Epotrend 4000 Injection
By Epotrend
Rx
1ml Injection in a Prefilled syringe

Composition
Recombinant Human Erythropoietin Alfa(4000IU)

Manufacturer - Anthem Biopharma
No 49, Canara Bank Road, Bommasandra Industrial Area, Phase 1, Hosur Road, Bangalore 560 099, Karnataka, India.

Expires on or after
July, 2025
About Epotrend 4000 Injection
Epotrend 4000 Injection is a medication designed to assist the bone marrow in generating more red blood cells. This treatment is primarily used to address a specific type of anemia triggered by kidney disease. It is also beneficial in managing anemia resulting from cancer chemotherapy and certain medications used to combat HIV. The administration of Epotrend 4000 Injection is typically done through injection, either underneath the skin or directly into a vein, as determined by your healthcare provider. The dosage required depends on individual body weight and the underlying cause of the anemia. For enhanced efficacy, it is recommended to complement the treatment with iron supplements before and during the therapy. Proper storage of Epotrend 4000 Injection involves refrigeration, but it should be used at room temperature.
Potential side effects associated with this medication may include common symptoms like nausea, vomiting, fever, and elevated blood pressure. Some individuals might also experience flu-like manifestations such as headaches, fatigue, dizziness, and general body aches at the initial stages of treatment. Should these side effects persist, consulting your doctor is advisable for guidance on preventive measures or symptom management. It is vital to promptly notify your healthcare provider if you encounter severe side effects like seizures, as Epotrend 4000 Injection could potentially lead to serious blood clots that necessitate urgent medical attention.
Prior to commencing Epotrend 4000 Injection, disclose to your doctor if you have uncontrolled hypertension, heart conditions, or gout. It is important to inform your healthcare provider about any other medications you are currently taking, as they could interact with this treatment. Regular monitoring of blood pressure is essential throughout the therapy, either by yourself or under the supervision of a medical professional. Furthermore, additional routine tests may be required to ensure that the medication is not causing adverse effects. If you are pregnant, planning for pregnancy, or breastfeeding, informing your doctor is imperative, as the impact of this medication on an unborn baby is not conclusively known. It is strongly advised to seek medical guidance before using Epotrend 4000 Injection in these situations.
Benefits
Epotrend 4000 Injection offers significant benefits for patients dealing with anemia caused by chronic kidney disease and cancer chemotherapy. In the context of chronic kidney disease, this man-made protein supports the bone marrow in generating more red blood cells. By addressing the root cause of anemia, which is the insufficient red blood cells to transport oxygen in the body, Epotrend 4000 Injection plays a crucial role in managing fatigue and weakness commonly associated with this condition. Patients undergoing dialysis can particularly benefit from this treatment post-procedure, as it helps in replenishing red blood cell levels effectively.
Similarly, in the case of anemia induced by cancer chemotherapy, Epotrend 4000 Injection's function revolves around stimulating the bone marrow to increase red blood cell production. During chemotherapy, natural levels of this essential protein may decrease, impacting the body's ability to maintain adequate red blood cell counts. By receiving this injection, patients may experience a reduction in the need for blood transfusions, which are often necessary to manage severe anemia. Additionally, supplementing the treatment with iron supplements can further enhance its effectiveness.
Overall, Epotrend 4000 Injection presents as a valuable therapeutic option for individuals facing anemia in the context of chronic kidney disease and cancer chemotherapy. By empowering the body to generate more red blood cells, this medication contributes to improving oxygen circulation, reducing symptoms of weakness and tiredness, and ultimately enhancing the quality of life for patients undergoing these challenging medical conditions.
How to use the Epotrend 4000 Injection
To use Epotrend 4000 Injection, it is important to have a healthcare professional, such as a doctor or nurse, administer the medicine to you. This means you should not try to inject the medicine yourself. It is crucial to follow their instructions carefully and not attempt to self-administer the injection. By having a healthcare professional administer Epotrend 4000 Injection, you can ensure that it is administered correctly and safely. By following this guidance, you can help maximize the benefits of the medicine for your health condition. Always consult with your healthcare provider if you have any questions or concerns about the proper use of Epotrend 4000 Injection.
Uses of Epotrend 4000 Injection
The Epotrend 4000 Injection is used for treating anemia resulting from chronic kidney disease and anemia caused by cancer chemotherapy. This injectable medication helps boost red blood cell production in the body, addressing the low red blood cell count common in these conditions. By increasing red blood cells, Epotrend 4000 Injection can alleviate symptoms such as fatigue, weakness, and shortness of breath, improving the quality of life for patients undergoing treatment for these specific types of anemia.
What conditions Epotrend 4000 Injection treats?
Epotrend 4000 Injection is used to treat anemia caused by chronic kidney disease in adults and children on dialysis. Anemia is a condition where the body lacks enough red blood cells to carry oxygen, leading to weakness and tiredness. Additionally, it is used for anemia caused by cancer chemotherapy, stimulating the bone marrow to produce more red blood cells. Iron supplements may enhance treatment effectiveness. Common side effects include nausea, vomiting, fever, and increased blood pressure, with rare occurrences of serious blood clots. Patients with specific conditions should discuss with a doctor before using this medicine. Regular blood pressure checks and medical tests may be required during treatment.
Should you consult a doctor?
If you experience any serious side effects such as seizures, it is important to seek medical attention promptly. Additionally, if you encounter persistent side effects like nausea, vomiting, fever, rash, joint pain, headache, dizziness, or muscle spasms, it is advisable to consult your doctor. Any signs of vascular occlusion, injection site irritation, or stomatitis should also prompt you to seek medical advice.
Moreover, if you have uncontrolled high blood pressure, heart disease, or gout, it is crucial to discuss this with your doctor before starting Epotrend 4000 Injection. Regular monitoring of your blood pressure during treatment is essential, along with other medical tests to ensure the medication is not causing any harmful effects. If you are pregnant, planning to conceive, or breastfeeding, informing your doctor is necessary to assess potential risks. Remember, it is always best to consult your healthcare provider if you have any concerns or questions regarding the treatment.
Side effects of Epotrend 4000 Injection
When taking Epotrend 4000 Injection, there are potential side effects to be aware of. These side effects are usually mild and temporary as your body gets used to the medication. However, it's important to consult your doctor if any of the following side effects persist or if you have concerns about them:
- High blood pressure
- Nausea
- Vomiting
- Fever
- Rash
- Joint pain
- Headache
- Insomnia (difficulty sleeping)
- Chills
- Cough
- Bone pain
- Muscle spasm
- Dizziness
- Vascular occlusion
- Injection site irritation
- Stomatitis (Inflammation of the mouth)
- Weight loss
- Decreased white blood cell count (lymphocytes)
- Increased glucose levels in blood
- Blood clot in the blood vessels
If you experience any of these side effects while taking Epotrend 4000 Injection, it's essential to seek advice from your healthcare provider for appropriate management and guidance.
Safety advice

liver
When using Epotrend 4000 Injection, it is important to be cautious if you have liver disease. Patients with liver issues may require a dose adjustment of Epotrend 4000 Injection. It is recommended to consult your doctor for proper guidance on the use of this injection when dealing with liver-related concerns.

kidney
Epotrend 4000 Injection is safe for patients with kidney disease. No dosage adjustment is needed. Regular kidney function tests are recommended during treatment.

alcohol
It is not known if it is safe to drink alcohol while using Epotrend 4000 Injection. Please ask your doctor.

driving
When using Epotrend 4000 Injection, be cautious while driving as it may cause side effects that can impact your ability to drive safely. Be aware of any potential impairments to focus and reaction time while on this medication.

pregnancy
Epotrend 4000 Injection may not be safe to use during pregnancy. Limited human studies suggest potential harm to the baby. Your doctor will assess risks and benefits before prescribing. Consult your doctor for more information.

breastfeeding
Epotrend 4000 Injection is likely safe while breastfeeding. Studies indicate minimal risk to the baby based on limited human data.
Consumption warning before consuming Epotrend 4000 Injection
Before using Epotrend 4000 Injection to treat anemia caused by kidney disease, cancer chemotherapy, or HIV medications, it is important to be aware of the following precautions. This medication is administered through injection under the skin or into a vein, with the dosage determined based on body weight and the underlying cause of anemia. It is crucial for the injections to be given by a healthcare professional. While iron supplements can enhance the effectiveness of this treatment, it is essential to store Epotrend 4000 Injection in the fridge but administer it at room temperature.
Common side effects may include nausea, vomiting, fever, and increased blood pressure, along with flu-like symptoms such as headache and tiredness. Contact your doctor immediately if you experience severe side effects like seizures or blood clots. Prior to starting this treatment, inform your doctor about any existing conditions like uncontrolled high blood pressure or heart disease. Regular monitoring of blood pressure and medical tests may be necessary during the course of treatment to ensure safety. If you are pregnant, planning to conceive, or breastfeeding, consult your doctor beforehand as the impact on an unborn baby is not known.
What if you forgot to take Epotrend 4000 Injection?
If you forget to take a dose of Epotrend 4000 Injection, it is important to speak with your doctor. Consulting your healthcare provider for guidance on the missed dose is crucial to ensure proper management of your condition. Seeking advice from your doctor will help determine the best course of action to take in case of a missed dose of Epotrend 4000 Injection. Remember, your doctor is there to support you in maintaining your treatment plan, so do not hesitate to reach out if you have any concerns about missed doses.
Related lab tests
When you are taking Epotrend 4000 Injection, your healthcare provider may recommend certain lab tests to monitor your health and see how the treatment is working. Two important lab tests that are commonly related to this injection are the Complete Blood Count (CBC) and Peripheral Smear Examination.
The Complete Blood Count (CBC) test gives valuable information about the different types of cells in your blood, including red blood cells, white blood cells, and platelets. This test can help track any changes in your blood cell levels that may occur while using Epotrend 4000 Injection.
Another important test is the Peripheral Smear Examination, which involves looking at a small sample of your blood under a microscope to examine the size, shape, and appearance of your blood cells. This test can provide additional information about your blood cells and help healthcare providers detect any abnormalities.
Both these lab tests can help healthcare providers monitor your overall health and assess how your body is responding to Epotrend 4000 Injection. It is important to follow your healthcare provider's recommendations for these lab tests to ensure the safe and effective use of this injection.
Related Lab Tests:
1. Complete Blood Count (CBC)
2. Peripheral Smear Examination
Additional Information
Habit Forming | No |
Chemical Class | Amino Acids, Peptides, and Analogues |
Therapeutic Class | BLOOD RELATED |
Action Class | Erythropoiesis-stimulating agent (ESA) |
FAQs
Disclaimer
The information provided on this website is to the best of our abilities to ensure it is accurate, reliable, and reviewed by a team of professionals. It should not be used to diagnose, prevent, or cure any health problem. The information presented here is not intended to create a doctor-patient relationship or replace a registered medical practitioner's advice, diagnosis, or treatment. The absence or provision of any information or warning regarding any medicine should not be assumed as an implied or explicit assurance of safety or efficacy. We highly recommend consulting your registered medical practitioner for all queries or doubts related to your medical condition. Do not ignore professional medical advice or delay seeking it based on the content encountered on our website. We intend to support, not replace, the doctor-patient relationship.
₹1600
Inclusive of all taxes
Content verified by

Dr. Archana Prabhakar
MBBS, M.Med (Family Medicine)
Last update on 11-Feb-2025