Depakote 250 Tablet
By Depakote
Rx
15 Tablet in a Strip

Composition
Divalproex(250mg)

Manufacturer - Sanofi India Ltd
Sanofi House, CTS No.117-B, L&T Business Park, Saki Vihar Road, Powai, Mumbai 400072

Expires on or after
July, 2026
About Depakote 250 Tablet
Depakote 250 Tablet, also known as DEPAKOTE 250MG TABLET or Depakote 250 Tablet 15's, is a medication classified as an anticonvulsant or anti-epileptic drug. This medication is primarily used in the treatment of epilepsy to help prevent and control seizures, also known as fits. Additionally, Depakote 250 Tablet is used to manage the occurrence of migraines and is occasionally prescribed for individuals dealing with bipolar disorder.
The active ingredient in Depakote 250 Tablet is Divalproex sodium, which works to reduce excessive and abnormal nerve activity in the brain. By increasing the levels of a chemical substance called GABA, Depakote 250 Tablet helps block nerve transmissions across the brain, resulting in a calming effect that aids in managing bipolar disorder symptoms. For individuals with epilepsy, the medication helps balance the brain's electrical rhythms to prevent recurrent seizures.
It is essential to follow your doctor's prescribed dose and schedule when taking Depakote 250 Tablet to effectively control your symptoms. While the medication can be taken with or without food, maintaining a consistent daily intake time is crucial for optimal benefits. It typically takes a few weeks for Depakote 250 Tablet to start working, underscoring the importance of regular and prolonged use as advised by your healthcare provider.
Common side effects associated with Depakote 250 Tablet include headache, blurred vision, nausea, vomiting, dizziness, tiredness, and unsteadiness. Although most of these side effects are mild and temporary, it is important to consult your doctor if they persist or become bothersome. Notably, a skin rash, redness, or signs of decreased body temperature should prompt immediate medical attention.
Individuals considering Depakote 250 Tablet should disclose their medical history, especially if they have a history of heart problems, kidney or liver diseases, depression, or suicidal thoughts. Informing your doctor about any medications you are currently taking is crucial to avoid potential interactions and ensure the safe use of Depakote 250 Tablet. Pregnant individuals or those planning pregnancy should seek medical advice before starting or discontinuing the medication, as it can pose risks to fetal development.
In conclusion, Depakote 250 Tablet is a valuable medication for managing epilepsy, bipolar disorder, and migraines. Adhering to your doctor's instructions, monitoring for side effects, and communicating openly about your health status are key aspects of ensuring safe and effective treatment with Depakote 250 Tablet.
Benefits
Depakote 250 Tablet offers several benefits in treating various medical conditions. Firstly, for individuals suffering from epilepsy or seizures, this medication acts as an anticonvulsant, working to lower the nerve impulses that trigger seizures. By managing the frequency of seizures, Depakote 250 Tablet enables individuals to carry out their daily tasks with increased confidence. This medication helps alleviate symptoms like confusion, uncontrollable jerking movements, loss of awareness, and fear or anxiety. It is important to note that Depakote 250 Tablet does not lead to physical or psychological dependence but should be taken regularly as prescribed to be effective. Missing doses can potentially trigger a seizure, so adherence to the prescribed regimen is crucial for optimal results.
Moreover, Depakote 250 Tablet is beneficial in the treatment of bipolar disorder by restoring the balance of nerve activity in the brain. This helps in preventing extreme mood swings and reducing agitation, leading to fewer episodes of low mood. While it may take some time for the medication to show its full effect, it is essential to continue taking it as advised by the healthcare provider. Typically, individuals may need to take Depakote 250 Tablet for at least six months, or possibly longer, to experience its full benefits. Maintaining a healthy lifestyle, including proper diet and regular exercise, can further help in managing symptoms of bipolar disorder.
Additionally, Depakote 250 Tablet has shown efficacy in the prevention of migraines, although the exact mechanism of action is not fully understood. It is believed to influence nerve cell activity in the brain, potentially reducing abnormal or excessive activity associated with migraines. By preventing and decreasing the frequency of headaches, this medication can significantly improve an individual's quality of life, enabling them to engage in daily activities with greater ease.
In conclusion, Depakote 250 Tablet offers valuable benefits in the management of epilepsy, bipolar disorder, and migraine prevention. Adhering to the prescribed dosage and regimen is essential to harness the full therapeutic potential of this medication and achieve the desired outcomes in improving overall well-being and quality of life.
How to use the Depakote 250 Tablet
When using Depakote 250 Tablet, it is essential to follow your doctor's instructions. Take the tablet exactly as directed, in both dosage and duration. Swallow the tablet whole with a glass of water; do not chew, crush, or break it. While you can take Depakote 250 Tablet with or without food, it is preferable to take it at the same time each day to maintain consistency. Your doctor will determine the correct dosage and duration based on factors such as your age, weight, and the specific condition being treated. It is important not to discontinue the use of Depakote 250 Tablet unless advised by your doctor. If you have any questions or concerns about how to use this medication, consult your healthcare provider for clarification and guidance.
Uses of Depakote 250 Tablet
Depakote 250 Tablet is commonly used for treating epilepsy/seizures, bipolar disorder, and for preventing migraines. It helps manage and control mania associated with bipolar disorder. It is effective in treating complex partial seizures in adults and children aged 10 and above, as well as simple and complex absence seizures, sometimes occurring with other types of seizures. Additionally, this medication is used to prevent migraine headaches.
What conditions Depakote 250 Tablet treats?
Depakote 250 Tablet is used to treat epilepsy, helping prevent seizures. It can also be used to prevent migraines and occasionally for bipolar disorder. This medication reduces nerve impulses that cause seizures, improving daily activities. It needs to be taken regularly to be effective; missing doses may trigger a seizure. For bipolar disorder, it restores the balance of nerve activity, reducing extreme mood changes. In migraine prevention, it may alter nerve cell activity in the brain. Side effects are typically mild, but consult your doctor if you experience any concerns.
Should you consult a doctor?
If you experience any of the following conditions, it is important to seek medical advice before taking Depakote 250 Tablet:
- If you have porphyria, urea cycle disorder, or a genetic problem from a mitochondrial disorder like Alpers-Huttenlocher syndrome.
- If you are switching from another medication containing valproate.
- If you have epilepsy, a brain disease, or any condition affecting the brain.
- If you have pancreatic issues, high blood sugar, or are undergoing diabetes testing.
- If you are carnitine palmitoyl transferase type II deficient.
- If you have systemic lupus erythematosus, a rare immune system disease.
- If you have a history of depression, mood disorders, or suicidal thoughts or behavior.
- If you have any other significant medical conditions.
Always consult your doctor to ensure Depakote 250 Tablet is safe and suitable for you based on your individual health circumstances.
Side effects of Depakote 250 Tablet
Depakote 250 Tablet may cause various side effects, some of which are common and may go away as your body gets used to the medication. These include decreased body temperature, dizziness, sleepiness, tremors, tingling or pricking sensations (known as paresthesia), anemia, decreased sodium levels in the blood, liver injury, gastrointestinal disturbances, hypersensitivity, deafness, urinary incontinence, increased body weight, and pain during periods. Other side effects that may occur but require immediate medical attention include nausea, vomiting, diarrhea, changes in appetite, stomach pain, headache, weakness, blurry or double vision, weight gain, hair loss, coordination issues, skin problems like rashes, and more severe conditions such as toxic epidermal necrolysis, erythema multiforme, angioedema, liver problems, pancreatic issues, jerky muscle movements, and decreased platelet or white blood cell counts. Contact your doctor right away if you experience any of these serious side effects while taking Depakote 250 Tablet.
Safety advice

liver
Depakote 250 Tablet may not be safe for individuals with liver disease, and it is advised to avoid using this medication. It is important to consult your doctor for proper guidance regarding the use of Depakote 250 Tablet if you have liver issues.

kidney
It is safe to use Depakote 250 Tablet in patients with kidney disease. No dose adjustment is needed for this medicine in such patients.

alcohol
Depakote 250 Tablet can lead to extreme drowsiness when taken with alcohol. It is important to be cautious when consuming alcohol while on this medication.

driving
When taking Depakote 250 Tablet, be cautious while driving as it may cause side effects that can impact your ability to drive safely.

pregnancy
Depakote 250 Tablet is considered unsafe during pregnancy due to potential risks to the developing baby. It may be prescribed in life-threatening situations only when benefits outweigh risks. Consult your doctor before use.

breastfeeding
Depakote 250 Tablet is considered safe to use during breastfeeding. Research shows the medication is unlikely to pass into breastmilk in harmful amounts, posing minimal risk to the baby.
Age above 75(Geriatrics)
Depakote 250 Tablet should be used with caution in elderly patients as they may experience drowsiness or sleepiness. Consult your doctor before taking it.
Age below 6 months(Pediatrics)
Depakote 250 Tablet is not recommended for use in children (younger than two years) who are at a considerably increased risk of developing liver toxicity. Consult your doctor before taking it.
Consumption warning before consuming Depakote 250 Tablet
Before consuming Depakote 250 Tablet, it is important to note the following information. This medication is primarily used for epilepsy and migraine prevention, and occasionally for bipolar disorder. Your doctor will determine the appropriate dosage and frequency based on your condition. It may take a few weeks to take effect, so consistency is key. Abruptly stopping the medication can worsen your condition and trigger seizures.
Common side effects include headache, nausea, and dizziness. However, if you experience a skin rash or notice redness, consult your doctor immediately. Prolonged use of Depakote 250 Tablet may lead to osteoporosis and increase the risk of bone fractures. In rare cases, it may cause suicidal thoughts. Inform your doctor if you have a history of heart problems, depression, or if you are pregnant.
Avoid alcohol while on this medication as it can intensify side effects and seizure risks. Additionally, inform your doctor about all medications you are taking to prevent interactions. Regular blood tests may be necessary to monitor the effectiveness and safety of the treatment.
What if you forgot to take Depakote 250 Tablet?
If you forget to take a dose of the Depakote 250 Tablet, try to take it as soon as you remember. But if it's close to the time for your next scheduled dose, then it's best to skip the missed dose and resume your normal dosing routine. Avoid taking a double dose to make up for the missed one. It is important to follow the prescribed dosing schedule to ensure the effectiveness of the medication.
What happens if you take overdose of Depakote 250 Tablet?
In case of an overdose of Depakote 250 Tablet, seek immediate medical help from your doctor or the nearest hospital. Symptoms of Depakote 250 Tablet overdose may include nausea, vomiting, headache, blurred vision, dizziness, impaired reflexes, confusion, memory loss, fatigue, weak muscles, seizures, loss of consciousness, changes in behavior, rapid breathing, shortness of breath, or chest pain. If you or someone else has taken too much Depakote 250 Tablet , it is important to get prompt medical attention to address the situation effectively and prevent any further complications.
Related lab tests
Related Lab Tests for Depakote 250 Tablet:
Before starting treatment with Depakote 250 Tablet, your healthcare provider may recommend you undergo certain lab tests to monitor your health and ensure the medication is safe and effective for you. Two common lab tests that may be recommended are Electroencephalogram (EEG) and MRI (magnetic resonance imaging).
1. Electroencephalogram (EEG):
An EEG test measures the electrical activity in your brain. This test can help evaluate brain function and detect any abnormal patterns that may indicate certain neurological conditions or disorders. Your healthcare provider may recommend an EEG before starting Depakote 250 Tablet to establish a baseline brain activity and monitor any changes during treatment.
2. MRI (Magnetic Resonance Imaging):
An MRI is a diagnostic imaging test that uses a magnetic field and radio waves to create detailed images of the organs and tissues inside your body, including the brain. Your healthcare provider may suggest an MRI before or during treatment with Depakote 250 Tablet to assess the structure of the brain and detect any abnormalities that may impact your treatment plan.
These lab tests can provide valuable information to your healthcare provider to ensure the safe and effective use of Depakote 250 Tablet. It is important to follow your healthcare provider's recommendations regarding these lab tests to optimize your treatment outcome.
Additional Information
Habit Forming | No |
Chemical Class | Aliphatic Carboxylic acid Derivatives |
Therapeutic Class | NEURO CNS |
Action Class | Sodium channel modulators (AED) |
FAQs
Disclaimer
The information provided on this website is to the best of our abilities to ensure it is accurate, reliable, and reviewed by a team of professionals. It should not be used to diagnose, prevent, or cure any health problem. The information presented here is not intended to create a doctor-patient relationship or replace a registered medical practitioner's advice, diagnosis, or treatment. The absence or provision of any information or warning regarding any medicine should not be assumed as an implied or explicit assurance of safety or efficacy. We highly recommend consulting your registered medical practitioner for all queries or doubts related to your medical condition. Do not ignore professional medical advice or delay seeking it based on the content encountered on our website. We intend to support, not replace, the doctor-patient relationship.
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Content verified by

Dr. Abdullah Khan
MBBS - General Medicine
Last update on 01-Oct-2024