Janumet 50mg/1000mg Tablet

By Janumet

Rx

15 Tablet in a Strip

Composition icon

Composition

Sitagliptin(50mg) + Metformin(1000mg)

Manufacturer - MSD Pharmaceuticals Pvt Ltd icon

Manufacturer - MSD Pharmaceuticals Pvt Ltd

Platina, 8th Floor, C.59, G Block, Bandra Kurla Complex, Bandra (East) , Mumbai - 400098,

Expires on or after icon

Expires on or after

October, 2025

About Janumet 50mg/1000mg Tablet

Janumet 50mg/1000mg Tablet is a combined medication used to manage high blood sugar levels in individuals with type 2 diabetes mellitus. The tablet contains Sitagliptin and Metformin, which are classified as DPP-4 inhibitors and biguanides, respectively. Type 2 diabetes occurs when the body either does not produce enough insulin or becomes resistant to its effects, leading to high blood sugar levels. Sitagliptin helps by increasing certain natural substances that lower blood sugar levels, while Metformin works by reducing glucose production in the liver, delaying glucose absorption from the intestines, and enhancing the body's sensitivity to insulin.

It is essential to take Janumet 50mg/1000mg Tablet with food to avoid stomach discomfort. Consistency is key, so it should be taken at the same time each day for optimal results. Your doctor will determine the appropriate dosage based on your condition, blood sugar levels, and other medications you may be taking. It is crucial to adhere to the prescribed regimen and not discontinue the medication without consulting your doctor, as fluctuations in blood sugar levels can lead to complications such as kidney damage, blindness, heart attacks, or strokes.

Common side effects of Janumet 50mg/1000mg Tablet may include diarrhea, nausea, vomiting, headache, and sore throat. Hypoglycemia, characterized by symptoms like dizziness, sweating, and hunger pangs, is also a potential side effect, especially when combined with other diabetes medications. To mitigate the risk of hypoglycemia, it is advised not to skip meals and to carry a quick sugar source with you. Individuals with kidney, liver, or heart issues, as well as pregnant or breastfeeding women, should inform their doctors before starting Janumet 50mg/1000mg Tablet. Additionally, alcohol consumption should be minimized, as it can lower blood glucose levels. Regular monitoring of kidney function and blood sugar levels is necessary during treatment to ensure safety and efficacy.


Benefits

Janumet 50mg/1000mg Tablet offers several benefits for individuals dealing with Type 2 diabetes mellitus. This medication is a combination of two medicines that work together to lower blood glucose levels, which is crucial in managing diabetes effectively. By controlling blood glucose levels, the risk of developing serious complications associated with diabetes, such as kidney damage, eye damage, nerve problems, and loss of limbs, is significantly reduced. Furthermore, maintaining proper control of diabetes also lowers the risk of heart disease and stroke.


Janumet 50mg/1000mg Tablet helps the pancreas produce more insulin, enhances the body's ability to utilize insulin efficiently, and reduces the excess sugar produced by the liver. By controlling the rise in blood sugar levels after meals, this medication plays a crucial role in regulating overall blood sugar levels. Importantly, Janumet 50mg/1000mg Tablet does not lead to weight gain with prolonged use, making it a favorable option for long-term management of diabetes.


In addition to lowering blood sugar levels, Janumet 50mg/1000mg Tablet also helps prevent the development of serious diabetes-related complications such as eyesight loss (retinopathy), kidney damage (nephropathy), nerve damage (neuropathy), diabetic foot ulcers, and delayed wound healing. By taking this medication regularly as prescribed, along with maintaining a proper diet and engaging in regular exercise, individuals with diabetes can significantly improve their overall health and quality of life. It is important to continue using Janumet 50mg/1000mg Tablet as directed by a healthcare professional to ensure ongoing protection of future health and well-being.


How to use the Janumet 50mg/1000mg Tablet

To use Janumet 50mg/1000mg Tablet, follow your doctor's instructions on dosage and duration. Swallow the tablet whole with a glass of water. It is important not to crush, chew, or break the tablet. Take Janumet 50mg/1000mg Tablet with food, preferably after meals, or as directed by your physician. Your doctor will determine the right dosage and duration based on factors like your age, weight, and the condition being treated. Do not stop taking Janumet 50mg/1000mg Tablet unless advised by your doctor. Remember, always follow your healthcare provider's guidance while using this medication.


Uses of Janumet 50mg/1000mg Tablet

Janumet 50mg/1000mg Tablet is primarily used for the treatment of Type 2 diabetes mellitus, a condition that affects blood sugar control in the body. This medication is specifically designed to help manage Type 2 diabetes mellitus, a common chronic illness that requires careful management of blood sugar levels. Janumet 50mg/1000mg Tablet is an important tool in the treatment plan for individuals with Type 2 diabetes mellitus, as it helps to regulate blood sugar levels effectively.


What conditions Janumet 50mg/1000mg Tablet treats?

Janumet 50mg/1000mg Tablet is used to help manage Type 2 diabetes, a condition characterized by the body's inability to produce enough insulin or effectively use the insulin it produces. This leads to high blood sugar levels, resulting in symptoms like increased thirst, frequent urination, slow wound healing, increased hunger, fatigue, and blurred vision. Type 2 diabetes can also lead to complications such as neuropathy, nephropathy, retinopathy, limb loss, sexual dysfunction, and an increased risk of heart attack or stroke.


Should you consult a doctor?

If you experience severe, uncontrollable diabetes, nausea, vomiting, diarrhea, rapid weight loss, lactic acidosis, ketoacidosis, dehydration, severe systemic infection, shock, blood circulation problems, breathing difficulties, alcoholism, or are scheduled for upcoming X-rays, do not use Janumet 50mg/1000mg Tablet. Inform your doctor if you have a history of pancreatitis, alcohol dependence, high blood lipid levels, type I diabetes, upcoming major surgery, fasting, malnutrition, extreme muscle exercises, or a vitamin B12 deficiency before taking this medication. If any of these conditions apply to you, consult your healthcare provider before using this medication to ensure your safety and well-being.


Side effects of Janumet 50mg/1000mg Tablet

Side effects of Janumet 50mg/1000mg Tablet can vary from mild to severe. Some common side effects that may occur but usually do not require medical attention include decreased appetite, vomiting, upper respiratory tract infection, hypoglycemia (low blood sugar), abdominal bloating, nausea, diarrhea, runny nose, sore throat, among others. These side effects typically fade away as your body gets used to the medication. However, if any of these symptoms persist or cause concern, it is advisable to consult your doctor promptly.


More serious side effects may also occur, although they are rare. If you experience a serious allergic reaction such as hives, swelling of the face, lips, tongue, or throat leading to difficulty breathing or swallowing, stop taking Janumet 50mg/1000mg Tablet immediately and seek medical help. Additionally, severe blistering of the skin, signs of pancreatitis like persistent stomach pain, signs of lactic acidosis including dizziness or lightheadedness, weakness, trouble breathing, unusual muscle pain, or signs of hypoglycemia such as nausea, vomiting, and low blood sugar levels require immediate medical attention.


Other severe side effects that should be reported to your doctor include flatulence, diarrhea, constipation, stomach pain, loss of appetite, swelling of the hands and legs (edema), upper respiratory infections, stuffy nose, sore throat, joint pain, pain in the arms or legs, metallic taste, among others. Always be vigilant for any unusual or severe symptoms while taking Janumet 50mg/1000mg Tablet and consult your healthcare provider if any alarming side effects occur as your safety and well-being are paramount.


Safety advice

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liver

Janumet 50mg/1000mg Tablet may not be safe for individuals with liver disease and it is recommended to avoid its use in such cases. If you have any liver-related conditions, a history of liver problems, or any signs of liver disease, it is crucial to consult your doctor before taking this medication. Your doctor will be able to provide you with the best guidance and advice based on your specific liver health status.

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kidney

Janumet 50mg/1000mg Tablet needs caution in patients with kidney disease. Consult your doctor for dose adjustments. Not recommended for severe kidney disease. Monitor kidney function regularly while using this medicine. If you have kidney issues, consult your doctor before taking Janumet 50mg/1000mg Tablet.

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alcohol

It is advised to avoid consuming alcohol while taking Janumet 50mg/1000mg Tablet to ensure safety and effectiveness of the treatment.

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driving

When taking Janumet 50mg/1000mg Tablet, avoid driving if experiencing symptoms of low or high blood sugar. Drive only when physically stable and mentally focused. If drowsiness occurs, refrain from driving or operating machinery.

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pregnancy

Janumet 50mg/1000mg Tablet may not be safe to use during pregnancy. Limited human studies show possible harm to the baby. Animal studies demonstrated negative effects. Your doctor will consider benefits versus risks before prescribing. Seek doctor's advice before use.

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breastfeeding

Janumet 50mg/1000mg Tablet may not be safe for breastfeeding as it can pass into breastmilk and harm the baby. Use only if benefits outweigh risks; consult your doctor before using it.


Age above 75(Geriatrics)

Janumet 50mg/1000mg Tablet should be used with caution in elderly patients (aged above 65 years). Therefore, consult your doctor before taking it.


Age below 6 months(Pediatrics)

Janumet 50mg/1000mg Tablet is not recommended for use in children and adolescents (aged below 18 years). However, consult your doctor before taking it.


Consumption warning before consuming Janumet 50mg/1000mg Tablet

Before consuming Janumet 50mg/1000mg Tablet, it is important to note certain warnings. Patients with type 1 diabetes or diabetic ketoacidosis should avoid using this medication. There is a risk of developing lactic acidosis, a serious condition where too much lactic acid builds up in the blood, potentially impacting the liver and kidneys. Prior to starting Janumet 50mg/1000mg Tablet, inform your doctor if you have a history of pancreatitis, kidney disease, or low vitamin B12 levels. When combined with insulin, the medication may lower blood sugar levels, leading to hypoglycemia, a potentially fatal condition. Regular monitoring of thyroid-stimulating hormone (TSH) levels is advised due to possible TSH reduction with prolonged use. Additionally, rare cases of bullous pemphigoid, a serious skin reaction, have been reported. It is crucial to inform your doctor if undergoing tests with dye or X-ray contrast agents and temporarily discontinue Janumet 50mg/1000mg Tablet before X-ray procedures.


Disease interactions

Individuals with heart diseases such as congestive heart failure or myocardial infarction, as well as those with Vitamin B12 deficiency or alcoholism, should exercise caution when considering the use of Janumet 50mg/1000mg Tablet. It is advisable for these individuals to avoid taking this medication due to potential interactions that may exacerbate their existing conditions. It is important to consult a healthcare professional before using Janumet 50mg/1000mg Tablet if you have any of these health concerns to ensure the safest and most appropriate treatment plan for your specific medical condition.


What if you forgot to take Janumet 50mg/1000mg Tablet?

If you forget to take your Janumet 50mg/1000mg Tablet, you should take it as soon as you remember. But if it's nearly time for your next dose, just skip the missed dose and continue with your regular dosing schedule. Remember not to take a double dose to make up for the missed one. This will help maintain the proper balance of medication in your system and minimize any potential side effects.


What happens if you take overdose of Janumet 50mg/1000mg Tablet?

In case of an accidental overdose of Janumet 50mg/1000mg Tablet, quick action is essential. If you or someone else takes more than the prescribed amount, seek medical help promptly by contacting your doctor or heading to the nearest hospital. Signs of an overdose may include feeling cold or uneasy, intense nausea or vomiting, stomach discomfort, unexplained weight loss, muscle cramps, and rapid breathing.


Related lab tests

Related Lab Tests for monitoring diabetes in patients taking Janumet 50mg/1000mg Tablet may include Blood Glucose - Fasting and Postprandial tests. These tests help measure the sugar levels in the blood before and after meals. Another important test is Glycosylated Hemoglobin (HbA1C), also known as Hemoglobin A1C. This test provides an average of your blood sugar levels over the past two to three months. Monitoring these lab tests regularly can help in managing diabetes and evaluating the effectiveness of the medication. Other relevant lab tests may include Random Blood Sugar (RBS), Insulin-Fasting, and Insulin Postprandial (PP) tests to further assess insulin levels in the body. Additionally, Vital Diabetes Care, Extended Diabetes Care, Advance Diabetes Care, and Comprehensive Diabetes Care tests may be recommended for a more detailed evaluation of overall diabetes management. Regular monitoring of these lab tests is essential for optimizing treatment and improving outcomes for individuals with diabetes.


Additional Information

Habit FormingNo
Chemical Class-
Therapeutic ClassANTI DIABETIC
Action Class-

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Disclaimer

The information provided on this website is to the best of our abilities to ensure it is accurate, reliable, and reviewed by a team of professionals. It should not be used to diagnose, prevent, or cure any health problem. The information presented here is not intended to create a doctor-patient relationship or replace a registered medical practitioner's advice, diagnosis, or treatment. The absence or provision of any information or warning regarding any medicine should not be assumed as an implied or explicit assurance of safety or efficacy. We highly recommend consulting your registered medical practitioner for all queries or doubts related to your medical condition. Do not ignore professional medical advice or delay seeking it based on the content encountered on our website. We intend to support, not replace, the doctor-patient relationship.

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Dr. Upasana Bhatia

MBBS - General Medicine

Last update on 18-Nov-2024