Darzalex Injection

By Darzalex

Rx

5ml Injection in a Vial

Composition icon

Composition

Daratumumab(100mg)

Manufacturer - Janssen Pharmaceuticals icon

Manufacturer - Janssen Pharmaceuticals

Johnson & Johnson Private Limited., 501 Arena Space, Behind Majas Bus Depot, Off Jogeshwari Vikhroli Link Road, Jogeshwari (E), Mumbai 400 060

Expires on or after icon

Expires on or after

July, 2025

About Darzalex Injection

Darzalex Injection is used in the treatment of multiple myeloma, a type of cancer affecting plasma cells in the body. It is administered through an intravenous infusion into the veins under the supervision of a medical professional. The dosage and frequency of Darzalex Injection will be determined by your doctor based on your specific treatment needs, which may vary over time. It is crucial to follow your doctor's instructions precisely to avoid serious side effects. Patience is key, as it may take weeks or months before the benefits of the medication are noticeable. Do not discontinue its use unless advised by your doctor.

Common side effects of Darzalex Injection include infusion reactions such as swelling of the face, lips, mouth, tongue, or throat, along with difficulty in swallowing or breathing. This medication may also lead to a decrease in the number of blood cells, particularly white blood cells, making you more susceptible to infections. Regular blood tests will be necessary to monitor your blood cell counts while you are on this treatment.

It is important to inform your healthcare team about all the medications you are taking, as Darzalex Injection can interact with other medicines. This medication is not recommended for use during pregnancy or while breastfeeding. Both males and females undergoing treatment with Darzalex Injection should use effective contraception to prevent pregnancy.


Benefits

Darzalex Injection, when used in the treatment of multiple myeloma, plays a crucial role in addressing the underlying issue of bone destruction in the body. When suffering from multiple myeloma, the bones are being broken down at a quicker rate than they can be renewed, leading to weakness, pain, and an increased risk of fractures. By incorporating Darzalex Injection into your treatment regimen, alongside other cancer therapies like chemotherapy, you are not only effectively targeting the cancerous cells but also curbing their growth and preventing them from spreading to other areas of the body. This medication significantly boosts the overall survival rate of individuals battling multiple myeloma, highlighting its importance in managing the condition. To ensure optimal results, it is essential to adhere closely to your doctor's guidance throughout the treatment process. Additionally, your healthcare provider may recommend calcium and Vitamin D3 supplements, particularly if your blood calcium levels are not elevated, as these have also proven to be beneficial in complementing the treatment with Darzalex Injection. By following your doctor's instructions diligently and incorporating these supportive measures, you can reap the maximum benefits from this medication in your fight against multiple myeloma.


How to use the Darzalex Injection

To use Darzalex Injection, it is important to remember that only your doctor or nurse should administer this medicine. You should not try to give yourself the injection. It is crucial to follow your healthcare provider's instructions carefully. They will determine the correct dosage and the best way to administer the medication based on your specific condition. Before receiving the injection, your doctor or nurse will prepare the medication and ensure proper administration. Be sure to ask any questions you may have about the injection process so you fully understand how to use Darzalex safely and effectively for your treatment.


Uses of Darzalex Injection

Darzalex Injection is commonly used in patients with multiple myeloma, a type of cancer that affects plasma cells in the bone marrow. This medication is used in combination with other cancer treatments to help slow down the progression of the disease and improve overall survival. Darzalex Injection works by targeting a specific protein on the surface of myeloma cells, helping the immune system attack and destroy these cancerous cells. This treatment can be an important part of managing multiple myeloma and may be prescribed by healthcare providers based on individual patient needs and treatment plans.


What conditions Darzalex Injection treats?

Darzalex Injection is used to treat multiple myeloma, a type of cancer affecting plasma cells. This medicine helps by killing cancerous cells, preventing their growth and spread, and improving bone strength. It is typically given as an IV infusion under medical supervision, with dosage and frequency determined by the doctor. Common side effects include infusion reactions and decreased white blood cell count. Regular blood tests are necessary, and it is important to inform your healthcare team of all medications being used. Darzalex is not recommended during pregnancy or breastfeeding, and effective contraception is vital during treatment to avoid pregnancy.


Should you consult a doctor?

If you experience an infusion reaction with symptoms such as swollen face, lips, mouth, tongue, or throat, difficulty swallowing or breathing, it is important to seek immediate medical attention. Additionally, if you notice any persistent side effects like back pain, constipation, diarrhea, dizziness, fatigue, fever, insomnia, joint pain, low blood platelets, nausea, breathlessness, upper respiratory tract infection, or vomiting, consult your doctor. Decreased white blood cell count can increase susceptibility to infections, requiring regular blood tests. Let your healthcare team know all medications you are taking, as interactions can occur. Avoid using Darzalex during pregnancy or breastfeeding, and use effective contraception. It may take time to see benefits, so do not stop without doctor's advice. If any concerns arise while taking Darzalex, seek guidance from your healthcare provider.


Side effects of Darzalex Injection

When using Darzalex Injection, you may experience various side effects. These side effects are usually mild and tend to go away as your body gets used to the medicine. However, if they persist or cause you concern, it's essential to consult your doctor. Some common side effects include back pain, constipation, diarrhea, dizziness, fatigue, fever, infusion reaction, insomnia, joint pain, low white blood cell count, low blood platelets, nausea, breathlessness, upper respiratory tract infections, and vomiting. These side effects are important to be aware of, but they do not occur in everyone.


Safety advice

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liver

When it comes to the safety of using Darzalex Injection for patients with liver disease, the available information indicates that it is likely safe. It has been noted that there may not be a requirement for adjusting the dose of Darzalex Injection specifically for patients with liver issues based on the limited data currently available. However, it is always crucial to consult your doctor before starting or continuing any treatment involving Darzalex Injection to ensure the best course of action for your individual health needs.

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kidney

Darzalex Injection may be safe for use in patients with kidney disease. Current data indicates that adjusting the dose of Darzalex Injection may not be necessary for these patients. It is advisable to consult your doctor.

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alcohol

It is unclear whether it is safe to drink alcohol while taking Darzalex Injection. Please seek advice from your healthcare provider.

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driving

Darzalex Injection typically does not impact your driving ability.

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pregnancy

Darzalex Injection may not be safe to use during pregnancy. Animal studies have shown potential harm to the developing baby. Your doctor will consider the risks and benefits before prescribing. Seek advice from your doctor.

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breastfeeding

Darzalex Injection is not recommended during breastfeeding due to potential harm to the baby from the drug passing into breastmilk.


Consumption warning before consuming Darzalex Injection

Before consuming Darzalex Injection for the treatment of multiple myeloma, it is important to be aware of certain precautions. This medication is administered through an IV infusion under medical supervision, with the dosage and frequency determined by your doctor. It is crucial to follow your doctor's instructions precisely to avoid serious side effects.

Common side effects include infusion reactions like swelling of the face, lips, mouth, tongue, or throat, as well as difficulty swallowing or breathing. Darzalex may also lead to a decrease in white blood cells, increasing the risk of infections. Regular blood tests are necessary to monitor blood cell levels during treatment.

Inform your healthcare team about all medications you are currently taking, as interactions can occur. It is not recommended to use Darzalex during pregnancy or while breastfeeding. Both males and females should use effective contraception during treatment to prevent pregnancy. Be aware that it may take some time to see the benefits of this medication and do not discontinue it without your doctor's guidance.


Related lab tests

For patients receiving Darzalex Injection, it is important to monitor their Albumin/Globulin Ratio in the serum. This test helps assess the overall protein balance in the blood, which can be impacted by the treatment. Additionally, monitoring calcium levels is crucial as Darzalex can affect calcium regulation in the body. Keeping track of the Complete Blood Count is essential to check for any changes in the blood cells that may occur during the treatment. Lastly, regular Kidney Function Tests are necessary as Darzalex can impact kidney function. These lab tests play a vital role in monitoring the patient's health and ensuring the safe and effective use of Darzalex Injection.


Additional Information

Habit FormingNo
Chemical ClassCarboxylic Acid Derivative
Therapeutic Class-
Action Class-

FAQs


Disclaimer

The information provided on this website is to the best of our abilities to ensure it is accurate, reliable, and reviewed by a team of professionals. It should not be used to diagnose, prevent, or cure any health problem. The information presented here is not intended to create a doctor-patient relationship or replace a registered medical practitioner's advice, diagnosis, or treatment. The absence or provision of any information or warning regarding any medicine should not be assumed as an implied or explicit assurance of safety or efficacy. We highly recommend consulting your registered medical practitioner for all queries or doubts related to your medical condition. Do not ignore professional medical advice or delay seeking it based on the content encountered on our website. We intend to support, not replace, the doctor-patient relationship.

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Dr. Abdullah Khan

MBBS - General Medicine

Last update on 01-Oct-2024