Otraliv 450mg Tablet SR

By Otraliv

Rx

10 Tablet SR in a Strip

Composition icon

Composition

Ursodeoxycholic Acid(450mg)

Manufacturer - Radicool Pharmaceutical Pvt Ltd icon

Manufacturer - Radicool Pharmaceutical Pvt Ltd

RZ-157 G/F, Tughlaqabad, near Okhla Phase-2 New Delhi-110062

Expires on or after icon

Expires on or after

July, 2025

About Otraliv 450mg Tablet SR

Otraliv 450mg Tablet SR is a medication used to dissolve certain gallstones and prevent their formation, as well as to address primary biliary cirrhosis, a liver disease. This tablet works by breaking down cholesterol that has turned into stones in the gallbladder, aiding in the dissolution of the stones. It is essential to swallow the Otraliv 450mg Tablet SR whole after a meal and with a glass of milk or water. The dosage depends on the specific condition being treated and the individual's body weight. To derive maximum benefit, it is crucial to take the medication regularly as prescribed, even if symptoms improve.

Common side effects of Otraliv 450mg Tablet SR may include abdominal pain, diarrhea, hair loss, itching, nausea, and rash, although not everyone experiences these side effects. Should any side effects persist or cause concern, it is advised to consult with a healthcare provider. Before starting this medication, inform your doctor about any inflammation of the gallbladder or bile ducts, frequent cramp-like pain in the upper abdomen, coughing up blood, or rapid weight gain. Otraliv 450mg Tablet SR may interact with other medications, affecting their efficacy, so it is essential to disclose all current medications to your doctor. Women should discontinue hormonal birth control pills, as they can increase gallstone production. During treatment with Otraliv 450mg Tablet SR, ultrasound scans and frequent blood tests may be necessary to monitor liver function.

Otraliv-450 SR Tablet 10's belongs to a group of medicines known as biliary or gallstone dissolution agents, used for treating conditions such as gallstones, primary biliary cholangitis, excess cholesterol in bile, and liver diseases in children over the age of 6 due to cystic fibrosis. This tablet contains ursodeoxycholic acid, a naturally occurring bile acid that helps reduce cholesterol production in the blood, facilitating the dissolution of gallbladder stones primarily composed of cholesterol. Additionally, Otraliv-450 SR Tablet 10's offers protection to liver cells from damage caused by toxic bile acids and enhances overall liver function.

It is recommended to take Otraliv-450 SR Tablet 10's with food for optimal efficacy. The duration for which this medication should be taken will be determined by your healthcare provider based on your medical condition. Some common side effects that may occur include abdominal discomfort, pain, diarrhea, nausea, rash, dizziness, indigestion, and weakness, most of which tend to resolve on their own over time. However, if these side effects persist, consulting with your doctor is advised. Prior to starting Otraliv-450 SR Tablet 10's, inform your doctor if you have certain health conditions such as variceal bleeding, ascites, liver encephalopathy, or liver disease. Pregnant or breastfeeding individuals should not take Otraliv-450 SR Tablet 10's unless prescribed by a doctor. It is also important to avoid consuming alcohol while on this medication to prevent increased drowsiness and potential liver damage. Regular communication with your doctor regarding your health status and any other medications being taken is crucial to avoid adverse effects.


Benefits

Otraliv 450mg Tablet SR offers various benefits in the treatment of certain liver conditions. For individuals with primary biliary cholangitis, a liver disease that worsens over time, this medication plays a crucial role in preventing or delaying liver damage. It is particularly effective when initiated in the early stages of the condition. Continuous use of Otraliv 450mg Tablet SR is usually necessary for long-term management. To enhance the medication's effectiveness and promote general health, patients are advised to quit smoking, maintain a healthy weight, and limit alcohol consumption.


Moreover, Otraliv 450mg Tablet SR is also beneficial in addressing gallbladder stones by reducing the production of cholesterol by the liver. By breaking down cholesterol that has accumulated into stones in the gallbladder, this medication aids in the dissolving process. Although it may take a few months for complete dissolution, consistent use as prescribed by a healthcare provider is essential for optimal results. By incorporating other medications and adopting certain lifestyle changes recommended by a medical professional, individuals can further lower their cholesterol levels and reduce the likelihood of developing gallstones.


How to use the Otraliv 450mg Tablet SR

When using Otraliv 450mg Tablet SR, always follow your doctor's instructions on dosage and duration. Swallow the tablet whole with a glass of water, and do not chew, crush, or break it. It is important to take Otraliv 450mg Tablet SR with food. If you are prescribed the dispersible tablet form, dissolve it in water as directed on the label and consume it immediately after mixing. For syrup, suspension, or drops, use the provided measuring cup, dosing syringe, or dropper, and shake the container well before each use.


It is crucial to take Otraliv 450mg Tablet SR exactly as prescribed, either with meals or directly after. Do not crush or chew the tablet or capsule, and for the dispersible tablet, follow the instructions for reconstitution before consumption. Your doctor will determine the correct dosage and duration based on factors like your age, weight, and the severity of your condition. To experience optimal results, continue taking Otraliv 450mg Tablet SR for the full duration as prescribed. If you feel that the medication's effects are too strong or too weak, consult your doctor for further guidance.


Uses of Otraliv 450mg Tablet SR

Otraliv 450mg Tablet SR is utilized for the treatment of primary biliary cirrhosis and gallbladder stones. It is beneficial for managing conditions like gallstones, primary biliary cholangitis, and biliary and liver diseases triggered by cystic fibrosis. This medication is specifically designed to address primary biliary cirrhosis (PBC) and gallstones that may not be visible on X-ray in individuals with a functioning gallbladder. Moreover, Otraliv 450mg Tablet SR is effective in treating liver disease associated with cystic fibrosis in children between the ages of 6 and 18 years.


What conditions Otraliv 450mg Tablet SR treats?

Otraliv 450mg Tablet SR is used in conditions like primary biliary cholangitis, gallbladder stones, and cystic fibrosis. Primary biliary cholangitis, a type of autoimmune disease, damages the bile ducts in the liver, leading to liver damage. Gallbladder stones form when there is excess cholesterol in the bile stored in the gallbladder, causing abdominal pain and other digestive issues. Cystic fibrosis is a hereditary disease that affects the digestive system and lungs by producing thick fluids that block the pancreas and lungs.


Should you consult a doctor?

Seek medical attention if you have an improper functioning of the gall bladder, calcified gallstones visible on x-ray, acute inflammation of the biliary tract or gall bladder, blockage of the cystic duct or common bile duct, or experience frequent cramp-like pains in the upper abdomen while taking Otraliv 450mg Tablet SR. It is crucial to consult a doctor before using this medication, especially in children with biliary atresia or poor bile flow post-surgery. The doctor will determine the appropriate dosage based on factors like weight, age, and medical condition. If you or your child experiences any of the mentioned conditions or symptoms, seeking medical advice is advised to ensure safe and effective use of Otraliv 450mg Tablet SR.


Side effects of Otraliv 450mg Tablet SR

When taking Otraliv 450mg Tablet SR, it is common to experience side effects that may not require medical attention and often resolve as your body gets used to the medication. These side effects include abdominal pain, diarrhea, hair loss, itching, nausea, and rash. Some users may also encounter abdominal discomfort, fever, cough, dizziness, indigestion, black or tarry stools, frequent and painful urination, weakness, and soft, loose stools. However, it is crucial to consult your doctor if these side effects persist or cause concern. Specifically, if you encounter persistent diarrhea, it is advised to stop taking Otraliv 450mg Tablet SR immediately and seek medical attention from your doctor. Remember that your doctor is the best person to guide you on how to manage any side effects you may experience.


Safety advice

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liver

Limited information is currently available regarding the use of Otraliv 450mg Tablet SR in individuals with liver disease. It is strongly advised to consult with your healthcare provider before starting this medication to ensure its safety and appropriateness for your specific liver condition. Please seek guidance from your doctor.

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kidney

There is limited information available on using Otraliv 450mg Tablet SR in patients with kidney disease. Please consult your doctor for guidance.

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alcohol

Otraliv 450mg Tablet SR can make you very sleepy if you consume alcohol. Be careful and avoid alcohol when taking this medicine.

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driving

Otraliv 450mg Tablet SR generally does not impact driving ability.

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pregnancy

Otraliv 450mg Tablet SR is considered safe during pregnancy based on limited human studies and animal studies showing minimal adverse effects on the baby's development.

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breastfeeding

Otraliv 450mg Tablet SR appears safe during breastfeeding based on limited human data indicating low risk to the baby.


Age above 75(Geriatrics)

Otraliv 450mg Tablet SR can be used in elderly patients. However, consult with your doctor before taking Otraliv 450mg Tablet SR.


Consumption warning before consuming Otraliv 450mg Tablet SR

Before consuming Otraliv 450mg Tablet SR, it is crucial to consider certain warnings. Do not take this medication if you are allergic to any of its components or if you have specific conditions such as inflammation of the gall bladder, blockage in bile ducts, gallstones, or ulcers in the stomach or duodenum. It is essential to inform your doctor if you have variceal bleeding, ascites, liver encephalopathy, or liver disease before taking Otraliv 450mg Tablet SR.


Consult your healthcare provider before using Otraliv 450mg Tablet SR alongside other medications as it may interact with antibiotics and antihypertensive agents, leading to varied effects. Additionally, avoid consuming alcohol while on this medication to prevent potential side effects like increased drowsiness and liver damage.


If you are pregnant or breastfeeding, refrain from using Otraliv 450mg Tablet SR unless prescribed by your doctor. This medication is suitable for children above 6 years only under medical supervision. Always keep your doctor informed about your health status and current medication to prevent any adverse reactions.


Disease interactions

When taking Otraliv 450mg Tablet SR, it is important to inform your doctor if you have certain medical conditions such as biliary obstruction, liver impairment, variceal bleeding, ascites, or liver encephalopathy. These conditions could potentially interact with the medication and affect its effectiveness or safety. Biliary obstruction and liver impairment can impact how your body processes the drug, while variceal bleeding, ascites, and liver encephalopathy may alter how the medication works in your body. Therefore, it is crucial to disclose these health issues to your healthcare provider before starting Otraliv 450mg Tablet SR to ensure proper management and monitoring of any potential interactions.


What if you forgot to take Otraliv 450mg Tablet SR?

If you forget to take a dose of Otraliv 450mg Tablet SR, simply skip the missed dose and carry on with your regular dosing schedule. It is important not to take a double dose to make up for the missed one. Just continue taking your medication as prescribed at the next scheduled time. It is essential to try to take your doses on time to ensure the effectiveness of the medication in managing your condition. If you have any concerns about missed doses or how to best manage them, consult with your healthcare provider for guidance.


What happens if you take overdose of Otraliv 450mg Tablet SR?

Overdose of Otraliv 450mg Tablet SR can lead to harmful effects. If you or someone takes more than the recommended amount, it is essential to seek medical help without delay. The main symptom of an overdose is diarrhea. If you notice any signs of overdose, contact your doctor right away or go to the nearest hospital for immediate assistance. It is important to be cautious and seek help promptly in case of an overdose to prevent any complications.


Related lab tests

Related Lab Tests for Otraliv 450mg Tablet SR include Liver Function Test, Complete Blood Count, and Gall Bladder Scan. Liver Function Test checks how well the liver is working by measuring enzymes, proteins, and other substances in the blood. Complete Blood Count gives information about different blood cells like red blood cells, white blood cells, and platelets. Gall Bladder Scan is a test to check the functioning of the gallbladder and detect any gallstones or blockages. These lab tests are important to monitor the effects of Otraliv 450mg Tablet SR on the liver, blood, and gallbladder.


Additional Information

Habit FormingNo
Chemical ClassBile Acids and Salts
Therapeutic ClassGASTRO INTESTINAL
Action ClassHepatoprotectives

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Disclaimer

The information provided on this website is to the best of our abilities to ensure it is accurate, reliable, and reviewed by a team of professionals. It should not be used to diagnose, prevent, or cure any health problem. The information presented here is not intended to create a doctor-patient relationship or replace a registered medical practitioner's advice, diagnosis, or treatment. The absence or provision of any information or warning regarding any medicine should not be assumed as an implied or explicit assurance of safety or efficacy. We highly recommend consulting your registered medical practitioner for all queries or doubts related to your medical condition. Do not ignore professional medical advice or delay seeking it based on the content encountered on our website. We intend to support, not replace, the doctor-patient relationship.

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Dr. Archana Prabhakar

MBBS, M.Med (Family Medicine)

Last update on 01-Oct-2024