Leucovorin Injection

By Leucovorin

Rx

5ml Injection in a Vial

Composition icon

Composition

Calcium Leucovorin(50mg)

Manufacturer - Dabur India Ltd icon

Manufacturer - Dabur India Ltd

8/3, Asaf Ali Road, New Delhi-110002

Expires on or after icon

Expires on or after

July, 2025

About Leucovorin Injection

Leucovorin Injection is a medication used to counteract the harmful effects of methotrexate, which is an anticancer medicine. It is also utilized to treat cases of methotrexate overdose. The injection is administered slowly into the veins by a healthcare professional. Your doctor will determine the appropriate dosage and frequency of administration based on your specific condition, which may change over time. It is crucial to follow your doctor's instructions precisely, as incorrect usage or overconsumption can lead to severe side effects.

Common side effects of Leucovorin Injection include reactions at the injection site such as pain, swelling, and redness. If these side effects become bothersome or severe, it is important to inform your doctor. Measures may be taken to reduce or prevent these reactions. Regular blood tests are essential to monitor your blood cells and the concentration of methotrexate in your bloodstream.

Before taking Leucovorin Injection, it is important to discuss with your doctor if you have a history of seizures, liver or kidney issues, or if you are taking medications for infections. This medicine can interact with various other medications, particularly phenytoin used for seizures, so it is crucial to inform your healthcare team about all the medications you are currently taking. Additionally, if you are pregnant or breastfeeding, inform your doctor to ensure the safety of using this medication.


Benefits

Leucovorin Injection offers valuable benefits in preventing the harmful effects of methotrexate, a potent anti-cancer medication. By safeguarding the body cells against the detrimental impacts of methotrexate, this injection plays a crucial role in ensuring the optimal effectiveness of the anti-cancer treatment. Administered 24 hours after methotrexate, Leucovorin Injection acts as a form of vitamin B that helps in enhancing the anti-cancer effects of methotrexate. Additionally, it serves as a protective shield against potential side effects like anemia, thus promoting a more favorable overall treatment outcome. By incorporating Leucovorin Injection into cancer therapy regimens, patients can benefit from enhanced protection against the adverse effects of methotrexate, ultimately improving their quality of life during treatment.


How to use the Leucovorin Injection

When it comes to using Leucovorin Injection, it is important to always rely on the guidance of your doctor or nurse. This medication should never be taken by yourself. Your healthcare provider will administer the injection to you, so it is crucial to follow their instructions carefully. Avoid self-administration and trust the professionals for the safe and proper use of Leucovorin Injection. Remember, your well-being is the top priority, so always consult with your healthcare team for the best and safest practices when using this medication.


Uses of Leucovorin Injection

Leucovorin Injection is used to prevent the harmful effects of methotrexate, a medication commonly prescribed to treat various conditions such as cancer, psoriasis, and rheumatoid arthritis. When methotrexate is used to treat these conditions, it can sometimes lead to side effects that affect the body's normal function. The primary purpose of using Leucovorin Injection is to help mitigate or reduce these adverse effects caused by methotrexate therapy. By incorporating Leucovorin Injection into the treatment plan, healthcare providers aim to support patients in better managing their conditions while minimizing the impact of methotrexate-related complications.


What conditions Leucovorin Injection treats?

Leucovorin Injection is used to protect the body cells from the harmful effects of methotrexate, an anticancer medicine. It is essential in preventing and treating methotrexate overdose. It is administered slowly into the veins under doctor's supervision. The dosage and frequency will be determined by your doctor based on your condition. Common side effects include pain, swelling, and redness at the injection site. Regular blood tests are needed to monitor cell counts and methotrexate levels. Inform your doctor about any existing health conditions or medications.


Should you consult a doctor?

If you experience injection site reactions such as pain, swelling, or redness that bother you or seem severe, it's important to inform your doctor. Additionally, if you have seizures, liver, or kidney issues, or if you are taking medications for infections, consult your healthcare provider before starting Leucovorin Injection. Since various medicines can interact with this injection, including phenytoin for seizures, it is crucial to disclose all your current medications to your healthcare team. If you are pregnant or breastfeeding, it's essential to discuss this with your doctor before using this medicine. Regular blood tests are necessary to monitor your blood cells and serum methotrexate levels. Remember to take Leucovorin Injection exactly as prescribed to avoid serious side effects. If you notice persistent side effects or are concerned about any symptoms, seek medical advice promptly.


Side effects of Leucovorin Injection

When using Leucovorin Injection, you may experience side effects, although most of them do not typically need medical attention and tend to fade as your body gets used to the medication. However, it is essential to consult your doctor if the side effects persist or if you have concerns about them. Some common side effects associated with Leucovorin Injection include injection site reactions such as pain, swelling, and redness. If you notice any of these effects, it is advisable to inform your healthcare provider for further guidance.


Safety advice

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liver

Caution is advised when using Leucovorin Injection in patients with liver disease. Limited information is available regarding its use in such cases. It is important to consult with your doctor before using this medication to ensure its safety and effectiveness for individuals with liver issues.

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kidney

Limited information available on Leucovorin Injection use in patients with kidney disease. Consult doctor for guidance.

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alcohol

Consult your doctor when consuming alcohol with Leucovorin Injection.

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driving

"When using Leucovorin Injection, your ability to drive is typically unaffected."

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pregnancy

Leucovorin Injection may not be safe to use during pregnancy. Limited human studies suggest potential harm to the developing baby. Your doctor will assess the benefits and risks before prescribing. Please consult your doctor regarding this.

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breastfeeding

Information about using Leucovorin Injection during breastfeeding is not provided. Therefore, it is advised to consult your doctor regarding its safety during breastfeeding.


Consumption warning before consuming Leucovorin Injection

Before taking Leucovorin Injection, it is important to be aware of some precautions. This injection is primarily used to counteract the harmful effects of methotrexate and to treat methotrexate overdose. It should only be administered as a slow injection into the veins under the supervision of a doctor. Your doctor will determine the appropriate dosage and frequency based on your condition, so it is crucial to follow their instructions precisely. Taking the medication improperly or in excessive amounts can lead to severe side effects.


Common side effects of Leucovorin Injection include reactions at the injection site such as pain, swelling, and redness. If these symptoms become bothersome or worsen, inform your doctor promptly. Regular blood tests are necessary to monitor your blood cells and the concentration of methotrexate in your bloodstream.


Before beginning treatment with this injection, ensure your doctor is aware of any history of seizures, liver or kidney issues, or if you are taking medications for infections. It is important to disclose all medications you are currently using, particularly phenytoin for seizures, as interactions can occur. Pregnant or breastfeeding individuals should also inform their doctor to ensure the safety of taking this medication.


What if you forgot to take Leucovorin Injection?

If you forget to take your scheduled dose of Leucovorin Injection, try to take it as soon as you remember. But if it's almost time for your next dose, it's best to skip the missed one and continue with your usual dosing schedule. Avoid taking a double dose to make up for the missed one. It is important to follow the prescribed dosing instructions to maintain the effectiveness of the medication.


Additional Information

Habit FormingNo
Chemical ClassGlutamic Acid Derivatives
Therapeutic Class-
Action ClassCytoprotective agents- methotrexate

FAQs


Disclaimer

The information provided on this website is to the best of our abilities to ensure it is accurate, reliable, and reviewed by a team of professionals. It should not be used to diagnose, prevent, or cure any health problem. The information presented here is not intended to create a doctor-patient relationship or replace a registered medical practitioner's advice, diagnosis, or treatment. The absence or provision of any information or warning regarding any medicine should not be assumed as an implied or explicit assurance of safety or efficacy. We highly recommend consulting your registered medical practitioner for all queries or doubts related to your medical condition. Do not ignore professional medical advice or delay seeking it based on the content encountered on our website. We intend to support, not replace, the doctor-patient relationship.

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Dr. Gowri Kulkarni

MBBS - General Medicine, DNB - Psychiatry, MRCGP [INT] Family Medicine, BSIC (BACP)

Last update on 01-Oct-2024