Onglyza 5mg Tablet
By Onglyza
Rx
14 Tablet in a Strip

Composition
Saxagliptin(5mg)

Manufacturer - AstraZeneca
Corporate & Registered Office, Block N1, 12th Floor, Manyata Embassy Business Park, Rachenahalli, Outer Ring Road, 560045, Bangalore

Expires on or after
August, 2025
About Onglyza 5mg Tablet
Onglyza 5mg Tablet is a medication used to treat type 2 diabetes mellitus in adults aged 18 years and older. It contains Saxagliptin, classified as a Dipeptidyl peptidase-4 (DPP-4) inhibitor. This drug is prescribed when diet and exercise alone are not enough to control blood sugar levels. Insulin, a hormone that regulates blood sugar levels, may not be produced adequately or may not function effectively in individuals with type 2 diabetes.
Onglyza 5mg Tablet works by blocking the enzyme DPP-4, which normally breaks down the hormone 'Incretin'. Incretins help to regulate insulin production only when necessary and reduce liver-induced blood sugar levels when not needed. This medicine is not suitable for patients with type 1 diabetes or for treating diabetic ketoacidosis. When taking Onglyza 5mg Tablet, it is important to follow your doctor’s advice on dosing and timing for optimal results.
Common side effects of Onglyza 5mg Tablet include low blood glucose levels (hypoglycemia), upper respiratory tract infections, headaches, and nasopharyngitis. Prolonged use of this medication can lead to acute pancreatitis and kidney issues. There is an increased risk of hypoglycemia when Onglyza 5mg Tablet is combined with other anti-diabetic drugs or insulin therapy, requiring possible dose adjustments.
Patients with a history of kidney disease, heart issues, or significant alcohol consumption should inform their doctor before starting Onglyza 5mg Tablet. Pregnant or breastfeeding women should consult their healthcare provider before using this medication. It is also crucial to disclose all other medications being taken to avoid potential interactions. Regular monitoring of kidney function and blood glucose levels may be necessary to ensure the drug is working effectively.
Overall, Onglyza 5mg Tablet is a valuable treatment option for individuals with type 2 diabetes, offering a way to help control blood sugar levels and reduce the risk of serious complications associated with the disease.
Benefits
Onglyza 5mg Tablet offers several benefits for individuals with Type 2 diabetes mellitus. As a DPP-4 inhibitor, this medication helps to regulate blood glucose levels by increasing the amount of insulin produced by the body after a meal. By preventing the release of excessive glucose into the bloodstream, Onglyza 5mg Tablet effectively lowers blood sugar levels. This plays a crucial role in managing diabetes and reducing the risk of complications such as kidney damage, blindness, and limb loss. Furthermore, Onglyza 5mg Tablet aids in preventing serious diabetes-related issues like retinopathy, nephropathy, neuropathy, diabetic foot ulcers, and delayed wound healing by controlling blood sugar levels effectively.
By blocking the action of DPP-4, the enzyme that breaks down 'Incretin' hormones, Onglyza 5mg Tablet ensures that the body produces insulin only as needed. This mechanism helps in maintaining stable blood sugar levels and reducing the sugar produced by the liver unnecessarily. Taking Onglyza 5mg Tablet regularly, in combination with a balanced diet and exercise regimen, is essential for long-term benefits. When used as prescribed, Onglyza 5mg Tablet enhances the overall quality of life for individuals with Type 2 diabetes, enabling them to lead a normal, healthy lifestyle while minimizing the risk of heart disease and stroke. It is crucial to adhere to the prescribed treatment plan to effectively manage diabetes and experience the full benefits of Onglyza 5mg Tablet in the long run.
How to use the Onglyza 5mg Tablet
To use Onglyza 5mg Tablet properly, it is essential to follow your doctor's instructions carefully. Take the medicine exactly as prescribed, in the dose and duration recommended by your doctor. Swallow the tablet whole with a glass of water; do not crush, chew, or break it. While Onglyza 5mg Tablet can be taken with or without food, it is advisable to take it at the same time each day for best results. Your physician will determine the right dosage and duration based on factors such as your age, body weight, and the specific condition being treated. If you have any questions or concerns about how to use Onglyza 5mg Tablet, do not hesitate to consult your healthcare provider for guidance.
Uses of Onglyza 5mg Tablet
Onglyza 5mg Tablet is primarily used in the treatment of Type 2 diabetes mellitus, a condition also known as non-insulin dependent diabetes. It is specifically designed to help manage and control the symptoms of type 2 diabetes. By effectively regulating blood sugar levels, Onglyza 5mg Tablet plays a crucial role in the treatment and management of this chronic condition. It is an essential tool for individuals seeking to effectively manage their type 2 diabetes and improve their overall quality of life.
What conditions Onglyza 5mg Tablet treats?
Type 2 diabetes occurs when the body cannot produce enough insulin or when the insulin it produces is not effective. This leads to high blood sugar levels, causing symptoms like increased thirst, frequent urination, fatigue, and blurred vision. In some instances, weight gain may occur, while in rare cases weight loss is possible. Complications of type 2 diabetes can include nerve problems, kidney issues, eye damage or blindness, limb amputation, sexual dysfunction, and a higher risk of heart attack or stroke.
Should you consult a doctor?
It is important to seek medical advice before taking Onglyza 5mg Tablet if you have type 1 diabetes, diabetic ketoacidosis, diabetic pre-coma, or diabetic coma. This medication is not suitable for individuals with hereditary diseases, galactose intolerance, lapp lactase deficiency, or glucose-galactose malabsorption.
Additionally, you should inform your doctor before using Onglyza 5mg Tablet if you have a condition that weakens your immune system, such as AIDS, or if you are taking medications following an organ transplant. It is also crucial to disclose any history of pancreatitis or if you are experiencing elevated stress levels due to factors like fever, infection, surgery, or trauma.
Seek medical attention promptly if you experience any of these conditions to ensure the safe and proper use of Onglyza 5mg Tablet.
Side effects of Onglyza 5mg Tablet
Onglyza 5mg Tablet may cause some side effects, but most of them typically fade away as your body gets used to the medicine. However, if you experience persistent side effects or have concerns, it's best to consult your doctor. Some common side effects of Onglyza 5mg Tablet include hypoglycemia (low blood sugar level) when used in combination with insulin or sulfonylurea, upper respiratory tract infections, urinary tract infections, headaches, and peripheral edema. Hypoglycemia can lead to low blood glucose levels, so it's crucial to monitor your blood sugar levels carefully.
Additionally, users of Onglyza 5mg Tablet have reported experiencing symptoms such as dizziness, diarrhea, and stomach pain. Upper respiratory tract infections and urinary tract infections are also potential side effects. Nasopharyngitis, an infection of the nose and throat commonly associated with the common cold, is another side effect observed in some individuals. If you notice any of these side effects, consult your healthcare provider for proper guidance and monitoring.
Safety advice

liver
Onglyza 5mg Tablet can be used safely in patients with liver disease. It is not necessary to adjust the dose of Onglyza 5mg Tablet based on liver function.

kidney
Onglyza 5mg Tablet requires caution in patients with kidney disease. Consult your doctor for possible dose adjustment and regular kidney function test monitoring.

alcohol
It is advised not to drink alcohol while taking Onglyza 5mg Tablet.

driving
To ensure safety while driving, avoid driving if you experience symptoms of low or high blood sugar when taking Onglyza 5mg Tablet. Your ability to drive can be affected by these symptoms.

pregnancy
Onglyza 5mg Tablet is usually safe for use during pregnancy. Animal studies indicate minimal harm to the baby, but human studies are limited.

breastfeeding
Onglyza 5mg Tablet may not be safe to use while breastfeeding. Limited information indicates it could pass into breastmilk and pose a risk to the baby.
Age below 6 months(Pediatrics)
Onglyza 5mg Tablet is not recommended for use in children and adolescents under 18 years of age. Consult your doctor before taking it.
Consumption warning before consuming Onglyza 5mg Tablet
Before consuming Onglyza 5mg Tablet, it's important to be aware of some crucial warnings. There is a heightened risk of experiencing low blood sugar levels (hypoglycemia) when Onglyza 5mg Tablet is combined with other anti-diabetic medications or insulin. In such cases, your doctor may need to adjust the dosage of Onglyza 5mg Tablet. Prolonged use of this medication may lead to acute pancreatitis (swollen pancreas) and severe kidney issues. Additionally, some patients may be at risk of severe allergic reactions such as anaphylaxis, angioedema (skin swelling), and skin conditions like Stevens-Johnson syndrome when taking Onglyza 5mg Tablet. It's crucial to note that the safety and effectiveness of Onglyza 5mg Tablet in children under 18 years old have not been established, and therefore it should not be given to them. Patients who are on digoxin (a heart medication) alongside Onglyza 5mg Tablet must be closely monitored due to potential severe drug interactions that have been observed.
What if you forgot to take Onglyza 5mg Tablet?
If you forget to take your scheduled dose of Onglyza 5mg Tablet, try to take it as soon as you remember. But if it's close to the time for your next dose, it's best to skip the missed one and continue with your regular dosing schedule. Avoid taking a double dose to make up for the missed one. It's important to maintain consistency with your Onglyza 5mg Tablet medication to ensure its effectiveness in managing your condition.
What happens if you take overdose of Onglyza 5mg Tablet?
Overdose is a serious situation that can occur if too much Onglyza 5mg Tablet is taken. In case of an overdose, it is important to seek immediate help from a doctor or go to the nearest hospital. Accidentally using more than the recommended dose can lead to harmful effects on the body. It is crucial to act quickly and get medical attention to address any potential risks associated with an overdose of Onglyza 5mg Tablet.
Related lab tests
Related Lab Tests for monitoring the effects of Onglyza 5mg Tablet include Glucose - Fasting Blood, Glucose - Postprandial Blood, and Glycosylated Hemoglobin tests. These tests help healthcare providers assess how well the medication is working to control blood sugar levels in patients. The Glucose - Fasting Blood test measures blood sugar levels after a period of fasting, usually overnight, providing a baseline level. The Glucose - Postprandial Blood test measures blood sugar levels after a meal, giving insight into how the body processes sugar after eating. The Glycosylated Hemoglobin test, also known as the A1c test, provides an average of blood sugar levels over the past 2-3 months, offering a longer-term view of blood sugar control. Monitoring these lab tests helps ensure that Onglyza 5mg Tablet is effectively managing blood sugar levels in individuals with diabetes.
Additional Information
Habit Forming | No |
Chemical Class | Alpha amino acid amides |
Therapeutic Class | ANTI DIABETIC |
Action Class | - |
FAQs
Disclaimer
The information provided on this website is to the best of our abilities to ensure it is accurate, reliable, and reviewed by a team of professionals. It should not be used to diagnose, prevent, or cure any health problem. The information presented here is not intended to create a doctor-patient relationship or replace a registered medical practitioner's advice, diagnosis, or treatment. The absence or provision of any information or warning regarding any medicine should not be assumed as an implied or explicit assurance of safety or efficacy. We highly recommend consulting your registered medical practitioner for all queries or doubts related to your medical condition. Do not ignore professional medical advice or delay seeking it based on the content encountered on our website. We intend to support, not replace, the doctor-patient relationship.
₹665.5
Inclusive of all taxes
Content verified by

Dr. Archana Prabhakar
MBBS, M.Med (Family Medicine)
Last update on 01-Oct-2024