Grafnos 0.25mg Capsule

By Grafnos

Rx

10 Capsule in a Strip

Composition icon

Composition

Tacrolimus(0.25mg)

Manufacturer - Akognos Life Sciences icon

Manufacturer - Akognos Life Sciences

Corporate & Registered Office, Akognos Life Sciences Pvt. Ltd., Manish Plaza, Third Floor, Plot No. 25, Sector-20 , Dwarka, New Delhi -110075

Expires on or after icon

Expires on or after

July, 2025

About Grafnos 0.25mg Capsule

Grafnos 0.25mg Capsule is a medication that is prescribed alongside other drugs to help prevent the rejection of a newly transplanted organ in the body, such as a liver, kidney, or heart. It works by weakening the immune system, which in turn stops it from attacking the new organ. This medicine falls into a category of drugs called immunosuppressants.

The dosage of Grafnos 0.25mg Capsule and the frequency of intake will vary depending on the type of organ transplant undergone, your body weight, and other medications you are currently taking. It is crucial to carefully follow your doctor’s instructions. It is recommended to take this medication on an empty stomach, at least 1 hour before or 2 hours after a meal. Consistency in taking the medicine is important to gain maximum benefits, even if you are feeling well. Stopping the medication abruptly may heighten the risk of rejecting the transplanted organ.

Like any medication, Grafnos 0.25mg Capsule comes with potential side effects that may require immediate attention. These include the possibility of developing or worsening diabetes and kidney issues. Other common side effects to watch out for are tremors, vulnerabilities to infections, high blood pressure, and insomnia. It is crucial to inform your doctor if these side effects persist or worsen. This medication lowers your body's immune system, increasing your susceptibility to infections.

Before starting this medication, inform your doctor if you have any pre-existing conditions such as kidney, liver, or heart problems, diabetes, or high blood pressure. Also, disclose any other medications you are currently taking, especially those for infections, pain, and arthritis, as they may interact with Grafnos 0.25mg Capsule. Additionally, it is advised to minimize sun exposure and UV light as immunosuppressants may heighten the risk of skin cancer.

Both men and women using Grafnos 0.25mg Capsule should practice effective birth control methods to avoid pregnancy. Generally, this medicine is not recommended during pregnancy or breastfeeding unless absolutely necessary. Regular medical tests are usually required before and during treatment to monitor your progress, and your blood pressure should be checked frequently.


Benefits

Grafnos 0.25mg Capsule, a medication that falls under the category of immunosuppressants, plays a crucial role in preventing organ rejection in transplant patients. Organ rejection occurs when the immune system identifies the new organ as a threat and launches an attack against it. By weakening the immune response, which typically fights infections, this medication significantly reduces the risk of the body rejecting the transplanted organ. Working in conjunction with other medicines, Grafnos 0.25mg Capsule enhances the success rate of transplant operations. It contains Tacrolimus, an immunosuppressant that targets the T and B lymphocytes - key players in the immune system's defense mechanism against foreign substances. By suppressing the activity of these cells, which would normally target foreign invaders, Grafnos 0.25mg Capsule facilitates the body's acceptance of the new organ and effectively prevents organ rejection in patients who have undergone organ transplants. It is important to adhere to the prescribed dosage and continue taking the medication until advised otherwise by a healthcare professional.


How to use the Grafnos 0.25mg Capsule

To use Grafnos 0.25mg Capsule, follow your doctor's instructions on the dose and duration. It's important to take this medicine on an empty stomach. If you are taking the capsule form, swallow it whole with water. Do not crush, break, or chew the capsule. If you are taking the granules, mix them with water to create an oral suspension. Drink the suspension immediately and do not store it for later use.

Take Grafnos 0.25mg Capsule 1 hour before meals or 2-3 hours after meals, or as directed by your physician. Swallow the capsule with a glass of water and do not crush or chew it. Your doctor will determine the right dose and duration of therapy based on factors like your age, body weight, and medical condition. It's important not to stop taking Grafnos 0.25mg Capsule without consulting your doctor first.


Uses of Grafnos 0.25mg Capsule

The primary use of Grafnos 0.25mg Capsule is for preventing organ rejection in transplant patients. It helps in preventing the rejection of transplanted organs, ensuring the body does not attack the newly transplanted organ. Grafnos 0.25mg Capsule is also effective in preventing graft rejection that may occur after an organ transplantation procedure. By taking this medication as prescribed, transplant patients can help maintain the functionality and health of their transplanted organ.


What conditions Grafnos 0.25mg Capsule treats?

Organ rejection is a condition where the body's immune system sees a transplanted organ as foreign and reacts to get rid of it. It can happen quickly (hyperacute), within a few months (acute), or after a year or more (chronic). Symptoms differ based on the organ transplanted but include pain, fever, and feeling unwell. If you notice these signs, seek medical help right away.


Should you consult a doctor?

It is important to seek advice from your doctor before taking Grafnos 0.25mg Capsule if you have upcoming vaccination schedules. Notify your doctor if you have high blood cholesterol or potassium levels. If you experience any unexpected or severe side effects while taking this medication, consult your doctor immediately for guidance and proper evaluation. Your doctor will be able to provide you with the necessary support and advice to ensure your well-being while taking Grafnos 0.25mg Capsule.


Side effects of Grafnos 0.25mg Capsule

When taking Tacrograf 0.25 Capsules, some common side effects may occur as your body gets used to the medication. These include increased blood sugar levels, kidney damage, difficulty sleeping, tremors, high blood pressure, and the risk of infections. Other potential side effects to be aware of are nausea, diarrhea, headache, constipation, fever, and further kidney problems. Additionally, some individuals may experience liver problems, feeling shaky, stomach issues, mouth ulcers, changes in blood cholesterol levels, or emotional symptoms like anxiety or depression. Physical effects may include skin rash, muscle pain, weight gain, and changes in vision or hearing sensitivity. It is important to contact your healthcare provider if you notice severe stomach pain, signs of skin or lymph cancer, increased infections, flu-like symptoms, signs of brain infection, kidney damage symptoms, vision changes, allergic reactions, or signs of heart problems while taking this medication.


Safety advice

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liver

For individuals with liver disease, caution is advised when using Grafnos 0.25mg Capsule. It may be necessary to adjust the dose of the medication. It is important to consult your doctor before taking Grafnos 0.25mg Capsule if you have any liver-related issues.

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kidney

Grafnos 0.25mg Capsule requires caution in patients with kidney disease. Adjusting the dose might be necessary. Always consult your doctor for guidance.

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alcohol

It is unsafe to drink alcohol while taking Grafnos 0.25mg Capsule. Drinking alcohol can have negative effects when combined with this medication.

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driving

When taking Grafnos 0.25mg Capsule, be cautious while driving. This medication may reduce alertness, impact vision, and cause drowsiness or dizziness. Avoid driving if you experience these effects.

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pregnancy

Grafnos 0.25mg Capsule may not be safe during pregnancy. Animal studies have shown potential harm to the developing baby. Your doctor will assess the risks and benefits before prescribing this medication. Consult your doctor for advice.

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breastfeeding

Caution is advised when using Grafnos 0.25mg Capsule during breastfeeding. Limited data indicates potential harm to the baby via breastmilk.


Age above 75(Geriatrics)

TACROGRAF 0.25MG CAPSULE should be used with caution in elderly patients. Therefore, consult your doctor before taking it.

Age below 6 months(Pediatrics)

The safety and effectiveness of TACROGRAF 0.25MG CAPSULE have not been established in children and adolescents (aged below 18 years) undergoing transplantation. Therefore, consult your doctor before taking it.

Consumption warning before consuming Grafnos 0.25mg Capsule

Before consuming Grafnos 0.25mg Capsule, it is essential to inform your doctor about any allergies to Tacrolimus or other medications. Pregnant or breastfeeding women should consult a doctor before using this medication. Avoid alcohol while taking Grafnos 0.25mg Capsule. Only drive if fully alert, as it may affect vision or cause nervous disturbances in some individuals. Notify your doctor if you are due for a vaccination before starting Grafnos 0.25mg Capsule, as it may impact your immune system and increase infection or skin cancer risks. When outdoors, wear protective clothing and sunscreen while using this medication. To prepare the oral suspension, opt for glass or metal materials to avoid the granules sticking to plastic containers, ensuring the full dose for children. Take precaution not to inhale or allow skin or eye contact with the granules or prepared suspension. If accidental contact occurs, wash the area with soap and water or rinse eyes with plain water.


What if you forgot to take Grafnos 0.25mg Capsule?

If you forget to take your Grafnos 0.25mg Capsule, try to take it as soon as you remember. But if it's close to the time for your next dose, just skip the missed dose. It's important not to take a double dose to make up for the one you missed. Stick to your usual schedule.


What happens if you take overdose of Grafnos 0.25mg Capsule?

In the event that you or someone else takes more than the prescribed amount of Tacrograf 0.25mg Capsule, it is crucial to seek prompt medical attention. Overdose symptoms may manifest as tremors, abnormal kidney function resulting in reduced or absent urine output, elevated blood pressure, leg swelling, and feelings of fatigue. It is important not to delay in contacting your doctor or visiting the nearest hospital if overdose is suspected.


Additional Information

Habit FormingNo
Chemical ClassMacrolide Lactams
Therapeutic Class-
Action ClassImmunosuppressant- Calcineurin inhibitors

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Disclaimer

The information provided on this website is to the best of our abilities to ensure it is accurate, reliable, and reviewed by a team of professionals. It should not be used to diagnose, prevent, or cure any health problem. The information presented here is not intended to create a doctor-patient relationship or replace a registered medical practitioner's advice, diagnosis, or treatment. The absence or provision of any information or warning regarding any medicine should not be assumed as an implied or explicit assurance of safety or efficacy. We highly recommend consulting your registered medical practitioner for all queries or doubts related to your medical condition. Do not ignore professional medical advice or delay seeking it based on the content encountered on our website. We intend to support, not replace, the doctor-patient relationship.

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Dr. Archana Prabhakar

MBBS, M.Med (Family Medicine)

Last update on 01-Oct-2024