Amfosted 500 Injection

By Amfosted

Rx

1 Injection in a Vial

Composition icon

Composition

Amifostine(500mg)

Manufacturer - Therdose Pharma Pvt Ltd icon

Manufacturer - Therdose Pharma Pvt Ltd

Plot No's : 118 - 120, Road No.6, ALEAP IE, Pragathi Nagar, Gajularamaram Village, Kukatpally, Hyderabad ,Telangana - 500 072, India.

Expires on or after icon

Expires on or after

July, 2025

About Amfosted 500 Injection

Amfosted 500 Injection is a medication used to address specific health issues related to cancer treatment. It serves the purpose of preventing dryness in the mouth following radiation therapy for head and neck cancer. Moreover, it aids in reducing the harmful impact of chemotherapy on the kidneys during treatment with cisplatin, a medication commonly used for cancer treatment.

This injection is delivered directly into a vein through intravenous infusion under the supervision of a healthcare professional. The dosage and frequency of administration will be determined by your doctor based on your individual treatment needs. It is crucial to adhere to the prescribed dosage and administration instructions to avoid any serious side effects that may arise from incorrect usage or overdosing.

Clinical benefits from using Amfosted 500 Injection may take time to manifest, potentially requiring several weeks or months for noticeable results. It is essential to continue the treatment regimen as directed by your doctor and to not discontinue its use without medical advice.

Common side effects associated with Amfosted 500 Injection include nausea, vomiting, decreased blood pressure, dizziness, and flushing. If any of these side effects persist or become bothersome, consult your doctor for further guidance. Staying properly hydrated before administration is advised, and regular monitoring of blood pressure is typically conducted before and during infusion.

Prior to initiating treatment with Amfosted 500 Injection, inform your doctor about any existing heart conditions, ongoing medication use, or any history of infections being treated. This medication may interact with other drugs, emphasizing the importance of disclosing all current medications to your healthcare provider.

Amfosted 500 Injection 1's, which contains the active ingredient Amifostine, falls under the category of cytoprotective agents. It is utilized for diminishing cumulative kidney toxicity associated with cisplatin therapy in ovarian cancer patients and reducing the occurrence of severe dry mouth in individuals undergoing radiation treatment for head and neck cancer post-surgery.

Potential side effects of Amfosted 500 Injection 1's may include nausea, vomiting, injection site pain, and reactions at the injection site. Notify your doctor if these side effects persist. This medication is to be administered by a healthcare professional in a hospital setting and should not be self-administered.

Individuals with known allergies to Amfosted 500 Injection 1's or its components should avoid its use. Furthermore, inform your doctor of any history of liver or kidney disease, cardiac issues, skin disorders, or low calcium levels before starting treatment with this medication. It is essential to note that Amfosted 500 Injection 1's is not recommended during pregnancy due to potential risks of embryo-fetal toxicity, and breastfeeding should be avoided while on this medication.


Benefits

Amfosted 500 Injection offers multiple benefits to patients undergoing treatment for certain medical conditions. One key benefit is its effectiveness in reducing dryness in the mouth following radiotherapy for head and neck cancer. This common side effect can be quite uncomfortable, but Amfosted 500 Injection helps alleviate the discomfort, improving the patient's quality of life during recovery. Additionally, this medication plays a crucial role in protecting the kidneys from potential damage caused by cisplatin, a chemotherapy drug commonly used in the treatment of ovarian cancer. By safeguarding the kidneys, Amfosted 500 Injection ensures that patients can continue their cancer treatment without risking additional complications. It is essential to note that Amfosted 500 Injection should only be administered by healthcare professionals to ensure proper dosage and monitoring. Overall, the benefits of Amfosted 500 Injection extend beyond symptom relief, offering vital support to patients navigating through challenging cancer treatments.


How to use the Amfosted 500 Injection

When it comes to using Amfosted 500 Injection, it is important to follow your doctor's or nurse's instructions carefully. This medicine should only be administered by a healthcare professional, so it is essential not to attempt to self-administer it. Your doctor or nurse will determine the correct dosage and frequency of the injections based on your specific medical condition. They will inject the medicine into a muscle or vein, and it is crucial to receive the injection exactly as directed. If you have any questions or concerns about how to use Amfosted 500 Injection, do not hesitate to discuss them with your healthcare provider. Remember, this medication should only be administered by a trained professional for your safety and well-being.


Uses of Amfosted 500 Injection

Amfosted 500 Injection is primarily used in the treatment of dryness in the mouth that occurs as a result of undergoing radiotherapy for head and neck cancer. This injection helps to alleviate the discomfort and dry feeling in the mouth that may result from the side effects of radiotherapy. By targeting this specific issue, Amfosted 500 Injection aims to provide relief and improve the overall quality of life for individuals facing this challenge. It is important to follow the prescribed dosage and administration guidance provided by healthcare professionals to ensure the best possible outcome in managing dryness in the mouth post-radiotherapy.


What conditions Amfosted 500 Injection treats?

Amfosted 500 Injection is used to decrease dryness in the mouth caused by radiation treatment after surgery for head and neck cancer. It protects the kidneys from harmful effects of chemotherapy medicine cisplatin in patients receiving this treatment for ovarian cancer. It is administered by a healthcare professional and should not be self-administered.


Should you consult a doctor?

If you experience persistent nausea, vomiting, decreased blood pressure, hiccups, sleepiness, dizziness, flushing, fever, or chills while using Amfosted 500 Injection, it is important to seek medical advice. These symptoms may indicate potential serious side effects that require attention from your healthcare provider. It is also crucial to consult with your doctor if the side effects do not go away or if they bother you. Additionally, if you have any underlying heart conditions such as irregular heartbeat or heart failure, or if you are taking medications for infections, inform your doctor before starting Amfosted 500 Injection. Regular monitoring of your blood pressure before and during the infusion is recommended to ensure your safety during treatment. If you have any concerns about the effects of this medicine, do not hesitate to discuss them with your healthcare team. Your doctor will determine the appropriate course of action based on your individual circumstances.


Side effects of Amfosted 500 Injection

When using Amfosted 500 Injection, you may experience certain side effects. Most of these side effects are temporary and fade away as your body gets used to the medication. Some common side effects include nausea, vomiting, decreased blood pressure, hiccups, sleepiness, dizziness, flushing (a warm feeling in the face, ears, neck, and trunk), fever, and chills. It is important to consult your doctor if these side effects persist or if you have any concerns about them.


Safety advice

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liver

Limited information is available on the use of Amfosted 500 Injection in patients with liver disease. It is important to consult your doctor before using this medication to ensure it is safe for you.

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kidney

Amfosted 500 Injection may be safe for use in patients with kidney disease. Available data indicates that dose adjustment for kidney issues may not be necessary. It is advisable to consult your doctor for guidance.

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alcohol

Consult your doctor when consuming alcohol with Amfosted 500 Injection.

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driving

Caution should be exercised when driving if you are unsure of how Amfosted 500 Injection affects you. Avoid driving if you have symptoms that impact focus and reaction time.

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pregnancy

Amfosted 500 Injection may not be safe to use during pregnancy. Limited human studies suggest potential harm to the developing baby based on animal studies. Your doctor will consider the benefits and risks before prescribing. Please consult your doctor.

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breastfeeding

Amfosted 500 Injection is likely safe while breastfeeding. Human data shows no significant risk to the baby.


Consumption warning before consuming Amfosted 500 Injection

Before consuming Amfosted 500 Injection, it is important to be aware of certain considerations. This medication is primarily used to prevent dryness in the mouth post-radiotherapy for head and neck cancer and to reduce the harmful effects of chemotherapy on the kidneys during cisplatin treatment. It is administered through an injection into a vein under medical supervision. The dosage and frequency will be determined by your doctor based on your specific condition, and it is crucial to strictly adhere to their instructions to avoid severe side effects.


Common side effects of Amfosted 500 Injection include nausea, vomiting, decreased blood pressure, dizziness, and flushing. If these symptoms persist or become bothersome, consult your doctor promptly. It is recommended to maintain proper hydration before taking this medication. Additionally, individuals with heart conditions or those on medications for infections should inform their doctor before starting Amfosted 500 Injection. Regular blood pressure monitoring is necessary during the infusion process.


It is essential to discuss all current medications with your healthcare provider, as interactions can occur. The benefits of Amfosted 500 Injection may take time to manifest, so continue treatment as directed unless otherwise advised by your doctor.


Additional Information

Habit FormingNo
Chemical ClassPhosphorylated aminosulfhydryl compound
Therapeutic Class-
Action ClassCytoprotective agents- Kidney & Salivary gland

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Disclaimer

The information provided on this website is to the best of our abilities to ensure it is accurate, reliable, and reviewed by a team of professionals. It should not be used to diagnose, prevent, or cure any health problem. The information presented here is not intended to create a doctor-patient relationship or replace a registered medical practitioner's advice, diagnosis, or treatment. The absence or provision of any information or warning regarding any medicine should not be assumed as an implied or explicit assurance of safety or efficacy. We highly recommend consulting your registered medical practitioner for all queries or doubts related to your medical condition. Do not ignore professional medical advice or delay seeking it based on the content encountered on our website. We intend to support, not replace, the doctor-patient relationship.

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Dr. Gowri Kulkarni

MBBS - General Medicine, DNB - Psychiatry, MRCGP [INT] Family Medicine, BSIC (BACP)

Last update on 01-Oct-2024