Mexate 15 Tablet

By Mexate

Rx

4 Tablet in a Strip

Composition icon

Composition

Methotrexate(15mg)

Manufacturer - Zydus Cadila icon

Manufacturer - Zydus Cadila

Zydus Tower, Satellite Cross Roads,Ahmedabad – 380015 Gujarat, India.

Expires on or after icon

Expires on or after

January, 2027

About Mexate 15 Tablet

Mexate 15 Tablet is a medication categorized as an anti-metabolite and immunosuppressant. It is commonly prescribed for the treatment of cancer affecting various parts of the body such as breasts, head, neck, lungs, blood, bone, lymph, and uterus. Additionally, Mexate 15 Tablet is used to manage conditions like rheumatoid arthritis, severe and uncontrolled psoriasis, and Crohn’s disease. The active ingredient in Mexate 15 Tablet is Methotrexate, which functions by interrupting the immune system processes causing inflammation in joint tissues, thus reducing pain and inflammation. This medication also helps in preventing the growth of cancer cells, which aids in the treatment of cancer.

Mexate 15 Tablet should be taken as per the doctor's instructions to avoid serious side effects. Patients may not notice immediate benefits as it can take several weeks or even months for the medication to show full effects. It is important not to discontinue the treatment without consulting the doctor. Consumption of alcohol while on Mexate 15 Tablet is not recommended as it can increase the risk of liver damage.

Common side effects associated with Mexate 15 Tablet include ulcerative stomatitis, hair loss, low blood cell count, increased liver enzymes, nausea, and abdominal distress. Patients may be advised to take folic acid to alleviate some of these side effects. If side effects persist or worsen, it is essential to inform the doctor. Mexate 15 Tablet may also lower the body's ability to fight infections and impact blood, liver, or kidney function. To monitor for these effects, doctors may conduct various tests such as blood tests, X-rays, and physical examinations before and during treatment with Mexate 15 Tablet.

Before starting Mexate 15 Tablet, patients should inform their doctor about any existing stomach, liver, or kidney issues, as well as any ongoing medications for infections. Mexate 15 Tablet may interact with other medications, so it is crucial to communicate all current medications to the healthcare team. Pregnant or breastfeeding women are advised against using Mexate 15 Tablet as it may harm the baby. It is important to have regular discussions with the healthcare provider to manage potential side effects and interactions with Mexate 15 Tablet effectively.


Benefits

Mexate 15 Tablet offers various benefits in treating different conditions. When used in cancer treatment, it helps slow down the growth of cancer cells, making it effective in combating acute leukemias, non-Hodgkin’s lymphoma, and various solid tumors such as those found in breast, lung, bladder, head and neck, as well as cervical, ovarian, and testicular cancer. This medication can be used alone or alongside other drugs to enhance its effectiveness. It is important to note that Mexate 15 Tablet is a potent and toxic medicine, so discussing the risks and benefits with a healthcare provider is crucial. During treatment with Mexate 15 Tablet, it is advisable to refrain from alcohol consumption and maintain proper hydration by drinking plenty of water.


In cases of rheumatoid arthritis, Mexate 15 Tablet, categorized as an antimetabolite, can be used for severe rheumatoid arthritis that has not responded to other treatments. By suppressing the body's immune system, this medication helps reduce swelling, pain, stiffness, and improves joint function. Adhering to the prescribed dosage and duration is key to maximizing the benefits of Mexate 15 Tablet, which may take several months to achieve full effectiveness.


Furthermore, in the treatment of psoriasis, Mexate 15 Tablet, also classified as an antimetabolite, is recommended for severe cases where previous treatments have not provided relief. Psoriasis is a skin condition characterized by rapid growth of skin cells, and Mexate 15 Tablet works by targeting and eliminating these fast-growing cells. Similar to its usage in rheumatoid arthritis, strict adherence to the prescribed regimen is essential for optimal results. It is important to avoid alcohol intake during treatment with Mexate 15 Tablet and stay hydrated by drinking an adequate amount of water.


Additionally, Mexate 15 Tablet is beneficial in addressing Crohn's disease, a chronic inflammatory condition affecting the intestines. Common symptoms include abdominal pain and diarrhea, which Mexate 15 Tablet helps alleviate by reducing inflammation and preventing symptom recurrence. This medication plays a crucial role in managing the symptoms of Crohn's disease, offering relief to individuals dealing with this long-term condition.


How to use the Mexate 15 Tablet

To properly use Mexate 15 Tablet, it is important to follow your doctor's instructions regarding the dosage and duration of treatment. Always swallow the tablet whole with a glass of water; do not chew, crush, or break it. You can take Mexate 15 Tablet with or without food, but try to take it at the same time each day for consistency. Your physician will determine the appropriate dose and duration based on factors like your age, body weight, and the specific condition being treated. It is crucial to adhere to the prescribed guidelines to ensure the medication works effectively. If you are prescribed Mexate 15 Tablet, remember to take it exactly as instructed by your doctor. Swallow the tablet/capsule whole with water, either one hour after food in the evening or as directed by your healthcare provider. For the oral solution, use the dosing syringe to take the specified amount by mouth. By following these instructions closely, you can maximize the benefits of Mexate 15 Tablet and manage your health condition more effectively.


Uses of Mexate 15 Tablet

Mexate 15 Tablet is used in the treatment of various conditions including cancer, rheumatoid arthritis, psoriasis, and Crohn’s disease. It is beneficial for patients with active rheumatoid arthritis, psoriasis, and arthritis associated with psoriasis (psoriatic arthritis). Additionally, Mexate 15 Tablet can be effective for treating relapsed and refractory Non-Hodgkin’s Lymphoma and polyarticular juvenile idiopathic arthritis. This medication plays a vital role in managing these medical conditions and improving the overall well-being of patients.


What conditions Mexate 15 Tablet treats?

Mexate 15 Tablet is used in treating autoimmune conditions such as rheumatoid arthritis, characterized by joint pain and inflammation. It is also effective for psoriatic arthritis, found in patients with or without psoriasis. Psoriatic arthritis affects large joints and extremities, causing joint inflammation, mobility issues, and skin symptoms. Additionally, Mexate 15 Tablet can help manage psoriasis, a chronic skin condition leading to rapid skin cell growth, red patches, and itching. This medication is also used in addressing cancer, a condition where cells divide uncontrollably.


Should you consult a doctor?

It is important to seek medical advice before taking Mexate 15 Tablet if you have certain health conditions. Avoid using this medication if you have bone marrow disorders, blood disorders, weakened immune system, existing severe infections like tuberculosis or HIV, ulcers in the gastrointestinal tract, mouth inflammation or ulcers, and if you are receiving live vaccines. Inform your doctor if you have diabetes, are overweight, experiencing diarrhea, ulcers in the colon, undergoing radiotherapy, folate deficiency, lactose or galactose intolerance, or have mental illness. Consulting with your healthcare provider is crucial to ensure the safe and appropriate use of Mexate 15 Tablet.


Side effects of Mexate 15 Tablet

When taking Mexate 15 Tablet Tablets, you may experience some side effects as your body gets used to the medication. These side effects are usually not serious and may go away on their own. However, if these side effects persist or you are concerned about them, it is important to consult your doctor. Common side effects of Mexate 15 Tablet Tablets include ulcerative stomatitis, nausea, abdominal pain, increased liver enzymes, hair loss, and decreased blood cells such as red cells, white cells, and platelets.


Other possible side effects that may occur with Mexate 15 Tablet Tablets include nausea, vomiting, diarrhea, unusual fatigue, dizziness, headache, loss of appetite, elevated liver enzymes, lowered resistance to infections, tingling sensation, leukopenia (decreased white blood cells), soreness of mouth and lips, fever, general deterioration of the body, local infections, anemia, reduced blood clotting, altered blood count, swelling of lymph nodes, inflammation and ulcers in the vagina, decreased serum albumin levels, increased skin pigmentation, viral skin infections like herpes, joint or muscle pain, bladder inflammation and ulcers, fatty liver, chills, fits, light sensitivity, brown skin pigmentation, increase in rheumatic nodules, psoriasis-related lesions pain, sore throat, reduced appetite, and skin rash with reddening.


In rare cases, serious side effects may occur with Mexate 15 Tablet Tablets. Seek immediate medical attention if you experience scar tissue formation in the lungs, severe allergic reactions with chest tightness and difficulty breathing, toxic skin reactions like Stevens-Johnson Syndrome, decreased white blood cells with fever and deterioration, painful urination, kidney damage, liver inflammation or damage, stomach ulcers or bleeding, blood clot formation, decreased urine formation, seizures, blood in urine, brain disorders, tendency to bleed or bruise easily, loss of coordination or speech, weakness or paralysis on one side of the body, miscarriage or fetal damage in women. It is crucial to stop taking Mexate 15 Tablet Tablets and consult a doctor if any of these severe side effects are experienced.


Safety advice

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liver

When taking Mexate 15 Tablet, it's important to be cautious if you have liver disease. You may need a dose adjustment for this medication, so consulting your doctor is recommended to ensure it is used safely. If you have chronic liver disease or liver impairment, it is advisable to consult your doctor before using Mexate 15 Tablet.

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kidney

Mexate 15 Tablet requires caution in patients with kidney disease. Dose adjustment may be necessary, so consult your doctor. Regular kidney function tests are recommended during treatment. If you have kidney impairment, seek advice before using Mexate 15 Tablet.

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alcohol

It is unsafe to drink alcohol while using Mexate 15 Tablet. It is recommended to avoid alcohol when taking Mexate 15 Tablet to ensure safety.

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driving

Caution is advised when driving after taking Mexate 15 Tablet, as it may cause decreased alertness, vision changes, sleepiness, and dizziness. Refrain from driving if experiencing these effects.

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pregnancy

Mexate 15 Tablet is not safe for use during pregnancy. Studies suggest potential harm to the developing baby in pregnant women and animals. It is advised to consult your doctor before using this medication. Trexo 5 Tablet 10's may also cause birth defects and is not recommended during pregnancy.

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breastfeeding

Mexate 15 Tablet is not safe for breastfeeding mothers as it may harm the baby. Trexo 5 Tablet 10's can pass into breast milk, so avoid breastfeeding while using it.


Age above 75(Geriatrics)

Mexate 15 Tablet is recommended to be administered with caution and in a lower dosage to elders due to diminished function of the liver and kidneys and reduced folate levels in the blood in old age. Also, it is recommended to closely monitor the elderly, taking Mexate 15 Tablet for the identification of possible side effects. Consult the doctor before taking Mexate 15 Tablet.


Age below 6 months(Pediatrics)

Mexate 15 Tablet is not recommended in children for the management of psoriasis and rheumatoid arthritis. However, Mexate 15 Tablet can be used with caution in children to manage polyarticular juvenile idiopathic arthritis. Your doctor will prescribe the right dose depending on your child’s age, body weight, and health condition. Consult your doctor for advice before taking Mexate 15 Tablet.


Consumption warning before consuming Mexate 15 Tablet

Before consuming Mexate 15 Tablet, it is important to note certain warnings. Do not take this medication if you are allergic to any of its components or if you have specific health conditions such as immunodeficiency issues, bone marrow problems, low white blood cell count, or chronic liver disease. Avoid Mexate 15 Tablet if you are pregnant, breastfeeding, or have liver or kidney problems. Prior consultation with your doctor is essential if you have a history of stomach ulcers, diabetes, lung issues, or are due for vaccinations. It is crucial to follow your doctor's dosage instructions precisely to avoid potential serious effects. Be cautious as Mexate 15 Tablet can lead to dizziness and fatigue, impacting your ability to drive safely. Discontinue use and seek immediate medical attention if you experience symptoms like mouth sores, diarrhoea, fever, dehydration, or signs of infection.


Disease interactions

When taking Mexate 15 Tablet, it is crucial to inform your doctor if you have certain health conditions. This includes immunodeficiency issues, bone marrow problems, low white blood cell count, low platelet count, serious anaemia, liver problems from alcohol abuse, or chronic liver disease. It is important for your doctor to have this information to ensure the safe and effective use of Mexate 15 Tablet and to avoid any potential interactions with your existing health conditions.


What if you forgot to take Mexate 15 Tablet?

If you realize you missed a dose of Mexate 15 Tablet, try to take it as soon as you remember. But if it's close to the time for your next scheduled dose, it's better to just skip the missed one and continue with your usual dosing routine. It's important not to take a double dose of Mexate 15 Tablet to make up for the missed one. Taking extra medication can be harmful and may lead to unwanted side effects. Just carry on with your medication schedule as prescribed by your healthcare provider.


What happens if you take overdose of Mexate 15 Tablet?

If you take more than the prescribed amount of Mexate 15 Tablet, it's important to seek help from your doctor right away. Signs of overdose with Mexate 15 Tablet include increased bruising or bleeding, feeling nauseous, vomiting, and experiencing unusual weakness. In some cases, you may also notice the appearance of mouth sores and ulcers. It's crucial to act promptly if you suspect an overdose and consult with a healthcare professional for guidance and support.


Related lab tests

When taking Mexate 15 Tablet, it is important to monitor certain lab tests to ensure the medication is safe and effective for you. Your healthcare provider may recommend the following related lab tests:


1. Anti Saccharomyces Cerevisiae (ASCA), IgA: This test helps in diagnosing conditions related to the immune system and gastrointestinal tract.


2. Anti Saccharomyces Cerevisiae (ASCA), IgG: Another test to assess immune system function, particularly in relation to gastrointestinal disorders.


3. Rheumatoid Factor - Agglutination and Rheumatoid Factor - Turbidometry: These tests are used to detect and monitor autoimmune conditions like rheumatoid arthritis.


4. Rheumatoid Factor IgG Antibody: A specific antibody test to aid in the diagnosis and management of rheumatoid arthritis.


In addition to these specific tests, your healthcare provider may also recommend the following general lab tests to monitor your overall health while on Mexate 15 Tablet:


1. Complete Blood Count (CBC)/ Hemogram: This test provides information on different blood cell types and can help detect various conditions such as anemia or infections.


2. Liver Function Test (LFT): This test assesses the health of your liver and can detect liver disorders or monitor the effects of medications on liver function.


3. Kidney Function Test (KFT): A test to evaluate how well your kidneys are functioning and to monitor for any kidney-related issues.


Regular monitoring of these lab tests can help ensure that Mexate 15 Tablet is safe and effective for you. It is important to follow your healthcare provider's recommendations and attend scheduled lab tests to manage your health effectively.


Additional Information

Habit FormingNo
Chemical ClassGlutamic Acid Derivatives
Therapeutic ClassANTI NEOPLASTICS
Action ClassAntimetabolite- Methotrexate

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The information provided on this website is to the best of our abilities to ensure it is accurate, reliable, and reviewed by a team of professionals. It should not be used to diagnose, prevent, or cure any health problem. The information presented here is not intended to create a doctor-patient relationship or replace a registered medical practitioner's advice, diagnosis, or treatment. The absence or provision of any information or warning regarding any medicine should not be assumed as an implied or explicit assurance of safety or efficacy. We highly recommend consulting your registered medical practitioner for all queries or doubts related to your medical condition. Do not ignore professional medical advice or delay seeking it based on the content encountered on our website. We intend to support, not replace, the doctor-patient relationship.

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Dr. Abdul Rahman S

MBBS, MD - General Medicine

Last update on 01-Oct-2024