Fragmin 5000IU Injection

By Fragmin

Rx

0ml Solution for Injection in a Prefilled syringe

Composition icon

Composition

Dalteparin(5000IU)

Manufacturer - Pfizer Ltd icon

Manufacturer - Pfizer Ltd

The Capital, 1802, 18th Floor , Plot No. C-70, 'G' Block , Bandra Kurla Complex, Bandra East , Mumbai – 400051.

Expires on or after icon

Expires on or after

July, 2025

About Fragmin 5000IU Injection

Fragmin 5000IU Injection is an anticoagulant medication used to prevent harmful blood clots from forming or getting larger in various parts of the body such as the legs, lungs, brain, or heart. This helps to reduce the risk of conditions like acute coronary syndrome, deep vein thrombosis, and pulmonary embolism. The medicine is administered by a doctor based on factors like your medical condition, response to treatment, age, and weight. It is crucial to continue using Fragmin 5000IU even if you feel fine, as stopping the medication abruptly could lead to the formation of blood clots.

The active ingredient in Fragmin 5000IU Injection is Dalteparin, which belongs to a class of drugs known as anticoagulants or blood thinners. It works by inhibiting the production of clotting factors Xa and thrombin, which prevents the formation of harmful blood clots. By making blood flow more easily through the veins, Fragmin 5000IU helps lower the risk of serious clot-related complications like heart attacks or strokes. Patients with conditions such as atrial fibrillation, deep vein thrombosis, or pulmonary embolism may benefit from the preventive effects of Fragmin 5000IU Injection.

Common side effects of Fragmin 5000IU Injection include bleeding, injection site reactions like redness, swelling, and pain, as well as symptoms that might indicate internal bleeding such as uncontrolled bleeding gums. It's important to notify your doctor if you experience severe headaches or stomach aches while on this medication, as they could be signs of bleeding in the brain or stomach. Before starting Fragmin 5000IU, inform your healthcare provider about any pre-existing conditions such as high blood pressure, diabetes, or recent strokes, as well as any ongoing medications to ensure safe usage.

Patients with certain conditions like stomach ulcers, kidney or liver problems, high blood pressure, or bleeding disorders should exercise caution while using Fragmin 5000IU Injection. It is crucial not to discontinue the medication abruptly without consulting your doctor, as this could increase the risk of cardiovascular complications. Additionally, pregnant or breastfeeding women should seek advice from a healthcare professional before starting Fragmin 5000IU Injection. Extra care should be taken to avoid activities that could lead to injuries or bleeding while on this medication.


Benefits

Fragmin 5000IU Injection is a medication that offers several benefits in the treatment and prevention of blood clots. By preventing new blood clots from forming and stopping existing clots from enlarging, Fragmin promotes smooth blood flow throughout the body. This action is crucial in reducing the potential damage caused by blood clots in vital organs such as the lungs, brain, heart, and other blood vessels. For individuals at risk of conditions like pulmonary embolism, stroke, heart attack, or thrombosis, Fragmin can be highly beneficial in minimizing these risks.

One key advantage of Fragmin is its ability to prevent blood clots from growing larger, facilitating the body's natural process of clot dissolution over time. Additionally, Fragmin can help reduce the likelihood of clot fragments breaking off and traveling to other areas of the body, which could lead to further health complications. As a member of the anticoagulant drug class, Fragmin contains Dalteparin, which acts by inhibiting clotting factor Xa and thrombin, essential proteins involved in the blood clotting process. By blocking these substances, Fragmin hinders the conversion of fibrinogen to fibrin, thereby impeding the formation of blood clots.

Specifically, Fragmin is used to prevent clot formation in conditions such as deep vein thrombosis, pulmonary embolism, stroke, irregular heart rhythm (atrial fibrillation), acute coronary syndrome, and risks associated with knee or hip replacement surgeries and abdominal procedures. Its mechanism of action not only mitigates current clot issues but also serves as a preventive measure against future clot formation in individuals at high risk. Overall, Fragmin 5000IU Injection plays a vital role in maintaining cardiovascular health and reducing the incidence of life-threatening clot-related complications.


How to use the Fragmin 5000IU Injection

To use Fragmin 5000IU Injection, it is important to follow the guidance of your doctor or nurse. Do not attempt to self-administer this medicine. A healthcare professional will administer the 0.2 ml injection under your skin as a subcutaneous injection. It is crucial to inform your doctor if you have kidney or liver issues before taking Fragmin 5000IU Injection 0.2 ml, as the dose may need to be adjusted accordingly. Your doctor will determine the appropriate dose and duration of treatment based on factors such as your age, body weight, and the specific condition being treated. Remember, always rely on healthcare professionals for the correct administration of Fragmin 5000IU Injection to ensure safety and effectiveness.


Uses of Fragmin 5000IU Injection

Fragmin 5000IU Injection is used to treat and prevent blood clots in various situations. It helps in preventing venous thromboembolism and its recurrence, particularly in patients who are at risk. This injection is also beneficial in preventing deep vein thrombosis in patients who are bedridden and prone to developing such clots. In addition, Fragmin 5000IU Injection helps to prevent the formation of blood clots in the tubes of medical equipment used during procedures like haemodialysis or hemofiltration. Furthermore, it is utilized in the treatment of solid tumors in patients with low platelet count, where the risk of clot formation is higher. Moreover, Fragmin 5000IU Injection is also effective in treating unstable coronary artery disease, providing essential management for this condition.


What conditions Fragmin 5000IU Injection treats?

"Fragmin 5000IU Injection is used for treating conditions related to blood clots. Blood clots are formed to stop bleeding from tissue injury, but if they form abnormally in blood vessels, they can block essential organs like the brain, heart, or lungs. Deep vein thrombosis (blood clots in legs) and pulmonary embolism (blood clots in the lung) are common conditions where blood clots can cause harm. Symptoms can include leg pain or swelling in the case of deep vein thrombosis and chest pain, cough, and shortness of breath in pulmonary embolism. Blood clots can also lead to severe conditions like stroke and heart attack."


Should you consult a doctor?

It is important to seek medical advice before using Fragmin 5000IU Injection if you have a history of specific health conditions, such as active stomach or small intestinal ulcer, brain hemorrhage, or heparin-induced thrombocytopenia. Additionally, individuals with conditions that increase the risk of bleeding, like hemophilia or liver failure, should consult a doctor before using this medication. Seek immediate medical attention if you have experienced a stroke within the past three months, have fluid mixed with blood around your heart and lungs, or have undergone recent spinal, head, eye, or ear surgery.

Before starting treatment with Fragmin 5000IU Injection, inform your healthcare provider if you have eye disease related to blood pressure or diabetes, suspect a latex allergy, have abnormal levels of potassium or blood pH, recently had surgery or trauma, have a brain tumor, low blood platelet count, or smoke tobacco. Promptly consult a doctor to discuss your medical history and ensure the safe use of Fragmin 5000IU Injection.


Side effects of Fragmin 5000IU Injection

When using Fragmin 5000IU Injection, some side effects may occur. Most side effects are mild and tend to go away as your body gets used to the medication. These include bruising, increased liver enzymes, injection site hematoma, hemorrhagic complications, injection site bruising, nosebleeds, bleeding, and thrombocytopenia (low platelet count). You may also experience haematoma, pain and irritation at the injection site, easy bruising, or temporary muscle weakness. In some cases, there may be red skin rash, itchiness, allergic reactions, or osteoporosis, which can make bones more prone to breaking. Other side effects may include a reversible decrease in platelet count leading to increased bruising, bleeding at various sites, or elevated levels of certain substances produced by the liver. Additionally, you might notice pain, reactions, or hematoma at the injection site, an immune system issue causing a severe decrease in platelets, alopecia (hair loss), or painful skin lesions. It is crucial to stop using the injection and contact your doctor immediately if you experience a severe allergic reaction such as difficulty in breathing or swelling of the lips, mouth, throat, or eyes. If any of these side effects persist or you have concerns, consult your doctor for guidance.


Safety advice

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liver

When using Fragmin 5000IU Injection, caution is advised for patients with severe liver disease. It may be necessary to adjust the dose of Fragmin 5000IU Injection in such cases. It is important to consult with your doctor regarding the use of this medication if you have severe liver disease.

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kidney

Caution should be taken when using Fragmin 5000IU Injection in patients with severe kidney disease. Dose adjustment may be required. Please seek advice from your doctor.

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alcohol

Avoid consuming alcohol while using Fragmin 5000IU Injection as it is not safe to mix the two.

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driving

Fragmin 5000IU Injection generally does not impact your driving ability.

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pregnancy

Fragmin 5000IU Injection is believed to be safe in pregnancy based on animal studies with minimal harm to the baby, but human data is limited.

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breastfeeding

Fragmin 5000IU Injection is likely safe during breastfeeding. Limited data shows minimal risk to the baby as only small amounts transfer to breast milk, posing no expected harm to the baby.


Age above 75(Geriatrics)

Fragmin 5000IU Injection should be used with caution in elderly patients (65 years or older). Consult your doctor for advice.

Age below 6 months(Pediatrics)

Your doctor will prescribe the right dose of Fragmin 5000IU Injection for your child depending on their age, body weight and disease condition.

Consumption warning before consuming Fragmin 5000IU Injection

Before using Fragmin 5000IU Injection 0.2 ml, inform your doctor if you have any allergies to this medication or other drugs. If you are pregnant, breastfeeding, or if the injection is for a child, consult a doctor first. Avoid using the multi-dose form in newborns as it contains benzyl alcohol which can harm them. Older adults over 65 should use Fragmin 5000IU Injection 0.2 ml carefully due to a higher risk of bleeding. Inform your doctor if you have diabetes, high blood pressure, or any bleeding disorders before taking this injection. Do not stop the dosage abruptly without consulting your doctor, as it may lead to serious complications. Prior to any surgery, let your healthcare provider know if you are on Fragmin 5000IU Injection 0.2 ml. Be cautious about potential risks of spinal cord blood clotting if undergoing spinal anesthesia. Avoid alcohol consumption to reduce the risk of stomach bleeding, and take extra care when brushing teeth or shaving to prevent bleeding.


Disease interactions

Before using Fragmin 5000IU Injection 0.2 ml, inform your doctor if you have certain medical conditions. These include haemophilia, diabetes, high blood pressure, congestive heart failure, blood cell disorder (low platelets or low red blood cells), bleeding in the stomach or intestines, history of stroke, kidney or liver issues, or stomach ulcers. It is essential to disclose these conditions to your healthcare provider to ensure safe and effective use of Fragmin 5000IU Injection.


What if you forgot to take Fragmin 5000IU Injection?

If you forget to take a dose of Fragmin 5000IU Injection, it is important to seek advice from your doctor. It is crucial to consult with your healthcare provider in such situations to determine the best course of action. Remember that missing a dose may have an impact on your treatment, so do not hesitate to reach out to your doctor for guidance.


What happens if you take overdose of Fragmin 5000IU Injection?

Overdose with Fragmin 5000IU Injection is uncommon since healthcare professionals like doctors or nurses administer the injection in a hospital setting. These trained individuals carefully monitor the dosage to prevent such occurrences. In the rare event that you do experience any unusual symptoms, it is important to promptly consult your doctor or nurse for assessment and appropriate management. Your healthcare provider can address any concerns and provide necessary guidance if you have any worries about the possibility of an overdose.


Related lab tests

When using Fragmin 5000IU Injection, your doctor may order certain lab tests to monitor your health and response to treatment. These tests can provide valuable information about how well the medication is working and if there are any side effects. Some important lab tests that may be related to Fragmin 5000IU Injection include D-dimer testing. This blood test can help in detecting blood clots by measuring a substance called D-dimer in the blood. Additionally, your doctor may recommend a Computed Tomographic Pulmonary Angiography (CTPA) to check for any blood clots in the lungs. Another test that might be considered is a Ventilation-Perfusion Scan, which is used to evaluate the blood flow and air flow in the lungs. Magnetic Resonance Imaging (MRI) may also be utilized to get detailed pictures of the blood vessels and tissues in the body. These lab tests are essential for monitoring your health and ensuring the effectiveness of Fragmin 5000IU Injection.


Additional Information

Habit FormingNo
Chemical ClassLow molecular weight heparin (LMWH)
Therapeutic ClassBLOOD RELATED
Action ClassLow molecular weight Heparin (LMWH)

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Disclaimer

The information provided on this website is to the best of our abilities to ensure it is accurate, reliable, and reviewed by a team of professionals. It should not be used to diagnose, prevent, or cure any health problem. The information presented here is not intended to create a doctor-patient relationship or replace a registered medical practitioner's advice, diagnosis, or treatment. The absence or provision of any information or warning regarding any medicine should not be assumed as an implied or explicit assurance of safety or efficacy. We highly recommend consulting your registered medical practitioner for all queries or doubts related to your medical condition. Do not ignore professional medical advice or delay seeking it based on the content encountered on our website. We intend to support, not replace, the doctor-patient relationship.

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Dr. Mansi Chaudhari

MBBS - General Medicine

Last update on 11-Feb-2025