Crinone 8% Vaginal gel

By Crinone

Rx

1gm Vaginal gel in a Tube

Composition icon

Composition

Progesterone (Natural Micronized)(8% w/w)

Manufacturer - Merck Ltd icon

Manufacturer - Merck Ltd

L-2, J.R. Complex, Gate No. 4, Village Mandoli, Delhi-110 093, India

Expires on or after icon

Expires on or after

March, 2027

About Crinone 8% Vaginal gel

Crinone 8% Vaginal gel is a medication used to help restore menstrual cycles in women whose periods have ceased. This gel contains progesterone, a natural female hormone that plays a crucial role in regulating ovulation and menstruation. It is commonly prescribed to aid in infertility treatment and support conception by providing supplementary progesterone. It is important to strictly follow your doctor’s instructions regarding the dosage and duration of Crinone 8% Vaginal gel usage, as exceeding the recommended amount or duration can be harmful.

When using Crinone 8% Vaginal gel, you may experience side effects such as vaginal bleeding, discharge, or itching. Should any of these symptoms persist or worsen, it is imperative to inform your healthcare provider promptly. In rare instances, individuals may develop a severe allergic reaction to this medication, necessitating immediate medical attention. It is essential to disclose your medical history to your doctor, especially if you have a history of breast cancer, abnormal vaginal bleeding, liver disease, or other health conditions.

Before initiating treatment with Crinone 8% Vaginal gel, it is crucial to inform your healthcare provider about any existing liver, heart, or kidney issues, as well as conditions like asthma, diabetes, or depression. Your doctor may conduct various tests before and during your treatment to monitor your response. It is advised to abstain from using other vaginal products or creams concurrently with Crinone 8% Vaginal gel, as this may interfere with the medication's efficacy.

It is important to note that Crinone 8% Vaginal gel is not recommended for individuals with certain medical conditions such as abnormal vaginal bleeding, breast or genital cancer, blood clots, or porphyria disorder. Additionally, pregnant and breastfeeding women, as well as adolescents under 18 years of age, are generally advised against using this medication. The most common side effect reported with Crinone 8% Vaginal gel is breast tenderness, which should be discussed with your healthcare provider if it becomes bothersome. Regular monitoring and communication with your doctor are essential throughout your treatment with Crinone 8% Vaginal gel to ensure its effectiveness and safety.


Benefits

Crinone 8% Vaginal gel offers multiple benefits for women's health. In hormone replacement therapy, it helps alleviate distressing menopausal symptoms like hot flushes, night sweats, mood swings, vaginal dryness, and reduced sex drive. By including progesterone, a crucial hormone alongside estrogen, this treatment can significantly enhance daily life and mood during menopause. While it might not address all symptoms, it is essential to follow your doctor's instructions for the best results.


Furthermore, Crinone 8% Vaginal gel is effective in treating female infertility by regulating ovulation and menstruation. Specifically designed with progesterone, it prompts the thickening of the uterine lining, preparing the uterus for a potential pregnancy. This increases the chances of successfully conceiving. It is crucial to adhere to the prescribed regimen to optimize the medicine's efficacy. In case of pregnancy, your doctor may recommend continuing with the treatment for a specified period to support a healthy pregnancy.


Crinone 8% Vaginal gel, containing 8%W/W Gel 1.125Gm of progesterone, supports ovulation, menstruation, and secretory changes in the uterine endometrium. By relaxing the uterus, preventing follicle maturation, and aiding in maintaining pregnancy, this medication offers a holistic approach to women's reproductive health.


How to use the Crinone 8% Vaginal gel

To use Crinone 8% Vaginal gel, start by following your doctor's instructions. Remember, this gel is only for vaginal use, so be sure to use it as directed. Before applying the gel, make sure to clean the genital area thoroughly. Prepare the applicator by getting it ready, then find a comfortable position where you can lean back or lie down with your knees bent and spread apart.


Once you are in position, carefully insert the applicator into your vagina until your hand touches your body. Gently press the air tank at the thick end of the applicator to release the gel into your vagina. Make sure to follow the dose and treatment duration recommended by your doctor based on your specific condition.


If you are using the vaginal spray instead, shake the bottle well before each use. Then, spray the contents from a distance of 5cm onto the affected area. Remember to always check the label for specific directions before using the spray.


After applying either the gel or the spray, remember to wash your hands thoroughly. Following these steps will help you use Crinone 8% Vaginal gel effectively and safely for your vaginal health.


Uses of Crinone 8% Vaginal gel

Crinone 8% Vaginal gel is used as a hormone replacement therapy for treating female infertility. It is specifically utilized to address female infertility issues. This vaginal gel plays a crucial role in hormone replacement therapy and is a common treatment for female infertility conditions.


What conditions Crinone 8% Vaginal gel treats?

Crinone 8% Vaginal gel may be used by women who are experiencing female infertility. Female infertility occurs when a woman is unable to become pregnant after trying for a year or when experiencing miscarriages or stillbirths. This condition can be challenging for women who are trying to conceive.


Should you consult a doctor?

It is crucial to seek a doctor if you experience unexplained vaginal bleeding while using Crinone 8% Vaginal gel. Additionally, if you have a medical history or suspicion of breast or genital organ cancer, blood clotting issues such as thrombophlebitis or thromboembolic disorder, history of stroke, or porphyria disorder, it is important to consult a healthcare provider before using this product. Furthermore, if you have experienced a missed abortion or have underlying medical conditions such as diabetes, frequent migraines, seizures, or a history of depression, it is advisable to inform your doctor before starting to use Crinone 8% Vaginal gel. Consulting a healthcare professional in these situations is essential to ensure the safety and appropriateness of using this product.


Side effects of Crinone 8% Vaginal gel

When using Crinone 8% Vaginal gel, some common side effects may occur as your body gets used to the medication. These can include vaginal bleeding, abdominal pain, headache, constipation, nausea, breast pain, and breast tenderness. In most cases, these side effects are temporary and do not need medical treatment. However, if they persist or you are concerned, it is important to consult your doctor. Additionally, if you experience an allergic reaction such as an itchy skin rash, it is essential to stop using the gel immediately and seek medical advice. Your doctor can provide guidance on how to manage these side effects and determine the best course of action for your individual situation.


Safety advice

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liver

Crinone 8% Vaginal gel has not shown any interaction or issues related to the liver. It is important to keep in mind that no specific caution or safety advice has been identified in relation to the liver with the use of this product. If you have any concerns or underlying liver conditions, it is best to consult with your doctor before using Crinone 8% Vaginal gel.

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kidney

Consult with your doctor for proper guidance before using Crinone 8% Vaginal gel.

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alcohol

No interaction has been found between alcohol and Crinone 8% Vaginal gel. It is advised to consult your doctor regarding alcohol consumption during pregnancy.

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driving

No interaction found with Crinone 8% Vaginal gel and driving.

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pregnancy

Crinone 8% Vaginal gel is considered safe for use during pregnancy. Studies indicate minimal risk to the baby's development.

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breastfeeding

Crinone 8% Vaginal gel is considered safe to use while breastfeeding. Research shows that the gel does not transfer to breastmilk in high quantities, posing no harm to the baby.


Age above 75(Geriatrics)

Safety and effectiveness of Crinone 8% Vaginal gel use in elderly patients (over 65 years of age) have not been established. Consult your doctor for advice.


Age below 6 months(Pediatrics)

Crinone 8% Vaginal gel is not recommended for use in children and adolescents (under 18 years of age). Consult child’s doctor for advice.


Consumption warning before consuming Crinone 8% Vaginal gel

Before using Crinone 8% Vaginal gel, check if you are allergic to any of its components or have conditions such as unexplained vaginal bleeding, porphyria, cancer, thrombophlebitis, missed abortion, or miscarriage. Inform your doctor about your health status and medications to prevent any potential side effects or interactions. This gel is not suitable for children.


Disease interactions

When using Crinone 8% Vaginal gel, it's essential to consider potential interactions with certain disease conditions. These conditions include porphyria, breast or genital cancer, abnormal vaginal bleeding resulting from miscarriage or missed abortion, blood clots or stroke, as well as liver disease or abnormal liver tests. It is important to be aware of these possible interactions to ensure the safe and effective use of the gel in managing vaginal health. Therefore, if you have any of these health conditions, it is advisable to consult with a healthcare provider before using Crinone 8% Vaginal gel to avoid any adverse effects.


What if you forgot to take Crinone 8% Vaginal gel?

If you forget to use a dose of Crinone 8% Vaginal gel, try to use it as soon as you remember. But if it's close to the time for your next dose, then skip the missed one and continue with your normal dosing schedule. It's important to stay consistent with using the gel regularly as directed for the best results.


What happens if you take overdose of Crinone 8% Vaginal gel?

In the case of accidental overdose of Crinone 8% Vaginal gel, it is important to seek prompt medical attention. If you or someone else has used too much of the gel, consulting a doctor immediately or visiting the nearest hospital is advised. Overdosing on the vaginal gel can lead to potential complications, so it is crucial to address the situation promptly.


Related lab tests

The "Crinone 8% Vaginal gel" may require certain lab tests to be done in order to monitor its effects and ensure it is safe for use. Some relevant lab tests that may be needed include Anti Mullerian Hormone, which helps assess ovarian reserve and fertility potential. Glycosylated Hemoglobin test can provide information about blood sugar levels over a period of time, which is important for individuals with diabetes or at risk of diabetes. Testosterone Total test measures the level of testosterone in the body, which can impact sexual health and overall well-being. Thyroid Stimulating Hormone test evaluates thyroid function, which is important for metabolism and overall health. Additionally, other lab tests that may be relevant include saline-infusion sonography and ultrasound to assess the vaginal and reproductive health.


Additional Information

Habit FormingNo
Chemical ClassProgesterone Derivative
Therapeutic ClassGYNAECOLOGICAL
Action ClassNatural Progesterone

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Disclaimer

The information provided on this website is to the best of our abilities to ensure it is accurate, reliable, and reviewed by a team of professionals. It should not be used to diagnose, prevent, or cure any health problem. The information presented here is not intended to create a doctor-patient relationship or replace a registered medical practitioner's advice, diagnosis, or treatment. The absence or provision of any information or warning regarding any medicine should not be assumed as an implied or explicit assurance of safety or efficacy. We highly recommend consulting your registered medical practitioner for all queries or doubts related to your medical condition. Do not ignore professional medical advice or delay seeking it based on the content encountered on our website. We intend to support, not replace, the doctor-patient relationship.

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Dr. Abdullah Khan

MBBS - General Medicine

Last update on 01-Oct-2024