may experience liver problems, feeling shaky, stomach issues, mouth ulcers, changes in blood cholesterol levels, or emotional symptoms like anxiety or depression. Physical effects may include skin rash, muscle pain, weight gain, and changes in vision or hearing sensitivity. It is important to contact your healthcare provider if you notice severe stomach pain, signs of skin or lymph cancer, increased infections, flu-like symptoms, signs of brain infection, kidney damage symptoms, vision changes, allergic reactions, or signs of heart problems while taking this medication.
Safety advice

liver
For individuals with liver disease, caution is advised when using Pangraf 0.25 Capsule. It may be necessary to adjust the dose of the medication. It is important to consult your doctor before taking Pangraf 0.25 Capsule if you have any liver-related issues.

kidney
Pangraf 0.25 Capsule requires caution in patients with kidney disease. Adjusting the dose might be necessary. Always consult your doctor for guidance.

alcohol
It is unsafe to drink alcohol while taking Pangraf 0.25 Capsule. Drinking alcohol can have negative effects when combined with this medication.

driving
When taking Pangraf 0.25 Capsule, be cautious while driving. This medication may reduce alertness, impact vision, and cause drowsiness or dizziness. Avoid driving if you experience these effects.

pregnancy
Pangraf 0.25 Capsule may not be safe during pregnancy. Animal studies have shown potential harm to the developing baby. Your doctor will assess the risks and benefits before prescribing this medication. Consult your doctor for advice.

breastfeeding
Caution is advised when using Pangraf 0.25 Capsule during breastfeeding. Limited data indicates potential harm to the baby via breastmilk.
Age above 75(Geriatrics)
Age below 6 months(Pediatrics)
Consumption warning before consuming Pangraf 0.25 Capsule
Before consuming Pangraf 0.25 Capsule, it is essential to inform your doctor about any allergies to Tacrolimus or other medications. Pregnant or breastfeeding women should consult a doctor before using this medication. Avoid alcohol while taking Pangraf 0.25 Capsule. Only drive if fully alert, as it may affect vision or cause nervous disturbances in some individuals. Notify your doctor if you are due for a vaccination before starting Pangraf 0.25 Capsule, as it may impact your immune system and increase infection or skin cancer risks. When outdoors, wear protective clothing and sunscreen while using this medication. To prepare the oral suspension, opt for glass or metal materials to avoid the granules sticking to plastic containers, ensuring the full dose for children. Take precaution not to inhale or allow skin or eye contact with the granules or prepared suspension. If accidental contact occurs, wash the area with soap and water or rinse eyes with plain water.
What if you forgot to take Pangraf 0.25 Capsule?
If you forget to take your Pangraf 0.25 Capsule, try to take it as soon as you remember. But if it's close to the time for your next dose, just skip the missed dose. It's important not to take a double dose to make up for the one you missed. Stick to your usual schedule.
What happens if you take overdose of Pangraf 0.25 Capsule?
In the event that you or someone else takes more than the prescribed amount of Tacrograf 0.25mg Capsule, it is crucial to seek prompt medical attention. Overdose symptoms may manifest as tremors, abnormal kidney function resulting in reduced or absent urine output, elevated blood pressure, leg swelling, and feelings of fatigue. It is important not to delay in contacting your doctor or visiting the nearest hospital if overdose is suspected.
Additional Information
Habit Forming | No |
Chemical Class | Macrolide Lactams |
Therapeutic Class | - |
Action Class | Immunosuppressant- Calcineurin inhibitors |
FAQs
Disclaimer
The information provided on this website is to the best of our abilities to ensure it is accurate, reliable, and reviewed by a team of professionals. It should not be used to diagnose, prevent, or cure any health problem. The information presented here is not intended to create a doctor-patient relationship or replace a registered medical practitioner's advice, diagnosis, or treatment. The absence or provision of any information or warning regarding any medicine should not be assumed as an implied or explicit assurance of safety or efficacy. We highly recommend consulting your registered medical practitioner for all queries or doubts related to your medical condition. Do not ignore professional medical advice or delay seeking it based on the content encountered on our website. We intend to support, not replace, the doctor-patient relationship.
₹154.38
Inclusive of all taxes
Content verified by

Dr. Archana Prabhakar
MBBS, M.Med (Family Medicine)
Last update on 01-Oct-2024