Mesacol CR 500mg Tablet
By Mesacol
Rx
10 Tablet PR in a Strip

Composition
Mesalazine(500mg)

Manufacturer - Sun Pharmaceutical Industries Ltd
Plot no 107/108,Namli block , Ranipool, East Sikkim 737135

Expires on or after
July, 2025
About Mesacol CR 500mg Tablet
Mesacol CR 500mg Tablet is an anti-inflammatory medication specifically designed to treat bowel conditions such as ulcerative colitis and Crohn's ileocolitis. Ulcerative colitis is a chronic inflammatory disease affecting the large intestine, leading to ulcers on the colon lining, which can cause symptoms like bleeding and stomach pain. Mesacol CR 500mg Tablet contains Mesalazine, which works by inhibiting the production of certain chemical substances that cause pain and swelling, thereby reducing inflammation in the intestines. It helps alleviate symptoms such as stomach pain and bleeding associated with these conditions.
It is crucial to follow your doctor's prescribed dosage instructions when taking Mesacol CR 500mg Tablet, typically alongside food for optimal absorption. Consistency in taking the medication as recommended is essential to prevent symptoms from returning or worsening. The common side effects of Mesacol CR 500mg Tablet may include nausea, diarrhea, stomach pain, headache, itching, flatulence, and vomiting. While most of these side effects do not require immediate medical attention and tend to resolve over time, it is important to consult your healthcare provider if they persist or worsen.
Before starting treatment with Mesacol CR 500mg Tablet, inform your doctor about any existing kidney or liver issues, as well as stomach blockages. Age can also be a determining factor in the suitability of this medication. Pregnant or breastfeeding individuals should consult their healthcare provider before initiating treatment. Furthermore, it is essential to disclose all other medications you are currently taking, as certain interactions may occur.
Individuals allergic to Mesalazine or with severe kidney/liver disease are advised against using Mesacol CR 500mg Tablet. For those experiencing severe symptoms such as stomach pain, cramps, headache, fever, or rash, it is recommended to discontinue the medication immediately and seek medical advice. Additionally, Mesacol CR 500mg Tablet is not recommended for children below a certain age, and caution should be exercised in elderly patients.
In summary, Mesacol CR 500mg Tablet is a medication belonging to the group of anti-inflammatory drugs used to treat ulcerative colitis and Crohn's disease by reducing inflammation in the intestines. Adhering to the prescribed dosage and guidelines, while being aware of potential side effects and contraindications, is crucial for the safe and effective use of this medication.
Benefits
Mesacol CR 500mg Tablet is a beneficial medication for individuals suffering from ulcerative colitis and Crohn’s disease. In ulcerative colitis, a condition characterized by inflammation in the large intestine and rectum leading to symptoms like bleeding, frequent diarrhea, and abdominal pain, Mesacol CR 500mg Tablet can provide relief from these uncomfortable symptoms and also aid in maintaining overall well-being by preventing their recurrence. It contains Mesalazine, an anti-inflammatory drug that works by reducing the production of pain-causing substances in the body, thereby alleviating inflammation in the intestines and offering relief from symptoms such as stomach pain and bleeding. This medication may also help in preventing future episodes of ulcerative colitis, making it a valuable treatment option for individuals dealing with this condition.
In Crohn’s disease, a chronic inflammatory condition of the intestines that commonly manifests through symptoms like diarrhea and abdominal pain, Mesacol CR 500mg Tablet plays a crucial role in managing the disease. By reducing inflammation in the intestines and relieving symptoms, this medication can significantly improve the quality of life for individuals with Crohn’s disease. Moreover, Mesacol CR 500mg Tablet is effective in preventing the recurrence of symptoms, offering long-term relief and stability for patients dealing with this challenging condition.
In conclusion, Mesacol CR 500mg Tablet provides multiple benefits for individuals suffering from ulcerative colitis and Crohn’s disease. Its anti-inflammatory properties, coupled with its ability to relieve symptoms and prevent future episodes of the diseases, make it a valuable and essential treatment option for those in need of effective management and relief from the discomfort associated with these conditions.
How to use the Mesacol CR 500mg Tablet
To use Mesacol CR 500mg Tablet, it’s important to follow the advice of your doctor or carefully read the label instructions. You can take the tablet with or without food, but it is recommended to take it at a fixed time for better results. When taking the tablet form, swallow it whole with a glass of water. Do not crush, chew, or break the tablet as it may affect its effectiveness. If you are using the granule form, empty the contents directly on your tongue and then drink some water or orange juice. You can also mix the granules with yogurt and consume it immediately without chewing. For the pellet form, refer to the label directions and take it as prescribed by your doctor.
If you have been prescribed the orally disintegrating tablet, place it in your mouth and allow it to dissolve completely without swallowing or chewing. Your doctor will determine the appropriate dosage and duration of Mesacol CR 500mg Tablet based on factors such as your age, weight, and medical condition. It is important to follow the instructions provided to ensure the medication works effectively in managing your condition.
Uses of Mesacol CR 500mg Tablet
Mesacol CR 500mg Tablet is effective in treating and preventing mild to moderate cases of ulcerative colitis and Crohn’s disease. It works by reducing the symptoms associated with ulcerative colitis, such as diarrhoea, rectal bleeding, and stomach pain that can affect individuals with this condition. By taking Mesacol CR 500mg Tablet as prescribed, patients can experience relief from these uncomfortable symptoms and manage their condition more effectively.
What conditions Mesacol CR 500mg Tablet treats?
Mesacol CR 500mg Tablet is used to treat conditions such as ulcerative colitis, a chronic inflammatory bowel disease that inflames the colon and causes ulcers. Symptoms may include bloody stools, stomach pain, diarrhoea, and weight loss. It can also lead to joint pain, mouth sores, and skin problems. Factors like immune disorders, environmental triggers, and genetic predisposition can contribute to ulcerative colitis. Crohn’s disease is another inflammatory bowel condition affecting the gastrointestinal tract with symptoms like blood in stools, stomach cramps, and fatigue.
Should you consult a doctor?
It is important to seek medical advice before taking Mesacol CR 500mg Tablet if you have a history of narrowing or blockage in your stomach or gut. This medication is not recommended for children and adolescents under 18 years old due to insufficient data on its safety and effectiveness in this age group. It is crucial to consult with a doctor before giving this medicine to a child. If you experience any discomfort or adverse reactions while taking Mesacol CR 500mg Tablet, it is advisable to seek guidance from a healthcare provider promptly.
Side effects of Mesacol CR 500mg Tablet
When taking Mesacol CR 500mg Tablet, some people may experience side effects. Most of these side effects are usually mild and temporary, as your body gets used to the medication. These may include stomach pain, flatulence (gas), headache, vomiting, diarrhea, nausea, and abdominal pain. In some cases, you might also notice symptoms like bleeding and bruising, feeling sleepy, trembling, muscle pain, hair loss, ear or throat pain, a racing heartbeat, or inflammation of the pancreas.
Other potential side effects could be rectal polyps, acne, swollen face, joint or back pain, changes in blood pressure, itching, rash, kidney failure, or increased sensitivity of your skin to sunlight. If you experience more severe reactions such as serious skin conditions like Stevens-Johnson syndrome, toxic epidermal necrolysis, acute intolerance syndrome with cramping and bloody stools, unexplained bruising, signs of allergic reaction, or increased pressure in the brain, it is important to discontinue the medication immediately and seek medical attention.
It's essential to consult your doctor if any side effects persist or if you have concerns about them. Your healthcare provider can provide guidance on how to manage these side effects or adjust your treatment if needed.
Safety advice

liver
It is important to exercise caution when using Mesacol CR 500mg Tablet in patients with liver disease. Adjusting the dosage of Mesacol CR 500mg Tablet may be necessary in such cases, hence it is advised to consult your doctor before starting the medication.

kidney
Mesacol CR 500mg Tablet should be used cautiously in patients with kidney disease. Dose adjustment may be necessary. Avoid use in severe kidney disease. Consult your doctor for guidance.

alcohol
Caution is necessary when consuming alcohol with Mesacol CR 500mg Tablet. It is advised to consult your doctor about alcohol intake.

driving
Mesacol CR 500mg Tablet typically does not impair driving abilities.

pregnancy
Mesacol CR 500mg Tablet may not be safe to use during pregnancy. Animal studies suggest potential harm to the developing baby. Please consult your doctor for a thorough evaluation of benefits and risks before using this medication.

breastfeeding
Mesacol CR 500mg Tablet should be used with caution during breastfeeding as it may not be safe. Limited data shows a potential for the drug to pass into breastmilk and harm the baby. Monitor the baby for diarrhea while taking this medication.
Age above 75(Geriatrics)
Mesacol CR 500mg Tablet should be used with caution in elderly patients (aged above 65 years). Consult your doctor before taking the medicine.
Consumption warning before consuming Mesacol CR 500mg Tablet
Before consuming Mesacol CR 500mg Tablet, ensure to inform your doctor of any allergies to Mesalazine or other medications. Caution is advised for the elderly. Pregnant or breastfeeding individuals should consult their doctor before taking Mesacol CR 500mg Tablet. It is not suitable for children under two years (tablets) or six years (granules) unless advised by a doctor. Avoid the tablet in cases of severe kidney failure. Serious skin reactions like toxic epidermal necrolysis or Stevens-Johnson syndrome may occur; seek medical attention if skin reactions appear. Discontinue use and consult a doctor if you experience stomach pain, cramps, severe headache, fever, or rash. Avoid the tablet if you have experienced blood abnormalities or kidney issues with medications like Sulphasalazine.
Disease interactions
Before taking Mesacol CR 500mg Tablet, it is essential to inform your doctor if you have a stomach ulcer, asthma, lung problems, or any medical condition that can lead to bleeding, liver issues, kidney problems, or blood disorders. This information is crucial as these existing health conditions may interact with the medication and affect its effectiveness or lead to potential complications. Ensuring that your healthcare provider is aware of your medical history will help them make informed decisions regarding the usage of Mesacol CR 500mg Tablet and adjust the dosage or recommend alternate treatment options if necessary. It is always best to disclose all relevant health information to your doctor before starting any new medication to promote safe and effective treatment outcomes.
What if you forgot to take Mesacol CR 500mg Tablet?
If you forget to take your Mesacol CR 500mg Tablet at the scheduled time, take it as soon as you remember. But if it's close to the time for your next dose, just skip the missed one and continue with your regular dosing schedule. It's important not to take a double dose to make up for the missed one. This helps maintain consistency in your medication routine and ensures you are following the prescribed regimen effectively.
What happens if you take overdose of Mesacol CR 500mg Tablet?
If you or someone takes an excessive amount of Mesacol CR 500mg Tablet by accident, it is crucial to seek urgent medical attention. Notify your doctor immediately. Overdosing on this medication can lead to various symptoms such as ringing in the ears (tinnitus), dizziness, headaches, confusion, drowsiness, shortness of breath, excessive loss of fluids (resulting from sweating, diarrhea, or vomiting), light-headedness (caused by low blood sugar levels), rapid breathing, and possibly fever. Prompt action is essential in case of a suspected overdose of Mesacol CR 500mg Tablet.
Related lab tests
Related Lab Tests for monitoring patients taking Mesacol CR 500mg Tablet may include:
1. Anti Neutrophilic Cytoplasmic Antibody (ANCA) - This test helps in evaluating autoimmune diseases, including inflammatory bowel diseases.
2. Anti Saccharomyces Cerevisiae Antibodies (ASCA), IgA, and IgG - These tests may be useful in diagnosing and managing inflammatory bowel diseases, like Crohn's disease.
3. C-Reactive Protein Quantitative - This test measures the level of inflammation in the body, which can be helpful in monitoring the response to treatment with Mesacol CR 500mg Tablet.
4. Erythrocyte Sedimentation Rate (ESR) - ESR is a non-specific test that indicates inflammation in the body and can aid in monitoring the disease activity in patients with inflammatory bowel diseases.
In addition to these lab tests, healthcare providers may also recommend colonoscopy and sigmoidoscopy procedures to assess the health of the colon and detect any abnormalities. These tests are valuable for monitoring the disease progression and effectiveness of treatment in patients using Mesacol CR 500mg Tablet.
Additional Information
Habit Forming | No |
Chemical Class | Aminosalicylic Acids Derivative |
Therapeutic Class | - |
Action Class | 5- Aminosalicylic acid (5-ASA) |
FAQs
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The information provided on this website is to the best of our abilities to ensure it is accurate, reliable, and reviewed by a team of professionals. It should not be used to diagnose, prevent, or cure any health problem. The information presented here is not intended to create a doctor-patient relationship or replace a registered medical practitioner's advice, diagnosis, or treatment. The absence or provision of any information or warning regarding any medicine should not be assumed as an implied or explicit assurance of safety or efficacy. We highly recommend consulting your registered medical practitioner for all queries or doubts related to your medical condition. Do not ignore professional medical advice or delay seeking it based on the content encountered on our website. We intend to support, not replace, the doctor-patient relationship.
₹230
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Content verified by

Dr. Archana Prabhakar
MBBS, M.Med (Family Medicine)
Last update on 01-Oct-2024