Benzz 180 Injection

By Benzz

Rx

2ml Injection in a Vial

Composition icon

Composition

Bendamustine(90mg/ml)

Manufacturer - Intas Pharmaceuticals Ltd icon

Manufacturer - Intas Pharmaceuticals Ltd

Chinubhai Centre, Off. Nehru Bridge, Ashram Road, Ahmedabad - 380009. Gujarat. India.

Expires on or after icon

Expires on or after

July, 2025

About Benzz 180 Injection

Benzz 180 Injection is a medication used in the treatment of cancer of the lymphatic system, specifically Non-Hodgkin's Lymphoma (NHL), and other types of cancer as recommended by the doctor. It is given as an injection into a vein under the supervision of a healthcare professional and should not be self-administered. The dosage may vary depending on the specific condition being treated, and it is important to follow your doctor's instructions carefully to avoid serious side effects.

The most common side effects of Benzz 180 Injection include anemia, decreased white blood cell count, infection, fatigue, nausea, and vomiting. If you experience any of these side effects or if they become severe, it is important to inform your doctor. There may be ways to manage or reduce these side effects to improve your treatment experience.

Before using Benzz 180 Injection, it is crucial to inform your doctor about your medical history, including any bleeding disorders, heart or liver disease, history of radiation treatment, or any existing infections. It is also important to disclose all medications you are currently taking as they may interact with Benzz 180 Injection. Regular blood tests will be necessary during treatment to monitor blood cell counts as well as kidney, liver, and heart function. Effective contraception is recommended for both men and women during treatment to prevent pregnancy due to the medication's impact on blood cell production.

Benzz 180 Injection 2 ml is specifically used in the treatment of Leukemia – a cancer of blood cells or blood-forming tissues. It is prescribed for Chronic lymphocytic leukemia (CLL) and indolent B-cell non-Hodgkin’s leukemia that has not responded to previous treatments. This medication contains Bendamustine, which belongs to the alkylating agents class and works by interfering with DNA and RNA transcription crucial for protein synthesis.

Some of the side effects associated with Benzz 180 Injection 2 ml include nausea, vomiting, diarrhea, stomach pain, fatigue, and injection site reactions. It is important to report any side effects to your doctor for appropriate management. Avoid using this medication if you are allergic to it or any of its components. Inform your doctor about any pre-existing conditions such as liver or kidney disease, cardiac disorders, cancer, active infections, or allergies before receiving this injection. Pregnant or breastfeeding individuals should notify their doctor due to the potential risks of embryo-fetal toxicity associated with this medication. A trained healthcare professional should administer Benzz 180 Injection 2 ml, and self-administration should be avoided.


Benefits

Benzz 180 Injection, containing Bendamustine, offers significant benefits in the treatment of various types of cancer. In Non-Hodgkin lymphoma (NHL), this medication plays a crucial role in restricting cancer growth by blocking the action of chemicals essential for cancer progression. It helps patients by impeding the spread of cancer cells and supporting the body's ability to fight infections. Patients are advised to take precautions such as avoiding crowded places, maintaining good hand hygiene, and staying well-hydrated.

For those battling blood cancer, Benzz 180 Injection is a potent and effective treatment that targets and kills cancer cells. By halting the growth and multiplication of cancer cells in the blood-forming tissues, this medication supports the body in fighting infections. Patients receiving this treatment must abstain from alcohol consumption and ensure adequate hydration to optimize the treatment's effectiveness.

In cases of multiple myeloma, Benzz 180 Injection is a crucial component of the treatment plan alongside other therapies like chemotherapy. By eliminating cancerous cells and preventing their further growth and spread, this medicine helps to strengthen bones and reduce associated pain and fractures. Patients are encouraged to closely follow their doctor's guidance and may also receive additional supplements like calcium and Vitamin D3 to support their bone health.

Overall, Benzz 180 Injection's mechanism of action, which involves inhibiting DNA and RNA transcription necessary for protein synthesis, results in the shrinkage of tumor cells. This helps prevent the growth and spread of both cancerous and non-cancerous cells, ultimately improving survival rates and enhancing the quality of life for individuals undergoing treatment for chronic lymphocytic leukemia, non-Hodgkin’s lymphoma, and other related cancers.


How to use the Benzz 180 Injection

When you receive Benzz 180 Injection, a healthcare professional such as your doctor or nurse will give it to you. It comes in a 2 ml dosage, and you should not try to administer it yourself. It is important to let a trained healthcare professional handle the injection to ensure proper and safe usage. Never attempt to self-administer Benzz 180 Injection, as it should only be administered by a healthcare professional. Remember to follow your healthcare provider's instructions carefully for the best results and to avoid any potential risks.


Uses of Benzz 180 Injection

Benzz 180 Injection is commonly used in the treatment of Non-Hodgkin lymphoma (NHL), a type of blood cancer that affects the lymphatic system. It is also effective in managing multiple myeloma, another form of blood cancer. Additionally, this injection is utilized in treating Non-Hodgkin’s disease and Chronic Lymphocytic Leukemia. It is important to follow the prescribed dosage and schedule as directed by a healthcare provider when using Benzz 180 Injection for these conditions.


What conditions Benzz 180 Injection treats?

Benzz 180 Injection is used to treat Indolent B-cell Non-Hodgkin’s Leukemia and Chronic Lymphocytic Leukemia. Non-Hodgkin’s disease is a type of blood cancer that affects the lymph system, causing uncontrolled cancer cell growth in lymph nodes. Symptoms include lymph node swelling, chest pain, and night sweats. For Chronic Lymphocytic Leukemia, it involves abnormal increase of white blood cells in the bone marrow and blood, leading to symptoms such as fever and weakness.


Should you consult a doctor?

If you experience any of the following, you should seek medical attention when using Benzz 180 Injection for the treatment of conditions such as Non-Hodgkin's Lymphoma (NHL) or other cancers:

1. Severe Side Effects: If you encounter severe side effects such as persistent anemia, low white blood cell count, infections, extreme fatigue, continuous nausea or vomiting, high fever, or significant mucosal inflammation, it is important to contact your doctor promptly.

2. Worsening Symptoms: If your symptoms worsen over time or do not improve as expected despite treatment with Benzz 180 Injection, it is a sign that you should consult your doctor for further evaluation and guidance.

3. Concerns About Medication: If you have concerns about how you are taking the medication, or if you suspect that you may have taken too much of the injection, seek medical advice immediately to avoid any serious side effects or complications.

4. Persistent Issues: If you have ongoing medical conditions such as bleeding disorders, heart or liver disease, or if you develop any new infections while undergoing treatment with Benzz 180 Injection, inform your doctor promptly for appropriate management.

Remember to always follow your doctor's instructions, attend scheduled appointments, and keep them informed about any changes or concerns regarding your health while using Benzz 180 Injection. Regular monitoring and communication with your healthcare provider are essential for safe and effective treatment.


Side effects of Benzz 180 Injection

When using Benzz 180 Injection, some individuals may experience side effects, although most of these effects usually subside as the body gets used to the medication. It is important to note that if these side effects persist or cause concern, it is advisable to consult a healthcare provider. Some of the potential side effects associated with Benzz 180 Injection include anemia (low red blood cell count), decreased white blood cell count, infections, fatigue, nausea, fever, vomiting, low blood platelets, mucosal inflammation, diarrhea, back pain, stomach pain, cough, bruising or bleeding gums, pain at the injection site, anorexia, constipation, decreased platelet count, rashes, decreased weight, and injection site reactions.


Safety advice

scroll

liver

Benzz 180 Injection must be used carefully in individuals with liver disease. It is crucial to let your doctor know if you have any existing liver issues before starting Benzz 180 Injection 2 ml. Based on your liver condition, the dosage of this medication may need to be adjusted, or your doctor might suggest a different treatment. It is important to note that individuals with severe liver disease are not recommended to use Benzz 180 Injection 2 ml. Always consult your doctor for appropriate guidance regarding the use of Benzz 180 Injection if you have liver concerns.

scroll

kidney

Benzz 180 Injection is generally considered safe for individuals with kidney disease, with no dose adjustments likely necessary. However, inform your doctor if you have a history of kidney issues. Avoid if your CrCl is <40 ml/min.

scroll

alcohol

It is advised to limit or avoid alcohol when taking Benzz 180 Injection, as it could potentially worsen your condition. Consult your doctor regarding alcohol consumption with this medication.

scroll

driving

It is not clear if Benzz 180 Injection affects driving abilities. Avoid driving if you have symptoms impacting focus or reaction time.

scroll

pregnancy

Benzz 180 Injection should not be used during pregnancy due to the risk it poses to the developing baby. In certain life-threatening situations, a doctor may prescribe it if benefits outweigh risks. Consult your doctor before use. Benzz 180 Injection 2 ml can harm the fetus, so inform your doctor if pregnant or planning pregnancy. Use effective birth control during treatment.

scroll

breastfeeding

Benzz 180 Injection is unsafe to use while breastfeeding, as it may harm the baby. Nursing mothers should inform their doctor before taking Benzz 180 Injection 2 ml and avoid breastfeeding during treatment.


Consumption warning before consuming Benzz 180 Injection

Before using Benzz 180 Injection 2 ml, it is crucial to consider certain factors to ensure your safety. If you have any known allergies to this injection or its components, it's best to avoid it. Inform your doctor about your complete medical history, including current medications, to prevent any potential side effects or interactions. Individuals with a history of liver/kidney disease, cardiac disorders, cancer, active infections, skin problems, or allergic conditions should disclose this information to their healthcare provider. Be aware that Benzz 180 Injection 2 ml may lead to myelosuppression, active infections, severe skin reactions, tumor lysis syndrome, other malignancies, and hypersensitivity reactions in some patients, necessitating careful monitoring throughout treatment. Additionally, this injection can cause embryo-fetal toxicity, making it important to inform your doctor if you are pregnant or planning to conceive. Breastfeeding mothers should consult their oncologist regarding the safety of using this medication. It is not recommended for use in children due to the lack of established safety and efficacy data.


Disease interactions

Before receiving Benzz 180 Injection 2 ml, it is important to inform your doctor about any existing kidney or liver disease, skin diseases, or infections you may have. This information is crucial as these conditions could potentially interact with the drug and affect its effectiveness or cause adverse reactions. By disclosing your medical history related to these diseases, your doctor can determine the best course of action to ensure your safety and the optimal outcome of the treatment.


What if you forgot to take Benzz 180 Injection?

If you forget to take a dose of Benzz 180 Injection, try to take it as soon as you remember. But if it's close to the time for your next dose, just skip the missed dose and continue with your regular dosing schedule. It's important not to take a double dose to make up for the missed one. Remember to always follow your prescribed dosing instructions carefully to ensure the best effectiveness of the medication.


Related lab tests

Related Lab Tests for monitoring patients receiving Benzz 180 Injection include Albumin/Globulin Ratio, Serum test to evaluate protein levels in the blood. This test helps in assessing liver and kidney function as well as overall nutritional status. Calcium levels should also be monitored regularly as Benzz 180 Injection can affect calcium metabolism. A Complete Blood Count (CBC) is important to check for any changes in red blood cells, white blood cells, and platelets that may occur during treatment. Kidney Function Tests are essential to evaluate the kidneys' ability to filter waste products from the blood. Lastly, a Peripheral Smear Examination can provide information about the size, shape, and number of different blood cell types, helping to monitor for any potential adverse effects of Benzz 180 Injection on blood cells.


Additional Information

Habit FormingNo
Chemical ClassMechlorethamine Derivative, Alkylating Agent, {Nitrogen Mustard Drug}
Therapeutic Class-
Action ClassAlkylating agent

FAQs


Disclaimer

The information provided on this website is to the best of our abilities to ensure it is accurate, reliable, and reviewed by a team of professionals. It should not be used to diagnose, prevent, or cure any health problem. The information presented here is not intended to create a doctor-patient relationship or replace a registered medical practitioner's advice, diagnosis, or treatment. The absence or provision of any information or warning regarding any medicine should not be assumed as an implied or explicit assurance of safety or efficacy. We highly recommend consulting your registered medical practitioner for all queries or doubts related to your medical condition. Do not ignore professional medical advice or delay seeking it based on the content encountered on our website. We intend to support, not replace, the doctor-patient relationship.

4776.89

Inclusive of all taxes

Content verified by

chevron-right

Dr. Upasana Bhatia

MBBS - General Medicine

Last update on 11-Feb-2025