Azadine 150 Injection

By Azadine

Rx

1 Injection in a Vial

Composition icon

Composition

Azacitidine(150mg)

Manufacturer - Intas Pharmaceuticals Ltd icon

Manufacturer - Intas Pharmaceuticals Ltd

Chinubhai Centre, Off. Nehru Bridge, Ashram Road, Ahmedabad - 380009. Gujarat. India.

Expires on or after icon

Expires on or after

July, 2025

About Azadine 150 Injection

Azadine 150 Injection is a medication used to treat certain types of blood cancer, specifically in adult patients with all subtypes of Myelodysplastic Syndrome (MDS). It may also be prescribed for other conditions as determined by your doctor.

This injection is administered under the supervision of a medical professional, who will determine the appropriate dosage and frequency based on your treatment needs. It is crucial to follow your doctor's instructions precisely to avoid serious side effects. While it may take some time to notice the benefits of Azadine 150 Injection, it is important not to stop the treatment unless advised by your doctor.

Common side effects of Azadine 150 Injection include reactions at the injection site like pain, swelling, and redness, as well as symptoms like vomiting, weakness, and nausea. If these side effects are bothersome or severe, it is important to inform your doctor. Regular blood tests are necessary to monitor your blood cells, heart, liver, and kidneys during treatment with this medication.

Azadine 150 Injection contains Azacitidine, which belongs to a group of medicines called anti-metabolites. It is used to address higher-risk myelodysplastic syndromes, chronic myelomonocytic leukaemia, and acute myeloid leukaemia by preventing the growth of cancer cells. This medication supports the bone marrow in producing normal blood cells and eliminates abnormal cells in the bone marrow.

It is essential to disclose to your doctor any existing liver or kidney conditions and the medications you are currently taking, as interactions with other drugs are possible. Azadine 150 Injection should not be used during pregnancy or while breastfeeding. If you become pregnant while on this medication, seek immediate medical advice. This medicine is not recommended for children, as its safety and effectiveness for this group have not been established. Be proactive in discussing your health status and medications with your doctor to ensure proper management of any potential side effects or interactions.


Benefits

Azadine 150 Injection offers significant benefits in the treatment of two serious conditions - blood cancer (leukemia) and myelodysplastic syndrome. In cases of blood cancer, this medication works by killing or halting the growth of cancer cells while also preventing them from multiplying further. For patients with myelodysplastic syndrome, which is a group of disorders where the bone marrow produces abnormal blood cells, Azadine 150 Injection is highly effective in addressing this issue.

The main advantage of Azadine 150 Injection lies in its ability to target and inhibit the growth of cancer cells, helping to restore the proper functioning of the bone marrow. By incorporating into the genetic material of the cells, the active ingredient Azacitidine interferes with the production of new DNA and RNA. This crucial mechanism corrects the abnormalities in the maturation and growth of young blood cells in the bone marrow, thereby addressing the root cause of myelodysplastic disorders.

Furthermore, by discussing the risks and benefits with your doctor before starting treatment, you can ensure that you are well-informed about the potential outcomes. It is important to note that Azadine 150 Injection is a potent and toxic medicine, underlining the necessity of careful consideration and medical supervision during its use. Additionally, it is advised to avoid alcohol consumption while undergoing treatment and to stay adequately hydrated by drinking plenty of water.

Overall, the benefits of Azadine 150 Injection in treating blood cancer and myelodysplastic syndrome are considerable, offering patients a targeted and effective therapy option to combat these challenging conditions.


How to use the Azadine 150 Injection

To use Azadine 150 Injection, you will need to have a qualified physician or nurse administer the medication for you. It is important not to try to self-administer this injection. The healthcare professional will carefully follow the correct procedure for giving you the Azadine 150 mg Injection to ensure your safety and the effectiveness of the treatment. Please do not attempt to use this medication on your own, always rely on a trained medical professional to administer it for you.


Uses of Azadine 150 Injection

Azadine 150 Injection is used in the treatment of blood cancer, specifically for Myelodysplastic syndrome (MDS). It is also beneficial in managing chronic myelomonocytic leukaemia (CMML) and acute myeloid leukaemia (AML). It is an important medication for patients with these conditions as it helps in controlling the progression of the diseases and improving quality of life.


What conditions Azadine 150 Injection treats?

Azadine 150 Injection is used in the treatment of various blood cancers, including myelodysplastic syndromes, chronic myelomonocytic leukaemia, and acute myeloid leukaemia. Myelodysplastic syndromes involve immature blood cells in the bone marrow that fail to mature into healthy cells, leading to symptoms like shortness of breath, fatigue, pale skin, and easy bleeding. Chronic myelomonocytic leukaemia is characterized by an excess of monocytes in the blood, presenting symptoms such as tiredness, infections, and abdominal discomfort. Acute myeloid leukaemia, on the other hand, results in excess immature white blood cells in the blood and bone marrow, causing symptoms like fever, fatigue, and bruising.


Should you consult a doctor?

If after receiving Azadine 150 Injection you experience persistent injection site reactions such as pain, swelling, or redness, along with vomiting, weakness, or nausea, it is important to consult your doctor. Additionally, if you notice any symptoms of decreased potassium levels in your blood, bruising, fever, chills, diarrhea, or constipation, seeking medical advice promptly is recommended. It is essential to inform your doctor if these side effects bother you or appear severe, as there may be ways to manage or alleviate them. Regular monitoring through blood tests is necessary to ensure your blood cells, heart, liver, and kidneys are functioning well. Remember to disclose any existing liver or kidney issues, as well as all medications you are taking, to avoid any potential interactions. If you are pregnant or breastfeeding, Azadine 150 Injection is not recommended, and it is crucial to discuss alternative options with your healthcare provider.


Side effects of Azadine 150 Injection

When using Azadine 150 Injection, some side effects may occur, but most of them are temporary and don't typically need medical attention as your body becomes accustomed to the medication. However, if these side effects persist or cause concern, it is important to consult your doctor. Common side effects of Azadine 150 Injection include injection site reactions such as pain, swelling, and redness. Other possible side effects are vomiting, weakness, nausea, decreased potassium level in the blood, bruising, fever, chills, diarrhea, and constipation. Additionally, users may also experience a decrease in blood count including red blood cells, white blood cells, and platelets. This can manifest as symptoms like nausea, vomiting, diarrhea, constipation, headache, tiredness, dizziness, and even pneumonia. Some individuals may also notice injection site reactions like redness, pain, or skin reactions. If any of these side effects persist or become bothersome, seeking medical advice is recommended.


Safety advice

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liver

When using Azadine 150 Injection, it's important to be cautious if you have any liver disease. Your doctor may need to adjust the dosage of the injection accordingly, so always consult with healthcare provider before using it. Patients with advanced liver cancer are advised not to use Azadine 150 Injection. If you have a history of liver disease or severe liver impairment, make sure to inform your doctor before taking Azadine 150 Injection to ensure safe use of the medication.

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kidney

Azadine 150 Injection may require dose adjustment in patients with kidney disease. Inform your doctor if you have a history of kidney disease before using this medication. Monitoring for kidney impairment is recommended.

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alcohol

Consult your doctor when consuming alcohol with Azadine 150 Injection.

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driving

When using Azadine 150 Injection, be cautious when driving as it may cause side effects like tiredness, dizziness, affecting your ability to drive. Avoid driving if you experience any side effects that impair your driving skills.

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pregnancy

Azadine 150 Injection is not safe to use during pregnancy due to potential risks to the developing baby. It falls under pregnancy category D. Your doctor may recommend it in life-threatening situations only if benefits outweigh risks. It is important to consult your doctor if you are pregnant or become pregnant while using Azadine 150 Injection.

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breastfeeding

Azadine 150 Injection is unsafe during breastfeeding due to potential toxicity to the baby. It's unclear if Azacitidine transfers into breast milk. Breastfeeding should be avoided while using Azadine 150 mg Injection 1's.


Consumption warning before consuming Azadine 150 Injection

Before using Azadine 150 mg Injection 1's, it's essential to be aware of certain conditions that might make it unsafe for consumption. Do not take this injection if you are allergic to any of its ingredients, have advanced liver cancer, or are breastfeeding. Prior to using this medication, inform your doctor if you have a low count of platelets, red or white blood cells, a heart condition or history of heart attack, as well as lung, kidney, or liver diseases. Pay close attention to any warning signs while on this medication and seek immediate medical help if you notice symptoms such as liver failure (jaundice, abdominal bloating, shaking, drowsiness, and easy bruising), kidney failure (back pain, increased thirst, swelling of legs and feet, reduced passing of water, dizziness, rapid pulse, nausea, vomiting, reduced appetite, confusion, fatigue, or restlessness), fever, pneumonia (shortness of breath or chest pain with fever), low platelet levels (bleeding such as blood in stool due to stomach bleeding), or allergic reactions (rash, difficulty breathing, itching, swelling of lips).


Disease interactions

When using Azadine 150 Injection, it is crucial to inform your doctor if you have a liver tumor, or if you are experiencing liver or kidney problems. These conditions can affect how your body processes the medication, potentially leading to altered effectiveness or increased risk of side effects. By disclosing this information to your healthcare provider, they can carefully monitor your treatment and adjust the dosage as needed to ensure your safety and optimize the therapeutic benefits of Azadine 150 Injection.


Related lab tests

Related Lab Tests:

When using Azadine 150 Injection, there are several important lab tests that may be relevant for monitoring your health. These tests include Bone Marrow Smear Microscopy Examination, which looks at the cells in your bone marrow to assess for any abnormalities or diseases. Additionally, a Complete Blood Count (CBC) is important to check the levels of different blood cells in your body, such as red blood cells, white blood cells, and platelets. Lastly, a Peripheral Smear Examination may be conducted to visually examine the size, shape, and number of your blood cells under a microscope.

These lab tests can provide valuable information about your overall health and how your body is responding to treatment with Azadine 150 Injection. It is important to follow your healthcare provider's recommendations for when to undergo these tests and to discuss the results with them. Be sure to stay informed and proactive about your health by regularly monitoring these key lab tests.


Additional Information

Habit FormingNo
Chemical ClassPyrimidine Nucleoside Analogue
Therapeutic ClassANTI NEOPLASTICS
Action ClassAntimetabolites

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Disclaimer

The information provided on this website is to the best of our abilities to ensure it is accurate, reliable, and reviewed by a team of professionals. It should not be used to diagnose, prevent, or cure any health problem. The information presented here is not intended to create a doctor-patient relationship or replace a registered medical practitioner's advice, diagnosis, or treatment. The absence or provision of any information or warning regarding any medicine should not be assumed as an implied or explicit assurance of safety or efficacy. We highly recommend consulting your registered medical practitioner for all queries or doubts related to your medical condition. Do not ignore professional medical advice or delay seeking it based on the content encountered on our website. We intend to support, not replace, the doctor-patient relationship.

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Dr. Upasana Bhatia

MBBS - General Medicine

Last update on 11-Feb-2025