Besponsa 1mg Injection

By Besponsa

Rx

1 Injection in a Vial

Composition icon

Composition

Inotuzumab Ozogamacin(1mg)

Manufacturer - Pfizer Ltd icon

Manufacturer - Pfizer Ltd

The Capital, 1802, 18th Floor , Plot No. C-70, 'G' Block , Bandra Kurla Complex, Bandra East , Mumbai – 400051.

Expires on or after icon

Expires on or after

July, 2025

About Besponsa 1mg Injection

Besponsa 1mg Injection is a specialized medication known as a CD22-directed antibody-drug conjugate (ADC) primarily used to help adults who have relapsed or refractory B-cell precursor acute lymphoblastic leukemia (ALL). This medication is administered through an injection into the veins by a healthcare professional. The dosage will vary depending on the specific condition being treated and may be adjusted periodically. It is crucial to follow your doctor's instructions precisely to avoid severe side effects that could arise from incorrect dosing.

It is important to note that the effects of Besponsa 1mg Injection may not be immediately apparent, as it could take weeks or even months to observe any beneficial outcomes. It is essential to continue taking the medication as prescribed by your doctor unless advised otherwise. It is vital to understand that discontinuing the medication abruptly could be detrimental to the treatment's effectiveness.

Common side effects associated with Besponsa 1mg Injection include a decrease in various blood cells (red cells, white cells, and platelets), infections, fatigue, hemorrhage, fever, nausea, headache, elevated liver enzymes, and abdominal discomfort. If any of these side effects become bothersome or severe, it is crucial to inform your healthcare provider promptly. Your doctor may recommend possible strategies to alleviate or prevent these side effects during the course of treatment.

Before starting Besponsa 1mg Injection, it is imperative to inform your doctor about any medical history of bleeding disorders, heart or liver issues, past radiation treatments, or any ongoing infections. As this medication can interact with various other drugs, it is essential to disclose all medications you are currently taking to ensure safe and effective treatment. In case you experience unusual bruising or bleeding, dark or bloody stools, or a persistent sore throat, notify your healthcare provider immediately.

Besponsa 1mg Injection has the potential to reduce the blood cell count, leading to an increased susceptibility to infections. Regular blood tests are necessary to monitor blood cell counts and assess kidney, liver, and heart function throughout the treatment duration. Both males and females must practice effective contraception while undergoing treatment to prevent unintended pregnancies and ensure a safe course of therapy.


Benefits

Besponsa 1mg Injection is a beneficial treatment option for individuals suffering from Acute lymphoblastic leukemia, a type of blood cancer that weakens the body's immune system. This medication works by effectively killing or halting the growth of cancer cells, thereby preventing them from multiplying further. It is important to note that Besponsa 1mg Injection is a strong medicine with potential toxic effects, so it's crucial to have a thorough discussion with your healthcare provider regarding its risks and benefits. To ensure the best outcome, it is recommended to abstain from consuming alcohol while undergoing treatment with this drug and maintain proper hydration by drinking plenty of water. By following these guidelines and working closely with your doctor, you can maximize the benefits of Besponsa 1mg Injection in managing Acute lymphoblastic leukemia and improve your overall health and well-being.


How to use the Besponsa 1mg Injection

When using Besponsa 1mg Injection, it is important to remember that only your doctor or nurse should administer this medication. It should not be self-administered. Trust the expertise of your healthcare provider to properly give you the injection. Administering this injection correctly is crucial for its effectiveness and your safety. Follow their instructions carefully and do not try to handle the injection on your own. By allowing your doctor or nurse to give you Besponsa 1mg Injection, you are ensuring that the medication is properly administered, maximizing its benefits for your health.


Uses of Besponsa 1mg Injection

Besponsa 1mg Injection is commonly used in the treatment of acute lymphoblastic leukemia, a type of cancer affecting the blood and bone marrow. This medication is administered through injection to help combat the cancer cells and manage the symptoms associated with this condition. By targeting the abnormal white blood cells that characterize acute lymphoblastic leukemia, Besponsa 1mg Injection plays a crucial role in the overall treatment plan prescribed by healthcare professionals. This medication is an important part of the therapy regimen for individuals suffering from this specific type of leukemia.


What conditions Besponsa 1mg Injection treats?

Besponsa 1mg Injection is used to treat adults with relapsed or refractory B-cell precursor acute lymphoblastic leukemia (ALL), a type of blood cancer that weakens the body's infection-fighting ability. This medicine works by destroying or halting the growth of cancer cells, reducing their multiplication. It is crucial to follow your doctor's instructions carefully to avoid serious side effects such as decreased blood cells, infections, fatigue, and others. Regular blood tests and effective contraception are necessary during treatment to monitor and manage potential risks. Notify your doctor promptly if you have any concerns or notice unusual symptoms.


Should you consult a doctor?

Seek immediate medical attention if you notice unusual bruising or bleeding, dark stools, or a sore throat while using Besponsa 1mg Injection. Inform your doctor if you have a history of bleeding disorders, heart or liver issues, or past radiation treatment. Let your healthcare provider know about all medications you are taking, as interactions can occur. Regular blood tests are necessary during treatment to monitor blood cell levels and organ function. Effective contraception is vital during treatment to prevent pregnancy. Contact your doctor if side effects like decreased blood cells, infection, fatigue, hemorrhage, fever, nausea, headache, or abdominal pain persist. It may take time to see benefits, so do not stop treatment unless advised by your doctor.


Side effects of Besponsa 1mg Injection

When using Besponsa 1mg Injection, some common side effects may occur as your body gets used to the medication. These side effects usually do not require medical attention and will go away on their own. If any of these side effects persist or you are concerned about them, it is best to consult your doctor. Side effects of Besponsa 1mg Injection may include low blood platelets, decreased white blood cell count especially neutrophils and lymphocytes, which are essential for fighting infections. Other potential side effects include anemia, fatigue, hemorrhage, fever, nausea, headache, febrile neutropenia, and abdominal pain. In some cases, an increase in liver enzymes such as transaminase level, gamma-glutamyltransferase, and bilirubin in the blood may also occur. It is important to be aware of these side effects and seek medical advice if needed.


Safety advice

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liver

Besponsa 1mg Injection is considered safe for use in patients with liver disease. It is not necessary to adjust the dosage of Besponsa 1mg Injection specifically for individuals with liver conditions. This information suggests that individuals with liver issues can typically use this medication without concerns about liver-related complications.

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kidney

Limited information is available about using Besponsa 1mg Injection in patients with kidney disease. It is advisable to consult your doctor regarding this issue.

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alcohol

Consult your doctor when consuming alcohol with Besponsa 1mg Injection.

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driving

When using Besponsa 1mg Injection, it is unclear if it impacts driving ability. Avoid driving if you have symptoms that impair concentration and reaction time.

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pregnancy

Besponsa 1mg Injection may not be safe to use during pregnancy as animal studies show harmful effects on the developing baby. Your doctor will assess the benefits and risks before prescribing. Please consult your doctor before using.

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breastfeeding

Besponsa 1mg Injection may not be safe for use during breastfeeding. Limited evidence indicates the drug could enter breastmilk and potentially harm the baby.


Consumption warning before consuming Besponsa 1mg Injection

Before consuming Besponsa 1mg Injection, it is crucial to be aware of certain important information. This medication is a CD22-directed antibody-drug conjugate used for treating adults with relapsed or refractory B-cell precursor acute lymphoblastic leukemia. It is administered via injection into veins by a healthcare provider, and the dosage will vary based on the specific treatment and may change over time. To ensure safety and effectiveness, it is essential to follow your doctor's instructions precisely. Taking this medication incorrectly or in higher doses than prescribed can lead to severe side effects.

Common side effects of Besponsa 1mg Injection include decreased blood cells, infection, fatigue, hemorrhage, fever, nausea, headache, increased liver enzymes, and abdominal pain. If these side effects are bothersome or seem severe, do not hesitate to inform your doctor. It is important to disclose any history of bleeding disorders, heart or liver conditions, previous radiation therapy, or infections to your doctor. Additionally, it is crucial to inform your doctor about all medications you are taking, as interactions may occur.

During treatment with this medication, watch out for signs such as unusual bruising or bleeding, dark stools, or a sore throat, and promptly report them to your doctor. Regular blood tests are necessary to monitor blood cell counts and organ function. Effective contraception for both males and females is essential during treatment to prevent pregnancy.


Additional Information

Habit FormingNo
Chemical ClassPeptides
Therapeutic Class-
Action Class-

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Disclaimer

The information provided on this website is to the best of our abilities to ensure it is accurate, reliable, and reviewed by a team of professionals. It should not be used to diagnose, prevent, or cure any health problem. The information presented here is not intended to create a doctor-patient relationship or replace a registered medical practitioner's advice, diagnosis, or treatment. The absence or provision of any information or warning regarding any medicine should not be assumed as an implied or explicit assurance of safety or efficacy. We highly recommend consulting your registered medical practitioner for all queries or doubts related to your medical condition. Do not ignore professional medical advice or delay seeking it based on the content encountered on our website. We intend to support, not replace, the doctor-patient relationship.

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Dr. Upasana Bhatia

MBBS - General Medicine

Last update on 11-Feb-2025