Lupinib 400 Tablet

By Lupinib

Rx

10 Tablet in a Strip

Composition icon

Composition

Imatinib mesylate(400mg)

Manufacturer - Lupin Ltd icon

Manufacturer - Lupin Ltd

Lupin Ltd, 3rd floor Kalpataru Inspire, Off. W E Highway, Santacruz (East), Mumbai 400 055. India

Expires on or after icon

Expires on or after

April, 2026

About Lupinib 400 Tablet

Lupinib 400 Tablet is a medication belonging to the class of anti-cancer drugs, specifically designed to treat various types of cancer. Primarily used for blood cancers such as chronic myeloid leukemia and acute lymphocytic leukemia, as well as gastrointestinal stromal tumors. Cancer occurs due to genetic changes where cells uncontrollably divide and spread to nearby tissues. With over 100 types of cancer including lung cancer, blood cancer, and breast cancer, the Lupinib 400 Tablet contains Imatinib, a key component that targets specific proteins responsible for the growth and spread of cancer cells.

Imatinib in Lupinib 400 Tablet works by inhibiting enzymes that promote cancer cell proliferation, ultimately leading to cell death (apoptosis) which slows down or halts the growth and spread of cancer cells in the body. It is crucial to adhere to the prescribed dosage and continue taking the medication as advised by your doctor. Possible side effects may include nausea, vomiting, edema, fatigue, muscle cramps, musculoskeletal pain, diarrhea, rash, and abdominal pain, most of which tend to resolve over time. If you experience persistent side effects, it is recommended to consult your healthcare provider.

Regular monitoring of liver function and blood cell count is necessary while on Lupinib 400 Tablet treatment. Additionally, caution is advised if there is a history of kidney, liver, or heart problems, hepatitis B infection, or thrombotic microangiopathy. Due to the potential sensitivity to sunlight, it is important to protect your skin with a high SPF sunscreen. If unexpected rapid weight gain occurs or if there is a history of hepatitis B infection, informing your doctor is crucial. The medication is generally not recommended for pregnant or breastfeeding women and should be used with care in children, adolescents, and elderly patients.

Furthermore, besides blood cancers, Lupinib 400 Tablet is also effective in treating myelodysplastic/myeloproliferative diseases, eosinophilic syndromes, gastrointestinal stromal tumors, and dermatofibrosarcoma protuberans. It is essential to disclose any relevant medical history or existing conditions to your healthcare provider before starting the treatment. If you experience side effects like nausea, vomiting, diarrhea, headache, weight changes, loss of appetite, altered taste perception, blurred vision, or weakness, it is advisable to seek medical advice promptly.


Benefits

Lupinib 400 Tablet offers significant benefits in the treatment of various types of cancer. It is specifically designed to target the proteins responsible for the growth and spread of cancer cells in conditions such as blood cancers, gastrointestinal stromal tumors, skin cancer (dermatofibrosarcoma protuberans), and aggressive systemic mastocytosis in the bone marrow. By inhibiting these proteins, the medication effectively slows down or halts the growth of cancer, leading to the shrinkage of tumors and a reduction in their progression. Ultimately, patients may experience improvements in their overall well-being as a result of the medication's ability to impede the advancement of the disease.


How to use the Lupinib 400 Tablet

To use Lupinib 400 Tablet, it is important to follow the directions given by your doctor. Take the medicine in the prescribed dose and for the duration recommended by your doctor. It is essential to swallow the tablet whole, without chewing, crushing, or breaking it. It is advised to take Lupinib 400 Tablet with food to ensure optimal absorption and effectiveness. Following the instructions precisely will help you get the most benefit from this medication.


Uses of Lupinib 400 Tablet

The primary use of Lupinib 400 Tablet is in the treatment of cancer. This medication is specifically prescribed to help in managing cancer and its related symptoms. Lupinib 400 Tablet is effective in targeting and controlling cancer cells, aiding in slowing down the progression of the disease. It is an important part of cancer therapy, often used in combination with other treatments to improve outcomes for patients undergoing cancer treatment.


What conditions Lupinib 400 Tablet treats?

Lupinib 400 Tablet is used in the treatment of various cancers including blood cancers, gastrointestinal stromal tumors, dermatofibrosarcoma protuberans (a skin tumor), and aggressive systemic mastocytosis (a bone marrow condition). It works by targeting specific proteins that promote the growth and spread of cancer cells. This action helps to slow down or stop the growth of cancer, shrink tumors, and improve the patient's well-being. It is important to take the medication with food at the same time daily, continuing as directed by the doctor to achieve optimal benefits.


Should you consult a doctor?

Seek medical attention immediately if you experience unexpected rapid weight gain, severe edema (swelling), difficulty breathing, persistent cough, unusual bleeding, or signs of hemorrhage while taking Lupinib 400 Tablet. Additionally, contact your doctor if you develop severe or persistent nausea, vomiting, muscle cramps, musculoskeletal pain, diarrhea, rash, fatigue, abdominal pain, dry eyes, dizziness, or blurred vision. If any of these side effects persist or cause concern, consult your healthcare provider promptly. It is crucial to keep your doctor informed about all medications you are taking and any changes in your health status. Remember, do not drive or engage in activities that require mental focus if you experience dizziness. Also, if you have concerns or questions, always seek guidance from your healthcare team.


Side effects of Lupinib 400 Tablet

When taking Lupinib 400 Tablet, some individuals may experience certain side effects. These side effects are generally mild and often go away as the body gets used to the medication. However, it is essential to consult your doctor if the side effects persist or if you have concerns about them. Possible side effects of Lupinib 400 Tablet include swelling (edema), nausea, vomiting, muscle cramps, musculoskeletal pain (affecting bones, muscles, or joints), diarrhea, rash, fatigue, abdominal pain, bleeding, breathing problems, cough, weight gain, dry eyes, dizziness, and hemorrhage. Be vigilant to these effects and seek medical advice if needed.


Safety advice

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liver

Lupinib 400 Tablet should be used cautiously by individuals with severe liver disease. It may be necessary to adjust the dosage of Lupinib 400 Tablet in these cases to ensure safe use. It is important to consult with your doctor regarding the appropriate use of this medication if you have a liver condition.

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kidney

Lupinib 400 Tablet requires caution in patients with kidney disease. Adjustments to the dosage may be necessary. Consult your doctor for personalized guidance.

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alcohol

When taking Lupinib 400 Tablet, it is advised to consult your doctor before consuming alcohol. The safety of combining alcohol with this medication is uncertain.

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driving

When taking Lupinib 400 Tablet, be cautious while driving due to potential side effects impacting driving ability.

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pregnancy

Lupinib 400 Tablet should not be used during pregnancy due to the risk it poses to the developing baby. In rare life-threatening situations, a doctor might prescribe it, weighing the benefits against the risks. Consult your doctor before use.

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breastfeeding

Lupinib 400 Tablet is not safe to use while breastfeeding. Limited data indicates it can pass into breastmilk, potentially harming the baby. Avoid breastfeeding while taking this medication and for 15 days after stopping it.


Consumption warning before consuming Lupinib 400 Tablet

Before consuming Lupinib 400 Tablet, it is important to be aware of certain precautions. This medication is primarily used to treat various types of cancers such as chronic myeloid leukemia, acute lymphocytic leukemia, and gastrointestinal stromal tumors. Additionally, it is prescribed for skin tumor dermatofibrosarcoma protuberans and aggressive systemic mastocytosis. Lupinib 400 Tablet should be taken with food daily at the same time for maximum effectiveness. Follow your doctor's instructions regarding the duration of treatment.


Misuse or overdose of this medication can lead to severe side effects, so it is crucial to take it as prescribed. Common side effects may include edema, nausea, vomiting, muscle cramps, diarrhea, fatigue, and abdominal pain. If you notice rapid weight gain or experience dizziness, inform your doctor immediately.


Regular monitoring of blood cells and liver function may be necessary while using this medication. Avoid driving or activities requiring mental alertness if you experience dizziness or blurry vision. Inform your healthcare provider about all other medications you are taking as interactions can occur. Lupinib 400 Tablet is not recommended during pregnancy or breastfeeding, and both males and females should use effective contraception to prevent pregnancy during treatment.


What if you forgot to take Lupinib 400 Tablet?

If you forget to take a dose of Lupinib 400 Tablet, just skip it and take the next dose as per your regular schedule. It's important not to take a double dose to make up for the missed one. Simply resume your normal dosing routine to maintain the effectiveness of the medication.


Additional Information

Habit FormingNo
Chemical ClassBenzanilides Derivative
Therapeutic Class-
Action ClassTyrosine kinase inhibitors

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The information provided on this website is to the best of our abilities to ensure it is accurate, reliable, and reviewed by a team of professionals. It should not be used to diagnose, prevent, or cure any health problem. The information presented here is not intended to create a doctor-patient relationship or replace a registered medical practitioner's advice, diagnosis, or treatment. The absence or provision of any information or warning regarding any medicine should not be assumed as an implied or explicit assurance of safety or efficacy. We highly recommend consulting your registered medical practitioner for all queries or doubts related to your medical condition. Do not ignore professional medical advice or delay seeking it based on the content encountered on our website. We intend to support, not replace, the doctor-patient relationship.

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Dr. Archana Prabhakar

MBBS, M.Med (Family Medicine)

Last update on 01-Oct-2024