Keygraf 1 Capsule

By Keygraf

Rx

10 Capsule in a Strip

Composition icon

Composition

Tacrolimus(1mg)

Manufacturer - Anthem Biopharma icon

Manufacturer - Anthem Biopharma

No 49, Canara Bank Road, Bommasandra Industrial Area, Phase 1, Hosur Road, Bangalore 560 099, Karnataka, India.

Expires on or after icon

Expires on or after

July, 2025

About Keygraf 1 Capsule

Keygraf 1 Capsule 10's is a type of medication classified as an immunosuppressant, specifically designed to be used in conjunction with other medicines to prevent the rejection of newly transplanted organs such as the liver, kidney, or heart. This capsule contains Tacrolimus, a substance that works by suppressing the activity of T and B lymphocytes in the immune system that would typically attack foreign invaders. By doing so, it helps the body in accepting the new organ and prevents rejection after transplantation.

When prescribed Keygraf 1 Capsule 10's, it is important to follow your doctor's instructions meticulously. The dosage, frequency, and duration of treatment will be determined based on the type of transplant, your body weight, and other medications you may be taking. To maximize the benefits, it is recommended to take the capsule on an empty stomach, at least 1 hour before or 2 hours after eating. Consistency in taking the medication is crucial even if you start feeling better, as discontinuing it could heighten the risk of organ rejection.

Despite its effectiveness, Keygraf 1 Capsule 10's does come with potential side effects that require careful attention. Some individuals might experience nausea, diarrhea, headaches, kidney problems, infections, constipation, or high blood pressure. While most of these side effects usually subside over time, it is essential to consult your doctor if they persist or worsen. This medication weakens your immune system, making you more susceptible to infections, which necessitates monitoring and frequent medical tests throughout the treatment period.

Prior to starting Keygraf 1 Capsule 10's, inform your doctor about any existing kidney, liver, or heart issues, diabetes, high blood pressure, or medications you are currently taking. Limiting exposure to sunlight and UV light is advised to reduce the risk of skin cancer as immunosuppressants can heighten this danger. It is crucial for both men and women using this medication to utilize effective birth control methods to prevent pregnancy, as Keygraf 1 Capsule 10's is generally not recommended during pregnancy or breastfeeding unless deemed absolutely necessary.

In conclusion, Keygraf 1 Capsule 10's offers valuable assistance in preventing organ rejection post-transplantation, with its mechanism of action centered around suppressing the immune system's response. However, the management of potential side effects and adherence to medical advice play crucial roles in the successful utilization of this medication.


Benefits

Keygraf 1 Capsule is a vital medicine that offers significant benefits in the prevention of organ rejection in transplant patients. When someone undergoes an organ transplant, there is a risk of organ rejection, where the body's immune system mistakes the new organ as a threat and launches an attack against it. Keygraf 1 Capsule, which contains Tacrolimus, functions as an immunosuppressant. It works by weakening the immune response that would normally fight off infections, thereby reducing the likelihood of the body rejecting the transplanted organ.


By targeting and suppressing the activity of T and B lymphocytes, which are essential components of the immune system responsible for identifying and attacking foreign invaders, Keygraf 1 Capsule plays a crucial role in helping the body accept the new organ. This action helps in protecting the transplanted organ and significantly reduces the chances of organ rejection in patients who have undergone transplant surgeries. It is essential to continue taking Keygraf 1 Capsule as prescribed by your doctor to ensure the success of the transplant operation.


In summary, Keygraf 1 Capsule is a valuable medication that, when used in combination with other medicines, enhances the likelihood of a successful transplant operation by effectively suppressing the immune response and safeguarding the transplanted organ from rejection. It offers transplant patients the opportunity to lead healthier lives post-surgery by ensuring the acceptance of the new organ and promoting better long-term outcomes. It is crucial to follow your doctor's recommendations and not discontinue the medication without medical advice to optimize the benefits of Keygraf 1 Capsule in preventing organ rejection.


How to use the Keygraf 1 Capsule

To use Keygraf 1 Capsule, follow your doctor's instructions carefully. Take the capsule on an empty stomach. Swallow the capsule whole with water, without crushing, breaking, or chewing it. If you have granules instead of a capsule, mix them with water to create an oral suspension. Drink the suspension right after preparing it; do not save it for later use. Always take the medicine as per the prescribed dose and duration to get the best results. If you have any questions about how to use Keygraf 1 Capsule, consult your doctor or pharmacist for guidance.


Uses of Keygraf 1 Capsule

The Keygraf 1 Capsule is primarily used to prevent organ rejection in transplant patients. This medication helps in stopping the body from rejecting transplanted organs, making it a crucial treatment for individuals who have undergone organ transplantation. By taking the Keygraf 1 Capsule as prescribed, patients can increase the chances of their new organs being accepted by their bodies and avoid the complications associated with organ rejection. This usage highlights the importance of Keygraf 1 Capsule in maintaining the health and well-being of transplant recipients.


What conditions Keygraf 1 Capsule treats?

Organ rejection happens when your body's defense system views a transplanted organ as unfamiliar and works to get rid of it. This rejection may occur swiftly (hyperacute), within the early months (acute), or later on (chronic). Symptoms can differ depending on the type of transplant you received, but pain, fever, or general sickness are common signs that you should promptly report to your doctor.


Should you consult a doctor?

If you are taking Keygraf 1 Capsule, it is important to seek medical attention if you experience certain symptoms. Contact your doctor immediately if you notice increased blood glucose levels, kidney damage, or persistent insomnia, tremors, high blood pressure, or signs of infection. These side effects require urgent medical attention as they may indicate serious complications that need to be addressed promptly. It is crucial to inform your healthcare provider about any concerning symptoms you may be experiencing while taking this medication to ensure proper management and monitoring of your health. Remember to follow your doctor's guidance closely, attend regular medical check-ups, and report any unusual or persistent side effects for timely intervention.


Side effects of Keygraf 1 Capsule

When taking Keygraf 1 Capsule, you may experience some side effects. Although most side effects are usually temporary and may go away as your body gets used to the medication, it is important to talk to your doctor if you have concerns or if the symptoms persist. Some potential side effects include increased glucose levels in the blood, kidney damage, insomnia (difficulty sleeping), tremors, high blood pressure, and the risk of infections. Additionally, you may also experience nausea, diarrhea, headache, constipation, fever, and kidney problems. It is essential to monitor your symptoms carefully and consult with your healthcare provider if you have any worries or if the side effects become troublesome.


Safety advice

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liver

When taking Keygraf 1 Capsule, it is important to be cautious if you have liver disease. Patients with liver issues may require adjustments to the dosage of the capsule. It is highly recommended to consult your doctor before using Keygraf 1 Capsule to ensure the appropriate dosage and safety for your liver health.

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kidney

Keygraf 1 Capsule requires caution in patients with kidney disease. Dosage adjustment might be necessary. Please consult your doctor.

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alcohol

It is not recommended to drink alcohol while taking Keygraf 1 Capsule due to safety concerns.

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driving

When taking Keygraf 1 Capsule, be cautious while driving as it may reduce alertness, impact vision, and cause drowsiness or dizziness. Avoid driving if experiencing these symptoms.

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pregnancy

Keygraf 1 Capsule could potentially be harmful during pregnancy based on animal studies. Limited human studies are available. Consult your doctor for a personalized assessment considering the risks and benefits before using this medication.

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breastfeeding

**Safety Advice - Breastfeeding** Keygraf 1 Capsule is considered unsafe during breastfeeding. Limited data suggests it may pass into breastmilk and harm the baby.


Consumption warning before consuming Keygraf 1 Capsule

Before taking Keygraf 1 Capsule, it's important to inform your doctor if you have any allergies to Tacrolimus or other medications. If you are pregnant or breastfeeding, consult your doctor before using this medication. It is advised to avoid consuming alcohol while on Keygraf 1 Capsule. Be cautious when driving as this medication may cause vision issues or nervous disturbances in some individuals. Notify your doctor if you are due to receive a vaccination while taking Keygraf 1 Capsule. This medication can lower your body's immune defenses, potentially increasing the risk of infections or skin cancer. When outdoors, protect yourself by wearing appropriate clothing and using sunscreen. To prepare the oral suspension, use glass or metal materials and avoid plastics as granules can stick, affecting the dose. If accidental contact occurs with the skin, wash the area thoroughly with soap and water. Rinse eyes with plain water if contact happens.


What if you forgot to take Keygraf 1 Capsule?

If you forget to take a dose of Keygraf 1 Capsule, try to take it as soon as you remember. But if it's nearly time for your next scheduled dose, it's better to skip the missed dose and continue with your usual dosing routine. Remember not to take a double dose to make up for the missed one. It's important to stay consistent with your medication schedule.


Additional Information

Habit FormingNo
Chemical ClassMacrolide Lactams
Therapeutic Class-
Action ClassImmunosuppressant- Calcineurin inhibitors

FAQs


Disclaimer

The information provided on this website is to the best of our abilities to ensure it is accurate, reliable, and reviewed by a team of professionals. It should not be used to diagnose, prevent, or cure any health problem. The information presented here is not intended to create a doctor-patient relationship or replace a registered medical practitioner's advice, diagnosis, or treatment. The absence or provision of any information or warning regarding any medicine should not be assumed as an implied or explicit assurance of safety or efficacy. We highly recommend consulting your registered medical practitioner for all queries or doubts related to your medical condition. Do not ignore professional medical advice or delay seeking it based on the content encountered on our website. We intend to support, not replace, the doctor-patient relationship.

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Dr. Archana Prabhakar

MBBS, M.Med (Family Medicine)

Last update on 01-Oct-2024