Avastin 400mg Injection
By Avastin
Rx
16ml Injection in a Vial

Composition
Bevacizumab(400mg)

Manufacturer - Roche Products India Pvt Ltd
1503, 15th Floor, 'The Capital', Plot no. C-70, Behind ICICI Bank, BKC, Bandra (E) , Mumbai 400051

Expires on or after
July, 2025
About Avastin 400mg Injection
Avastin 400mg Injection is a powerful anticancer medication designed to combat various types of cancers such as colon, rectum, lung, kidney, brain, ovarian, and cervical cancer. This medication works by hindering the growth of new blood vessels that nourish tumors, effectively putting a stop to their expansion. Introduced as a first-line treatment option when used in conjunction with other cancer medications, Avastin 400mg Injection is administered through infusion, where a small needle is inserted into a vein or via a port implanted beneath the skin. Your doctor will carefully determine the appropriate dosage and treatment duration while monitoring you for any signs of an infusion reaction, including high blood pressure and breathing difficulties.
It is crucial to continue the regimen of Avastin 400mg Injection as long as your condition remains under control and the side effects remain manageable. Your doctor will assess the necessity of discontinuing the treatment based on your individual response. Regular monitoring of blood pressure and urine protein levels may be recommended by your healthcare provider while you are on this medication.
While Avastin 400mg Injection is effective in fighting cancer, it may also lead to certain common side effects such as rectal bleeding, taste alterations, and headaches. It is vital to disclose your use of this medication to your healthcare provider before undergoing any surgical procedures, as Avastin has been associated with a potential decrease in wound healing ability. Additionally, this medication may increase the risk of bleeding, so it is important to promptly inform your doctor if you notice any unusual bleeding episodes.
If you are pregnant, planning a pregnancy, or breastfeeding, it is essential to inform your healthcare provider before initiating Avastin treatment. As this medication can interact with a variety of other drugs, it is advisable to provide a comprehensive list of all medications you are currently using to your healthcare team. By staying informed and communicating openly with your doctor, you can ensure the safe and effective use of Avastin 400mg Injection in your cancer treatment journey.
Benefits
Avastin 400mg Injection offers a range of benefits in treating various types of cancers. In cases of colon and rectal cancer, it not only treats existing cancer but also reduces the risk of developing further cancerous growths. By killing or inhibiting the growth of cancer cells, Avastin 400mg Injection effectively prevents the multiplication of these harmful cells in the colon or rectum. In non-small cell lung cancer, this medication is effective either alone or in combination with other treatments. It is crucial to discuss the potential risks and benefits with your doctor before starting treatment. Moreover, in kidney cancer, Avastin 400mg Injection addresses symptoms such as blood in urine, weight loss, and fatigue while halting the advancement of cancer to other parts of the body. Similarly, for patients with brain tumors, ovarian cancer, and cervical cancer, this medication works by stopping the growth and multiplication of cancer cells, offering an effective treatment option. However, it is important to note that Avastin 400mg Injection is a potent and toxic medicine, requiring careful adherence to doctor's instructions and a discussion of risks and benefits prior to use.
How to use the Avastin 400mg Injection
To use Avastin 400mg Injection, you should let your doctor or nurse administer the medicine to you. It comes in a 16 ml vial and must be given by a healthcare professional. It is important not to try to administer this injection on your own. This medication is meant to be administered by a trained professional to ensure proper dosage and safe administration. Be sure to follow your healthcare provider's instructions carefully and do not attempt to self-administer this injection. Your well-being is our top priority, and following these guidelines will help ensure the safe and effective use of Avastin 400mg Injection.
Uses of Avastin 400mg Injection
Avastin 400mg Injection is used in the treatment of various types of cancers such as colon cancer, rectal cancer, non-small cell lung cancer, kidney cancer, brain tumor, ovarian cancer, and cervical cancer. It is particularly helpful in managing metastatic breast cancer, non-small cell lung cancer, kidney cancer, cervical cancer, epithelial ovarian cancer, fallopian tube cancer, primary peritoneal cancer, as well as colorectal cancer. Avastin 400mg Injection plays a crucial role in targeting these specific types of cancer and is considered as part of the treatment plan for patients diagnosed with these conditions.
What conditions Avastin 400mg Injection treats?
Cancer is a disease where cells in a certain body area grow and replicate without control. These cancerous cells can invade and harm nearby healthy tissues and organs. Cancer usually starts in one spot and can spread to other parts of the body. Mutations in genes that control cell growth are what cause cancer to develop. These mutations make cells divide and multiply uncontrollably, leading to the formation of tumors. Treatment options for cancer often include surgery, chemotherapy, radiotherapy, bone marrow (stem cell) transplantation, immunotherapy, and targeted drug therapy.
Should you consult a doctor?
If you experience rectal bleeding, changes in taste, headaches, nosebleeds, back pain, dry skin, high blood pressure, protein in urine, or nasal inflammation while taking Avastin 400mg Injection, it is essential to consult your doctor. These symptoms may indicate potential side effects that require medical attention. Additionally, if you notice any unusual bleeding or have concerns about your condition, it is important to seek immediate medical advice. Inform your healthcare provider if you are pregnant, planning to become pregnant, or breastfeeding, as Avastin 400mg Injection may have implications for these scenarios. Moreover, if you are scheduled for surgery, it is crucial to disclose your medication to avoid complications with wound healing. Be vigilant about any changes in your health status and always communicate openly with your doctor about any concerns or new development while on Avastin 400mg Injection.
Side effects of Avastin 400mg Injection
When using Avastin 400mg Injection, certain side effects may occur as your body gets used to the medication. Common side effects include rectal bleeding, taste changes, headaches, nosebleeds, back pain, dry skin, high blood pressure, presence of protein in urine, and nasal inflammation. Additionally, some users may experience constipation, loss of appetite, fever, nosebleeds, changes in speech, changes in taste perception, hoarseness in voice, and unexplained weight loss. Remember that most side effects are temporary and will fade over time, but if they persist or cause concern, do not hesitate to consult your healthcare provider.
Safety advice

liver
Avastin 400mg Injection appears to be safe for use in individuals with liver disease, as per the limited data available. It is suggested that adjusting the dosage of Avastin 400mg Injection may not be necessary for patients with liver issues. It is advisable to consult your doctor before using this medication to ensure it is suitable for your specific condition.

kidney
Avastin 400mg Injection is likely safe for use in patients with kidney disease. Available data suggests no need for dose adjustment. Consult your doctor for guidance.

alcohol
It is not certain if it is safe to drink alcohol while taking Avastin 400mg Injection. Please consult your doctor.

driving
Be cautious when driving after using Avastin 400mg Injection due to reported side effects like sleepiness and fainting, which can affect your driving ability.

pregnancy
Avastin 400mg Injection may not be safe to use during pregnancy. Limited human studies and animal studies have shown negative effects on the developing baby. Your doctor will consider the benefits and risks before prescribing it to you. Please consult your doctor before using Avastin 400mg Injection.

breastfeeding
Avastin 400mg Injection is likely unsafe during breastfeeding. Limited data indicates it may pass into breastmilk and harm the baby.
Consumption warning before consuming Avastin 400mg Injection
Before consuming Bevarest-400 Injection 16 ml, it is crucial to seek medical supervision for your safety. Your doctor will closely monitor your condition during the treatment. Inform your doctor about any past allergic reactions to Avastin 400mg Injection or other medications. If you are pregnant, it is advised to avoid taking Avastin 400mg Injection and use effective contraception during the treatment and for 6 months after the last dose. Be aware that this injection may cause drowsiness and fainting, so refrain from driving while undergoing treatment. Notify your doctor if you have a history of high blood pressure, heart attack, stroke, bleeding disorders, or recent surgeries. Avoid breastfeeding during the treatment period and for 6 months after the final dose. Additionally, do not receive any vaccinations without your doctor's approval as Avastin 400mg Injection may elevate the risk of bleeding. If you experience unusual bleeding or bruising, consult your doctor immediately.
Disease interactions
When using Avastin 400mg Injection, it is crucial to inform your healthcare provider about any previous or current infections, bleeding disorders, fistula formation, GI perforation, hypertension, PRES (Posterior Reversible Encephalopathy Syndrome), proteinuria, and thromboembolic disorders. These conditions can potentially interact with the medication, affecting its effectiveness or causing adverse reactions. By disclosing this information to your doctor, they can make informed decisions about the appropriateness of Avastin 400mg Injection for your specific health circumstances. It is important to prioritize your safety and well-being by ensuring open communication with your healthcare provider regarding any pre-existing medical conditions.
What if you forgot to take Avastin 400mg Injection?
If you forget to take a dose of Avastin 400mg Injection, it is important to speak with your doctor without delay. Consulting your doctor is essential to ensure you receive proper guidance on how to proceed after missing a dose of this medication. It is crucial not to take any extra doses to make up for the missed one without first consulting with your healthcare provider. Your doctor will be able to provide you with the necessary advice tailored to your specific situation.
Related lab tests
When considering 'Avastin 400mg Injection', there are several related lab tests that may be important to consider. These include Carcino Embryonic Antigen, which is a blood test that can help in monitoring certain types of cancer. Another essential test is the Complete Blood Count (CBC), which provides information on different components of the blood like red blood cells and white blood cells. Human Papilloma Virus (HPV) testing can help in detecting the presence of this virus which is linked to certain types of cancers. Additionally, the Papanicolaou (PAP) Cytology test, commonly known as a Pap smear, is crucial for screening cervical cancer in women. These lab tests play a significant role in assessing health status and detecting potential issues that may require further evaluation or treatment.
Additional Information
Habit Forming | No |
Chemical Class | Monoclonal Antibody |
Therapeutic Class | - |
Action Class | - |
FAQs
Disclaimer
The information provided on this website is to the best of our abilities to ensure it is accurate, reliable, and reviewed by a team of professionals. It should not be used to diagnose, prevent, or cure any health problem. The information presented here is not intended to create a doctor-patient relationship or replace a registered medical practitioner's advice, diagnosis, or treatment. The absence or provision of any information or warning regarding any medicine should not be assumed as an implied or explicit assurance of safety or efficacy. We highly recommend consulting your registered medical practitioner for all queries or doubts related to your medical condition. Do not ignore professional medical advice or delay seeking it based on the content encountered on our website. We intend to support, not replace, the doctor-patient relationship.
₹123506
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Content verified by

Dr. Abdullah Khan
MBBS - General Medicine
Last update on 01-Oct-2024