Calquence 100mg Capsule

By Calquence

Rx

12 Capsule in a Boxes

Composition icon

Composition

Acalabrutinib(100mg)

Manufacturer - AstraZeneca icon

Manufacturer - AstraZeneca

Corporate & Registered Office, Block N1, 12th Floor, Manyata Embassy Business Park, Rachenahalli, Outer Ring Road, 560045, Bangalore

Expires on or after icon

Expires on or after

July, 2025

About Calquence 100mg Capsule

Calquence 100mg Capsule is a medication prescribed for the treatment of blood cancer in individuals aged 18 years and above who have previously undergone at least one cancer treatment. It is essential to note that the safety and effectiveness of this drug in children have not been determined. This capsule is taken orally, and it is recommended to be consumed with food or between meals as directed by your healthcare provider. Maintaining a consistent schedule for taking this medicine is crucial to ensure its optimal effectiveness, and the duration of use should be as per your doctor's instructions. It may take some time, possibly several weeks or months, before experiencing the full benefits of the treatment.

Common side effects associated with Calquence 100mg Capsule include anemia, neutropenia, upper respiratory tract infection, thrombocytopenia, headache, diarrhea, and musculoskeletal pain. If these side effects become bothersome or severe, it is important to inform your doctor promptly, as they may provide guidance on managing or preventing these symptoms. Patients with a medical history of bleeding disorders, heart or liver conditions, prior radiation therapy, or any infections should inform their healthcare provider before starting this medication. The risk of bleeding may escalate if the patient is also taking blood-thinning medications alongside Calquence 100mg Capsule.

It is crucial to communicate all medications being used to your doctor to prevent potential interactions with Calquence 100mg Capsule, as this drug can affect or be affected by other medicines. Immediate medical attention is necessary if unusual bruising or bleeding, dark or bloody stools, sore throat, or any other serious symptoms are observed during the treatment. Since this medication can decrease the blood cell count, leading to heightened susceptibility to infections, regular blood tests are recommended to monitor blood cells, kidney, liver, and heart functions throughout the treatment period.

Both males and females undergoing treatment with Calquence 100mg Capsule are advised to use effective contraception to prevent pregnancy. Proper communication with your healthcare provider and adherence to prescribed guidelines are crucial for the safe and effective use of this medicine in the management of blood cancer.


Benefits

Calquence 100mg Capsule is a treatment for blood cancer, known as leukemia, which affects the body's blood-forming tissues and weakens the immune system's ability to fight infection. This medication works by killing cancer cells and preventing their growth and multiplication. It is a powerful drug that should be used cautiously, and it is essential to consult with a doctor to understand the potential risks and benefits before starting treatment. It is important to avoid consuming alcohol while taking Calquence 100mg Capsule. Additionally, any persistent side effects should be promptly reported to the doctor. Overall, Calquence 100mg Capsule offers hope as a targeted therapy in the fight against blood cancer, helping to improve outcomes and quality of life for patients.


How to use the Calquence 100mg Capsule

When using Calquence 100mg Capsule, it is important to follow the instructions provided by your doctor regarding the dose and duration of use. You can take the capsule with or without food, although it is recommended to take it at the same fixed time each day. This will help maintain a consistent level of the medication in your body. Make sure to not exceed the prescribed dose or duration without consulting your doctor. If you have any questions or concerns about how to use Calquence 100mg Capsule, do not hesitate to ask your healthcare provider for clarification.


Uses of Calquence 100mg Capsule

Calquence 100mg Capsule are primarily used for the treatment of blood cancer. Specifically, it is indicated for patients with certain types of blood cancer to help manage and control their condition. By targeting specific enzymes in the body, Calquence works to suppress the growth of cancer cells and inhibit their spread. This medication is prescribed by healthcare professionals as part of a comprehensive treatment plan for blood cancer patients to help improve their overall health and quality of life. It is important to follow your doctor's instructions carefully and take Calquence exactly as directed to maximize its effectiveness in treating blood cancer.


What conditions Calquence 100mg Capsule treats?

Calquence 100mg Capsule is used in the treatment of blood cancer, also known as leukemia. This type of cancer affects the blood-forming tissues, which weakens the body's ability to fight infections. The medication works by killing or halting the growth of cancer cells. It is important to understand that this medicine is potent and has potential risks, so discussing the benefits and risks with your doctor is crucial before starting treatment. It is advised to avoid alcohol consumption while on this medication and to report any persistent side effects to your doctor promptly.


Should you consult a doctor?

If you experience any bothersome or severe side effects from taking Calquence 100mg Capsule, it is essential to seek medical attention promptly. These side effects can include anemia, decreased white blood cell count, upper respiratory tract infection, low blood platelets, headache, diarrhea, and musculoskeletal pain. Additionally, if you have a medical history of bleeding disorders, heart or liver disease, or are taking blood thinners, it is crucial to inform your doctor. Contact your healthcare provider immediately if you notice any unusual bruising, bleeding, dark stools, sore throat, or signs of infection.

Regular monitoring through blood tests is necessary during treatment to check blood cell counts and assess the function of vital organs like the kidneys, liver, and heart. Given that Calquence 100mg Capsule can reduce blood cell numbers and increase susceptibility to infections, it is vital to consult your doctor for any unusual symptoms or concerns. Effective contraception should be used by both men and women during treatment to prevent pregnancy. Remember to follow your doctor's prescribed dose and schedule for optimal benefits and to avoid missing any doses.


Side effects of Calquence 100mg Capsule

When taking Calquence 100mg Capsule, some side effects may occur as your body gets used to the medicine. These side effects generally do not need medical attention and may go away on their own. However, it's important to consult your doctor if these side effects persist or if you are concerned about them. Common side effects of Calquence 100mg Capsule may include anemia (low red blood cell count), decreased white blood cell count (neutrophils), upper respiratory tract infection, low blood platelets, headache, diarrhea, and musculoskeletal pain (affecting bones, muscles, or joints). If you experience any of these side effects, discuss them with your healthcare provider to ensure proper management and care.


Safety advice

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liver

Based on the available data, Calquence 100mg Capsule is deemed safe for use in individuals with liver disease. It is indicated that there may not be a requirement for adjusting the dosage of Calquence 100mg Capsule in patients with liver issues. However, it is highly recommended to consult your doctor before taking this medication if you have any liver conditions to ensure proper guidance and supervision.

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kidney

Calquence 100mg Capsule is considered safe for use in patients with kidney disease, and there is limited data indicating that dose adjustment may not be necessary. It is advisable to consult your doctor before use.

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alcohol

Consult your doctor when consuming alcohol with Calquence 100mg Capsule.

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driving

When taking Calquence 100mg Capsule, it typically does not impact your driving ability.

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pregnancy

Calquence 100mg Capsule may not be safe to use during pregnancy. Animal studies suggest potential harm to the developing baby. Your doctor will consider the risks and benefits before prescribing this medication. Please consult your doctor before using it.

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breastfeeding

Caution is advised while breastfeeding as Calquence 100mg Capsule may not be safe. Limited data indicates that the drug can pass into breastmilk and potentially harm the baby.


Consumption warning before consuming Calquence 100mg Capsule

Before consuming Calquence 100mg Capsule, be aware that this medication is specifically for adults over 18 years old who have undergone previous cancer treatments. It is not recommended for children due to potential safety concerns. Ensure to take the capsule orally as directed by your doctor, either with food or between meals. Maintain a consistent schedule to avoid missing doses and follow the prescribed duration faithfully.

Be alert to potential side effects like anemia, infections, headaches, and digestive issues. If these symptoms persist or worsen, consult your doctor promptly. Disclose any history of bleeding disorders, cardiac complications, or liver diseases to your healthcare provider, as Calquence may pose risks in these cases. It is crucial to inform your doctor about all medications you are currently taking, including blood thinners, to prevent adverse interactions.

Regular blood tests are necessary during treatment to monitor blood cell counts and overall organ function. Additionally, practicing effective contraception is essential for both male and female patients to avert pregnancy risks while using Calquence 100mg Capsule.


What if you forgot to take Calquence 100mg Capsule?

If you forget to take your scheduled dose of Calquence 100mg Capsule, try to take it as soon as you remember. But if it's close to the time for your next dose, just skip the missed one and continue with your usual dosing schedule. Remember not to take a double dose to make up for the missed one. It's important to stay on track with your medication routine to ensure the best results.


Related lab tests

When taking Calquence 100mg Capsule, it is important to monitor certain lab tests to ensure your safety and health. Two important related lab tests are the Complete Blood Count (CBC) and Peripheral Smear Examination.

A Complete Blood Count (CBC) provides valuable information about the different types of blood cells in the body, including red blood cells, white blood cells, and platelets. This test helps healthcare providers assess overall health, detect a variety of disorders such as anemia or infection, and monitor the effects of certain medications like Calquence 100mg Capsule.

A Peripheral Smear Examination involves examining a sample of blood under a microscope to evaluate the size, shape, and number of blood cells. This test can provide additional information about the blood cells that may not be captured by a CBC alone. It can help diagnose conditions like anemia, infections, and certain types of leukemia.

Regular monitoring of these lab tests can help healthcare providers track your response to Calquence 100mg Capsule and detect any potential side effects early on. Be sure to follow your healthcare provider's guidance on when to perform these tests and discuss any concerns or questions you may have.


Additional Information

Habit FormingNo
Chemical ClassPhenylimidazoles
Therapeutic Class-
Action Class-

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Disclaimer

The information provided on this website is to the best of our abilities to ensure it is accurate, reliable, and reviewed by a team of professionals. It should not be used to diagnose, prevent, or cure any health problem. The information presented here is not intended to create a doctor-patient relationship or replace a registered medical practitioner's advice, diagnosis, or treatment. The absence or provision of any information or warning regarding any medicine should not be assumed as an implied or explicit assurance of safety or efficacy. We highly recommend consulting your registered medical practitioner for all queries or doubts related to your medical condition. Do not ignore professional medical advice or delay seeking it based on the content encountered on our website. We intend to support, not replace, the doctor-patient relationship.

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Dr. Monie Riju Simon

MBBS - General Medicine

Last update on 11-Feb-2025