Istamet XR 500 Tablet

By Istamet

Rx

15 Tablet in a Strip

Composition icon

Composition

Sitagliptin(100mg) + Metformin(500mg)

Manufacturer - Sun Pharmaceutical Industries Ltd icon

Manufacturer - Sun Pharmaceutical Industries Ltd

Plot no 107/108,Namli block , Ranipool, East Sikkim 737135

Expires on or after icon

Expires on or after

April, 2026

Benefits

Istamet XR 500 Tablet offers a range of benefits for individuals dealing with Type 2 diabetes mellitus. This medication is a combination of two medicines that work in harmony to lower blood glucose levels, a crucial aspect of managing diabetes. By maintaining control over your blood glucose levels with the help of Istamet XR 500 Tablet, you can significantly reduce the risk of developing serious complications associated with diabetes such as kidney damage, eye damage, nerve problems, and even loss of limbs.


Moreover, proper management of diabetes through the consistent use of Istamet XR 500 Tablet and adherence to a balanced diet and regular exercise routine can also decrease the likelihood of heart disease and strokes. Istamet XR 500 Tablet aids in boosting insulin production by the pancreas, improving insulin utilization, and reducing the excess sugar produced by the liver. It effectively regulates blood sugar levels post meals without causing weight gain during prolonged use.


Additionally, this medication plays a crucial role in preventing severe diabetes-related complications including eyesight loss (retinopathy), kidney issues (nephropathy), nerve damage (neuropathy), diabetic foot ulcers, and delayed wound healing. By incorporating Istamet XR 500 Tablet into your daily routine as prescribed, you take proactive steps towards safeguarding your future health and well-being, ultimately paving the way for a normal and healthy life.


How to use the Istamet XR 500 Tablet

To use Istamet XR 500 Tablet, follow the instructions provided by your doctor carefully. It is important to take the medicine in the dosage and duration prescribed by your doctor. Swallow the tablet whole with a glass of water. Avoid crushing, chewing, or breaking the tablet. It is recommended to take Istamet XR 500 Tablet with food.


Ideally, take the tablet after meals or as directed by your physician. Your doctor will determine the appropriate dose and duration of treatment based on factors such as your age, body weight, and the severity of your condition. Do not stop taking Istamet XR 500 Tablet unless advised by your doctor to do so. Following these guidelines will help ensure the effectiveness of the medication in managing your condition.


Uses of Istamet XR 500 Tablet

Istamet XR 500 Tablet is primarily used for the treatment of Type 2 diabetes mellitus, a condition characterized by high blood sugar levels resulting from the body's inability to properly utilize insulin. This medication is specifically designed to help manage type II diabetes mellitus, a chronic metabolic disorder that typically requires ongoing medical intervention to control blood sugar levels. By providing a combination of 100mg and 500mg doses, Istamet XR 500 Tablet aims to help patients maintain optimal blood glucose levels. It is essential to follow your healthcare provider's instructions carefully when using this medication to effectively manage Type 2 diabetes mellitus.


What conditions Istamet XR 500 Tablet treats?

Type 2 diabetes is a condition where the body struggles to produce enough insulin or effectively use the insulin it creates, leading to high blood sugar levels. Symptoms can include increased thirst, frequent urination, slow wound healing, heightened hunger, fatigue, blurred vision, and possible weight changes. Complications of type 2 diabetes may involve neuropathy, nephropathy, retinopathy, limb loss, sexual issues, and a higher risk of heart attack or stroke.


Should you consult a doctor?

When taking Istamet XR 500 Tablet, it is crucial to seek medical advice if you experience severe, uncontrollable diabetes, nausea, vomiting, diarrhea, or rapid weight loss. Additionally, if you have conditions such as lactic acidosis, ketoacidosis, dehydration, severe systemic infection, shock, blood circulation issues, breathing problems, alcoholism, or upcoming X-rays, consulting a doctor is necessary. Before starting this medication, inform your healthcare provider if you have a history of pancreatitis, alcohol dependency, high blood lipid levels, type I diabetes, upcoming major surgery, fasting, malnutrition, extreme muscle exercises, or vitamin B12 deficiency. Seeking medical attention promptly in such situations is important to ensure your health and safety.


Side effects of Istamet XR 500 Tablet

When taking Istamet XR 500 Tablet, you may experience some side effects. Most of these side effects are not severe and may go away as your body gets used to the medication. These could include decreased appetite, vomiting, upper respiratory tract infections, hypoglycemia (low blood sugar), abdominal bloating, nausea, and diarrhea. Additionally, some common side effects may manifest as runny nose, sore throat, upper lung infections, dizziness, dry mouth, and headache. If you encounter more serious side effects, such as a severe allergic reaction (like hives, swelling of face, lips, tongue, or throat causing breathing difficulties), severe blistering of the skin (indicating allergic skin reaction), signs of pancreatitis (persistent stomach pain with or without nausea and vomiting), or signs of lactic acidosis (cold hands or feet, irregular heartbeat, unusual muscle pain, etc.), stop taking the medication immediately and consult your doctor. Other severe side effects could include swelling of the hands and legs, joint pain, metallic taste, and other gastrointestinal issues like flatulence, constipation, and loss of appetite. It is essential to seek medical advice if any of these serious side effects occur.


Safety advice

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liver

Istamet XR 500 Tablet may not be safe for patients with liver disease and should be avoided. It is recommended that you consult your doctor before using this medication if you have any liver issues.

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kidney

Istamet XR 500 Tablet should be used cautiously in patients with kidney disease. Dose adjustment may be necessary and regular kidney function tests are recommended. Avoid using in severe kidney disease. Remember to consult your doctor for guidance.

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alcohol

It is not safe to drink alcohol while taking Istamet XR 500 Tablet.

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driving

When taking Istamet XR 500 Tablet, do not drive if you experience symptoms of low or high blood sugar that affect your focus and reaction time. It is important to prioritize safety on the road.

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pregnancy

Istamet XR 500 Tablet may be harmful during pregnancy. Animal studies suggest it could harm the developing baby. Consult your doctor for advice on the potential risks and benefits before taking this medication.

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breastfeeding

Istamet XR 500 Tablet may not be safe while breastfeeding. Limited data shows potential harm to the baby through breastmilk.


Age above 75(Geriatrics)

Istamet XR 500 Tablet should be used with caution in elderly patients (aged above 65 years). Therefore, consult your doctor before taking it.


Age below 6 months(Pediatrics)

Istamet XR 500 Tablet is not recommended for use in children and adolescents (aged below 18 years). However, consult your doctor before taking it.


Consumption warning before consuming Istamet XR 500 Tablet

Before consuming Istamet XR 500 Tablet, it is important to note several warnings to ensure your safety and well-being. This medication is not suitable for individuals with type 1 diabetes or diabetic ketoacidosis. Some diabetic patients may experience lactic acidosis while taking Istamet XR 500 Tablet, a serious condition that can harm the liver and kidneys. Inform your doctor if you have a history of pancreatitis, kidney disease, or low vitamin B12 levels before starting this medication.


When using Istamet XR 500 Tablet alongside insulin, be cautious as it may reduce blood sugar levels, potentially leading to hypoglycemia. Regular monitoring and dosage adjustment by your doctor may be necessary. Long-term use of this medication can lower thyroid-stimulating hormone levels, so it's advised to undergo annual TSH check-ups. In rare instances, a severe skin reaction known as bullous pemphigoid may occur, requiring immediate medical intervention. Additionally, inform your doctor if you are scheduled for a diagnostic test involving dye or X-ray contrast agents, as temporary cessation of Istamet XR 500 Tablet may be necessary prior to the procedure.


Disease interactions

Individuals with certain health conditions must exercise caution when considering the use of Istamet XR 500 Tablet. Specifically, those with heart diseases such as congestive heart failure and myocardial infarction, Vitamin B12 deficiency, and alcoholism are advised to avoid taking this medication. It is important for individuals affected by these conditions to consult their healthcare provider before starting any new medication, including Istamet XR 500 Tablet, to ensure safety and efficacy of treatment.


What if you forgot to take Istamet XR 500 Tablet?

If you forget to take a dose of Istamet XR 500 Tablet, try to take it as soon as you remember. But if it's nearly time for your next dose, just skip the missed one and continue with your usual dosing schedule. Remember not to double the dose to make up for the missed one.


What happens if you take overdose of Istamet XR 500 Tablet?

In case of an accidental overdose of Istamet XR 500 Tablet, it is crucial to seek immediate medical assistance. Overdose symptoms may include feeling cold or uncomfortable, severe nausea or vomiting, stomach pain, unexplained weight loss, muscular cramps, and rapid breathing. If you or someone you know experiences any of these symptoms after taking more than the prescribed dose of Istamet XR 500 Tablet, do not hesitate to consult a doctor or visit the nearest hospital for prompt treatment.


Related lab tests

Related Lab Tests for monitoring the use of Istamet XR 500 Tablet include:


1. Blood Glucose - Fasting: This test measures the level of glucose in your blood after fasting for several hours. It helps in assessing overall blood sugar control.


2. Blood Glucose - Postprandial: This test measures the level of glucose in your blood after a meal. It provides information on how your body is processing glucose after eating.


3. HbA1C (Glycosylated Hemoglobin): This test gives an average of your blood sugar levels over the past 2-3 months. It is an important indicator of long-term glucose control.


Regular monitoring of these lab tests can help in managing diabetes and assessing the effectiveness of Istamet XR 500 Tablet in controlling blood sugar levels.


Additional Information

Habit FormingNo
Chemical Class-
Therapeutic ClassANTI DIABETIC
Action Class-

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Disclaimer

The information provided on this website is to the best of our abilities to ensure it is accurate, reliable, and reviewed by a team of professionals. It should not be used to diagnose, prevent, or cure any health problem. The information presented here is not intended to create a doctor-patient relationship or replace a registered medical practitioner's advice, diagnosis, or treatment. The absence or provision of any information or warning regarding any medicine should not be assumed as an implied or explicit assurance of safety or efficacy. We highly recommend consulting your registered medical practitioner for all queries or doubts related to your medical condition. Do not ignore professional medical advice or delay seeking it based on the content encountered on our website. We intend to support, not replace, the doctor-patient relationship.

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Dr. Gowri Kulkarni

MBBS - General Medicine, DNB - Psychiatry, MRCGP [INT] Family Medicine, BSIC (BACP)

Last update on 01-Oct-2024