Biotrexate 500mg Injection

By Biotrexate

Rx

1 Injection in a Vial

Composition icon

Composition

Methotrexate(500mg)

Manufacturer - Biochem Pharmaceutical Industries icon

Manufacturer - Biochem Pharmaceutical Industries

BIOCHEM PHARMA, LG 113 / A, Xth Central Mall, Mahavir Nagar, 90ft Road, Next to D Mart, Kandivali - West, Mumbai - 400067.

Expires on or after icon

Expires on or after

April, 2026

About Biotrexate 500mg Injection

Biotrexate 500mg Injection is a medication utilized in the treatment of various types of cancers affecting different parts of the body like breasts, head, neck, lungs, blood, bone, lymph, and uterus. It is often prescribed alongside other medications as part of a combined treatment approach. The administration of Biotrexate 500mg Injection should always be overseen by a healthcare professional and should never be self-administered. The dosage and frequency of the injection will be determined by your doctor based on your specific condition, and it is crucial to follow their instructions precisely to avoid any potential serious side effects.

Patients taking Biotrexate 500mg Injection may not immediately experience the full benefits of the medication, as it may take several weeks or even months for the effects to become noticeable. It is essential to continue taking the medication as directed by your doctor and refrain from discontinuing it without their approval. Alcohol consumption should be avoided while on this medication as it can increase the risk of liver damage.

Common side effects of Biotrexate 500mg Injection include nausea, vomiting, appetite loss, abdominal discomfort, fatigue, mouth sores, and decreased white blood cell count. Your doctor may suggest taking folic acid to alleviate some of these side effects. If these side effects persist or worsen, it is important to inform your healthcare provider promptly. This potent medication may have severe adverse effects on some individuals, affecting their immune system and causing issues with blood, liver, or kidneys. Regular blood tests will be recommended by your doctor to monitor for any potential complications.

Prior to starting treatment with Biotrexate 500mg Injection, it is crucial to inform your healthcare provider about any existing stomach, liver, or kidney conditions, as well as any ongoing treatments for infections. Due to potential interactions with other medications, it is important to disclose all medications you are currently taking to your healthcare team. This medication is not advised during pregnancy or while breastfeeding, as it can harm the baby. It is also recommended to avoid pregnancy for a period of time after completion of the treatment. Various tests such as blood work, X-rays, and physical examinations may be conducted by your doctor before and during the course of treatment with Biotrexate 500mg Injection.

Biotrexate 500mg Injection contains Methotrexate, classified under Antimetabolites, and is used to manage a range of cancers such as acute lymphocytic lymphoma, meningeal leukemia, Non-Hodgkin’s Lymphoma, ovarian cancer, head and neck cancer, breast cancer, cervical cancer, lung cancer, bone cancer, and other challenging cancers. It is also indicated for severe psoriasis that is unresponsive to other treatments.

Patients should share their medical and family history, as well as their current medication list, with their doctor before receiving Biotrexate 500mg Injection. The medication is contraindicated in pregnant and nursing women, individuals with excessive alcohol intake, and those with liver or kidney disorders. Patients with lung, blood, or gastric issues should use caution when receiving this medication and should avoid caffeine-containing products during treatment.

Typical side effects that may occur after receiving Biotrexate 500mg Injection include headaches, nausea, vomiting, dizziness, and alterations in blood cell levels. Should any of these side effects worsen, it is recommended to seek medical advice promptly.


Benefits

Biotrexate 500mg Injection is a medication that falls under the category of antimetabolites and is known as a cytotoxic drug. This medication is particularly beneficial in the treatment of various types of cancers. By working to slow down the growth of cancer cells within the body, Biotrexate 500mg Injection proves to be an effective treatment option for conditions such as acute leukemias, non-Hodgkin’s lymphoma, and solid tumors present in areas like the breast, lung, bladder, head and neck, as well as cervical, ovarian, and testicular cancer.


In the realm of cancer treatment, Biotrexate 500mg Injection can be used either by itself or in combination with other medications to enhance its effectiveness. Despite being a potent and highly toxic medication, the benefits of Biotrexate 500mg Injection are substantial for individuals fighting against cancer. It is crucial to have an open discussion with your healthcare provider regarding the risks and advantages associated with this treatment.


Moreover, while undergoing treatment with Biotrexate 500mg Injection, it is advisable to abstain from consuming alcohol. Instead, prioritize staying well-hydrated by drinking plenty of water. By adhering to these recommendations, patients can optimize the benefits of Biotrexate 500mg Injection and support their overall well-being during the treatment process.


How to use the Biotrexate 500mg Injection

When using Biotrexate 500mg Injection, it is important to remember that only your doctor or nurse should administer this medicine. It should not be self-administered. This means that you should not try to inject the medicine on your own. Your healthcare provider will determine the correct dosage and monitor you during the process to ensure your safety and effectiveness of the treatment. By following these instructions and allowing a healthcare professional to administer Biotrexate 500mg Injection, you can help promote your well-being and maximize the benefits of the medication for your condition.


Uses of Biotrexate 500mg Injection

Biotrexate 500mg Injection is commonly used in the treatment of cancer. It is a medication that helps to combat cancer cells and slow down their growth. By targeting the cancer cells, Biotrexate 500mg Injection plays a vital role in managing different types of cancer. This injection is often prescribed by healthcare professionals as part of a comprehensive cancer treatment plan. It is important to follow the dosage instructions carefully and adhere to the treatment schedule to maximize the effectiveness of Biotrexate 500mg Injection in fighting cancer.


What conditions Biotrexate 500mg Injection treats?

Biotrexate 500mg Injection is a medication used to treat various types of cancers in different parts of the body such as breasts, head, neck, lungs, blood, bone, lymph, and uterus. It belongs to a class of drugs known as antimetabolites and works by slowing the growth of cancer cells. This medicine may be given alone or in combination with other treatments, as decided by your healthcare provider. It is important to follow your doctor's instructions carefully, as taking the wrong dose or too much can lead to serious side effects. Remember to avoid alcohol consumption during treatment and stay well-hydrated.


Should you consult a doctor?

If you experience severe side effects like persistent abdominal pain, ongoing indigestion, significant loss of appetite, continuous nausea, frequent vomiting, extreme tiredness, persistent mouth sores, or a noticeable decrease in white blood cell count while using Biotrexate 500mg Injection, it is important to seek medical help promptly. These symptoms may indicate a serious reaction to the medication that requires immediate attention from a healthcare provider. Additionally, if any side effects do not improve or worsen over time, it is advisable to consult your doctor for further evaluation and guidance. Remember, do not hesitate to contact your healthcare team if you have concerns or questions about the effects of Biotrexate 500mg Injection on your body. Your well-being is a top priority, and seeking timely medical assistance can ensure your safety and proper management of any potential complications.


Side effects of Biotrexate 500mg Injection

When using Biotrexate 500mg Injection, some individuals may experience certain side effects. It is important to note that most of these side effects do not usually require medical attention as they tend to diminish as your body gets used to the medication. However, if any of these side effects persist or cause concern, it is advisable to consult your doctor. Common side effects of Biotrexate 500mg Injection may include abdominal pain, indigestion, loss of appetite, nausea, vomiting, tiredness, mouth sores, and a decrease in white blood cell count.


Safety advice

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liver

When using Biotrexate 500mg Injection, it is important to be cautious if you have liver disease. It may be necessary to adjust the dosage of the injection, so consulting your doctor is advised. Patients with severe liver disease are not recommended to use Biotrexate 500mg Injection.

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kidney

Biotrexate 500mg Injection needs caution in kidney disease patients. Dose adjustment may be necessary. Regular kidney function test monitoring is recommended during treatment.

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alcohol

When taking Biotrexate 500mg Injection, it is advised to be cautious when consuming alcohol. Consult your doctor for more guidance.

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driving

When using Biotrexate 500mg Injection, be cautious when driving as it may reduce alertness, impact vision, and cause drowsiness and dizziness. Avoid driving if experiencing these side effects.

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pregnancy

Biotrexate 500mg Injection should be avoided during pregnancy as it can cause harm to the developing baby. Consult your doctor before using.

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breastfeeding

Caution should be exercised when considering Biotrexate 500mg Injection while breastfeeding as it is deemed unsafe. Potential risks include toxicity to the baby.


Consumption warning before consuming Biotrexate 500mg Injection

Before consumption of Biotrexate 500mg Injection, it is crucial to note that this medication is primarily used for treating cancer in various body parts. It should only be administered under the supervision of a healthcare professional and should not be self-administered. Your doctor will determine the appropriate dosage and frequency based on your specific treatment needs, which may change over time. Adhering strictly to your doctor's guidelines is essential to avoid serious side effects resulting from incorrect dosing.


Common side effects of Biotrexate 500mg Injection include nausea, vomiting, fatigue, and changes in blood cell count. It is important to report any persistent or worsening side effects to your doctor. Since this medicine may weaken your immune system, regular blood tests are necessary to monitor blood, liver, and kidney function.


Before starting Biotrexate 500mg Injection, inform your doctor about any existing stomach, liver, or kidney conditions, as well as any ongoing medications. This potent medication is not recommended during pregnancy or breastfeeding due to potential harm to the baby. Extra precautions, such as contraception, are advised post-treatment to prevent complications. Be prepared for regular medical monitoring during the course of treatment to ensure optimal safety and efficacy.


What if you forgot to take Biotrexate 500mg Injection?

If you forget to take a dose of Biotrexate 500mg Injection, it is important to consult your doctor for guidance. Missing a dose may affect the effectiveness of your treatment, so it's crucial to seek advice from your healthcare provider. By discussing the missed dose with your doctor, you can receive instructions on how to proceed to ensure you are still benefitting from the medication. It is always better to communicate any missed doses promptly to your healthcare team to manage your treatment effectively.


Additional Information

Habit FormingNo
Chemical ClassGlutamic Acid Derivatives
Therapeutic ClassANTI NEOPLASTICS
Action ClassAntimetabolite- Methotrexate

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Disclaimer

The information provided on this website is to the best of our abilities to ensure it is accurate, reliable, and reviewed by a team of professionals. It should not be used to diagnose, prevent, or cure any health problem. The information presented here is not intended to create a doctor-patient relationship or replace a registered medical practitioner's advice, diagnosis, or treatment. The absence or provision of any information or warning regarding any medicine should not be assumed as an implied or explicit assurance of safety or efficacy. We highly recommend consulting your registered medical practitioner for all queries or doubts related to your medical condition. Do not ignore professional medical advice or delay seeking it based on the content encountered on our website. We intend to support, not replace, the doctor-patient relationship.

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Dr. Abdullah Khan

MBBS - General Medicine

Last update on 01-Oct-2024