Dargen 25 Injection

By Dargen

Rx

0ml Injection in a Prefilled syringe

Composition icon

Composition

Darbepoetin alfa(25mcg)

Manufacturer - Lupin Ltd icon

Manufacturer - Lupin Ltd

Lupin Ltd, 3rd floor Kalpataru Inspire, Off. W E Highway, Santacruz (East), Mumbai 400 055. India

Expires on or after icon

Expires on or after

July, 2025

About Dargen 25 Injection

Dargen 25 Injection is a medication used to treat anemia caused by chronic kidney disease or chemotherapy. Anemia is when the body has a low amount of red blood cells or hemoglobin. In chronic kidney disease, the kidneys are damaged and cannot filter the blood properly, leading to anemia. Dargen 25 Injection contains a protein called Darbepoetin alfa, which signals the bone marrow to produce more red blood cells. This medication helps to reverse anemia and reduce the need for blood transfusions. It is a biologic response modifier and erythropoiesis-stimulating protein.

Dargen 25 Injection should only be administered by a healthcare provider and not self-administered. It is important to follow all directions given by a doctor experienced in providing this medical therapy. Regular blood tests may be recommended to monitor the levels of electrolytes, hemoglobin, and blood cells in your blood. Common side effects of Dargen 25 Injection include abdominal pain, high blood pressure, rash, injection site pain, breathlessness, cough, and peripheral edema.

Before starting treatment with Dargen 25 Injection, inform your doctor if you have heart disease, high blood pressure, have had seizures or strokes, or if you are pregnant, breastfeeding, or planning to become pregnant. It is crucial to mention any other medications you are taking, especially if you have uncontrolled high blood pressure or a type of anemia caused by Darbepoetin alfa or Epoetin alfa. If you experience persistent side effects such as weakness, lightheadedness, fatigue, or pale skin, contact your doctor immediately.

Dargen 25 Injection helps stimulate the bone marrow to produce more red blood cells, which in turn helps to combat anemia associated with chronic kidney disease or chemotherapy. It is essential to use this medication under the close supervision of a healthcare professional to manage potential side effects and ensure effective treatment. Monitoring of blood tests and adherence to doctor's instructions are important aspects of managing treatment with Dargen 25 Injection.


Benefits

Dargen 25 Injection offers substantial benefits in the treatment of anemia in individuals with chronic kidney disease and those undergoing cancer chemotherapy. Anemia, a condition characterized by insufficient red blood cells to carry oxygen, is a common complication of chronic kidney disease. The injection works by boosting red blood cell levels, thereby alleviating symptoms such as tiredness and weakness. By addressing anemia, Dargen 25 Injection significantly enhances the quality of life for individuals struggling with chronic kidney disease.

Moreover, cancer patients undergoing chemotherapy often experience anemia as a side effect due to low red blood cell counts. Dargen 25 Injection plays a crucial role in stimulating the production of red blood cells in the bone marrow and regulating hemoglobin levels in the blood. This targeted approach effectively combats anemia in cancer patients undergoing chemotherapy, providing them with much-needed relief and support during their treatment journey. Overall, the use of Dargen 25 Injection in both chronic kidney disease and cancer chemotherapy settings offers tangible benefits by addressing anemia and improving overall well-being for patients dealing with these challenging conditions.


How to use the Dargen 25 Injection

When using Dargen 25 Injection, it is important to remember that only a doctor or nurse should administer this medicine. It should not be self-administered. This means you should not try to give yourself the injection. Allow a healthcare professional to handle the administration of Dargen 25 Injection to ensure proper dosage and safe delivery into your body. It is best to follow the instructions of your healthcare provider closely to ensure the effectiveness and safety of the treatment.


Uses of Dargen 25 Injection

Dargen 25 Injection is primarily used for the treatment of anemia in patients with chronic kidney disease or those undergoing cancer chemotherapy. In cases of chronic kidney disease, this medication helps to increase red blood cell production, thus addressing the anemia associated with the condition. Similarly, for individuals receiving cancer chemotherapy, Dargen 25 Injection is used to manage anemia resulting from the treatment. By stimulating the production of red blood cells, this medication can help improve overall health and well-being in these patient populations.


What conditions Dargen 25 Injection treats?

Dargen 25 Injection is used to treat anemia caused by chronic kidney disease or chemotherapy. Anemia occurs when the body lacks enough red blood cells to transport oxygen. Chronic kidney disease is a gradual loss of kidney function over time that can lead to anemia. The injection helps stimulate the production of red blood cells in the bone marrow, alleviating anemia symptoms like tiredness and weakness. Similarly, in cancer patients undergoing chemotherapy, Dargen 25 Injection assists in regulating hemoglobin and treating anemia resulting from low red blood cell count.


Should you consult a doctor?

When using Dargen 25 Injection for anemia related to chronic kidney disease or chemotherapy, it is crucial to seek a doctor's guidance. This medication can lead to severe side effects, making it essential to be under the care of an experienced healthcare provider. Follow your doctor's instructions diligently and take the injection only under proper medical supervision.

If you experience common side effects like abdominal pain, high blood pressure, rash, injection site pain, breathlessness, cough, or peripheral edema, inform your doctor immediately. Watch out for symptoms of very high blood pressure such as severe headache, vision issues, nausea, vomiting, or seizures, and seek medical help promptly if these occur.

Regular blood tests may be necessary to monitor electrolyte levels, hemoglobin, and blood cell counts. Cease the injection and consult your doctor if you notice shortness of breath or skin rash. Prior to starting Dargen 25 Injection, discuss any existing heart conditions, hypertension, seizures, or strokes with your doctor. If pregnant, nursing, or planning a pregnancy, consult your healthcare provider for personalized advice on the safety of this medication for you.


Side effects of Dargen 25 Injection

When using Dargen 25 Injection, some individuals may experience side effects as their body gets used to the medication. While most side effects are generally not serious and may go away on their own, it is important to consult your doctor if they persist or if you are concerned about them. Common side effects of Dargen 25 Injection may include abdominal pain, high blood pressure, rash, pain at the injection site, breathlessness, cough, peripheral edema, low blood pressure during procedures, convulsions, and thromboembolism. If you experience any of these side effects, it is advisable to seek medical advice.


Safety advice

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liver

Dargen 25 Injection should be used cautiously in individuals with liver disease. It may be necessary to adjust the dosage of the injection in such cases. It is important to consult your doctor regarding the use of Dargen 25 Injection if you have liver issues.

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kidney

Dargen 25 Injection is safe for patients with kidney disease. No dose adjustment is necessary for this population.

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alcohol

Consult your doctor when consuming alcohol with Dargen 25 Injection.

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driving

Dargen 25 Injection typically does not impact driving ability.

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pregnancy

Dargen 25 Injection may not be safe to use during pregnancy. Animal studies have shown potential harmful effects on the developing baby. Your doctor will carefully assess the benefits and risks before prescribing this medication. Please consult your doctor before using Dargen 25 Injection.

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breastfeeding

Caution is advised when using Dargen 25 Injection during breastfeeding as it may be unsafe. Limited evidence indicates potential harm to the baby through passage into breastmilk.


Consumption warning before consuming Dargen 25 Injection

Before consuming Dargen 25 Injection for anemia related to chronic kidney disease or chemotherapy, it's crucial to be aware of potential risks. This medication can have severe side effects, requiring careful oversight by an experienced healthcare provider. Adhere strictly to your doctor's instructions and receive the injection only under medical supervision.

Common side effects include abdominal pain, high blood pressure, rash, and injection site pain. Be vigilant for signs of elevated blood pressure such as severe headache, vision problems, nausea, vomiting, or seizures. Regular blood tests may be necessary to monitor your electrolyte levels and blood counts. Immediate medical attention is necessary if you experience shortness of breath or skin rash.

Inform your doctor if you have a history of heart disease, high blood pressure, seizures, or stroke. If you are pregnant, breastfeeding, or planning to conceive, consult your doctor regarding the safety of this medication for you.


What if you forgot to take Dargen 25 Injection?

If you forget to take your Dargen 25 Injection, try to take it as soon as you remember. But if it's almost time for your next dose, you can skip the missed one and continue with your usual schedule. Avoid taking a double dose to make up for the missed one.


Related lab tests

When you are prescribed Dargen 25 Injection, your healthcare provider may recommend certain lab tests to monitor your health. One important test is the Complete Blood Count (CBC), which provides information about your overall health by measuring different components of your blood, such as red blood cells, white blood cells, and platelets. This test helps to detect conditions like anemia, infections, and blood disorders. Another useful test is the Peripheral Smear Examination, where a sample of your blood is examined under a microscope to check the size, shape, and number of blood cells. This test helps in diagnosing conditions like anemia, infections, and certain blood disorders. In addition to these tests, other related lab tests that may be recommended include iron studies, erythropoietin levels, and reticulocyte count to further assess your blood health. Regular monitoring of these lab tests can help ensure that your treatment with Dargen 25 Injection is effective and safe.


Additional Information

Habit FormingNo
Chemical ClassAmino Acids, Peptides, and Analogues
Therapeutic ClassBLOOD RELATED
Action ClassErythropoiesis-stimulating agent (ESA)

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Disclaimer

The information provided on this website is to the best of our abilities to ensure it is accurate, reliable, and reviewed by a team of professionals. It should not be used to diagnose, prevent, or cure any health problem. The information presented here is not intended to create a doctor-patient relationship or replace a registered medical practitioner's advice, diagnosis, or treatment. The absence or provision of any information or warning regarding any medicine should not be assumed as an implied or explicit assurance of safety or efficacy. We highly recommend consulting your registered medical practitioner for all queries or doubts related to your medical condition. Do not ignore professional medical advice or delay seeking it based on the content encountered on our website. We intend to support, not replace, the doctor-patient relationship.

1841.95

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Content verified by

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Dr. Monie Riju Simon

MBBS - General Medicine

Last update on 11-Feb-2025