Folitrax 15 Injection

By Folitrax

Rx

1ml Injection in a Ampoule

Composition icon

Composition

Methotrexate(15mg/ml)

Manufacturer - Ipca Laboratories Ltd icon

Manufacturer - Ipca Laboratories Ltd

142 AB, Kandivli Industrial Estate, Kandivli (West), Mumbai - 400 067, Maharashtra

Expires on or after icon

Expires on or after

April, 2026

About Folitrax 15 Injection

Folitrax 15 Injection is a medication used to treat various conditions such as rheumatoid arthritis, psoriasis, certain cancers, and Crohn's disease. When used for rheumatoid arthritis, it helps in preventing further damage to the joints. This injection is given under the supervision of a healthcare professional and should never be self-administered. It can be used alone or in combination with other medications, as determined by your doctor based on your specific condition. The dosage and frequency of administration will be decided by your healthcare provider and may need adjustment over time.

It is crucial to follow your doctor's instructions precisely when taking Folitrax 15 Injection to avoid serious side effects. It may take some time for the medication to show its full benefits, so it is important not to stop taking it without consulting your doctor. Alcohol consumption should be avoided as it can increase the risk of liver damage.

Some common side effects of Folitrax 15 Injection include abdominal pain, indigestion, loss of appetite, nausea, vomiting, tiredness, hair loss, and low blood platelets. Your doctor may recommend taking folic acid to help alleviate some of these side effects. If any side effects persist or worsen, it is important to inform your doctor. This medication is potent and can lead to severe side effects in some individuals, affecting their ability to fight infections and potentially causing issues with blood, liver, or kidneys. Regular blood tests will be conducted by your doctor to monitor for any of these possible complications.

Before starting Folitrax 15 Injection, make sure to inform your doctor if you are pregnant, have existing stomach, liver, or kidney problems, or are taking any other medications, especially those for treating infections. Due to the potential interactions with various medicines, it is important to disclose all medications you are currently using to your healthcare team. This medication should not be used during pregnancy or while breastfeeding, as it can be harmful to the baby. Extra precautions should be taken to avoid pregnancy for a few months after completing the treatment with Folitrax 15 Injection. Your doctor may conduct several tests before and during the treatment to monitor your health status and adjust the dosage as necessary.


Benefits

Folitrax 15 Injection offers several benefits for individuals with specific health conditions. In the treatment of rheumatoid arthritis, Folitrax 15 Injection is classified under antimetabolites and is used for severe cases of rheumatoid arthritis when other treatments have been unsuccessful. It is not typically the first treatment option. This medication functions by reducing the body's immune system, which helps to decrease swelling, alleviate pain, reduce stiffness, and enhance overall joint function. To experience the maximum benefits, it is important to follow the prescribed dosage and duration exactly as instructed by your healthcare provider. Consistent and correct usage is essential as it may take several months for the medication to reach its full effectiveness.

Similarly, in the treatment of psoriasis, Folitrax 15 Injection, belonging to the antimetabolites group, can be utilized for severe psoriasis cases where other treatments have not yielded positive results. Psoriasis is a skin condition characterized by rapid growth of skin cells, which is targeted by this potent medication. Due to its potency and toxicity, it is crucial to have a detailed discussion with your doctor about the risks and benefits associated with the treatment. Just like in rheumatoid arthritis treatment, adherence to the prescribed dosage and duration is vital to derive the maximum benefit from Folitrax 15 Injection. It is advisable to avoid consuming alcohol during the course of this treatment and to maintain proper hydration levels by drinking an ample amount of water.

In conclusion, Folitrax 15 Injection offers relief and improvement for individuals with severe rheumatoid arthritis and psoriasis by effectively addressing the underlying causes of these conditions. Adhering to prescribed guidelines and closely monitoring its usage can lead to a significant reduction in symptoms and enhancement in overall well-being.


How to use the Folitrax 15 Injection

When it comes to using Folitrax 15 Injection, it is important to remember that only a doctor or nurse should give you this medicine. It is not recommended to try and administer it yourself. The injection will be given into a muscle (intramuscularly) by a healthcare professional. Your doctor will determine the right dose and how long you should use Folitrax based on factors like your age, weight, and the condition being treated. So, trust your healthcare provider to handle the administration of Folitrax 15 Injection for your safety and well-being.


Uses of Folitrax 15 Injection

The 'Folitrax 15 Injection' is used for the treatment of various conditions such as rheumatoid arthritis, psoriasis, cancer, and Crohn’s disease. It is specifically effective in treating active rheumatoid arthritis in adults, severe arthritis of unknown origin (idiopathic and juvenile) that does not respond to regular pain medications, as well as psoriasis, Crohn’s disease, polyarthritic forms, and certain types of cancer including acute lymphocytic lymphoma and meningeal leukemia. These types of cancer can affect white blood cells in various parts of the body such as the ovary, breast, cervix, lungs, bones, and bladder. Folitrax 15 Injection plays a crucial role in managing these conditions and providing relief to patients suffering from these illnesses.


What conditions Folitrax 15 Injection treats?

Folitrax 15 Injection is used to treat rheumatoid arthritis by preventing further joint damage. It is also effective in treating severe psoriasis, certain cancers, and Crohn's disease. The medicine reduces the body's immune response, leading to decreased swelling, pain relief, and improved function. Follow your doctor's instructions carefully on dosage and duration of treatment to maximize benefits. Side effects may include abdominal pain, indigestion, fatigue, and hair loss. Notify your doctor if side effects persist or worsen. Regular blood tests are necessary to monitor potential complications, including liver and kidney issues.


Should you consult a doctor?

If you have any blood disorders, impaired immune system, severe infections like tuberculosis or HIV, ulcers in the gastro-intestinal tract, bone marrow suppression, certain immunodeficiency syndromes, or upcoming surgery requiring anesthesia, it is important to avoid using FOLITRAX 15MG INJECTION. In case of ulcerative colitis with bowel bleeding, malnutrition, receiving live vaccines, or being malnourished, consult your doctor before starting this medication. Inform your healthcare provider if you have diabetes, are overweight, have a tooth infection, experience abnormal bleeding or bruising, folate deficiency, or are undergoing radiotherapy. Always seek medical advice before beginning FOLITRAX 15MG INJECTION to ensure safe and effective treatment.


Side effects of Folitrax 15 Injection

Side effects of Folitrax 15 Injection can vary in severity and impact. Some common side effects include abdominal pain, indigestion, loss of appetite, nausea, vomiting, tiredness, mouth sores, low blood platelets, and hair loss. In addition, individuals may also experience confusion, depression, fits, inflammation of blood vessels, liver disorders, and diabetes. Other possible side effects include increased sensitivity to light, brown skin discoloration, hair loss, and joint or muscle pain. More serious side effects may include complications such as porous bones (osteoporosis), painful urination, severe allergic reactions, and development of inflammation and ulcers in the vagina. Patients should immediately consult a doctor if they experience severe symptoms like sudden bleeding from the lungs, unusual bruising or bleeding, severe skin peeling or blisters, presence of ulcers in the mouth, or yellowing of the skin and eyes. It is important to seek medical attention promptly for any concerning side effects to ensure proper management and care.


Safety advice

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liver

When considering the use of Folitrax 15 Injection, it's important to be cautious if you have liver disease. Patients with liver issues may require dose adjustment, so consulting your doctor beforehand is crucial. Note that the use of Folitrax 15 Injection is not advised for individuals with severe liver disease. It's vital to discuss your liver condition with your healthcare provider to ensure safe and appropriate use of this medication.

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kidney

Folitrax 15 Injection needs caution in kidney disease. Dosage adjustment may be necessary. Regular kidney function tests are recommended while on this medication.

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alcohol

When taking Folitrax 15 Injection, caution is recommended when drinking alcohol. It is advisable to consult your doctor regarding alcohol consumption with this medication.

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driving

Avoid driving if Folitrax 15 Injection causes drowsiness, dizziness, or vision issues. Your alertness might decrease.

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pregnancy

Folitrax 15 Injection is not safe to use during pregnancy. Studies indicate harmful effects to the developing baby in both pregnant women and animals. It is important to consult your doctor before using this medication during pregnancy.

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breastfeeding

Folitrax 15 Injection is considered unsafe during breastfeeding due to potential toxicity to the baby.


Age above 75(Geriatrics)

FOLITRAX 15MG INJECTION is recommended to be administered with caution and in a lower dosage to elders due to diminished function of the liver and kidneys and reduced folate levels in the blood in old age. Consult the doctor before receiving FOLITRAX 15MG INJECTION.

Age below 6 months(Pediatrics)

FOLITRAX 15MG INJECTION is not recommended for children below the age of 3 years due to a lack of safety data. If needed, your doctor will administer the right dose depending on your child’s age, body weight, and disease condition. Consult the doctor before receiving FOLITRAX 15MG INJECTION.

Consumption warning before consuming Folitrax 15 Injection

Before consuming Folitrax 15 Injection, it's important to know that this medication is used to treat conditions like rheumatoid arthritis, psoriasis, various cancers, and Crohn's disease. It should only be given under the supervision of a healthcare professional and must not be self-administered. Your doctor will determine the appropriate dosage and frequency of administration based on your specific condition, which may change over time. It is crucial to follow your doctor's instructions carefully to avoid serious side effects.

Common side effects of Folitrax 15 Injection include abdominal pain, indigestion, nausea, fatigue, hair loss, and decreased blood platelets. Your doctor may recommend taking folic acid to help manage some of these side effects. If you experience persistent or worsening side effects, inform your doctor immediately. This medication can weaken your immune system and affect your liver, blood, or kidneys, so regular blood tests are necessary.

Before starting treatment, inform your doctor about any existing medical conditions, pregnancy, medications you are taking, and potential pregnancy plans. Folitrax 15 Injection is not advised during pregnancy or breastfeeding as it could harm the baby. Both partners should avoid conception for several months after treatment cessation. Your doctor may conduct various tests before and during treatment to monitor your health closely.


What happens if you take overdose of Folitrax 15 Injection?

'Folitrax 15 Injection' is typically administered under the supervision of a doctor or nurse in a hospital setting, minimizing the risk of an overdose. However, in the rare event of an overdose, it is essential to seek immediate medical attention. Symptoms of a potential overdose may include increased bruising or bleeding, nausea, vomiting, weakness, mouth sores, dark or bloody stools, coughing up blood resembling coffee grounds, or reduced urine output. If you notice any of these symptoms, contact your healthcare provider promptly for evaluation and appropriate management.


Related lab tests

For patients using Folitrax 15 Injection, doctors may recommend certain lab tests to monitor their health and the effects of the medication. These tests can provide valuable information about the patient's condition. Some related lab tests include:

1. Anti Saccharomyces Cerevisiae (ASCA), IgA: This test detects the presence of specific antibodies that may be associated with inflammatory bowel diseases, such as Crohn's disease.

2. Anti Saccharomyces Cerevisiae (ASCA), IgG: Similar to the IgA test, this test looks for a different type of antibody that can help in the diagnosis of inflammatory bowel diseases.

3. Rheumatoid Factor - Agglutination: This test measures the level of rheumatoid factor in the blood, which is often elevated in patients with autoimmune conditions like rheumatoid arthritis.

4. Rheumatoid Factor - Turbidometry: Another method to measure rheumatoid factor levels, providing additional information for the diagnosis and monitoring of rheumatoid arthritis.

5. Rheumatoid Factor IgG Antibody: This test specifically looks for IgG antibodies related to rheumatoid factor, which can aid in diagnosing and managing conditions like rheumatoid arthritis.

In addition to these specific tests, general tests such as Complete Blood Count (CBC)/ Hemogram, Liver Function Test (LFT), and Kidney Function Test (KFT) may also be recommended to assess overall health and monitor any potential side effects of Folitrax 15 Injection. These tests can help healthcare providers ensure the patient's safety and adjust treatment if necessary.


Additional Information

Habit FormingNo
Chemical ClassGlutamic Acid Derivatives
Therapeutic ClassANTI NEOPLASTICS
Action ClassAntimetabolite- Methotrexate

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Disclaimer

The information provided on this website is to the best of our abilities to ensure it is accurate, reliable, and reviewed by a team of professionals. It should not be used to diagnose, prevent, or cure any health problem. The information presented here is not intended to create a doctor-patient relationship or replace a registered medical practitioner's advice, diagnosis, or treatment. The absence or provision of any information or warning regarding any medicine should not be assumed as an implied or explicit assurance of safety or efficacy. We highly recommend consulting your registered medical practitioner for all queries or doubts related to your medical condition. Do not ignore professional medical advice or delay seeking it based on the content encountered on our website. We intend to support, not replace, the doctor-patient relationship.

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Dr. Archana Prabhakar

MBBS, M.Med (Family Medicine)

Last update on 11-Feb-2025