Lupride Injection

By Lupride

Rx

0ml Injection in a Vial

Composition icon

Composition

Leuprolide(1mg/0.5ml)

Manufacturer - Sun Pharmaceutical Industries Ltd icon

Manufacturer - Sun Pharmaceutical Industries Ltd

Plot no 107/108,Namli block , Ranipool, East Sikkim 737135

Expires on or after icon

Expires on or after

April, 2026

About Lupride Injection

Lupride Injection is a medication widely used in treating various conditions. It is primarily used in the treatment of prostate cancer, endometriosis, uterine fibroids, and central precocious puberty. Prostate cancer is found only in men and affects the prostate gland, which produces fluids that support sperm. Endometriosis, on the other hand, occurs when tissue similar to the uterine lining grows outside the uterus. Uterine fibroids and central precocious puberty are also conditions treated by Lupride Injection.

The active ingredient in Lupride Injection is Leuprolide, which belongs to the class of gonadotropin-releasing hormone (GnRH) agonists. It acts similarly to the naturally occurring GnRH produced by the hypothalamus gland in the brain. By inhibiting the synthesis of testosterone in men and estrogen in women, Lupride Injection helps to reduce hormone levels, which can slow down the growth of cancer cells in prostate cancer and shrink endometriosis and breast cancer tissues.

It is crucial to follow your doctor's instructions when taking Lupride Injection. The dosage will be determined based on your condition, and it is essential to take it as prescribed. Common side effects of Lupride Injection may include decreased libido, increased sweating, fatigue, muscle weakness, hot flashes, and potential impacts on bone health. To mitigate the risks of bone density reduction, it is recommended to take vitamin D and calcium supplements while on this medication. Menstrual periods may also stop for a few weeks during treatment, and any abnormal bleeding should be promptly reported to your doctor.

Before starting Lupride Injection, inform your healthcare provider about any medical history, including alcohol consumption, smoking habits, or osteoporosis. It is important to disclose all medications you are currently taking to avoid interactions. Lupride Injection should not be used during pregnancy or breastfeeding, and effective contraception is advised for both men and women to prevent pregnancy during treatment.Additionally, it is not recommended for children below two years of age.

Lupride 3.75mg Injection (Depot) is another variant of Leuprolide, used to manage conditions like endometriosis and preoperative hematologic improvement in women with fibroids-induced anemia. Endometriosis is a chronic disease characterized by tissue similar to the uterine lining growing outside the uterus, leading to symptoms like pain, infertility, and other discomforts. This injection should be avoided by individuals allergic to Leuprolide or similar compounds and used with caution in patients with liver or kidney impairments or abnormal uterine bleeding.

Common side effects of Lupride 3.75mg Injection (Depot) may include hot flashes, sweating, headaches, gastrointestinal issues, reduced libido, and dizziness. It is important to consult your doctor if any of these side effects worsen. Pregnant women, premenarcheal children, and postmenopausal women should not use Lupride 3.75mg Injection (Depot) without medical advice.

Always consult your healthcare provider before starting or stopping any medication, and follow their guidance for the safest and most effective treatment plan tailored to your specific condition.


Benefits

Lupride Injection offers various benefits in treating different medical conditions. In men with prostate cancer, this injection helps by decreasing or stopping the growth of cancer cells. By reducing the levels of testosterone, a natural hormone in males, Lupride Injection aids in alleviating difficulty with urination, ultimately making it easier for patients to urinate.

For women with endometriosis, Lupride Injection is effective in managing symptoms such as lower stomach or back pain, menstrual pain, pain during and after intercourse, constipation, diarrhea, and nausea. By inhibiting the rapid growth of the uterine lining and endometriosis tissue, this medication provides relief from these distressing symptoms. It is crucial to take Lupride Injection regularly for optimal effectiveness, and additional medications or procedures may be necessary to control endometriosis effectively.

Furthermore, Lupride Injection is beneficial in treating uterine fibroids by controlling symptoms like heavy menstrual bleeding and lower back pain. The injection works by reducing the size of existing fibroids and preventing further growth. By blocking the enzyme responsible for fibroid growth, Lupride Injection helps shrink the fibroids and alleviate associated symptoms.

In cases of precocious puberty, where puberty begins prematurely in children, Lupride Injection plays a vital role in delaying the onset of adulthood. This injection helps limit precocious puberty by slowing down the process of physical development in children before the appropriate age. It is essential to note that Lupride Injection for precocious puberty should only be administered under a doctor's supervision to ensure the best outcome.

Overall, Lupride Injection containing Leuprolide, a gonadotropin-releasing hormone (GnRH) agonist, is a valuable medication for managing prostate cancer, endometriosis, uterine fibroids, and precocious puberty. Its synthetic hormone properties mimic the natural GnRH hormone, providing effective treatment by targeting hormone levels specific to each condition.


How to use the Lupride Injection

When using Lupride Injection, it's essential to remember that only a qualified healthcare professional should administer it – do not attempt to self-administer. The injection will typically be given intramuscularly, meaning it will be injected into a muscle in your body. This medication comes in different strengths, such as Lupride Injection 0.5 ml or LUPRIDE 3.75MG INJECTION. Your doctor will determine the appropriate dose and duration of treatment based on factors like your age, body weight, and the specific condition being treated. Trust your healthcare provider to administer Lupride Injection safely and effectively to ensure you receive the best possible care for your needs.


Uses of Lupride Injection

Lupride Injection is commonly used for various medical conditions, including the treatment of prostate cancer, endometriosis, uterine fibroids, and precocious puberty. In prostate cancer patients, it plays a significant role in managing the condition. For individuals with endometriosis, Lupride Injection is often utilized to alleviate pain and reduce endometriotic lesions. Women suffering from uterine fibroids and anemia may benefit from this injection as a preoperative intervention to improve their blood count, particularly when hormonal suppression is deemed essential for a three-month period. Furthermore, Lupride Injection is also employed in the treatment of precocious puberty, helping to address this condition effectively.


What conditions Lupride Injection treats?

Lupride Injection is used to treat conditions such as prostate cancer, breast cancer, endometriosis, and precocious puberty. Prostate cancer affects the prostate gland in men and may cause urinary issues and sexual problems. Breast cancer develops in breast cells and can spread to other parts of the body through lymph nodes. Endometriosis involves tissue growing outside the uterus, leading to pain and irregular periods. Precocious puberty causes early physical changes in children. Lupride Injection helps manage symptoms and slow down the progression of these conditions.


Should you consult a doctor?

If you experience undiagnosed abnormal uterine bleeding, it is important to seek medical attention before starting LUPRIDE 3.75MG INJECTION(DEPOT) treatment. Additionally, it is essential to inform your doctor if you have a strong family history of osteoporosis before receiving the injection. This information will help your healthcare provider assess whether LUPRIDE 3.75MG INJECTION(DEPOT) is suitable for you and make any necessary adjustments to your treatment plan.


Side effects of Lupride Injection

Lupride Injection may cause various side effects, although most of them are temporary and tend to fade as your body gets used to the medication. These side effects include decreased libido, testicular atrophy, increased sweating, fatigue, muscle weakness, erectile dysfunction, hot flashes, weight changes, hot flushes, bone pain, loss of interest in sexual intercourse, inability to have an erection, tiredness, difficulty sleeping, headaches, breast tenderness, changes in breast size, mood swings, abdominal pain, vomiting, acne, vaginal bleeding, spotting, and injection site reactions such as skin hardening, redness, pain, abscesses, swelling, nodules, ulcers, and skin damage.

Some other possible side effects of Lupride Injection are hot flashes, sweating, headaches, vaginitis (vaginal inflammation), depression or emotional lability, general pain, weight changes, nausea, vomiting, reduced libido, dizziness, acne, skin reactions, joint disorders, oedema (swelling due to water retention), paraesthesia (burning and pricking sensation), gastrointestinal disturbances, neuromuscular disorders, breast changes or breast pain, nervousness, extreme weakness, and urinary tract infections.

It is important to note that in rare cases, you may experience severe side effects that require immediate medical attention. These include signs of pituitary apoplexy like a sudden headache, visual changes, vomiting, weakened eye muscles, altered mental status, or sudden loss of heart function, urinary tract infections, renal calculus (kidney stones), and depression. If you encounter any of these severe side effects, it is crucial to stop using Lupride Injection and contact your doctor right away for appropriate guidance and treatment.


Safety advice

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liver

Limited information is currently available regarding the use of Lupride Injection in individuals with liver disease. It is crucial to seek guidance from your healthcare provider before using this medication in such cases. Consulting with your doctor is necessary to ensure the safe and appropriate use of Lupride Injection in relation to liver health.

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kidney

Limited data exists on Lupride Injection use in kidney disease patients. Advised to consult doctor for guidance.

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alcohol

When using Lupride Injection, caution is advised when consuming alcohol. It is recommended to consult your doctor regarding alcohol consumption.

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driving

While using Lupride Injection, avoid driving or using machinery if you feel drowsy, dizzy, or have visual disturbances, as these side effects may impair your ability to drive safely.

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pregnancy

It is not safe to use Lupride Injection during pregnancy as it can harm the developing baby. Consult your doctor for advice due to harmful effects seen in studies on pregnant women and animals.

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breastfeeding

It is better to consult your doctor before using Lupride Injection during breastfeeding as there is no specific information available regarding its safety in this situation.


Age above 75(Geriatrics)

LUPRIDE 3.75MG INJECTION(DEPOT) is not recommended for use in postmenopausal women. Consult your doctor before receiving.

Age below 6 months(Pediatrics)

LUPRIDE 3.75MG INJECTION(DEPOT) is not recommended for use in premenarcheal children and adolescents (below 18 years). Consult your doctor before receiving.

Consumption warning before consuming Lupride Injection

Before using Lupride Injection 0.5 ml, it is important to note several warnings for your safety. If you have allergies to Lupride Injection 0.5 ml or any other medications, inform your doctor. This injection can harm an unborn baby if used during pregnancy, so it is not recommended for pregnant or breastfeeding women. To avoid pregnancy during treatment, use effective contraception. Men should also be cautious about fertility issues when considering starting a family while using this injection. Exercise care when using Lupride Injection 0.5 ml in elderly patients and children above two years old. It's common for symptoms to worsen temporarily when starting the treatment; notify your doctor if this persists beyond 2 months. Seek immediate medical attention if you experience seizures or unusual mood or behavior changes. Before starting treatment, disclose any medical history of liver or kidney conditions, heart issues, depression, or other health concerns. Additionally, Lupride Injection 0.5 ml may impact heart rhythm and lead to dizziness, affecting the ability to drive or operate machinery. Be cautious if you have heart problems.


What if you forgot to take Lupride Injection?

If you happen to miss a dose of your Lupride Injection, it is important to consult your doctor promptly. It is advisable to seek guidance from your healthcare provider in such situations to determine the appropriate course of action. Remember to adhere to your prescribed treatment schedule to ensure the effectiveness of your medication regimen. Consulting with your doctor will help you address any concerns related to missed doses and ensure that you are on track with your treatment plan.


What happens if you take overdose of Lupride Injection?

Overdose is unlikely with LUPRIDE 3.75MG INJECTION (DEPOT) since it is administered by healthcare professionals in a hospital setting. However, if by any chance you or someone else is given too much of this medicine, seek immediate medical help by contacting your doctor or going to the nearest hospital. It is important to address any concerns about potential overdose promptly to ensure proper care and management.


Related lab tests

When you are taking Lupride Injection, there are certain lab tests that your healthcare provider may recommend. These tests help in monitoring your health and the effects of the medication. Two important lab tests to keep in mind are the Prostate Specific Antigen (Free) PSA and Prostate Specific Antigen (Total) PSA tests. These tests measure a protein produced by the prostate gland. Monitoring PSA levels is crucial in patients using Lupride Injection, especially those with prostate conditions, as it helps in assessing the prostate health and detecting any abnormalities. Regularly getting these tests done can provide valuable information to your healthcare team about how your body is responding to the medication. It is important to follow your healthcare provider's advice on when to get these tests done to ensure proper monitoring of your health.


Additional Information

Habit FormingNo
Chemical ClassGNRH Analogue
Therapeutic ClassGYNAECOLOGICAL
Action Class-

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The information provided on this website is to the best of our abilities to ensure it is accurate, reliable, and reviewed by a team of professionals. It should not be used to diagnose, prevent, or cure any health problem. The information presented here is not intended to create a doctor-patient relationship or replace a registered medical practitioner's advice, diagnosis, or treatment. The absence or provision of any information or warning regarding any medicine should not be assumed as an implied or explicit assurance of safety or efficacy. We highly recommend consulting your registered medical practitioner for all queries or doubts related to your medical condition. Do not ignore professional medical advice or delay seeking it based on the content encountered on our website. We intend to support, not replace, the doctor-patient relationship.

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Dr. Archana Prabhakar

MBBS, M.Med (Family Medicine)

Last update on 11-Feb-2025