Lupride Depot 45mg Injection
By Lupride
Rx
1 Injection in a Vial

Composition
Leuprolide(45mg)

Manufacturer - Sun Pharmaceutical Industries Ltd
Plot no 107/108,Namli block , Ranipool, East Sikkim 737135

Expires on or after
July, 2025
About Lupride Depot 45mg Injection
Lupride Depot 45mg Injection is a medication used in the treatment of various conditions such as prostate cancer, endometriosis, uterine fibroids, and central precocious puberty (early puberty). It is administered as an injection beneath the skin by a qualified medical professional. The dosage and frequency of administration will be determined by your doctor based on your specific condition, and it is crucial to follow their instructions precisely to avoid serious side effects.
This medication may take some time to show its full effects, so it is important to continue taking it as prescribed by your doctor. Common side effects of Lupride Depot 45mg Injection include decreased libido, increased sweating, fatigue, muscle weakness, and hot flashes. Prolonged use of this medication may lead to weakened bones and a reduction in bone mineral density, for which your doctor may recommend taking vitamin D and calcium supplements.
It is important to inform your doctor of any history of alcohol consumption, smoking, or osteoporosis before starting this medication, as well as disclose all other medications you may be taking. Lupride Depot 45mg Injection is not recommended during pregnancy or breastfeeding, and both males and females should use effective contraception during treatment to prevent pregnancy.
LUPRIDE 3.75MG INJECTION(DEPOT) contains Leuprolide and is classified as a Gonadotropin Releasing Hormone (GnRH) agonist. This drug is used to manage conditions like endometriosis and uterine fibroids, helping to alleviate pain and reduce lesions. Endometriosis is a chronic condition where tissue similar to the uterus lining grows outside the uterus, causing symptoms like pelvic pain, infertility, and painful menstruation.
Before receiving LUPRIDE 3.75MG INJECTION(DEPOT), ensure you are not allergic to Leuprolide or related compounds. Inform your doctor of any liver or kidney impairment, abnormal uterine bleeding, chronic alcohol or tobacco use, or family history of osteoporosis. This medication is not recommended for use in pregnant or breastfeeding women, premenarcheal children, or postmenopausal women, unless deemed necessary by a healthcare provider.
Some common side effects of LUPRIDE 3.75MG INJECTION(DEPOT) include hot flashes, general pain, headaches, gastrointestinal disturbances, water retention-related swelling, nausea, vomiting, reduced libido, and dizziness. Contact your doctor if any of these side effects become severe.
Benefits
Lupride Depot 45mg Injection offers a range of benefits in different medical conditions. In the treatment of prostate cancer, this injection targets cancer cells by reducing testosterone levels in men, ultimately slowing down or halting the growth of these malignant cells. By doing so, Lupride Depot 45mg Injection can alleviate symptoms such as urinary difficulties, making it easier for patients to urinate comfortably.
For individuals suffering from endometriosis, a condition characterized by the abnormal growth of womb-like tissue outside the uterus, Lupride Depot 45mg Injection plays a vital role in managing the symptoms associated with this condition. By regulating the growth of endometriosis tissue and uterine lining, this medication helps alleviate common symptoms like lower stomach or back pain, menstrual pain, and discomfort during intercourse. It can also aid in enhancing fertility by addressing the root cause of endometriosis.
Moreover, Lupride Depot 45mg Injection is effective in treating uterine fibroids, non-cancerous growths in the uterus that often lead to symptoms such as heavy menstrual bleeding and lower back pain. By inhibiting the action of the enzyme responsible for fibroid growth, this injection not only reduces the existing fibroid size but also prevents further growth, thus providing relief from associated symptoms.
In cases of precocious puberty, where a child's body starts transitioning to adult form prematurely, Lupride Depot 45mg Injection proves beneficial in delaying the onset of puberty symptoms and limiting the progression of early adulthood. It is crucial to note that this medication should only be administered under medical supervision to ensure optimal results and safety.
Overall, Lupride Depot 45mg Injection emerges as a valuable treatment option across various conditions, offering relief from symptoms and improving the quality of life for individuals struggling with prostate cancer, endometriosis, uterine fibroids, and precocious puberty.
How to use the Lupride Depot 45mg Injection
To use Lupride Depot 45mg Injection, it is crucial to remember that only a doctor or a nurse should give you this medication. Please do not try to administer it yourself. This injection is typically given intramuscularly, meaning it is injected into the muscle by a healthcare professional. Your doctor will determine the appropriate dosage and treatment duration based on factors such as your age, body weight, and specific medical condition. Trust your healthcare provider to administer Lupride Depot 45mg Injection safely and effectively for your treatment.
Uses of Lupride Depot 45mg Injection
Lupride Depot 45mg Injection is utilized in the treatment of various conditions. It is commonly used for managing prostate cancer, endometriosis, uterine fibroids, and precocious puberty (premature puberty). In the case of endometriosis, this injection works by relieving pain and reducing the growth of endometriotic lesions. Additionally, it is employed to improve the blood count before surgery in women with fibroid-induced anemia who require hormonal suppression for three months. This injection serves as a beneficial option in addressing these medical issues effectively.
What conditions Lupride Depot 45mg Injection treats?
Lupride Depot 45mg Injection is used to treat various conditions, including prostate cancer, endometriosis, uterine fibroids, and central precocious puberty. In prostate cancer, it reduces testosterone levels to halt cancer cell growth and ease urination. For endometriosis, it slows abnormal tissue growth, relieving symptoms like pain and infertility. It controls symptoms of uterine fibroids and delays premature puberty onset in children. Side effects may include decreased libido, hot flashes, and muscle weakness. It's crucial to follow your doctor's instructions and inform them of any existing conditions or medications.
Should you consult a doctor?
You should seek a doctor before using Lupride Depot 45mg Injection if you have undiagnosed abnormal uterine bleeding. It is also important to inform your doctor if you have a strong family history of osteoporosis before receiving this injection. If you experience any unusual symptoms or side effects after taking Lupride Depot 45mg Injection, consult your doctor immediately. Symptoms such as severe abdominal pain, persistent headaches, or any other concerning issues should prompt you to seek medical advice promptly. It is crucial to be proactive about your health and seek medical help when needed to ensure your well-being.
Side effects of Lupride Depot 45mg Injection
When using Lupride Depot 45mg Injection, you may experience some side effects that typically subside as your body gets used to the medication. These include decreased libido, testicular atrophy, increased sweating, fatigue, muscle weakness, erectile dysfunction, and hot flashes. Additionally, you might encounter headaches, vaginal inflammation, feelings of depression or emotional lability, general pain, changes in weight, nausea, vomiting, reduced libido, dizziness, acne, skin reactions, joint issues, swelling due to water retention, burning or pricking sensations, gastrointestinal problems, neuromuscular disorders, breast changes or pain, nervousness, extreme weakness, and urinary tract infections.
It's important to be aware of more serious side effects that require immediate medical attention. If you experience signs of pituitary apoplexy like sudden headaches, visual changes, vomiting, weakened eye muscles, altered mental state, or sudden heart function loss, stop using the injection and contact your doctor promptly. Other severe side effects may include renal calculi (kidney stones) and depression. Remember, it's crucial to consult your healthcare provider if any side effects persist or if you have concerns about them.
Safety advice

liver
Consult your healthcare provider for guidance on the safe use of Lupride Depot 45mg Injection if you have liver disease. Limited data is accessible concerning its utilization in individuals with liver conditions. It is advisable to discuss any liver-related concerns with your doctor.

kidney
Limited information exists regarding the use of Lupride Depot 45mg Injection in individuals with kidney disease. Please seek guidance from your doctor.

alcohol
When using Lupride Depot 45mg Injection, caution is advised when consuming alcohol. It is recommended to consult your doctor before consuming alcohol while on this medication.

driving
While using Lupride Depot 45mg Injection, if you feel drowsy, dizzy, or have visual disturbances, avoid driving or using machinery. These side effects could impact your ability to drive safely.

pregnancy
During pregnancy, it is not safe to use Lupride Depot 45mg Injection as it can harm the developing baby. Consult your doctor for advice as studies have shown harmful effects in pregnant women and animals.

breastfeeding
It is better to consult your doctor before using Lupride Depot 45mg Injection during breastfeeding.
Age above 75(Geriatrics)
Age below 6 months(Pediatrics)
Consumption warning before consuming Lupride Depot 45mg Injection
Before consuming Lupride Depot 45mg Injection, it's important to take note of some crucial warnings. This medication is commonly used to treat conditions like prostate cancer, endometriosis, uterine fibroids, and central precocious puberty. It is administered via injection under the skin by a qualified medical professional, following specific dosage instructions provided by your doctor. Taking Lupride Depot incorrectly or in excess can lead to severe side effects.
Common side effects of this medication include decreased libido, increased sweating, fatigue, muscle weakness, and hot flashes. Prolonged use may also result in weakened bones and reduced bone mineral density, hence the recommendation to take vitamin D and calcium supplements while on this treatment. It's important to inform your doctor if menstrual bleeding persists during the course of treatment, as this medication may cause menstrual periods to cease for 7-12 weeks.
Prior to starting Lupride Depot, disclose to your doctor any history of alcohol consumption, smoking, or osteoporosis. Also, inform your healthcare provider about all medications you are currently taking, as interactions can occur. It is crucial to avoid using this medication during pregnancy or while breastfeeding. Effective contraception by both males and females is advised throughout the treatment to prevent pregnancy.
What if you forgot to take Lupride Depot 45mg Injection?
If you forget to take a dose of Lupride Depot 45mg Injection, it is important to consult your doctor promptly. It is crucial to seek guidance from your healthcare provider for advice on how to proceed after missing a dose of this medication. It is always recommended to follow the instructions given by your doctor to ensure the effectiveness of your treatment.
What happens if you take overdose of Lupride Depot 45mg Injection?
Overdose with Lupride Depot 45mg Injection is unlikely to occur because it is administered only by a doctor or nurse in a hospital. If by chance you or someone else gets too much of this medication, it's crucial to seek medical help right away. Immediate consultation with your doctor or a visit to the nearest hospital is essential in case of an accidental overdose. This ensures prompt medical attention and appropriate management to address any potential concerns.
Related lab tests
Related Lab Tests for Lupride Depot 45mg Injection include Prostate Specific Antigen (Free) and Prostate Specific Antigen (Total). These tests are commonly used to monitor and evaluate prostate health. Prostate Specific Antigen (PSA) is a protein produced by the prostate gland, and elevated levels may indicate prostate issues such as inflammation, infection, enlargement, or even cancer. The Free PSA test measures the amount of unbound PSA in the blood, while the Total PSA test measures the total amount of PSA present, both bound and unbound. These tests are essential in assessing prostate conditions before and during treatment with Lupride Depot 45mg Injection.
Additional Information
Habit Forming | No |
Chemical Class | GNRH Analogue |
Therapeutic Class | GYNAECOLOGICAL |
Action Class | - |
FAQs
Disclaimer
The information provided on this website is to the best of our abilities to ensure it is accurate, reliable, and reviewed by a team of professionals. It should not be used to diagnose, prevent, or cure any health problem. The information presented here is not intended to create a doctor-patient relationship or replace a registered medical practitioner's advice, diagnosis, or treatment. The absence or provision of any information or warning regarding any medicine should not be assumed as an implied or explicit assurance of safety or efficacy. We highly recommend consulting your registered medical practitioner for all queries or doubts related to your medical condition. Do not ignore professional medical advice or delay seeking it based on the content encountered on our website. We intend to support, not replace, the doctor-patient relationship.
₹33250
Inclusive of all taxes
Content verified by

Dr. Archana Prabhakar
MBBS, M.Med (Family Medicine)
Last update on 01-Oct-2024