Lorbriqua 25mg Tablet

By Lorbriqua

Rx

30 Tablet in a Boxes

Composition icon

Composition

Lorlatinib(25mg)

Manufacturer - Pfizer Ltd icon

Manufacturer - Pfizer Ltd

The Capital, 1802, 18th Floor , Plot No. C-70, 'G' Block , Bandra Kurla Complex, Bandra East , Mumbai – 400051.

Expires on or after icon

Expires on or after

July, 2025

About Lorbriqua 25mg Tablet

Lorbriqua 25mg Tablet is a medication that falls under the category of drugs known to inhibit an enzyme called anaplastic lymphoma kinase (ALK). It is commonly prescribed to adults who are dealing with advanced stages of non-small cell lung cancer (NSCLC), which is a form of lung cancer where malignant cells develop in the lung tissues. This type of cancer can be influenced by various factors, with smoking being a major risk factor.

The active ingredient in Lorbriqua 25mg Tablet is Lorlatinib, which acts by targeting a specific enzyme known as tyrosine kinase. By doing so, it triggers the death of cancer cells in individuals who have genetic alterations related to the ALK gene. This medication is specifically meant for patients whose condition is linked to changes in the ALK tyrosine kinase gene.

Patients are advised to strictly follow their doctor's instructions or the information provided in the package leaflet when using this medicine to ensure they receive the maximum benefit. While taking Lorbriqua 25mg Tablet, individuals may encounter common side effects such as diarrhoea, constipation, joint pain, weight gain, headache, rash, and muscle pain. Although most of these side effects tend to resolve on their own over time, it is recommended to consult a healthcare professional if they persist.

Before starting treatment with Lorbriqua 25mg Tablet, pregnant or breastfeeding women should seek advice from their healthcare provider. Additionally, caution is advised while driving as this medication may cause tiredness and dizziness. It is important to avoid alcohol consumption while on Lorbriqua 25mg Tablet as it could exacerbate feelings of dizziness. This medication is not suitable for individuals under the age of 18, as its safety and effectiveness have not been established in this age group.

Lorbriqua 25mg Tablet falls under pregnancy category D, meaning it can potentially harm the fetus. Women of childbearing potential are advised to take precautions to avoid pregnancy while undergoing treatment with Lorbriqua 25mg Tablet. If breastfeeding, it is crucial to consult with a doctor to determine whether it is safe to continue taking this medication. Furthermore, individuals should keep their healthcare provider informed about their health status and any other medications they may be taking to mitigate the risk of adverse reactions. It's also important to discuss potential impacts on male fertility with a healthcare professional before starting treatment with Lorbriqua 25mg Tablet.


Benefits

Lorbriqua 25mg Tablet, containing Lorlatinib as its active ingredient, offers a range of benefits in the treatment of non-small cell lung cancer. This medication is particularly effective in shrinking tumor size and limiting the cancer from spreading to other parts of the body. Importantly, Lorbriqua 25mg Tablet is capable of crossing the blood-brain barrier, a vital network that shields the brain from harmful substances. This quality makes it a suitable option for treating cancer that has reached the brain.

Specifically designed for adults with advanced non-small cell lung cancer, Lorbriqua 25mg Tablet targets a specific genetic alteration in the ALK tyrosine kinase gene. By inhibiting the activity of tyrosine kinase enzymes, this medication aids in halting cancer cell growth and ultimately inducing their death in patients with ALK gene mutations.

By opting for Lorbriqua 25mg Tablet, patients can benefit from a treatment that not only addresses the existing cancer but also helps in preventing disease progression and reduces the risk of recurrence over an extended period. The unique mechanism of action of Lorlatinib makes it a valuable tool in the fight against non-small cell lung cancer, offering hope for improved outcomes and enhanced quality of life for individuals battling this disease.


How to use the Lorbriqua 25mg Tablet

To properly use Lorbriqua 25mg Tablet, follow your doctor's instructions on the dosage and duration. Swallow the tablet whole with water; do not crush, break, or chew it. You can take Lorbriqua 25mg Tablet with or without food, but it is recommended to take it at the same time each day for best results. Remember to not alter the tablet in any way before consumption. If you have any doubts or concerns about how to use this medication, consult your doctor or pharmacist for guidance.


Uses of Lorbriqua 25mg Tablet

Lorbriqua 25mg Tablet is used in the treatment of a type of lung cancer known as non-small cell lung cancer (NSCLC). It is specifically intended for the management of advanced stages of this condition. This medication is designed to be a part of the comprehensive treatment plan for individuals diagnosed with NSCLC.


What conditions Lorbriqua 25mg Tablet treats?

Lorbriqua 25mg Tablet is used to treat non-small cell lung cancer (NSCLC). NSCLC is a type of cancer where cancer cells develop in the lung tissues. It has different types, and smoking is a main risk factor for developing this condition.


Should you consult a doctor?

Seek medical attention if you experience worrisome or worsening side effects while taking Lorbriqua 25mg Tablet, such as swelling in arms, legs, hands, or feet, numbness or tingling in joints, arms, or legs, cognitive issues like confusion or forgetfulness, breathlessness, fatigue, weight gain, joint pain, mood changes, or diarrhea. Inform your doctor about any pre-existing medical conditions like kidney or heart disease, depression, seizures, heart rhythm issues, or breathing problems. Patients with high blood pressure, high cholesterol levels, or diabetes should also consult before starting this treatment. Due to potential interactions, disclose all current medications to your doctor. If side effects persist or if you have concerns, it's important to consult your healthcare provider promptly for appropriate guidance and potential dosage adjustments.


Side effects of Lorbriqua 25mg Tablet

When taking Lorbriqua 25mg Tablet, you may experience various side effects which typically do not warrant immediate medical attention and tend to lessen as your body adapts to the medication. However, if these side effects persist or cause concern, it is advisable to consult your healthcare provider. Some commonly reported side effects include fatigue, diarrhea, swelling (edema), high blood pressure, cough, joint pain, tingling or numbness in the feet and hands (peripheral neuropathy), weight gain, breathlessness, and mood changes. Additionally, there may be occurrences of hypercholesterolemia (high cholesterol), increased triglyceride levels in the blood, limb or skin swelling, double vision, pain, numbness, burning sensations or pins and needles, difficulty walking, elevated lipase and/or amylase enzyme levels, anemia, diarrhea, constipation, joint pain, weight gain, headache, rash, and muscle pain. It is essential to monitor these symptoms and seek professional advice if needed.


Safety advice

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liver

It is safe to use Lorbriqua 25mg Tablet in patients with liver disease. There is no need for any dose adjustment when using this tablet. However, it is important to note that the recommended dosage regimen has not been established for cases of moderate to severe hepatic impairment. Please consult with your doctor for proper guidance before using Lorbriqua 25mg Tablet.

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kidney

Lorbriqua 25mg Tablet requires caution in severe kidney disease. Consult your doctor for potential dose adjustments. No dose adjustments are needed for mild to moderate renal impairment.

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alcohol

Consult your doctor when consuming alcohol with Lorbriqua 25mg Tablet.

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driving

It is essential to be cautious when driving while taking Lorbriqua 25mg Tablet as the impact on driving ability is unknown. If you notice any symptoms that may impair your focus or reaction time, avoid driving.

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pregnancy

Lorbriqua 25mg Tablet may not be safe to use during pregnancy. Animal studies suggest potential harm to the developing baby, but limited human studies are available. Your doctor will evaluate the benefits and risks before prescribing. Please consult your doctor.

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breastfeeding

Lorbriqua 25mg Tablet must be used carefully when breastfeeding. It is recommended to pause breastfeeding until the mother's treatment is finished and the drug has cleared her system.


Consumption warning before consuming Lorbriqua 25mg Tablet

Before taking Lorbriqua 25mg Tablet 30's, it is essential to consult your doctor if you are pregnant or breastfeeding. This medication may cause tiredness and dizziness, so it's important to be cautious while driving. Avoid consuming alcohol while on Lorbriqua 25mg Tablet 30's as it can increase dizziness. Note that this medication is not recommended for children under 18 years old due to unknown safety and effectiveness. Lorbriqua 25mg Tablet 30's falls under pregnancy category D and can harm the fetus; women of childbearing age should avoid pregnancy during treatment. If breastfeeding, consult your doctor to determine if it is safe to take this medication. Keep your doctor informed about your health and medications to prevent any adverse effects. Additionally, Lorbriqua 25mg Tablet 30's may impact male fertility, so discuss fertility preservation with your doctor before starting this treatment.


Disease interactions

When considering the use of Lorbriqua 25mg Tablet, caution is advised for patients with liver disorders, kidney disorders, central nervous system (CNS) issues, and heart disorders. It is important to be cautious because these conditions may affect the way the medication works in the body. Patients with liver disorders might process the drug differently, while those with kidney disorders may have difficulty in excreting it. Central nervous system problems and heart disorders may also interact with the medication, potentially causing unwanted effects. Therefore, it is crucial to consult a healthcare provider before using Lorbriqua 25mg Tablet if you have any of these conditions to ensure safe and effective treatment.


Additional Information

Habit FormingNo
Chemical ClassPhenylpropanoid derivatives
Therapeutic Class-
Action ClassTyrosine kinase inhibitors

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Disclaimer

The information provided on this website is to the best of our abilities to ensure it is accurate, reliable, and reviewed by a team of professionals. It should not be used to diagnose, prevent, or cure any health problem. The information presented here is not intended to create a doctor-patient relationship or replace a registered medical practitioner's advice, diagnosis, or treatment. The absence or provision of any information or warning regarding any medicine should not be assumed as an implied or explicit assurance of safety or efficacy. We highly recommend consulting your registered medical practitioner for all queries or doubts related to your medical condition. Do not ignore professional medical advice or delay seeking it based on the content encountered on our website. We intend to support, not replace, the doctor-patient relationship.

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Dr. Archana Prabhakar

MBBS, M.Med (Family Medicine)

Last update on 11-Feb-2025