Darnesp 40 Injection
By Darnesp
Rx
0ml Injection in a Prefilled syringe

Composition
Darbepoetin alfa(40mcg)

Manufacturer - Adonis Laboratories Pvt Ltd
C-6, GROMA House, APMC Market ,Sector 19, Vashi, Navi Mumbai – 400 703

Expires on or after
July, 2025
About Darnesp 40 Injection
Darnesp 40 Injection is a medication used to treat anemia, which can be caused by conditions like chronic kidney disease or chemotherapy. The way it works is by encouraging the bone marrow to make more red blood cells, which are essential for carrying oxygen throughout the body.
It is crucial to handle Darnesp 40 Injection with great care due to the potential for serious side effects. Therefore, it is advised to receive treatment from a doctor who is well-versed in administering this type of therapy. Adhering strictly to the doctor's instructions is important as the injection is given under the supervision of a healthcare professional.
Some common side effects of Darnesp 40 Injection include abdominal pain, high blood pressure, rash, pain at the injection site, breathlessness, cough, and swelling in the limbs. It's important to notify your doctor if you experience signs of very high blood pressure, such as severe headaches, vision problems, nausea, vomiting, or seizures.
Regular blood tests may be conducted by your doctor to check the levels of electrolytes like potassium, hemoglobin, and blood cells in your system while on this medication. If you encounter issues like shortness of breath or skin rash, it is advisable to discontinue the medication and promptly consult with your doctor.
Prior to starting Darnesp 40 Injection, inform your doctor if you have a history of heart disease, high blood pressure, seizures, or strokes. For individuals who are pregnant, breastfeeding, or planning to become pregnant or breastfeed, seeking guidance from the doctor is recommended to ensure the safety of the treatment.
Benefits
Darnesp 40 Injection offers significant benefits in the treatment of anemia caused by chronic kidney disease and cancer chemotherapy. Anemia, a condition characterized by low red blood cell levels, can lead to symptoms like tiredness and weakness. In cases of chronic kidney disease, where kidney function deteriorates over time, anemia can become a complication. However, Darnesp 40 Injection works to increase red blood cell counts, helping to carry oxygen efficiently throughout the body. By addressing anemia, this injection can substantially improve the quality of life for individuals with chronic kidney disease.
Moreover, in the context of cancer chemotherapy, Darnesp 40 Injection plays a crucial role in managing anemia. Chemotherapy is known to cause various side effects, including a decrease in red blood cell levels. This medication stimulates the production of red blood cells in the bone marrow, effectively combating anemia in cancer patients undergoing chemotherapy. By regulating hemoglobin levels in the blood, Darnesp 40 Injection helps alleviate symptoms associated with anemia, providing relief and support during cancer treatment.
In summary, Darnesp 40 Injection offers dual benefits in addressing anemia related to chronic kidney disease and cancer chemotherapy. By boosting red blood cell production and improving hemoglobin levels, this medication not only treats anemia but also enhances the overall well-being and vitality of individuals facing these health challenges.
How to use the Darnesp 40 Injection
When using Darnesp 40 Injection, it is important to remember to always have a healthcare professional, like your doctor or nurse, administer the medicine to you. It is not recommended to try and administer this medicine on your own. This ensures that the injection is done correctly and helps to prevent any potential risks or complications. By following your healthcare provider's instructions and having them give you the injection, you can help ensure the safe and effective use of Darnesp 40 Injection for your specific medical needs. Remember, always seek the guidance of a healthcare professional when using this medicine.
Uses of Darnesp 40 Injection
Darnesp 40 Injection is commonly used for treating anemia caused by chronic kidney disease and anemia resulting from cancer chemotherapy. It is a medication that is injected to help increase the red blood cell count in the body. This treatment is essential for patients undergoing dialysis for kidney disease or receiving chemotherapy for cancer. By boosting red blood cell production, Darnesp 40 Injection helps improve symptoms of fatigue and weakness that often accompany these conditions. The medication is safe and effective when used as directed by a healthcare provider.
What conditions Darnesp 40 Injection treats?
Darnesp 40 Injection is prescribed to treat anemia, which can arise from chronic kidney disease or chemotherapy. Anemia occurs when the body lacks enough red blood cells to carry oxygen, leading to symptoms like fatigue. Chronic kidney disease gradually impairs kidney function and can result in anemia. Darnesp 40 Injection helps in increasing red blood cell levels and alleviating anemia symptoms. Similarly, in cancer patients undergoing chemotherapy, this injection boosts red blood cell production to address chemotherapy-induced anemia.
Should you consult a doctor?
If you experience symptoms of very high blood pressure such as severe headache, problems with eyesight, nausea, vomiting, or fits (seizures), it is crucial to seek immediate medical attention from a doctor. Additionally, if you develop shortness of breath or skin rash while using Darnesp 40 Injection, stop taking the medication and consult with your doctor promptly. Regular monitoring of blood tests by a healthcare professional is essential to check the levels of salts, hemoglobin, and blood cells in your blood. Inform your doctor before starting Darnesp 40 Injection if you have a history of heart disease, high blood pressure, seizure, stroke, or if you are pregnant, breastfeeding, or planning to become pregnant. It is important to follow your doctor's guidance diligently and report any persistent side effects or concerns to ensure safe and effective treatment.
Side effects of Darnesp 40 Injection
When taking Darnesp 40 Injection, you may experience some side effects. Most of these side effects are usually mild and temporary, happening as your body gets used to the medication. These may include abdominal pain, rash, breathlessness, cough, and injection site pain. Additionally, some individuals may also experience high blood pressure, peripheral edema, and procedural hypotension (low blood pressure). In rare cases, more serious side effects such as convulsions and thromboembolism may occur. It is important to discuss any persistent or concerning side effects with your doctor for proper evaluation and guidance.
Safety advice

liver
When using Darnesp 40 Injection, it is essential to proceed with caution, especially if you have a history of liver disease. Patients with liver issues may require a dose adjustment when using Darnesp 40 Injection. It is crucial to consult your doctor for proper guidance on the use of this medication in such cases.

kidney
Darnesp 40 Injection is considered safe for patients with kidney disease. It is not necessary to adjust the dose of Darnesp 40 Injection for these patients.

alcohol
It is not known if it is safe to drink alcohol while using Darnesp 40 Injection. Consult your doctor for guidance.

driving
When using Darnesp 40 Injection, it is noted that it generally does not impact your driving ability.

pregnancy
Darnesp 40 Injection may not be safe to use during pregnancy. Animal studies have shown potential harm to the developing baby. Your doctor will assess the benefits versus risks before prescribing. Consult your doctor for more information.

breastfeeding
Caution should be exercised if breastfeeding while using Darnesp 40 Injection due to possible harm to the baby through drug transmission in breastmilk.
Consumption warning before consuming Darnesp 40 Injection
Before using Darnesp 40 Injection for anemia caused by chronic kidney disease or chemotherapy, it is crucial to be aware of possible serious side effects. This medicine should only be administered under the supervision of a doctor experienced in this treatment. Adhere strictly to the doctor's instructions throughout the course.
Potential side effects include abdominal pain, elevated blood pressure, rash, injection site discomfort, breathlessness, cough, and swelling in limbs. Promptly notify your doctor if you experience signs of severe hypertension such as intense headache, visual disturbances, nausea, vomiting, or seizures.
Regular monitoring of blood electrolyte levels, hemoglobin, and blood cells is necessary. If you encounter breathing difficulties or skin rashes, discontinue use and seek medical advice immediately. It's essential to inform your doctor about any existing heart conditions, high blood pressure, history of seizures or stroke before starting treatment. Consult your physician if pregnant, breastfeeding, or planning to conceive to verify the safety of using this medication.
What if you forgot to take Darnesp 40 Injection?
If you happen to miss a dose of Darnesp 40 Injection, try to take it as soon as you remember. But, if it's close to the time for your next scheduled dose, it's better to just skip the missed one and continue with your normal dosing routine. Avoid taking a double dose to make up for the missed one. This helps maintain the right levels of the medication in your body and reduces the risk of any potential side effects or complications.
Related lab tests
Related Lab Tests for monitoring patients receiving Darnesp 40 Injection include a Complete Blood Count (CBC) and a Peripheral Smear Examination. These tests are important to assess the overall health status of the patient and monitor any potential side effects or complications that may arise from the treatment with Darnesp 40 Injection. A Complete Blood Count helps to evaluate the levels of different blood cells such as red blood cells, white blood cells, and platelets, providing valuable information about the patient's immune system and oxygen-carrying capacity. A Peripheral Smear Examination allows for a closer look at the blood cells under a microscope, helping to identify any abnormalities or irregularities that may not be apparent from the CBC results alone. Monitoring these lab tests regularly can help healthcare providers ensure the safe and effective use of Darnesp 40 Injection in patients.
Additional Information
Habit Forming | No |
Chemical Class | Amino Acids, Peptides, and Analogues |
Therapeutic Class | BLOOD RELATED |
Action Class | Erythropoiesis-stimulating agent (ESA) |
FAQs
Disclaimer
The information provided on this website is to the best of our abilities to ensure it is accurate, reliable, and reviewed by a team of professionals. It should not be used to diagnose, prevent, or cure any health problem. The information presented here is not intended to create a doctor-patient relationship or replace a registered medical practitioner's advice, diagnosis, or treatment. The absence or provision of any information or warning regarding any medicine should not be assumed as an implied or explicit assurance of safety or efficacy. We highly recommend consulting your registered medical practitioner for all queries or doubts related to your medical condition. Do not ignore professional medical advice or delay seeking it based on the content encountered on our website. We intend to support, not replace, the doctor-patient relationship.
₹2403
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Content verified by

Dr. Archana Prabhakar
MBBS, M.Med (Family Medicine)
Last update on 11-Feb-2025