Defrijet 250 Tablet
By Defrijet
Rx
10 Tablet in a Strip

Composition
Deferasirox(250mg)

Manufacturer - Sun Pharmaceutical Industries Ltd
Plot no 107/108,Namli block , Ranipool, East Sikkim 737135

Expires on or after
April, 2026
About Defrijet 250 Tablet
Defrijet 250 Tablet is a medication used to treat chronic iron overload resulting from regular blood transfusions. This excess iron in the body can potentially cause damage to vital organs. The tablet is designed to help remove the surplus iron and decrease the risk of organ injury. It is advisable to take Defrijet 250 Tablet on an empty stomach, ensuring precise dosage and duration intake at the same time daily to maximize its benefits.
Defrijet 250 Tablet belongs to a group of medications known as iron chelators. It contains an active ingredient called deferasirox, which acts as a trivalent iron selective chelating agent. This component binds to the excess iron in the body and eliminates it through feces, thereby reducing the danger of organ harm. The tablet is available in oral formulations and is prescribed for patients with chronic iron overload due to blood transfusions or non-transfusion-dependent thalassemia.
Common side effects from using Defrijet 250 Tablet may include nausea, headache, constipation, diarrhea, and increased liver enzymes. These side effects, while generally mild, should be reported to your doctor if they persist or worsen. It is crucial to inform your doctor about any existing kidney or liver conditions before starting treatment with Defrijet 250 Tablet. Additionally, disclose all other medications you are currently taking to ensure your safety during treatment.
Defrijet 250 Tablet 10's, another variation of the medication, can be prescribed to patients of different age groups based on their specific medical conditions. It is crucial to adhere strictly to the prescribed dosage and duration recommended by your healthcare provider. Monitoring of kidney and liver function may be necessary during treatment. Pregnant and breastfeeding women are typically advised against using Defrijet 250 Tablet unless deemed necessary by a medical professional. Children under 2 years of age are also not recommended for treatment with this medication.
In summary, Defrijet 250 Tablet and Defrijet 250mg Tablet contain deferasirox and serve to manage chronic iron overload caused by various conditions such as beta thalassemia major and non-transfusion-dependent thalassemia syndromes. Adhering to medical guidance and reporting any persistent side effects are essential for safe and effective treatment.
Benefits
Defrijet 250 Tablet is a beneficial medication used in the treatment of iron overload, a condition characterized by an excess of iron in the body. When there is too much iron present, it can lead to severe organ damage and increase the risk of serious health conditions such as cancer, irregular heartbeat, and liver cirrhosis. Symptoms associated with iron overload may include high blood sugar levels, skin darkening, abnormal heart rhythm, and arthritis.
By taking Defrijet 250 Tablet as prescribed by your doctor, the excess iron in the body can be effectively reduced to safe levels. The active component in Defrijet 250 Tablet is Deferasirox, a chelating agent that specifically binds to trivalent iron. By binding to the excess iron, Deferasirox helps to eliminate it from the body through stools. This mechanism of action assists in reducing the risk of organ damage and prevents the development of further complications associated with iron overload.
Overall, the benefits of Defrijet 250 Tablet include its ability to decrease excess iron levels in the body, thereby lowering the risk of organ damage and mitigating the potential for serious health issues related to iron overload. It is essential to follow the prescribed dosage and instructions provided by your healthcare provider to achieve the maximum benefit from using Defrijet 250 Tablet. By effectively managing iron overload with this medication, individuals can enhance their overall health and well-being.
How to use the Defrijet 250 Tablet
To properly use Defrijet 250 Tablet, it is important to follow your doctor's instructions. Take the tablet as advised by your physician, usually on an empty stomach. Swallow the tablet whole with a glass of water; do not chew, crush, or break it. The dosage and duration of treatment will be determined by your doctor based on factors such as your age, body weight, and the specific condition being treated. Be sure to adhere to the prescribed dose and duration, even if you start feeling better before completing the course of medication. If you have any questions or concerns about how to use Defrijet 250 Tablet, consult your doctor or pharmacist for further guidance.
Uses of Defrijet 250 Tablet
Defrijet 250 Tablet is used to treat chronic iron overload caused by blood transfusions, known as transfusional hemosiderosis, in patients aged 2 years and older. It can also be used to manage chronic iron overload in patients with non-transfusion-dependent thalassemia (NTDT) who are 10 years of age and older. This medication is specifically designed to help reduce the excess iron levels in the body that can accumulate over time due to these conditions. By targeting the underlying cause of iron overload, Defrijet 250 Tablet plays a crucial role in managing these conditions and improving the overall well-being of patients.
What conditions Defrijet 250 Tablet treats?
Defrijet 250 Tablet is used to treat hemochromatosis, a condition where the body accumulates excess iron. This excess iron storage can lead to serious harm to vital organs such as the heart, liver, and pancreas.
Should you consult a doctor?
If you are considering Defrijet 250 Tablet, it is important to seek medical advice. Contact your doctor if you have conditions such as advanced myelodysplastic syndrome, advanced cancer, poor performance status, or severe thrombocytopenia, as this medication may not be suitable for you. Before starting Defrijet 250 Tablet, inform your doctor if you have low levels of white blood cells, worsening anaemia, pancytopenia, or bone marrow failure. Additionally, let your doctor know if you experience symptoms like blurred vision, decreased hearing, diarrhoea, vomiting, gastrointestinal ulcers, or haemorrhages. Seeking medical advice is crucial to ensure Defrijet 250 Tablet is safe and appropriate for your condition.
Side effects of Defrijet 250 Tablet
Defrijet 250 Tablet may cause various side effects, although not everyone experiences them. Most side effects are temporary and may go away as your body gets used to the medication. Common side effects include nausea, headache, vomiting, rash, abdominal pain, constipation, itching, and increased liver enzymes. In some cases, you may also experience diarrhea, dizziness, fever, sore throat, swelling of the arms or legs, changes in skin color, anxiety, sleep disorders, and fatigue. If you encounter severe allergic reactions such as rash, red skin, blisters, peeling skin, high fever, flu-like symptoms, or difficulty breathing, you should stop taking the tablet immediately and consult your doctor. Other serious side effects requiring immediate medical attention include decreased urine output, signs of liver problems like abdominal pain or jaundice, high ammonia levels leading to changes in brain function, vomiting blood or black stools, severe abdominal pain, heartburn, vision or hearing loss, and pancreatitis. It is important to be aware of these potential side effects and seek medical advice if you experience any of them to ensure your safety and well-being.
Safety advice

liver
Defrijet 250 Tablet needs to be used carefully in individuals with liver disease. It may require a change in dosage, so consulting your doctor is crucial. There is limited data on the use of Defrijet 250 Tablet in patients with liver issues.

kidney
Defrijet 250 Tablet may be unsafe for patients with kidney disease; consult your doctor.

alcohol
Consult your doctor when consuming alcohol with Defrijet 250 Tablet.

driving
When taking Defrijet 250 Tablet, be cautious while driving as it may reduce alertness, impact vision, and cause drowsiness or dizziness. Refrain from driving if experiencing these effects.

pregnancy
Defrijet 250 Tablet could be risky during pregnancy. Animal studies indicate potential harm to the baby. The doctor will consider benefits and risks before prescribing. Kindly consult your doctor before use.

breastfeeding
Defrijet 250 Tablet is likely safe during breastfeeding. Limited data shows no significant risk to the baby.
Age above 75(Geriatrics)
Age below 6 months(Pediatrics)
Consumption warning before consuming Defrijet 250 Tablet
Before taking Defrijet 250 Tablet, do not use it if you have allergies to the tablet itself or its components. This medication is generally not advised for pregnant or breastfeeding women due to uncertain safety profiles. However, your doctor may consider the benefits versus risks when prescribing it. It is not known if Defrijet 250 Tablet affects driving ability, so refrain from driving or using machinery if you experience concentration or reaction issues. Seek medical help if these symptoms persist. Avoid alcohol consumption when taking Defrijet 250 Tablet as it may cause adverse reactions. Close monitoring is essential for elderly and pediatric patients to prevent toxicity.
Disease interactions
Individuals with bone marrow suppression, dermatologic toxicities, hepatic impairment, renal dysfunction, auditory and ocular abnormalities, as well as gastrointestinal complications are advised to seek guidance from a healthcare provider before initiating Defrijet 250 Tablet 30's. This precaution is crucial to ensure the safe and effective use of the medication, as these conditions may interact with the drug and impact its efficacy or safety. Consulting a doctor helps in determining the appropriateness of Defrijet 250 Tablet 30's in the context of these specific health issues and aids in minimizing any potential risks or interactions associated with the treatment.
What if you forgot to take Defrijet 250 Tablet?
If you forget to take your Defrijet 250 Tablet, take it when you remember. But if it's close to your next scheduled dose, just skip the missed one and continue with your usual dosing routine. Avoid taking double the dose to make up for the missed one. Follow your treatment plan consistently to get the most benefit from your medication.
What happens if you take overdose of Defrijet 250 Tablet?
In case of an accidental overdose of Defrijet 250 Tablet, it is crucial to seek medical help promptly. Overdosing on this medication can lead to various symptoms such as nausea, vomiting, abdominal pain, diarrhea, and potential kidney or liver issues. If you suspect an overdose, do not hesitate to consult your doctor or go to the nearest hospital for immediate assistance. It is essential to address an overdose situation without delay to ensure proper medical intervention and management of any potential complications that may arise.
Related lab tests
When taking Defrijet 250 Tablet, it is important to monitor certain lab tests to ensure the medication is working effectively and not causing any harmful effects. Related lab tests that may be recommended while using Defrijet 250 Tablet include Iron Serum, Iron Studies, and Total Iron Binding Capacity tests. These tests help in assessing the levels of iron in the body and monitoring how the medication is affecting iron levels.
In addition to these specific tests related to iron levels, it is also important to consider other tests to ensure overall health and safety. These may include Urine Routine & Microscopy to check for any abnormalities in the urine, Bilirubin Profile to assess liver function, Kidney Function Test (KFT) to evaluate kidney health, and Liver Function Test (LFT) to monitor liver function.
Other related lab tests that may be recommended while taking Defrijet 250 Tablet include tests such as Creatinine, Serum to assess kidney function, Uric Acid, Serum to evaluate uric acid levels, Albumin, Serum to check protein levels, Alkaline Phosphatase, Serum to assess bone and liver health, Bilirubin Direct, Serum to monitor liver health, and Bilirubin Total, Serum to evaluate overall liver function. Regular monitoring of these lab tests can help in ensuring the safety and effectiveness of Defrijet 250 Tablet therapy.
Additional Information
Habit Forming | No |
Chemical Class | Triazole & benzoate derivative |
Therapeutic Class | - |
Action Class | Iron chelating agents |
FAQs
Disclaimer
The information provided on this website is to the best of our abilities to ensure it is accurate, reliable, and reviewed by a team of professionals. It should not be used to diagnose, prevent, or cure any health problem. The information presented here is not intended to create a doctor-patient relationship or replace a registered medical practitioner's advice, diagnosis, or treatment. The absence or provision of any information or warning regarding any medicine should not be assumed as an implied or explicit assurance of safety or efficacy. We highly recommend consulting your registered medical practitioner for all queries or doubts related to your medical condition. Do not ignore professional medical advice or delay seeking it based on the content encountered on our website. We intend to support, not replace, the doctor-patient relationship.
₹241.6
Inclusive of all taxes
Content verified by

Dr. Abdullah Khan
MBBS - General Medicine
Last update on 01-Oct-2024