Natzold Infusion

By Natzold

Rx

100ml Infusion in a Vial

Composition icon

Composition

Zoledronic acid(5mg/100ml)

Manufacturer - Natco Pharma Ltd icon

Manufacturer - Natco Pharma Ltd

Natco House, Road No.2, Banjara Hills, Hyderabad-500 034, India

Expires on or after icon

Expires on or after

April, 2026

About Natzold Infusion

Natzold Infusion, containing Zoledronic Acid, falls under the group of medicines known as Bisphosphonates. This infusion is primarily used in post-menopausal women and adult men for managing osteoporosis, which is a condition where bones weaken, often due to factors like menopause or corticosteroid treatment. It is also prescribed for Paget’s disease of the bone in adults.

Osteoporosis is a bone disease that arises when bone mineral density decreases or the structure of bone is altered. It is commonly seen in women post-menopause and can also affect adult men. On the other hand, Paget's disease of the bone is a chronic disorder that interrupts the normal bone renewal process, leading to weakened and potentially deformed bones.

If you are prescribed Natzold Infusion, your healthcare provider may suggest making lifestyle adjustments such as following a balanced diet rich in calcium and vitamin D. Before starting treatment with Natzold Infusion, diagnostic tests may be recommended to assess your current condition.

This infusion is not suitable for patients with severe kidney problems or low levels of calcium in the blood. Pregnant and breastfeeding women should avoid taking Natzold Infusion without consulting their doctor first. It is also not meant for use in children and adolescents (below 18 years) and should be used cautiously in elderly patients.

When undergoing treatment with Natzold Infusion, you may experience common side effects like headache, dizziness, vomiting, diarrhea, fever, and various types of pain in muscles, joints, or bones. If any of these symptoms worsen, it is important to inform your doctor promptly.

Remember, Natzold Infusion is just one part of a comprehensive treatment program that may include dietary modifications and the intake of calcium and vitamin supplements. Before starting this medication, inform your doctor about any existing kidney problems, low calcium levels, or other medications you are currently taking. Regular medical tests may be required to monitor kidney function and calcium levels. Additionally, avoiding smoking and excessive alcohol consumption is crucial to help maintain bone health.


Benefits

Natzold Infusion is a powerful medication that offers various benefits for individuals dealing with osteoporosis and hypercalcemia. For those suffering from osteoporosis, a condition that leads to weaker and more fragile bones, Natzold Infusion serves as a valuable treatment option. As a bisphosphonate medication, it works by slowing down the breakdown of bone in the body, thereby maintaining bone density and lowering the risk of fractures. Administered once a year for osteoporosis treatment and every two years for prevention, Natzold Infusion is an effective way to enhance bone strength and reduce the likelihood of bone injuries.


Moreover, in cases of hypercalcemia, a serious condition characterized by excessive calcium in the blood, Natzold Infusion acts as a crucial treatment method. By inhibiting the rate at which bone breakdown occurs in the body, this medication helps lower the calcium levels in the blood. This is particularly beneficial for individuals with cancer-related hypercalcemia, where elevated calcium levels can pose significant health risks. Natzold Infusion works by binding tightly to the bone, preventing osteoclasts from removing calcium and thus supporting bone strength. Additionally, it hinders the reabsorption of calcium from bones into the bloodstream, aiding in the management of high blood calcium levels caused by cancer.


In summary, Natzold Infusion offers a dual benefit of strengthening bones and regulating calcium levels, making it a valuable treatment option for individuals grappling with osteoporosis and hypercalcemia. By following the recommended dosage and incorporating healthy habits such as exercise and balanced nutrition, patients can maximize the positive outcomes of Natzold Infusion and improve their overall bone health.


How to use the Natzold Infusion

To use Natzold Infusion, you need to have a healthcare professional administer it. This medicine comes in the form of a 100 ml infusion with a strength of 5 mg. It is crucial that you do not try to administer this medication yourself. Your doctor or nurse will be responsible for giving you the infusion, so it is important to follow their instructions carefully. Do not attempt to self-administer Natzold Infusion to ensure safety and proper dosage. Always rely on the expertise of healthcare professionals when using this medication.


Uses of Natzold Infusion

Natzold Infusion is used to treat various conditions such as osteoporosis in postmenopausal women, Paget’s disease, and hypercalcemia associated with cancer. Osteoporosis is a condition characterized by weak and brittle bones, especially common in women after menopause. Paget's disease is a chronic bone disorder that can result in enlarged and misshapen bones. Hypercalcemia, which is having high levels of calcium in the blood, can occur in individuals with certain types of cancer. Natzold Infusion is beneficial in managing these conditions effectively.


What conditions Natzold Infusion treats?

Osteoporosis is a bone disease that weakens bones by reducing bone density. Post-menopausal women are more at risk as their estrogen levels decrease after menopause, causing bone loss. Long-term use of steroids can also lead to osteoporosis. Symptoms include back pain, loss of height, stooped posture, and bones breaking easily. Paget's disease involves quick but disordered bone remodeling, leading to weakened bones. Hypercalcemia in cancer, seen in breast, lung, or blood cancer, results in high blood calcium levels causing symptoms like nausea and loss of appetite.


Should you consult a doctor?

If you experience serious side effects of Natzold Infusion such as kidney problems, low calcium levels in the blood, or pain in the mouth or jaw, you should seek urgent medical attention. These are signs that need immediate care. Additionally, if you are pregnant or breastfeeding, do not take this medication and consult your doctor. Inform your healthcare provider if you have kidney issues, low calcium levels, or are taking other medications. It is important to notify your doctor about any alarming symptoms you may encounter while taking Natzold Infusion. Remember, avoiding dehydration, smoking, and excessive alcohol consumption is crucial for maintaining bone health and ensuring the effectiveness of the treatment. If mild side effects like headache, back pain, heartburn, or diarrhea persist or cause worry, do consult your doctor for guidance. Your healthcare provider can offer support and advice to address any concerns you may have during your Natzold Infusion treatment.


Side effects of Natzold Infusion

When undergoing Natzold Infusion, some individuals may experience mild side effects that typically do not necessitate medical intervention and tend to fade as the body becomes accustomed to the medication. These side effects could include headaches, back pain, musculoskeletal pain (affecting bones, muscles, or joints), heartburn, diarrhea, nausea, breathlessness, fatigue, constipation, bone pain, vomiting, fever, and anemia (characterized by a low count of red blood cells). Other possible side effects may encompass dizziness, flu-like symptoms such as chills, tiredness, muscle, and joint pain, as well as pain in muscles, joints, or bones. Additionally, individuals might observe swelling or experience pain at the site of infusion. It is advisable to consult a healthcare provider if these side effects persist or cause concern.


Safety advice

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liver

Limited information is available regarding the use of Natzold Infusion in patients with liver disease. It is important to consult with your doctor before using this medication to ensure it is safe for your specific condition.

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kidney

Limited data exists on Natzold Infusion use for kidney disease. Consult your doctor for guidance.

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alcohol

When taking Natzold Infusion, be cautious about consuming alcohol. It's advisable to consult your doctor before doing so.

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driving

While using Natzold Infusion, be cautious about driving as it can reduce alertness, impact vision, and cause drowsiness or dizziness. Avoid driving if you experience these symptoms.

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pregnancy

Natzold Infusion should not be used during pregnancy, as there is clear evidence of harm to the unborn baby. Only in severe, life-threatening cases would a doctor consider its use after weighing the risks against the benefits. Consult your doctor before use.

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breastfeeding

Natzold Infusion is not recommended for use during breastfeeding, as limited human data indicates a risk of the drug passing into breastmilk and potentially harming the baby.


Consumption warning before consuming Natzold Infusion

Before consuming Natzold Infusion, it is crucial to be aware of certain warnings. Inform your doctor if you are allergic to Natzold Infusion or any other medications. Pregnant or breastfeeding individuals should avoid this infusion without consulting a doctor. Children under 18 years should not take this medication due to uncertain safety and effectiveness. Individuals with hypocalcemia, severe kidney problems, or those prone to dizziness should steer clear of Natzold Infusion. Smoking patients must inform their doctor beforehand, as dental risks may increase. Be vigilant for signs of osteonecrosis of the jaw (ONJ) such as loose teeth, swelling, or pain in the mouth, and promptly consult your doctor and dentist if any occur. To prevent dehydration, drink at least 2 glasses of fluids before and after treatment, and take calcium and vitamin D supplements as prescribed.


What if you forgot to take Natzold Infusion?

If you forget to take a dose of Natzold Infusion, it's important to seek guidance from your doctor. Ensuring you follow your prescribed dosage is essential for the effectiveness of the treatment. Consulting with your healthcare provider will help you determine the best course of action to make up for the missed dose and maintain the intended treatment schedule. Your doctor will provide you with specific instructions tailored to your situation to ensure that the treatment remains on track.


Related lab tests

When monitoring the effects of Natzold Infusion, it's important to conduct certain related lab tests to ensure that the treatment is working as expected. Two key tests to consider are calcium levels and intact parathyroid hormone levels. Calcium levels help determine the amount of calcium in the blood, which is essential for various bodily functions including bone health and muscle contractions. Intact parathyroid hormone levels indicate how well the parathyroid glands are functioning, which play a crucial role in regulating calcium levels in the body. Monitoring these lab tests can provide valuable information on the efficacy of Natzold Infusion and guide treatment decisions.


Additional Information

Habit FormingNo
Chemical ClassBisphosphonate Derivative
Therapeutic ClassPAIN ANALGESICS
Action ClassBone resorption inhibitor -Bisphosphonates

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Disclaimer

The information provided on this website is to the best of our abilities to ensure it is accurate, reliable, and reviewed by a team of professionals. It should not be used to diagnose, prevent, or cure any health problem. The information presented here is not intended to create a doctor-patient relationship or replace a registered medical practitioner's advice, diagnosis, or treatment. The absence or provision of any information or warning regarding any medicine should not be assumed as an implied or explicit assurance of safety or efficacy. We highly recommend consulting your registered medical practitioner for all queries or doubts related to your medical condition. Do not ignore professional medical advice or delay seeking it based on the content encountered on our website. We intend to support, not replace, the doctor-patient relationship.

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Dr. Archana Prabhakar

MBBS, M.Med (Family Medicine)

Last update on 01-Oct-2024