Bonitar 400 Tablet

By Bonitar

Rx

10 Tablet in a Strip

Composition icon

Composition

Bosutinib(400mg)

Manufacturer - Sun Pharmaceutical Industries Ltd icon

Manufacturer - Sun Pharmaceutical Industries Ltd

Plot no 107/108,Namli block , Ranipool, East Sikkim 737135

Expires on or after icon

Expires on or after

July, 2025

About Bonitar 400 Tablet

Bonitar 400 Tablet is a medication used to treat a type of blood cancer called chronic myeloid leukemia. This form of leukemia is characterized by the excessive production of immature white blood cells, which can weaken the body's ability to fight infections. Bonitar 400 Tablet works by inhibiting the abnormal proteins responsible for the growth of cancerous cells. By slowing down the multiplication of these cells, the medication helps in reducing the progression of the disease and prevents it from spreading to other parts of the body.

It is important to follow your doctor's instructions when taking Bonitar 400 Tablet. Your doctor will determine the appropriate dosage and duration of treatment for your condition. The medication can be taken with or without food, but it is essential to take it regularly at the same time each day to help you remember. Do not stop taking the medicine suddenly; continue taking it as prescribed by your doctor.

Like any medication, Bonitar 400 Tablet may cause side effects. Common side effects include respiratory tract infections, low blood platelets, anemia, headaches, and gastrointestinal issues like diarrhea, vomiting, and abdominal pain. If you experience any of these side effects, inform your doctor. It is important to note that some side effects may require medical attention, especially if they persist or worsen over time.

Before starting treatment with Bonitar 400 Tablet, inform your doctor about any preexisting medical conditions you may have and disclose all other medications you are currently taking. Pregnant and breastfeeding women should avoid using this medication as it can harm the developing baby. Additionally, it is essential to be cautious if you have liver/kidney diseases, gastrointestinal issues, myelosuppression, or other conditions, as Bonitar 400 Tablet may worsen these conditions.

Remember, seek immediate medical attention if you experience severe headaches, vision changes, or other concerning symptoms while using Bonitar 400 Tablet. It is crucial to prioritize your health and follow your doctor’s guidance throughout the treatment process.


Benefits

Bonitar 400 Tablet, containing Bosutinib, which is a kinase inhibitor, offers significant benefits in treating blood cancer, specifically Chronic Myeloid Leukaemia. This type of cancer, affecting white blood cells, can weaken the body's immune system's ability to fight infections. The medication works by targeting and killing cancer cells while also preventing their growth and multiplication. By inhibiting the action of abnormal proteins responsible for the rapid division of cancerous cells, Bonitar 400 Tablet effectively halts the abnormal growth of cancer cells. This action contributes to reducing the spread of cancer to other parts of the body. It is important to note that during the course of treatment with Bonitar 400 Tablet, individuals should refrain from consuming alcohol and ensure adequate hydration by drinking plenty of water.


How to use the Bonitar 400 Tablet

To use Bonitar 400 Tablet, follow your doctor's instructions carefully. Take the medicine in the dose and duration recommended by your doctor. Swallow the tablet whole with a glass of water. Avoid chewing, crushing, or breaking the tablet. You can take Bonitar 400 Tablet with or without food, but it is advisable to take it at the same time each day for consistency. Remember not to exceed the prescribed dosage. If you have any questions or concerns about how to use Bonitar 400 Tablet, consult your doctor for further guidance.


Uses of Bonitar 400 Tablet

Bonitar 400 Tablet is commonly used to treat a type of blood cancer known as Philadelphia chromosome-positive chronic myeloid leukemia (CML). This medication is specifically designed to target and manage this particular form of leukemia. By specifically addressing the Philadelphia chromosome-positive aspect of CML, Bonitar 400 Tablet helps in the treatment and control of this type of blood cancer.


What conditions Bonitar 400 Tablet treats?

Bonitar 400 Tablet is used to treat Philadelphia chromosome-positive (Ph+) chronic myeloid leukemia. This type of leukemia, which is a form of blood cancer, results in the overproduction of immature white blood cells in the bone marrow. This leads to a weakened immune system, making it difficult for the body to fight infections. Ph+ chronic myeloid leukemia is characterized by a specific chromosome abnormality known as the Philadelphia chromosome, which triggers the production of abnormal white blood cells. Symptoms of this condition may include fatigue, fever, weight loss, and loss of appetite.


Should you consult a doctor?

If you experience severe headaches, swelling in one leg, pain while breathing, changes in vision, or hearing changes while taking Bonitar 400 Tablet, it is important to seek immediate medical attention. Additionally, if you notice persistent side effects such as abdominal pain, nausea, vomiting, diarrhea, headache, cough, low blood platelets, anemia, nasopharyngitis, respiratory tract infection, decreased white blood cell count, breathlessness, or increased liver enzymes, consult your doctor. It is essential to inform your healthcare provider about any bothersome symptoms so they can provide guidance on managing or preventing them. Prior to starting Bonitar 400 Tablet, discuss your preexisting medical conditions and current medications with your doctor. Pregnant and breastfeeding women should avoid taking this medication due to potential harm to the developing baby. Remember to take Bonitar 400 Tablet as prescribed by your doctor, without suddenly stopping the treatment, to ensure its effectiveness in managing chronic myeloid leukemia.


Side effects of Bonitar 400 Tablet

When taking Bonitar 400 Tablet, some common side effects may occur. These side effects can include abdominal pain, nausea, vomiting, and diarrhea. You may also experience a headache, cough, and respiratory tract infections. Other side effects could involve low blood platelets, resulting in symptoms like anemia or increased risk of bleeding. In some cases, you might encounter a decrease in white blood cell count, specifically neutrophils, which can affect your immune system. Breathlessness may also occur, alongside elevated liver enzymes. Additional side effects may manifest as nausea, diarrhea, painful urination, decreased platelet count, fatigue, edema, back pain, dizziness, and skin rash. It is essential to note that most of these side effects do not necessarily need medical attention as they may resolve as your body gets used to the medication. However, if these side effects persist or cause concern, it is advised to consult your doctor promptly.


Safety advice

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liver

When using Bonitar 400 Tablet, it's important to be cautious if you have liver disease. Patients with liver issues may require a dose adjustment for this medication. To ensure the safe and effective use of Bonitar 400 Tablet, it is advised to consult your doctor regarding any liver-related concerns before starting the treatment.

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kidney

Bonitar 400 Tablet requires caution in patients with kidney disease. Adjustments in dosage may be necessary. Consult your doctor for guidance.

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alcohol

Consult your doctor when consuming alcohol with Bonitar 400 Tablet.

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driving

It is not clear if Bonitar 400 Tablet affects driving skills. Avoid driving if you have symptoms that impact your focus or reaction time.

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pregnancy

Bonitar 400 Tablet is considered unsafe during pregnancy due to potential risks to the developing baby. However, in rare life-threatening situations, a doctor may prescribe it if benefits outweigh risks. Always consult your doctor before use.

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breastfeeding

Caution must be taken while breastfeeding if considering Bonitar 400 Tablet. Limited data suggests potential harm to the baby through breastmilk transmission.


Consumption warning before consuming Bonitar 400 Tablet

Before consuming Bonitar 400 Tablet, it is crucial to note certain precautions. Do not take this medication if you have allergies to it or any of its components. Inform your doctor about your medical history, current medications, and any conditions like liver or kidney disease, diabetes, cardiac issues, high blood pressure, gastrointestinal problems, myelosuppression, fluid retention, or hepatic toxicity. Bonitar 400 Tablet can have serious side effects in individuals with these conditions. It is also important to discuss pregnancy or plans for pregnancy with your doctor, as this medicine can harm the fetus. Breastfeeding should be stopped during treatment. This tablet is not recommended for individuals under 18 years. Additionally, avoid alcohol and smoking as they can worsen the effects of Bonitar 400 Tablet.


Disease interactions

Before taking Bonitar 400 Tablet, it is important to inform your doctor about any existing kidney or liver disease, gastrointestinal disorders, diabetes, hepatotoxicity, and cardiac disorders. These conditions can potentially interact with Bonitar 400 Tablet and may impact its effectiveness or cause adverse effects. It is crucial for your doctor to be aware of your medical history to ensure the safe use of this medication and to prevent any potential complications. Please disclose all relevant information about your health to your healthcare provider before starting treatment with Bonitar 400 Tablet.


What if you forgot to take Bonitar 400 Tablet?

If you forget to take a dose of Bonitar 400 Tablet, simply skip that missed dose and carry on with your regular dosing schedule. It is important not to take a double dose to make up for the missed one. Just take the next dose at the usual time and continue with your treatment plan as prescribed by your healthcare provider. Taking extra doses can increase the risk of experiencing unwanted side effects. If you have any concerns about missed doses or how to manage your medication schedule, consult your healthcare professional for guidance.


Related lab tests

Related Lab Tests for Bonitar 400 Tablet include Bcr-Abl Gene Translocation tests, which can be done qualitatively or quantitatively to check for specific genetic abnormalities. These tests help in monitoring the response to treatment and disease progression. Another important test is the Complete Blood Count, which provides information about different blood cells like red blood cells, white blood cells, and platelets. This test helps in assessing overall health and detecting any abnormalities. The Peripheral Smear Examination is also recommended as it involves examining a drop of blood under a microscope to assess the shape and size of blood cells. These tests are crucial in evaluating the effectiveness of Bonitar 400 Tablet treatment and monitoring any potential side effects.


Additional Information

Habit FormingNo
Chemical Class4-aminoquinolines
Therapeutic Class-
Action ClassTyrosine kinase inhibitors

FAQs


Disclaimer

The information provided on this website is to the best of our abilities to ensure it is accurate, reliable, and reviewed by a team of professionals. It should not be used to diagnose, prevent, or cure any health problem. The information presented here is not intended to create a doctor-patient relationship or replace a registered medical practitioner's advice, diagnosis, or treatment. The absence or provision of any information or warning regarding any medicine should not be assumed as an implied or explicit assurance of safety or efficacy. We highly recommend consulting your registered medical practitioner for all queries or doubts related to your medical condition. Do not ignore professional medical advice or delay seeking it based on the content encountered on our website. We intend to support, not replace, the doctor-patient relationship.

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Inclusive of all taxes

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Dr. Gowri Kulkarni

MBBS - General Medicine, DNB - Psychiatry, MRCGP [INT] Family Medicine, BSIC (BACP)

Last update on 11-Feb-2025